Phenotype: increased prepulse inhibition

Phenotype associations stats

1.28% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased prepulse inhibition (50/3911)

1.21% females (47/3895) 1.26% males (49/3904)

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Gene variants with increased prepulse inhibition

Total number of significant genotype-phenotype associations: 96

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Fus
Fustm1.1(KOMP)Vlcg
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 TCP | IMPC 2.57E-10
Acvr1b
Acvr1btm1.1(KOMP)Vlcg
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 TCP | IMPC 7.06E-9
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 TCP | IMPC 1.02E-8
Clptm1l
Clptm1lem1(IMPC)J
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 2.95E-7
Pald1
Pald1em1(IMPC)KMPC
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 KMPC | IMPC 2.09E-6
Arrdc1
Arrdc1tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 2.11E-6
Skida1
Skida1tm1.1(KOMP)Wtsi
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 TCP | IMPC 2.22E-6
Dnmbp
Dnmbpem1(IMPC)Mbp
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 UC Davis | IMPC 2.52E-6
Dock9
Dock9em1(IMPC)J
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 JAX | IMPC 3.81E-6
Cav3
Cav3em1(IMPC)KMPC
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 KMPC | IMPC 3.96E-6
Sgip1
Sgip1tm1b(EUCOMM)Hmgu
HET Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global HMGU | IMPC 5.8E-6
Usp31
Usp31em1(IMPC)Marc
HOM Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 MARC | IMPC 5.99E-6
Tyk2
Tyk2tm2b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 HMGU | IMPC 6.33E-6
Mpi
Mpitm1a(EUCOMM)Wtsi
HET Female Male postnatal increased prepulse inhibition Acoustic Startle&PPI | Global prepulse inhibition MRC Harwell | MGP 6.6E-6
Spns1
Spns1tm1e(EUCOMM)Wtsi
HET Female Male postnatal increased prepulse inhibition Acoustic Startle&PPI | Prepulse inhibition - PP4 ICS | EuroPhenome 6.89E-6
Arhgap23
Arhgap23tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 BCM | IMPC 7.13E-6
Tbr1
Tbr1tm1b(KOMP)Mbp
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 UC Davis | IMPC 9.14E-6
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HOM Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 ICS | IMPC 1.06E-5
Nmb
Nmbtm1.1(KOMP)Vlcg
HOM Female postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 JAX | IMPC 1.13E-5
Uchl1
Uchl1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 MRC Harwell | IMPC 1.15E-5
Yipf5
Yipf5tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 ICS | IMPC 1.52E-5
Dkkl1
Dkkl1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 BCM | IMPC 1.54E-5
Dusp12
Dusp12em1(IMPC)Mbp
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 UC Davis | IMPC 1.59E-5
Ism2
Ism2tm3b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 BCM | IMPC 1.65E-5
Rsad1
Rsad1tm1.1(KOMP)Vlcg
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 TCP | IMPC 1.81E-5
Rcan1
Rcan1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 ICS | IMPC 1.84E-5
Cabp4
Cabp4tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 UC Davis | IMPC 2.43E-5
Ptdss1
Ptdss1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 ICS | IMPC 2.56E-5
Chchd1
Chchd1tm1.1(KOMP)Vlcg
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 TCP | IMPC 3.02E-5
Bbs7
Bbs7tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 JAX | IMPC 3.07E-5
Herc3
Herc3tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle&PPI | Prepulse inhibition - PP1 WTSI | EuroPhenome 3.13E-5
Serpina7
Serpina7em1(IMPC)J
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 3.41E-5
Pmpcb
Pmpcbtm1b(EUCOMM)Hmgu
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 BCM | IMPC 3.82E-5
Klk14
Klk14tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 HMGU | IMPC 3.88E-5
Slc44a2
Slc44a2em1(IMPC)J
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 4.81E-5
Acsm2
Acsm2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 4.93E-5
Ptpn5
Ptpn5tm1b(KOMP)Wtsi
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 4.95E-5
Iah1
Iah1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global ICS | IMPC 5.38E-5
Ntf5
Ntf5tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 ICS | IMPC 5.64E-5
Prkch
Prkchtm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 6.06E-5
Zfp536
Zfp536tm1.1(KOMP)Wtsi
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 JAX | IMPC 6.54E-5
Nsd3
Nsd3tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 MRC Harwell | IMPC 6.7E-5
Irf8
Irf8tm1b(KOMP)Wtsi
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 7.36E-5
Npm3
Npm3tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 JAX | IMPC 7.67E-5
Dnajb12
Dnajb12tm1.1(KOMP)Vlcg
HET Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 JAX | IMPC 7.67E-5
Mx2
Mx2em1(IMPC)Ics
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 ICS | IMPC 8.06E-5
Laptm4a
Laptm4atm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global ICS | IMPC 8.68E-5
Rhbdf2
Rhbdf2not yet available
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle&PPI | Prepulse inhibition - PP3 MRC Harwell | EuroPhenome 8.72E-5
Rasal3
Rasal3tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 ICS | IMPC 9.6E-5
Mphosph9
Mphosph9tm1e.1(EUCOMM)Hmgu
HOM Female Male postnatal increased prepulse inhibition Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 HMGU | IMPC 9.83E-5

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