Definition
reduced average content of platelet cells over normal
Synonyms
reduced mean platelet volume,
decreased MPV,
reduced MPV
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased mean platelet volume
Total number of significant genotype-phenotype associations: 55
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Dll1 Dll1tm1Gos |
HET | Early adult | decreased mean platelet volume | Mean platelets volume Haematology (GMC) |
HMGU EuroPhenome |
3.07×10-32 | |
| Tardbp Tardbptm1b(EUCOMM)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
6.95×10-29 | |
| Kcnj10 Kcnj10tm1b(KOMP)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
6.53×10-26 | |
| Rasgrp3 Rasgrp3em1(IMPC)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
6.95×10-13 | |
| Atp2a2 Atp2a2tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
9.20×10-12 | |
| Fbxo36 Fbxo36tm1b(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MARC IMPC |
2.75×10-11 | |
| Uqcrq Uqcrqtm1b(EUCOMM)Hmgu |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
3.43×10-10 | |
| Marchf6 Marchf6tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
3.46×10-08 | |
| Atf2 Atf2tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
5.39×10-08 | |
| Abcc2 Abcc2tm2b(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
8.84×10-08 | |
| Tox2 Tox2em1(IMPC)H |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
1.23×10-07 | |
| Cyp3a59 Cyp3a59em1(IMPC)Marc |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MARC IMPC |
2.34×10-07 | |
| Ppp2r5e Ppp2r5eem1(IMPC)Marc |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MARC IMPC |
5.58×10-07 | |
| Jmjd6 Jmjd6tm1b(EUCOMM)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
HMGU IMPC |
9.66×10-07 | |
| Gsk3a Gsk3atm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
HMGU IMPC |
1.99×10-06 | |
| Dbn1 Dbn1tm1b(KOMP)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
HMGU IMPC |
2.76×10-06 | |
| Plcz1 Plcz1em1(IMPC)H |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
3.88×10-06 | |
| Otp Otptm1b(EUCOMM)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
4.20×10-06 | |
| Stk26 Stk26tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
4.33×10-06 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
WTSI IMPC |
4.65×10-06 | |
| Cpgi11865 Cpgi11865tm1.1(NCC)WCS |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
WTSI IMPC |
5.60×10-06 | |
| Chd2 Chd2tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
TCP IMPC |
7.47×10-06 | |
| Pld5 Pld5tm1b(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
WTSI IMPC |
9.11×10-06 | |
| Clcn1 Clcn1em1(IMPC)Mbp |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
UC Davis IMPC |
1.23×10-05 | |
| Stk26 Stk26tm1b(EUCOMM)Hmgu |
HEM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
1.28×10-05 | |
| Trdmt1 Trdmt1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
1.31×10-05 | |
| Lypd2 Lypd2em1(IMPC)Marc |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MARC IMPC |
1.41×10-05 | |
| Ckb Ckbtm1.1(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
UC Davis IMPC |
1.79×10-05 | |
| Atp6v1d Atp6v1dtm1b(EUCOMM)Hmgu |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
TCP IMPC |
1.87×10-05 | |
| Cyp27a1 Cyp27a1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
UC Davis IMPC |
1.90×10-05 | |
| Fbxo25 Fbxo25em1(IMPC)Ccpcz |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
2.02×10-05 | |
| Sdc4 Sdc4tm2b(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
2.63×10-05 | |
| Tut4 Tut4tm1a(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
WTSI IMPC |
2.73×10-05 | |
| Il18rap Il18rapem1(IMPC)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
WTSI IMPC |
2.91×10-05 | |
| Selenok Selenoktm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
WTSI IMPC |
3.12×10-05 | |
| Aopep Aopeptm1b(KOMP)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
3.60×10-05 | |
| Pink1 Pink1tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
3.69×10-05 | |
| Trim37 Trim37em1(IMPC)Marc |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MARC IMPC |
3.80×10-05 | |
| Polr3d Polr3dem1(IMPC)Tcp |
HET | Late adult | decreased mean platelet volume | Mean platelet volume Hematology |
TCP IMPC |
3.91×10-05 | |
| Usp16 Usp16tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MARC IMPC |
4.43×10-05 | |
| Cul4a Cul4atm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
CCP-IMG IMPC |
4.95×10-05 | |
| Ethe1 Ethe1tm1b(EUCOMM)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
5.41×10-05 | |
| Cbx6 Cbx6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
WTSI IMPC |
6.36×10-05 | |
| Rest Resttm2b(EUCOMM)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
HMGU IMPC |
8.51×10-05 | |
| Scn4a Scn4atm2b(KOMP)Wtsi |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
9.09×10-05 | |
| Syncrip Syncriptm1b(EUCOMM)Hmgu |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
HMGU IMPC |
9.20×10-05 | |
| Prkab2 Prkab2tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
9.27×10-05 | |
| Ppp3cc Ppp3cctm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
MRC Harwell IMPC |
9.59×10-05 | |
| Cyb561a3 Cyb561a3tm2b(EUCOMM)Hmgu |
HOM | Early adult | decreased mean platelet volume | Mean platelet volume Hematology |
HMGU IMPC |
9.74×10-05 |