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Phenotype: decreased IgG1 level

Definition
less than normal immunoglobulin class G1 level
Synonyms
reduced IgG1 level
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased IgG1 level

Total number of significant genotype-phenotype associations: 2

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Aco2
Aco2Gt(EUC0050e03)Hmgu 		HET Early adult decreased IgG1 level IgG1
Immunoglobulin		 HMGU
EuroPhenome		 9.54×10-07
Pknox1
Pknox1Gt(EUCJ0079d10)Hmgu 		HET Early adult decreased IgG1 level IgG1
Immunoglobulin		 HMGU
EuroPhenome		 9.98×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Antigen Specific Immunoglobulin Assay
Immunoglobulin
Immunoglobulin concentration
Trichuris

 Phenotype associations stats

1.79% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased IgG1 level (2/112)

0.94% females (1/106) 0.95% males (1/105)

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