Definition
greater number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity
Synonyms
increased number of immature B lymphocytes,
increased number of immature B cells,
increased number of immature B-cells,
increased number of immature B-lymphocytes
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased immature B cell number
Total number of significant genotype-phenotype associations: 2
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Arhgap17 Arhgap17tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased transitional stage T1 B cell number | Transitional 1 B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased immature B cell number | Immature B cells (Hardy fraction E) - % of B220+ Bone marrow immunophenotyping |
WTSI 3i |
0.00 |