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Phenotype: decreased pre-B cell number

Definition
reduced number of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface
Synonyms
decreased pre-B lymphocyte cell number,  decreased number of pre-B cells,  reduced pre-B cell number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased pre-B cell number

Total number of significant genotype-phenotype associations: 1

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi 		HOM   Early adult decreased pre-B cell number Pre-B cells (Hardy fraction D) - % of CD45+
Bone marrow immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Bone marrow immunophenotyping

 Phenotype associations stats

0.24% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased pre-B cell number (1/425)

0.00% females (0/1) 0.00% males (0/1)



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