Definition
greater number of conventional B cells subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells
Synonyms
increased number of B-2 cells
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased B-2 B cell number
Total number of significant genotype-phenotype associations: 3
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased B-2 B cell number | Total B2 cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Lratd2 Lratd2em1(IMPC)Ccpcz |
HOM | Early adult | increased B-2 B cell number | B2B Cells Immunophenotyping |
CCP-IMG IMPC |
2.00×10-05 | |
| Timp2 Timp2em1(IMPC)Hmgu |
HOM | Late adult | increased B-2 B cell number | B2B Cells Immunophenotyping |
HMGU IMPC |
7.20×10-05 |