IMPC Gene variants with decreased germinal center B cell number
Total number of significant genotype-phenotype associations: 3
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased late germinal center B cell number | Late germinal centre B cells - % of GC cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased early germinal center B cell number | Early germinal centre B cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased germinal center B cell number | Germinal centre B cells - % of B2 cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 |