Definition
greater number of rapidly cycling mature B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA), and are involved in T-dependent immune responses; germinal center B cells are found typically in the germinal centers of lymph nodes and spleen
Synonyms
increased germinal centre B cell number
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased germinal center B cell number
Total number of significant genotype-phenotype associations: 3
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | increased early germinal center B cell number | Early germinal centre B cells - % of GC cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | increased germinal center B cell number | Germinal centre B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Ydjc Ydjctm1(KOMP)Wtsi |
HOM | Early adult | increased germinal center B cell number | Germinal centre B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 |