Phenotype: absent startle reflex

Phenotype associations stats

1.00% of tested genes with null mutations on a B6N genetic background have a phenotype association to absent startle reflex (31/3103)

0.55% females (17/3090) 0.81% males (25/3086)

Gene variants with absent startle reflex

Total number of significant genotype-phenotype associations: 42

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 5.57E-20
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 3.72E-18
Clrn1
Clrn1tm1.1(KOMP)Vlcg
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response UC Davis | IMPC 2.03E-16
Marveld2
Marveld2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 2.77E-16
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 2.77E-16
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Female postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response ICS | IMPC 2.94E-16
Baiap2l2
Baiap2l2tm1b(EUCOMM)Hmgu
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response ICS | IMPC 3.97E-15
Lat
Latem1(IMPC)Ics
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response ICS | IMPC 3.97E-15
Tmtc4
Tmtc4tm1.1(KOMP)Vlcg
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response UC Davis | IMPC 7.59E-15
Myh1
Myh1tm1b(KOMP)Wtsi
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 7.96E-14
Mx2
Mx2em1(IMPC)Ics
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response ICS | IMPC 1.93E-13
Tox
Toxtm1b(KOMP)Wtsi
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response UC Davis | IMPC 5.56E-13
Nedd4l
Nedd4ltm1b(KOMP)Wtsi
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 1.71E-12
Tomm40
Tomm40em1(IMPC)J
HET Female postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 2.25E-11
Tprn
Tprntm1.1(KOMP)Vlcg
HOM Female postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 2.25E-11
Fgf7
Fgf7tm1e.1(EUCOMM)Hmgu
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 4.69E-11
Eps8l2
Eps8l2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 3.38E-9
Prkcsh
Prkcshtm1.1(KOMP)Vlcg
HET Female postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 5.78E-9
Tardbp
Tardbptm1b(EUCOMM)Wtsi
HET Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 7.71E-9
Adgrv1
Adgrv1tm1.1(KOMP)Vlcg
HOM Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response UC Davis | IMPC 1.05E-8
Rab11fip3
Rab11fip3em1(IMPC)J
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 8.08E-8
Ust
Ustem1(IMPC)J
HET Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 8.08E-8
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 8.23E-7
Ylpm1
Ylpm1tm1b(KOMP)Wtsi
HET Female Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 1.11E-6
Slc44a2
Slc44a2em1(IMPC)J
HOM Female postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 1.66E-6
BC052040
BC052040em1(IMPC)J
HET Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response JAX | IMPC 9.29E-6
Sun1
Sun1tm1b(EUCOMM)Wtsi
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response ICS | IMPC 1.98E-5
Ypel3
Ypel3tm1.1(KOMP)Vlcg
HOM Female postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response UC Davis | IMPC 2.19E-5
Fshr
Fshrtm1(KOMP)Vlcg
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MARC | IMPC 8.68E-5
Phf3
Phf3em2(IMPC)Marc
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MARC | IMPC 8.68E-5
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Male postnatal absent startle reflex Combined SHIRPA and Dysmorphology | Startle response MRC Harwell | IMPC 8.71E-5

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