Phenotype: decreased pulmonary respiratory rate

Definition
fewer than the normal number of breaths per minute
Synonyms
reduced ventilation rate,  decreased respiratory rate,  decreased respiration rate,  reduced BF,  decreased breathing frequency,  reduced respiratory rate,  reduced respiration rate,  reduced pulmonary ventilation rate,  reduced breathing frequency,  bradypnea,  decreased pulmonary ventilation rate,  decreased ventilation rate,  decreased BF
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased pulmonary respiratory rate

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Lrrtm3
Lrrtm3tm1b(KOMP)Mbp
HOM Early adult decreased pulmonary respiratory rate 12.5 Mch Frequency of breathing
Challenge Whole Body Plethysmography
TCP
IMPC
2.97×10-07
Nudt19
Nudt19tm1.1(KOMP)Vlcg
HOM Early adult decreased pulmonary respiratory rate PBS Frequency of breathing
Challenge Whole Body Plethysmography
TCP
IMPC
6.23×10-06
Kcnj3
Kcnj3tm1.1(KOMP)Vlcg
HOM Early adult decreased pulmonary respiratory rate 12.5 Mch Frequency of breathing
Challenge Whole Body Plethysmography
TCP
IMPC
1.56×10-05
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM Early adult decreased pulmonary respiratory rate Respiration Rate
Echo
MRC Harwell
IMPC
2.22×10-05
Arap1
Arap1tm1b(EUCOMM)Wtsi
HOM Early adult decreased pulmonary respiratory rate 12.5 Mch Frequency of breathing
Challenge Whole Body Plethysmography
TCP
IMPC
2.26×10-05
Pnck
Pncktm1b(KOMP)Wtsi
HEM Early adult decreased pulmonary respiratory rate 50 Mch Frequency of breathing
Challenge Whole Body Plethysmography
TCP
IMPC
4.62×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.48% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased pulmonary respiratory rate (6/1261)

0.08% females (1/1255) 0.50% males (5/1004)

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