Phenotype: increased circulating total protein level

Definition total serum protein level above the normal range

Synonyms
  • hyperproteinemia
  • hyperproteinemia
  • increased plasma total protein level
  • increased plasma total protein level
  • increased total protein level
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Phenotype associations stats

0.93% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased circulating total protein level (30/3229)

0.87% females (28/3214) 0.62% males (20/3205)

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Gene variants with increased circulating total protein level

Total number of significant genotype-phenotype associations: 48

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein WTSI | IMPC 2.01E-16
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein ICS | IMPC 1.2E-9
Gys2
Gys2tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein WTSI | MGP 2.51E-9
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein MRC Harwell | IMPC 7.71E-8
Hsd17b11
Hsd17b11tm1.1(KOMP)Vlcg
HOM Female postnatal increased circulating total protein level Clinical Chemistry | Total protein JAX | IMPC 8.12E-8
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein WTSI | IMPC 1.42E-7
Dcaf7
Dcaf7tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein ICS | IMPC 5.44E-7
Rab5c
Rab5ctm1a(EUCOMM)Wtsi
HET Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein WTSI | IMPC 5.64E-7
Aqp1
Aqp1tm1b(EUCOMM)Wtsi
HOM Female postnatal increased circulating total protein level Clinical Chemistry | Total protein MRC Harwell | IMPC 1.11E-6
Kptn
Kptntm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein WTSI | EuroPhenome 1.29E-6
Gse1
Gse1tm1a(EUCOMM)Wtsi
HET Female postnatal increased circulating total protein level Clinical Chemistry | Total protein MRC Harwell | MGP 1.29E-6
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Female postnatal increased circulating total protein level Clinical Chemistry | Total protein HMGU | EuroPhenome 1.31E-6
Casq1
Casq1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein ICS | IMPC 1.32E-6
Sirt4
Sirt4tm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating total protein level Clinical Chemistry | Total protein MRC Harwell | IMPC 1.49E-6
Aqp3
Aqp3tm2b(EUCOMM)Wtsi
HOM Female postnatal increased circulating total protein level Clinical Chemistry | Total protein MRC Harwell | IMPC 2.84E-6
Pax4
Pax4tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein ICS | IMPC 5.21E-6
Fndc7
Fndc7tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein UC Davis | IMPC 5.58E-6
Fam20c
Fam20ctm1b(KOMP)Wtsi
HET Female postnatal increased circulating total protein level Clinical Chemistry | Total protein UC Davis | IMPC 1.46E-5
Cacybp
Cacybptm1b(EUCOMM)Wtsi
HET Female postnatal increased circulating total protein level Clinical Chemistry | Total protein UC Davis | IMPC 1.78E-5
Prss27
Prss27tm1.1(NCOM)Mfgc
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein TCP | IMPC 1.91E-5
Skida1
Skida1tm1.1(KOMP)Wtsi
HET Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein TCP | IMPC 2.08E-5
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Female postnatal increased circulating total protein level Clinical Chemistry | Total protein MRC Harwell | IMPC 3.08E-5
Derl2
Derl2tm1b(EUCOMM)Hmgu
HET Female postnatal increased circulating total protein level Clinical Chemistry | Total protein ICS | IMPC 3.34E-5
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein WTSI | IMPC 3.39E-5
Tm9sf4
Tm9sf4tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein WTSI | IMPC 4.35E-5
Dbil5
Dbil5tm1(KOMP)Wtsi
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein MARC | IMPC 6.11E-5
Avp
Avptm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating total protein level Clinical Chemistry | Total protein MRC Harwell | IMPC 7.83E-5
BC030499
BC030499tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein JAX | IMPC 9.0E-5
Capn12
Capn12tm1b(EUCOMM)Hmgu
HOM Female postnatal increased circulating total protein level Clinical Chemistry | Total protein HMGU | IMPC 9.25E-5
Esr2
Esr2em1Marc
HOM Female Male postnatal increased circulating total protein level Clinical Chemistry | Total protein MARC | IMPC 9.87E-5

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