Phenotype: increased hemoglobin content

Phenotype associations stats

1.37% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased hemoglobin content (47/3443)

1.17% females (40/3423) 1.28% males (44/3438)

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Gene variants with increased hemoglobin content

Total number of significant genotype-phenotype associations: 88

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Tppp
Tppptm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 2.6E-12
Hdac1
Hdac1tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration HMGU | EuroPhenome 4.98E-12
Ankrd13a
Ankrd13aGt(RRH308)Byg
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration WTSI | EuroPhenome 8.94E-11
Hfe2
Hfe2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 3.29E-10
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.63E-9
Cops4
Cops4tm1a(EUCOMM)Hmgu
HET Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 1.89E-9
Cfb
Cfbtm1.1(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 2.48E-9
Rft1
Rft1tm1b(KOMP)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.02E-8
Phkg2
Phkg2tm1.1(KOMP)Vlcg
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 1.17E-8
Bag1
Bag1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 7.96E-8
Smarcal1
Smarcal1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 1.27E-7
Ptpn2
Ptpn2tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 1.48E-7
Pik3cb
Pik3cbtm1a(EUCOMM)Wtsi
HET Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 2.92E-7
Txnip
Txniptm1b(EUCOMM)Hmgu
HOM Female postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 5.28E-7
Cyb561
Cyb561tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 6.25E-7
Ydjc
Ydjctm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 7.03E-7
Myh1
Myh1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 1.23E-6
Ltbp1
Ltbp1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 1.27E-6
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.49E-6
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 2.62E-6
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration WTSI | EuroPhenome 2.81E-6
Mir203
Mir203tm1(mirKO)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MARC | IMPC 5.75E-6
Jup
Juptm1.1(KOMP)Vlcg
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 7.36E-6
Pik3cb
Pik3cbtm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 7.57E-6
Fbxo43
Fbxo43em1Marc
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MARC | IMPC 8.08E-6
Esr2
Esr2em1Marc
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MARC | IMPC 8.83E-6
Gbx1
Gbx1
HOM Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 1.03E-5
Ahrr
Ahrrtm1b(KOMP)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 1.18E-5
Rab36
Rab36tm1b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 1.35E-5
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.43E-5
Slc30a8
Slc30a8tm1a(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 1.46E-5
Crlf3
Crlf3tm1a(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration WTSI | EuroPhenome 1.63E-5
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Female postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.8E-5
Espn
Espntm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 2.17E-5
Mindy1
Mindy1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 3.27E-5
Gprc6a
Gprc6atm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 3.5E-5
Atl2
Atl2tm2b(EUCOMM)Hmgu
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 3.82E-5
Rxfp2
Rxfp2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin HMGU | IMPC 4.09E-5
Calcoco2
Calcoco2tm1(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 4.82E-5
Angel1
Angel1tm1(NCOM)Cmhd
HOM Female Male postnatal increased hemoglobin content Haematology | Haemoglobin CMHD | EuroPhenome 6.03E-5
Bbc3
Bbc3em1Marc
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MARC | IMPC 6.28E-5
D930020B18Rik
D930020B18Riktm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 6.32E-5
Chn1
Chn1tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 6.49E-5
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Female postnatal increased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 6.94E-5
Zfp536
Zfp536tm1.1(KOMP)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 7.32E-5
Nr1d2
Nr1d2tm1Dgen
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 7.76E-5
Gpr183
Gpr183tm1.1(KOMP)Vlcg
HOM Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 8.18E-5
Ahrr
Ahrrtm1b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 8.3E-5
Eme1
Eme1tm1.1(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin BCM | IMPC 8.75E-5

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