Phenotype: increased hemoglobin content

Definition increase in the total hemoglobin content in the circulating blood

Synonyms increased haemoglobin content
Related
Synonyms
hemoglobinemia

MP browserMP:0005564

Phenotype associations stats

1.48% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased hemoglobin content (61/4109)

1.25% females (51/4084) 1.35% males (55/4084)

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Gene variants with increased hemoglobin content

Total number of significant genotype-phenotype associations: 106

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Tppp
Tppptm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 5.05E-11
Ankrd13a
Ankrd13aGt(RRH308)Byg
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration WTSI | EuroPhenome 8.94E-11
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.63E-9
Cops4
Cops4tm1a(EUCOMM)Hmgu
HET Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 1.89E-9
Hfe2
Hfe2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 2.04E-9
Fam163a
Fam163atm2b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 3.9E-9
Ydjc
Ydjctm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 1.05E-8
Entpd1
Entpd1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 2.75E-8
Bag1
Bag1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 7.96E-8
Nfya
NfyaGt(EUCJ0004f10)Hmgu
HET Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 9.03E-8
Casq1
Casq1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin ICS | IMPC 1.1E-7
Cfb
Cfbtm1.1(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 2.05E-7
Smarcal1
Smarcal1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 3.0E-7
Txnip
Txniptm1b(EUCOMM)Hmgu
HOM Female postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 5.28E-7
Nsf
Nsftm1b(KOMP)Mbp
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 5.83E-7
Rft1
Rft1tm1b(KOMP)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 9.32E-7
Eme1
Eme1tm1.1(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin BCM | IMPC 1.18E-6
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.48E-6
Bmp10
Bmp10tm3b(EUCOMM)Hmgu
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin ICS | IMPC 1.86E-6
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration WTSI | EuroPhenome 2.81E-6
Ptpn2
Ptpn2tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 3.07E-6
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 4.19E-6
Grin1
Grin1tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 5.02E-6
Fbxo43
Fbxo43em1(IMPC)Marc
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MARC | IMPC 6.6E-6
Myo1h
Myo1htm1b(KOMP)Wtsi
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 6.76E-6
Gys2
Gys2tm1a(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology | Haemoglobin WTSI | EuroPhenome 7.46E-6
Prom2
Prom2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 7.54E-6
Thada
Thadatm1b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin BCM | IMPC 8.86E-6
Tmem161b
Tmem161btm2b(EUCOMM)Hmgu
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 9.27E-6
Mir203
Mir203tm1(mirKO)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MARC | IMPC 9.77E-6
Ahrr
Ahrrtm1b(KOMP)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 9.96E-6
Gbx1
Gbx1
HOM Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 1.03E-5
Dnmt3a
Dnmt3atm1b(KOMP)Wtsi
HET Female postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 1.08E-5
Adcy3
Adcy3tm1a(EUCOMM)Wtsi
HET Female postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 1.38E-5
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.39E-5
Atl2
Atl2tm2b(EUCOMM)Hmgu
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.48E-5
Afm
Afmtm1a(KOMP)Wtsi
HOM Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 1.65E-5
Gprc6a
Gprc6atm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 1.79E-5
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Female postnatal increased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.8E-5
Dock10
Dock10tm1a(EUCOMM)Hmgu
HOM Male postnatal increased hemoglobin content Haematology | Haemoglobin HMGU | EuroPhenome 2.03E-5
Esr2
Esr2em1(IMPC)Marc
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin MARC | IMPC 2.24E-5
Rab36
Rab36tm1b(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 2.43E-5
Ltbp1
Ltbp1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 2.53E-5
Fpr3
Fpr3tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin ICS | IMPC 2.6E-5
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 2.62E-5
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 2.96E-5
Mindy1
Mindy1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 3.27E-5
Jup
Juptm1.1(KOMP)Vlcg
HET Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 3.77E-5
Gyg
Gygtm1b(KOMP)Wtsi
HET Female Male postnatal increased hemoglobin content Hematology | Hemoglobin BCM | IMPC 3.85E-5
D930020B18Rik
D930020B18Riktm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 3.96E-5
Nr1h3
Nr1h3tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 4.64E-5
Spns2
Spns2tm1a(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 4.93E-5
Fkbp10
Fkbp10tm2a(EUCOMM)Wtsi
HET Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 5.23E-5
Calcoco2
Calcoco2tm1(KOMP)Wtsi
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 5.38E-5
Cntn6
Cntn6em1(IMPC)Wtsi
HOM Female postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 5.99E-5
Angel1
Angel1tm1(NCOM)Cmhd
HOM Female Male postnatal increased hemoglobin content Haematology | Haemoglobin CMHD | EuroPhenome 6.03E-5
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Female postnatal increased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 6.94E-5
Macrod2
Macrod2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin JAX | IMPC 6.99E-5
Nr1d2
Nr1d2tm1Dgen
HOM Female Male postnatal increased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 7.76E-5
Tnfrsf18
Tnfrsf18tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 8.62E-5
Cpgi13569
Cpgi13569tm1.1(NCC)WCS
HOM Female Male postnatal increased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 9.55E-5

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