Phenotype: increased mean corpuscular hemoglobin

Definition greater than the average levels of hemoglobin contained in an erythrocyte

Synonyms
  • high MCH
  • high MCH
  • increased mean corpuscular haemoglobin
  • increased mean corpuscular haemoglobin
  • hyperchromia
  • increased MCH
  • high mean corpuscular haemoglobin
  • high mean corpuscular hemoglobin
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MP browserMP:0005561

Phenotype associations stats

2.66% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased mean corpuscular hemoglobin (101/3804)

2.36% females (89/3773) 2.46% males (93/3775)

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Gene variants with increased mean corpuscular hemoglobin

Total number of significant genotype-phenotype associations: 184

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Foxo3
Foxo3tm1.1(KOMP)Vlcg
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 0.0
Hjv
Hjvtm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 0.0
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 3.43E-37
Knstrn
Knstrntm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin ICS | IMPC 5.71E-31
Fam53b
Fam53btm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin HMGU | IMPC 3.15E-25
Thsd1
Thsd1tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.35E-15
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 2.22E-13
Tfr2
Tfr2em1(IMPC)Rbrc
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin RBRC | IMPC 7.58E-13
Rab43
Rab43tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 9.25E-13
Prdm2
Prdm2em1(IMPC)Marc
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MARC | IMPC 2.6E-12
Bhlhe40
Bhlhe40tm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 2.7E-12
Dcaf10
Dcaf10tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 6.33E-12
Trim8
Trim8em1(IMPC)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 2.68E-11
Ppp1cc
Ppp1ccem1(IMPC)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 4.98E-11
Ube2j2
Ube2j2em1(IMPC)Rbrc
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin RBRC | IMPC 5.5E-11
Zzef1
Zzef1tm2.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 8.54E-11
Pak2
Pak2em1(IMPC)H
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MRC Harwell | IMPC 2.11E-10
Cpa1
Cpa1em1(IMPC)Marc
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MARC | IMPC 4.41E-10
2310057J18Rik
2310057J18Riktm1a(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 4.8E-10
Chn1
Chn1tm1.1(KOMP)Vlcg
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 8.52E-10
Fam160a1
Fam160a1tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 7.26E-9
Phf5a
Phf5aem2(IMPC)Marc
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MARC | IMPC 9.97E-9
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 1.1E-8
Tbc1d4
Tbc1d4tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.18E-8
Cfh
Cfhtm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 1.29E-8
Acsf2
Acsf2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.73E-8
Vangl1
Vangl1tm1e(KOMP)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 2.38E-8
Brcc3
Brcc3em1(IMPC)Marc
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MARC | IMPC 3.05E-8
Bnip2
Bnip2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 3.7E-8
Eml1
Eml1em1(IMPC)Wtsi
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 4.51E-8
Copg1
Copg1tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 4.8E-8
Cr1l
Cr1ltm1b(KOMP)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 6.27E-8
Fbxw13
Fbxw13em2(IMPC)Marc
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MARC | IMPC 6.7E-8
Bbc3
Bbc3em1(IMPC)Marc
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MARC | IMPC 7.73E-8
Mfsd2b
Mfsd2btm1a(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 9.13E-8
Rab3ip
Rab3iptm1.1(KOMP)Vlcg
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.0E-7
Cd33
Cd33tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.16E-7
Lsm11
Lsm11tm1a(KOMP)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 1.38E-7
Prpf6
Prpf6tm1.1(KOMP)Vlcg
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 2.3E-7
Fbxl2
Fbxl2em2(IMPC)Marc
HOM Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MARC | IMPC 2.32E-7
Mad2l2
Mad2l2tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 2.7E-7
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 4.02E-7
Mst1
Mst1tm1(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 4.8E-7
Abca4
Abca4tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 7.22E-7
Slc6a14
Slc6a14tm1b(KOMP)Wtsi
HOM Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin UC Davis | IMPC 9.51E-7
Ripply3
Ripply3tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 9.72E-7
Lmnb1
Lmnb1tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 1.03E-6
Brd2
Brd2em1(IMPC)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 1.11E-6
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 2.11E-6
Nutm1
Nutm1tm1b(KOMP)Wtsi
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 2.52E-6
Slc35f6
Slc35f6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 2.62E-6
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 2.67E-6
Arrb1
Arrb1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 2.72E-6
Mylip
Myliptm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 3.31E-6
Mtor
Mtortm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 3.82E-6
Elmo1
Elmo1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 3.99E-6
Ptges2
Ptges2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 7.72E-6
Pitpnm1
Pitpnm1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 8.67E-6
Osm
Osmtm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.14E-5
Ahrr
Ahrrtm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.26E-5
Ahrr
Ahrrtm1b(KOMP)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.3E-5
Skida1
Skida1tm1(KOMP)Wtsi
HET Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 1.37E-5
Arhgap25
Arhgap25tm1a(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 1.42E-5
Tmem136
Tmem136tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.63E-5
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MRC Harwell | IMPC 1.66E-5
Tbx22
Tbx22tm1.1(KOMP)Vlcg
HOM Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 1.76E-5
Lpar6
Lpar6tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 2.03E-5
Piezo1
Piezo1tm1b(KOMP)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin UC Davis | IMPC 2.11E-5
Cdh23
Cdh23tm2b(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 2.13E-5
D930020B18Rik
D930020B18Riktm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin UC Davis | IMPC 2.14E-5
Aurka
Aurkatm1b(EUCOMM)Hmgu
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 2.18E-5
Slc4a10
Slc4a10tm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin MRC Harwell | IMPC 2.42E-5
Reg3d
Reg3dtm1b(EUCOMM)Wtsi
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 2.8E-5
Stag3
Stag3tm1e.1(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 2.85E-5
Havcr2
Havcr2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin UC Davis | IMPC 2.95E-5
Anp32e
Anp32etm1e(KOMP)Wtsi
HOM Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 3.0E-5
Tmem18
Tmem18tm1b(EUCOMM)Wtsi
HOM Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 3.0E-5
Ltbp1
Ltbp1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 4.09E-5
Rfc1
Rfc1tm1b(KOMP)Mbp
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 4.25E-5
H2-M5
H2-M5tm1(KOMP)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 4.27E-5
Slc25a28
Slc25a28tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 4.39E-5
Pnpt1
Pnpt1tm1a(KOMP)Wtsi
HET Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 4.44E-5
Trim66
Trim66tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 4.56E-5
Apbb2
Apbb2tm1.1(KOMP)Vlcg
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin UC Davis | IMPC 4.58E-5
Arpc2
Arpc2tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 5.6E-5
Usp33
Usp33tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 5.72E-5
Usp11
Usp11tm1(KOMP)Wtsi
HOM Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 5.88E-5
Itsn2
Itsn2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin UC Davis | IMPC 6.03E-5
Mmachc
Mmachctm1.1(NCOM)Mfgc
HET Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin TCP | IMPC 6.19E-5
Rdx
Rdxtm1.1(KOMP)Vlcg
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 6.6E-5
Vps33b
Vps33btm1a(EUCOMM)Wtsi
HET Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 7.0E-5
Bclaf1
Bclaf1tm1b(EUCOMM)Wtsi
HET Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 7.43E-5
Morc2a
Morc2aem1(IMPC)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 7.49E-5
S100b
S100btm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | EuroPhenome 7.81E-5
Palb2
Palb2tm1.1(KOMP)Vlcg
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin JAX | IMPC 8.09E-5
Trf
Trfem1(IMPC)Rbrc
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin RBRC | IMPC 8.18E-5
Med22
Med22tm1a(EUCOMM)Wtsi
HET Female postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin WTSI | IMPC 8.9E-5
Angptl1
Angptl1tm4b(KOMP)Wtsi
HOM Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin KMPC | IMPC 9.48E-5
Ezh2
Ezh2tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 9.6E-5
Espn
Espntm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 9.65E-5
Sarnp
Sarnptm1b(EUCOMM)Hmgu
HET Female Male postnatal increased mean corpuscular hemoglobin Hematology | Mean corpuscular hemoglobin HMGU | IMPC 9.74E-5
Sar1b
Sar1btm1a(EUCOMM)Wtsi
HET Female Male postnatal increased mean corpuscular hemoglobin Haematology test | Mean-corpuscular-haemoglobin WTSI | MGP 9.9E-5

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