Definition
less than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction
Synonyms
reduced circulating creatinine level
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased circulating creatinine level
Total number of significant genotype-phenotype associations: 95
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Ap4e1 Ap4e1tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI MGP |
2.62×10-18 | |
| Rhbdf2 Rhbdf2Rhbdf2 |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell EuroPhenome |
8.49×10-15 | |
| Phykpl Phykpltm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS EuroPhenome |
5.63×10-13 | |
| Tex2 Tex2em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
5.10×10-11 | |
| Tbr1 Tbr1tm1.1(KOMP)Mbp |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
7.43×10-10 | |
| Exph5 Exph5tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
9.81×10-09 | |
| Cxxc4 Cxxc4em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
1.09×10-08 | |
| Cspp1 Cspp1em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
1.75×10-08 | |
| B3galt1 B3galt1em1(IMPC)Marc |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MARC IMPC |
6.38×10-08 | |
| Srprb Srprbtm2b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
2.05×10-07 | |
| Bmp10 Bmp10tm3b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
2.55×10-07 | |
| Casq1 Casq1tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
2.58×10-07 | |
| Efr3b Efr3bem1(IMPC)Mbp |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
2.96×10-07 | |
| Frey1 Frey1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
5.11×10-07 | |
| Taco1 Taco1em1(IMPC)J |
HOM | Late adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
5.16×10-07 | |
| Mab21l4 Mab21l4tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI MGP |
5.17×10-07 | |
| Selenbp1 Selenbp1tm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
5.64×10-07 | |
| Micos13 Micos13tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
5.87×10-07 | |
| Hip1 Hip1em1(IMPC)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
9.93×10-07 | |
| Trank1 Trank1em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
1.89×10-06 | |
| Zfp692 Zfp692em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
2.24×10-06 | |
| Zfp612 Zfp612em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
2.45×10-06 | |
| Pank4 Pank4em1(IMPC)Kmpc |
HOM | Late adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
KMPC IMPC |
2.83×10-06 | |
| Pik3cb Pik3cbtm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI MGP |
3.43×10-06 | |
| Ap2a1 Ap2a1em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
3.54×10-06 | |
| Pawr Pawrtm1b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
3.55×10-06 | |
| Stk26 Stk26tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
CCP-IMG IMPC |
3.64×10-06 | |
| Adss2 Adss2tm1b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
4.47×10-06 | |
| Trub1 Trub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
4.48×10-06 | |
| Mrps18c Mrps18ctm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
6.30×10-06 | |
| Dgkh Dgkhem1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
7.14×10-06 | |
| Mr1 Mr1em1(IMPC)H |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
8.22×10-06 | |
| Slc16a2 Slc16a2tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI MGP |
9.97×10-06 | |
| Cxcr4 Cxcr4em1(IMPC)Mbp |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
1.04×10-05 | |
| Dhfr Dhfrtm1b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
TCP IMPC |
1.07×10-05 | |
| Spatc1l Spatc1lem1(IMPC)H |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
1.21×10-05 | |
| Nedd4 Nedd4tm2b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
1.26×10-05 | |
| Pdpr Pdprtm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
1.26×10-05 | |
| Myo10 Myo10tm2(KOMP)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI IMPC |
1.30×10-05 | |
| Cyria Cyriaem1(IMPC)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
1.58×10-05 | |
| Zfp503 Zfp503em1(IMPC)Mbp |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
1.73×10-05 | |
| Usp38 Usp38tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
1.75×10-05 | |
| Myoz1 Myoz1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
1.81×10-05 | |
| Galr1 Galr1em1(IMPC)H |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
1.94×10-05 | |
| Ly6g6d Ly6g6dtm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
2.23×10-05 | |
| Eomes Eomestm1b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
2.40×10-05 | |
| Abce1 Abce1tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
2.48×10-05 | |
| Rab4a Rab4atm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
2.48×10-05 | |
| Fgd3 Fgd3em1(IMPC)Ccpcz |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
CCP-IMG IMPC |
2.71×10-05 | |
| Cmtr2 Cmtr2tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
2.91×10-05 | |
| Fut4 Fut4em1(IMPC)Ics |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
2.99×10-05 | |
| Rab18 Rab18Gt(EUCE0233a03)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell EuroPhenome |
3.36×10-05 | |
| Arl5c Arl5ctm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
3.44×10-05 | |
| Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
3.75×10-05 | |
| Asb1 Asb1em1(IMPC)Ccpcz |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
CCP-IMG IMPC |
3.78×10-05 | |
| 2610318N02Rik 2610318N02Riktm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI IMPC |
3.80×10-05 | |
| Trmt10a Trmt10atm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI MGP |
3.85×10-05 | |
| Mtpap Mtpaptm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
4.05×10-05 | |
| Ehmt1 Ehmt1tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MARC IMPC |
4.09×10-05 | |
| Gorasp1 Gorasp1tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
4.48×10-05 | |
| Cox19 Cox19tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
TCP IMPC |
4.52×10-05 | |
| Fam185a Fam185aem1(IMPC)Ccpcz |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
CCP-IMG IMPC |
4.56×10-05 | |
| Ckb Ckbtm1.1(KOMP)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
4.60×10-05 | |
| Dusp3 Dusp3tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI EuroPhenome |
4.68×10-05 | |
| Flot2 Flot2tm2e(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS EuroPhenome |
4.68×10-05 | |
| Psip1 Psip1em1(IMPC)J |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
4.92×10-05 | |
| Mab21l2 Mab21l2em1(IMPC)Mbp |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
5.00×10-05 | |
| Sh2d5 Sh2d5tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI IMPC |
5.06×10-05 | |
| Dgke Dgkeem1(IMPC)Tcp |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
TCP IMPC |
5.11×10-05 | |
| Gpcpd1 Gpcpd1em1(IMPC)Tcp |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
TCP IMPC |
5.91×10-05 | |
| Rev3l Rev3ltm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
6.36×10-05 | |
| Eprs1 Eprs1tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
TCP IMPC |
6.37×10-05 | |
| F10 F10tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell IMPC |
6.55×10-05 | |
| Zfp558 Zfp558em1(IMPC)Mbp |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
6.78×10-05 | |
| Ints10 Ints10tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
6.79×10-05 | |
| Prkcz Prkcztm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI EuroPhenome |
7.10×10-05 | |
| Cisd2 Cisd2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
MRC Harwell EuroPhenome |
7.26×10-05 | |
| Tmod3 Tmod3tm1a(EUCOMM)Hmgu |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS EuroPhenome |
7.32×10-05 | |
| Hoxa2 Hoxa2tm1b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
7.73×10-05 | |
| Pbrm1 Pbrm1tm1b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
7.74×10-05 | |
| Mrps22 Mrps22tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
7.81×10-05 | |
| Trap1 Trap1em1(IMPC)Mbp |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
UC Davis IMPC |
7.95×10-05 | |
| Hmgn1 Hmgn1em1(IMPC)Ics |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
8.20×10-05 | |
| Cstb Cstbtm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
ICS IMPC |
8.46×10-05 | |
| Dbndd2 Dbndd2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
TCP IMPC |
8.52×10-05 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
WTSI IMPC |
8.56×10-05 | |
| Wscd2 Wscd2em1(IMPC)J |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
9.06×10-05 | |
| Orc6 Orc6em1(IMPC)J |
HET | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
JAX IMPC |
9.20×10-05 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating creatinine level | Creatinine Clinical Chemistry |
HMGU IMPC |
9.28×10-05 |