Phenotype: decreased cornea thickness

Definition
decreased thickness of the cornea, the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure
Synonyms
corneal thinning,  decreased corneal thickness,  decreased tunica cornea thickness,  thin cornea
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased cornea thickness

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Tead1
Tead1tm1b(KOMP)Wtsi
HET Early adult decreased cornea thickness Left corneal thickness
Eye Morphology
BCM
IMPC
2.64×10-08
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM   Early adult decreased cornea thickness Right corneal thickness
Eye Morphology
ICS
IMPC
5.28×10-07
Zfp90
Zfp90em1(IMPC)Bay
HET Early adult decreased cornea thickness Right corneal thickness
Eye Morphology
BCM
IMPC
3.68×10-06
Fem1c
Fem1cem1(IMPC)Bay
HOM Early adult decreased cornea thickness Right corneal thickness
Eye Morphology
BCM
IMPC
1.50×10-05
9930012K11Rik
9930012K11Riktm2b(EUCOMM)Hmgu
HOM   Early adult decreased cornea thickness Left corneal thickness
Eye Morphology
BCM
IMPC
2.29×10-05
Tead1
Tead1tm1a(KOMP)Wtsi
HET Early adult decreased cornea thickness Right corneal thickness
Eye Morphology
BCM
IMPC
2.93×10-05
Dsg2
Dsg2tm1b(EUCOMM)Wtsi
HOM Early adult decreased cornea thickness Left corneal thickness
Eye Morphology
BCM
IMPC
3.64×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Eye Morphology

 Phenotype associations stats

0.77% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased cornea thickness (6/776)

0.48% females (4/832) 0.12% males (1/826)

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