Definition
greater than the normal blood concentration of the major hormone derived from the thyroid gland that normally affects cellular metabolism
Synonyms
increased circulating level of T4,
increased circulating level of thyroxin,
increased circulating level of thyroxine
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased circulating thyroxine level
Total number of significant genotype-phenotype associations: 7
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Skida1 Skida1tm1(KOMP)Wtsi |
HET | Early adult | increased circulating thyroxine level | Thyroxine Clinical Chemistry |
WTSI IMPC |
3.20×10-07 | |
| Zmynd11 Zmynd11em1(IMPC)Wtsi |
HET | Early adult | increased circulating thyroxine level | Thyroxine Clinical Chemistry |
WTSI IMPC |
9.30×10-06 | |
| Ddx42 Ddx42tm1b(EUCOMM)Wtsi |
HET | Early adult | increased circulating thyroxine level | Thyroxine Clinical Chemistry |
WTSI IMPC |
1.71×10-05 | |
| Ahcyl1 Ahcyl1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating thyroxine level | Thyroxine Clinical Chemistry |
WTSI IMPC |
1.95×10-05 | |
| Camsap3 Camsap3tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating thyroxine level | Thyroxine Clinical Chemistry |
WTSI IMPC |
3.01×10-05 | |
| Dhx33 Dhx33tm1b(KOMP)Wtsi |
HET | Early adult | increased circulating thyroxine level | Thyroxine Clinical Chemistry |
WTSI IMPC |
4.69×10-05 | |
| Mlec Mlectm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating thyroxine level | Thyroxine Clinical Chemistry |
WTSI IMPC |
5.30×10-05 |