Phenotype: improved glucose tolerance

Definition
better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals
Synonyms
increased glucose tolerance
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with improved glucose tolerance

Total number of significant genotype-phenotype associations: 143

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Atp13a3
Atp13a3em1(IMPC)J
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.45×10-20
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Late adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.93×10-17
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
6.04×10-15
Gcgr
Gcgrtm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.71×10-14
Trim37
Trim37em1(IMPC)Marc
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MARC
IMPC
1.09×10-13
Klhl32
Klhl32em1(IMPC)J
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.63×10-13
Cdc20
Cdc20tm1.1(KOMP)Vlcg
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.08×10-13
Ush1c
Ush1ctm1a(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
4.37×10-13
D630045J12Rik
D630045J12Riktm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
2.08×10-12
Sytl4
Sytl4em1(IMPC)Hmgu
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
1.26×10-11
Notch3
Notch3tm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.66×10-11
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
1.98×10-11
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
2.14×10-11
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.38×10-10
Pdp1
Pdp1em1(IMPC)Mbp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
4.94×10-10
Pdpr
Pdprtm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
5.73×10-10
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
6.26×10-10
Ubr7
Ubr7em1(IMPC)Tcp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
3.60×10-09
Abhd17a
Abhd17atm1a(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
1.30×10-08
Adra2a
Adra2atm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.63×10-08
Aasdhppt
Aasdhppttm1.1(KOMP)Vlcg
HET Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.57×10-08
Bmp10
Bmp10tm3b(EUCOMM)Hmgu
HET Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
5.61×10-08
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
1.39×10-07
Rabgap1
Rabgap1tm1b(EUCOMM)Hmgu
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
1.55×10-07
Cnot3
Cnot3em1(IMPC)Rbrc
HET   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
RBRC
IMPC
1.91×10-07
Fam163a
Fam163atm2b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.08×10-07
Dact3
Dact3tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.24×10-07
Focad
Focadem1(IMPC)Bay
HET Late adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
2.82×10-07
Naa10
Naa10em1(IMPC)Mbp
HOM Late adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.07×10-07
Lrrc15
Lrrc15tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.35×10-07
Rab11a
Rab11atm1b(KOMP)Wtsi
HET Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
6.71×10-07
Ifnar1
Ifnar1tm2a(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
1.16×10-06
Nfat5
Nfat5tm1b(KOMP)Wtsi
HET   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.17×10-06
Arhgap17
Arhgap17tm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
1.20×10-06
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MARC
IMPC
1.21×10-06
Bves
Bvestm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.21×10-06
Dennd5b
Dennd5bem1(IMPC)Tcp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
1.25×10-06
Abcd3
Abcd3em1(IMPC)J
HOM Late adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.34×10-06
Atp5po
Atp5potm1.1(KOMP)Vlcg
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.53×10-06
H1f8
H1f8tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.57×10-06
Tmem116
Tmem116tm1b(EUCOMM)Hmgu
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
2.10×10-06
Slitrk1
Slitrk1tm1.1(KOMP)Vlcg
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.24×10-06
Cibar1
Cibar1tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.56×10-06
Lmna
Lmnatm1b(EUCOMM)Wtsi
HET Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
2.85×10-06
Irgm1
Irgm1em1(IMPC)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
3.11×10-06
Peli1
Peli1tm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.15×10-06
Il10ra
Il10ratm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
3.89×10-06
Sytl4
Sytl4em1(IMPC)Hmgu
HEM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
3.94×10-06
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
4.53×10-06
Zer1
Zer1em1(IMPC)J
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
5.22×10-06
Slc1a4
Slc1a4tm1e(KOMP)Wtsi
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
5.28×10-06
Ccl26
Ccl26tm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
5.36×10-06
Pdlim4
Pdlim4em1(IMPC)Ics
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
5.69×10-06
Acbd5
Acbd5tm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
5.98×10-06
Tuft1
Tuft1tm1a(KOMP)Wtsi
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
6.05×10-06
Dpp4
Dpp4tm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
6.07×10-06
4933402J07Rik
4933402J07Rikem1(IMPC)J
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
6.67×10-06
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
6.80×10-06
Mpdz
Mpdzem1(IMPC)J
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
7.12×10-06
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET   Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
7.19×10-06
Gal3st1
Gal3st1em1(IMPC)Rbrc
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
RBRC
IMPC
7.29×10-06
Usp15
Usp15em1(IMPC)Marc
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MARC
IMPC
7.38×10-06
Adgra1
Adgra1tm1b(EUCOMM)Hmgu
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
7.79×10-06
Thra
Thratm1b(EUCOMM)Wtsi
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
7.93×10-06
Dnajc30
Dnajc30tm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
8.93×10-06
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
9.64×10-06
Dcun1d3
Dcun1d3em1(IMPC)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
1.02×10-05
Tg
Tgem1(IMPC)J
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.07×10-05
Tmprss2
Tmprss2tm2b(EUCOMM)Hmgu
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
1.14×10-05
Mgme1
Mgme1em1(IMPC)J
HOM Late adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.23×10-05
Camk2b
Camk2btm1b(EUCOMM)Hmgu
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
1.36×10-05
Pskh1
Pskh1tm1b(EUCOMM)Wtsi
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.54×10-05
Abhd14a
Abhd14atm2a(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
1.58×10-05
Hnrnpc
Hnrnpctm1b(EUCOMM)Hmgu
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.72×10-05
Septin5
Septin5tm1b(EUCOMM)Hmgu
HET   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
RBRC
IMPC
1.74×10-05
Setx
Setxtm1b(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
1.85×10-05
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
2.23×10-05
Ptprd
Ptprdtm2a(KOMP)Wtsi
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.25×10-05
Ap2a1
Ap2a1em1(IMPC)J
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
2.31×10-05
Vapb
Vapbem1(IMPC)H
HOM Late adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.48×10-05
Acoxl
Acoxlem1(IMPC)Mbp
HOM Late adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.55×10-05
Ctif
Ctifem1(IMPC)J
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
2.57×10-05
Mtnr1b
Mtnr1btm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.62×10-05
Me1
Me1em1(IMPC)Tcp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
2.71×10-05
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
2.71×10-05
Zfp422
Zfp422em1(IMPC)J
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.09×10-05
Stx16
Stx16tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.22×10-05
Ehf
Ehfem1(IMPC)Kmpc
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
KMPC
IMPC
3.60×10-05
Syce1
Syce1tm1b(KOMP)Wtsi
HOM   Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.71×10-05
Akap13
Akap13em1(IMPC)Mbp
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.75×10-05
Fbxo30
Fbxo30tm1b(KOMP)Wtsi
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.87×10-05
Wdr11
Wdr11em1(IMPC)Mbp
HET Late adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.93×10-05
Cops7a
Cops7atm1b(KOMP)Mbp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.95×10-05
Pnmt
Pnmttm1.1(KOMP)Vlcg
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.99×10-05
Stmn4
Stmn4tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.23×10-05
Bola2
Bola2tm1(KOMP)Wtsi
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MARC
IMPC
4.26×10-05
Loricrin
Loricrintm1.1(KOMP)Vlcg
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
4.38×10-05
Pstpip2
Pstpip2em1(IMPC)Tcp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
4.40×10-05
Wdr6
Wdr6em1(IMPC)J
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.40×10-05
Prmt9
Prmt9em1(IMPC)J
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.46×10-05
Ahnak
Ahnaktm1b(KOMP)Mbp
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
4.56×10-05
Dspp
Dspptm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
4.57×10-05
Sdc1
Sdc1em1(IMPC)H
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
4.94×10-05
Atp1a3
Atp1a3tm1b(EUCOMM)Hmgu
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
5.51×10-05
Spice1
Spice1tm1b(EUCOMM)Hmgu
HOM   Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
5.51×10-05
Hnf4a
Hnf4atm1b(EUCOMM)Hmgu
HET Late adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
5.68×10-05
Rtbdn
Rtbdntm1a(EUCOMM)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
5.72×10-05
Tgm6
Tgm6tm1a(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
6.10×10-05
Osbpl11
Osbpl11tm1b(EUCOMM)Hmgu
HET Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
6.21×10-05
Pitpnc1
Pitpnc1em1(IMPC)Kmpc
HOM   Late adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
KMPC
IMPC
6.29×10-05
Krt8
Krt8tm1b(EUCOMM)Hmgu
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
6.37×10-05
Amt
Amtem1(IMPC)Tcp
HET Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
7.09×10-05
Tpo
Tpoem1(IMPC)H
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
7.19×10-05
Phf8
Phf8tm1dIcs
HEM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
7.25×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
7.41×10-05
Hoxa2
Hoxa2tm1b(EUCOMM)Wtsi
HET   Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
7.82×10-05
Rbl1
Rbl1tm1b(EUCOMM)Hmgu
HET   Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
7.99×10-05
Prg4
Prg4em1(IMPC)Ccpcz
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
8.37×10-05
Tgfb1i1
Tgfb1i1tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
8.50×10-05
Baat
Baatem1(IMPC)Mbp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
8.58×10-05
Fastk
Fastktm1.1(KOMP)Vlcg
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
8.74×10-05
Fads1
Fads1tm1.1(KOMP)Vlcg
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
8.98×10-05
Rbpj
Rbpjtm1b(EUCOMM)Hmgu
HET Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
9.19×10-05
Pfn1
Pfn1tm1a(EUCOMM)Wtsi
HET Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
9.32×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
9.41×10-05
Bscl2
Bscl2tm1b(EUCOMM)Hmgu
HOM Early adult improved glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
9.52×10-05
Adcy1
Adcy1tm1b(EUCOMM)Wtsi
HOM   Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
9.86×10-05
Inmt
Inmtem1(IMPC)Mbp
HOM Early adult improved glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
9.95×10-05

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 The way we measure

 Phenotype associations stats

1.77% of tested genes with null mutations on a B6N genetic background have a phenotype association to improved glucose tolerance (126/7120)

0.48% females (35/7342) 1.13% males (83/7352)

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