Phenotype: increased circulating cholesterol level

Definition greater than the normal amount in the blood of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues

Synonyms
  • high serum cholesterol level
  • high serum cholesterol level
  • increased total serum cholesterol level
  • increased total serum cholesterol level
  • increased total circulating cholesterol level
  • increased total plasma cholesterol level
  • elevated total circulating cholesterol level
  • elevated total plasma cholesterol level
  • elevated total serum cholesterol level
  • hypercholesterolemia
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Related
Synonyms
  • elevated VLDL cholesterol level
  • elevated VLDL cholesterol level
  • elevated circulating VLDL cholesterol level
  • elevated circulating VLDL cholesterol level
  • increased VLDL cholesterol level
  • increased circulating VLDL cholesterol level
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Phenotype associations stats

3.38% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased circulating cholesterol level (110/3257)

2.69% females (87/3240) 3.09% males (100/3240)

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Gene variants with increased circulating cholesterol level

Total number of significant genotype-phenotype associations: 296

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 0.0
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 0.0
Nr1h4
Nr1h4
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | EuroPhenome 1.57E-28
Ldlr
Ldlrtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 6.0E-24
Apoe
Apoetm1Unc
HOM Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 4.03E-21
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 1.62E-20
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 1.92E-19
Apoe
Apoetm1Unc
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 2.02E-19
Nr1h4
Nr1h4
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol ICS | EuroPhenome 2.57E-18
Tchp
Tchptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 9.48E-18
Rxrg
Rxrg
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol ICS | EuroPhenome 1.64E-16
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 2.74E-16
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 3.43E-16
Rxrg
Rxrg
HOM Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol ICS | EuroPhenome 6.76E-16
Reg3g
Reg3gtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 6.95E-16
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 1.14E-15
Ptpn23
Ptpn23tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 8.46E-14
Tchp
Tchptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.88E-12
Fbxo9
Fbxo9tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol TCP | IMPC 7.37E-12
Prdm13
Prdm13em2Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 1.47E-11
Notum
Notumem2Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 2.72E-11
Notum
Notumem2Tcp
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 2.72E-11
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MARC | IMPC 3.68E-11
Cyp7a1
Cyp7a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 4.23E-11
Ptpn23
Ptpn23tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 7.72E-11
Ldlr
Ldlrtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 1.56E-10
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HEM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 2.78E-10
Mrgprb2
Mrgprb2em2Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 2.82E-10
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 2.88E-10
Brd9
Brd9em1Tcp
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 3.69E-10
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 4.23E-10
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.41E-10
Usp47
Usp47tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MARC | IMPC 5.08E-10
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 6.23E-10
Reg3g
Reg3gtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 1.02E-9
Cep55
Cep55em2Tcp
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 1.17E-9
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.37E-9
Reg3g
Reg3gtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.73E-9
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.53E-9
Usp47
Usp47tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 3.07E-9
Hdac1
Hdac1tm1a(EUCOMM)Wtsi
HET Female postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol HMGU | EuroPhenome 4.17E-9
Arrb2
Arrb2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.44E-9
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 5.15E-9
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 7.81E-9
Hdac1
Hdac1tm1a(EUCOMM)Wtsi
HET Female postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol HMGU | EuroPhenome 8.79E-9
Spred3
Spred3em2Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 8.94E-9
Fgf10
Fgf10tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.04E-8
Fam207a
Fam207atm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 1.1E-8
Rexo2
Rexo2tm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.02E-8
Sirt6
Sirt6tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | MGP 2.12E-8
Cidec
Cidectm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | EuroPhenome 3.75E-8
Dntt
Dntttm2b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.02E-8
Fam207a
Fam207atm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 4.19E-8
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 8.62E-8
Btbd9
Btbd9tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 9.53E-8
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 9.63E-8
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.07E-7
Spred3
Spred3em2Tcp
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 1.36E-7
Celsr1
Celsr1Scy
HET Female postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 1.62E-7
Ntf5
Ntf5tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.63E-7
Ppil3
Ppil3tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 1.97E-7
Otud6a
Otud6atm1(KOMP)Vlcg
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 2.0E-7
Aspm
Aspmtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.59E-7
Ccnb1ip1
Ccnb1ip1em1Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 3.66E-7
Cyp7a1
Cyp7a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 4.11E-7
Rfc1
Rfc1tm1b(KOMP)Mbp
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.17E-7
Tm9sf4
Tm9sf4tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 4.68E-7
Prdm5
Prdm5em2Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 5.25E-7
Abcg2
Abcg2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 5.8E-7
Smyd2
Smyd2tm1a(KOMP)Wtsi
HOM Male postnatal increased circulating LDL cholesterol level Fasted Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 6.76E-7
Lrrc3
Lrrc3tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 7.37E-7
Ppil3
Ppil3tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 7.75E-7
Btbd9
Btbd9tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 7.9E-7
Ggps1
Ggps1tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 8.08E-7
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 9.74E-7
Gm648
Gm648tm1e(KOMP)Wtsi
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 1.0E-6
Yae1d1
Yae1d1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 1.16E-6
Hspa5
Hspa5tm1.1(KOMP)Vlcg
HET Female postnatal increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 1.19E-6
Gm648
Gm648tm1e(KOMP)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.25E-6
Prdm12
Prdm12tm2b(EUCOMM)Hmgu
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol TCP | IMPC 1.27E-6
Kansl1
Kansl1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.38E-6
Fbxo9
Fbxo9tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 1.45E-6
Kansl1
Kansl1tm1b(EUCOMM)Hmgu
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 1.61E-6
Aspm
Aspmtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.73E-6
Rexo2
Rexo2tm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 1.73E-6
Akt2
Akt2tm1Wcs
HOM Female postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 1.79E-6
Ntf5
Ntf5tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 1.92E-6
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol BCM | IMPC 3.48E-6
Tm9sf4
Tm9sf4tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 3.58E-6
Ifi44
Ifi44tm1b(KOMP)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 3.59E-6
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 3.96E-6
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.55E-6
Mllt6
Mllt6em1Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 4.72E-6
Cdca8
Cdca8tm1a(KOMP)Wtsi
HET Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 4.77E-6
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 4.92E-6
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 5.05E-6
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 5.42E-6
BC055324
BC055324tm1a(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 5.44E-6
Rnf10
Rnf10tm1a(KOMP)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 5.62E-6
Aqp1
Aqp1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 5.91E-6
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 6.1E-6
Nat8f2
Nat8f2tm1.1(KOMP)Vlcg
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 7.92E-6
Stk32a
Stk32atm1a(EUCOMM)Wtsi
HOM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 7.94E-6
Fndc7
Fndc7tm1.1(KOMP)Vlcg
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 8.09E-6
Slc24a4
Slc24a4tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 8.33E-6
Celsr1
Celsr1Scy
HET Female postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 9.44E-6
Slc24a4
Slc24a4tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 1.11E-5
Ggps1
Ggps1tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 1.11E-5
Dock10
Dock10tm1a(EUCOMM)Hmgu
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | EuroPhenome 1.12E-5
Map3k10
Map3k10tm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 1.27E-5
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.3E-5
Rars2
Rars2tm1a(EUCOMM)Wtsi
HET Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 1.34E-5
Dntt
Dntttm2b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 1.41E-5
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.54E-5
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.66E-5
Chrna7
Chrna7tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.69E-5
Cdca8
Cdca8tm1a(KOMP)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 1.72E-5
Usp11
Usp11tm1(KOMP)Wtsi
HEM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 1.83E-5
Slc22a8
Slc22a8tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.85E-5
BC055324
BC055324tm1a(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 1.85E-5
Taf2
Taf2tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.86E-5
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 1.93E-5
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.97E-5
Pbx3
Pbx3tm1a(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 2.03E-5
Usp12
Usp12tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 2.14E-5
Map3k1
Map3k1Gt(YTC001)Byg
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 2.18E-5
Aqp3
Aqp3tm2b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.22E-5
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.29E-5
Otud6a
Otud6atm1(KOMP)Vlcg
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MARC | IMPC 2.47E-5
Smyd2
Smyd2tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 2.48E-5
Map3k1
Map3k1Gt(YTC001)Byg
HET Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 2.51E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol RBRC | IMPC 2.53E-5
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.64E-5
Arrb2
Arrb2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 3.21E-5
Dnmt3a
Dnmt3atm1b(KOMP)Wtsi
HET Female postnatal increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 3.22E-5
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Fasted Clinical Chemistry | LDL-cholesterol MRC Harwell | EuroPhenome 3.57E-5
Pld5
Pld5tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.64E-5
Tusc5
Tusc5em2Tcp
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 3.84E-5
P2rx6
P2rx6tm2b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 4.01E-5
Akt2
Akt2tm1Wcs
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 4.08E-5
Ifi44
Ifi44tm1b(KOMP)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol TCP | IMPC 4.24E-5
Lrrc3
Lrrc3tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 4.29E-5
Cul7
Cul7tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 4.45E-5
Hspa5
Hspa5tm1.1(KOMP)Vlcg
HET Female postnatal increased circulating cholesterol level Plasma Chemistry | Total cholesterol JAX | IMPC 4.75E-5
Mtor
Mtortm1a(EUCOMM)Wtsi
HET Female postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 4.77E-5
Rnf10
Rnf10tm1a(KOMP)Wtsi
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 4.86E-5
Rars2
Rars2tm1a(EUCOMM)Wtsi
HET Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 4.94E-5
Aqp1
Aqp1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 4.95E-5
Rfc1
Rfc1tm1b(KOMP)Mbp
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 4.96E-5
Bmp10
Bmp10tm3b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 4.99E-5
Aco2
Aco2Gt(EUC0050e03)Hmgu
HET Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol HMGU | EuroPhenome 5.03E-5
Zfp715
Zfp715tm1a(EUCOMM)Hmgu
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | MGP 5.17E-5
Ska2
Ska2tm1b(KOMP)Wtsi
HET Female postnatal increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 5.2E-5
Fgf22
Fgf22tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 5.22E-5
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 5.31E-5
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 5.51E-5
Eps15
Eps15tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 5.58E-5
Entpd1
Entpd1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 5.97E-5
Eps15
Eps15tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 5.99E-5
Pttg1
Pttg1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 6.12E-5
Map3k10
Map3k10tm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 6.32E-5
Ccl9
Ccl9tm1(KOMP)Vlcg
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 6.49E-5
Prrt2
Prrt2tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 6.75E-5
Hsf2bp
Hsf2bptm1a(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol HMGU | EuroPhenome 6.96E-5
Skida1
Skida1tm1.1(KOMP)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 7.05E-5
Usp12
Usp12tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 7.09E-5
Rhpn1
Rhpn1tm1b(KOMP)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 7.2E-5
Tgfb1i1
Tgfb1i1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 7.2E-5
Tcaim
Tcaimtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 7.34E-5
Fndc7
Fndc7tm1.1(KOMP)Vlcg
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol UC Davis | IMPC 8.13E-5
Fgf10
Fgf10tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 8.26E-5
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 8.34E-5
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 8.67E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 9.23E-5
Yae1d1
Yae1d1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 9.34E-5
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HEM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 9.63E-5
Grm3
Grm3tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 9.71E-5
Cxcl9
Cxcl9tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 9.79E-5
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 9.97E-5

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