Phenotype: increased circulating cholesterol level

Definition greater than the normal amount in the blood of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues

Synonyms
  • high serum cholesterol level
  • high serum cholesterol level
  • increased total serum cholesterol level
  • increased total serum cholesterol level
  • increased total circulating cholesterol level
  • increased total plasma cholesterol level
  • elevated total circulating cholesterol level
  • elevated total plasma cholesterol level
  • elevated total serum cholesterol level
  • hypercholesterolaemia
  • hypercholesterolemia
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Related
Synonyms
  • Increased HDL cholesterol concentration
  • Increased HDL cholesterol concentration
  • Increased LDL cholesterol concentration
  • Increased LDL cholesterol concentration
  • Increased VLDL cholesterol concentration
  • increased circulating HDL cholesterol level
  • increased circulating LDL cholesterol level
  • increased circulating VLDL cholesterol level
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MP browserMP:0005178

Phenotype associations stats

2.90% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased circulating cholesterol level (123/4241)

2.05% females (86/4202) 2.65% males (112/4223)

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Gene variants with increased circulating cholesterol level

Total number of significant genotype-phenotype associations: 316

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Ldlr
Ldlrtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 3.64E-24
Apoe
Apoetm1Unc
HOM Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 4.03E-21
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol BCM | IMPC 6.03E-21
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 1.62E-20
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 1.92E-19
Apoe
Apoetm1Unc
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 2.02E-19
Nr1h4
Nr1h4
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol ICS | EuroPhenome 2.57E-18
Tchp
Tchptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 4.25E-18
Rxrg
Rxrg
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol ICS | EuroPhenome 1.64E-16
Reg3g
Reg3gtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.97E-16
Rxrg
Rxrg
HOM Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol ICS | EuroPhenome 6.76E-16
Cyp7a1
Cyp7a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 1.17E-13
D6Wsu163e
D6Wsu163etm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 1.31E-12
Ptpn23
Ptpn23tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 1.58E-12
Nr1h4
Nr1h4
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | EuroPhenome 7.02E-12
Tchp
Tchptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.59E-11
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MARC | IMPC 2.87E-11
Usp47
Usp47tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MARC | IMPC 8.7E-11
Slc5a5
Slc5a5tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 9.07E-11
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 1.36E-10
Ldlr
Ldlrtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 1.73E-10
Ptpn23
Ptpn23tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 3.77E-10
Usp47
Usp47tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 4.04E-10
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.54E-10
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.61E-10
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 1.29E-9
Reg3g
Reg3gtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 1.78E-9
Kif13b
Kif13btm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.73E-9
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 3.24E-9
Fbxo9
Fbxo9tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol TCP | IMPC 3.67E-9
Dntt
Dntttm2b(KOMP)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.54E-9
Fgf10
Fgf10tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 6.29E-9
Arrb2
Arrb2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 7.04E-9
Reg3g
Reg3gtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 8.34E-9
C4bp
C4bptm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 1.06E-8
Ap2a2
Ap2a2em1(IMPC)Wtsi
HET Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 1.07E-8
Rexo2
Rexo2tm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.38E-8
Sirt6
Sirt6tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | MGP 2.12E-8
Cyp7a1
Cyp7a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 3.03E-8
Gm20646
Gm20646em1(IMPC)Wtsi
HOM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 3.07E-8
Cidec
Cidectm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | EuroPhenome 3.24E-8
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 4.56E-8
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 4.99E-8
Pdzk1
Pdzk1tm2b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 5.92E-8
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 6.65E-8
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 7.3E-8
Abcg2
Abcg2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 9.78E-8
Otud6a
Otud6atm1(KOMP)Vlcg
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 1.08E-7
Snx8
Snx8tm2a(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 1.18E-7
Aspm
Aspmtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 1.51E-7
Ppil3
Ppil3tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 1.53E-7
Celsr1
Celsr1Scy
HET Female postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 1.62E-7
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.87E-7
Ntf5
Ntf5tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 2.04E-7
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.18E-7
Rfc1
Rfc1tm1b(KOMP)Mbp
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 2.58E-7
Pdzk1
Pdzk1tm2b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.85E-7
C4bp
C4bptm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 2.95E-7
Gm648
Gm648tm1e(KOMP)Wtsi
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 3.87E-7
Nodal
Nodaltm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.53E-7
Rnf10
Rnf10tm1a(KOMP)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 6.36E-7
Smyd2
Smyd2tm1a(KOMP)Wtsi
HOM Male postnatal increased circulating LDL cholesterol level Fasted Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 6.76E-7
Mbd1
Mbd1em1(IMPC)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 7.58E-7
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 7.71E-7
D6Wsu163e
D6Wsu163etm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 8.97E-7
Rexo2
Rexo2tm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 9.23E-7
H3f3b
H3f3btm1.1(KOMP)Mbp
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 1.01E-6
Dntt
Dntttm2b(KOMP)Wtsi
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 1.06E-6
Kansl1
Kansl1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.12E-6
Hspa5
Hspa5tm1.1(KOMP)Vlcg
HET Female postnatal increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 1.16E-6
Fam207a
Fam207atm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 1.26E-6
Slc5a5
Slc5a5tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.27E-6
Btbd9
Btbd9tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 1.28E-6
Ppil3
Ppil3tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.34E-6
Gm648
Gm648tm1e(KOMP)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.45E-6
Kansl1
Kansl1tm1b(EUCOMM)Hmgu
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 1.64E-6
Ntf5
Ntf5tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 1.79E-6
Akt2
Akt2tm1Wcs
HOM Female postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 1.79E-6
Nodal
Nodaltm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 2.03E-6
Fam207a
Fam207atm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 2.21E-6
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 2.63E-6
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.71E-6
Tm9sf4
Tm9sf4tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.72E-6
Rnf144b
Rnf144btm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 2.96E-6
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 3.33E-6
Slc24a4
Slc24a4tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 3.69E-6
Tm9sf4
Tm9sf4tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.7E-6
Lrba
Lrbaem1(IMPC)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.79E-6
Pdzk1
Pdzk1tm2b(EUCOMM)Wtsi
HET Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 4.3E-6
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 4.79E-6
Aspm
Aspmtm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 5.13E-6
BC055324
BC055324tm1a(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 5.44E-6
Btbd9
Btbd9tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 5.63E-6
Slc24a4
Slc24a4tm1b(KOMP)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 5.91E-6
Aqp1
Aqp1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 6.37E-6
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 6.75E-6
Irgm1
Irgm1em1(IMPC)Wtsi
HOM Female postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 6.75E-6
Yae1d1
Yae1d1tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 7.06E-6
Nat8f2
Nat8f2tm1.1(KOMP)Vlcg
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 7.22E-6
Il13
Il13tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 7.33E-6
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 7.41E-6
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 8.11E-6
Mbd1
Mbd1em1(IMPC)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 9.02E-6
Rasal3
Rasal3tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 9.1E-6
Dsg1c
Dsg1cem1(IMPC)Mbp
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol UC Davis | IMPC 9.29E-6
Celsr1
Celsr1Scy
HET Female postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 9.44E-6
Matn4
Matn4em1(IMPC)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.03E-5
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 1.1E-5
Fndc7
Fndc7tm1.1(KOMP)Vlcg
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 1.12E-5
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 1.22E-5
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.23E-5
Aqp3
Aqp3tm2b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.31E-5
Rars2
Rars2tm1a(EUCOMM)Wtsi
HET Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 1.34E-5
Chrna7
Chrna7tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.36E-5
Rnf144b
Rnf144btm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 1.42E-5
Kdm8
Kdm8tm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.44E-5
Klk14
Klk14tm1.1(KOMP)Vlcg
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 1.54E-5
Otud6a
Otud6atm1(KOMP)Vlcg
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MARC | IMPC 1.56E-5
Rasal3
Rasal3tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.63E-5
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Female postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.68E-5
H3f3b
H3f3btm1.1(KOMP)Mbp
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol UC Davis | IMPC 1.69E-5
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.8E-5
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.84E-5
BC055324
BC055324tm1a(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 1.85E-5
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 1.93E-5
Rnf10
Rnf10tm1a(KOMP)Wtsi
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 1.94E-5
Pbx3
Pbx3tm1a(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 2.03E-5
Map3k1
Map3k1Gt(YTC001)Byg
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | EuroPhenome 2.18E-5
Snx8
Snx8tm2a(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 2.41E-5
Smyd2
Smyd2tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 2.48E-5
Map3k1
Map3k1Gt(YTC001)Byg
HET Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 2.51E-5
Prl7b1
Prl7b1tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol UC Davis | IMPC 2.65E-5
Map3k10
Map3k10tm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 2.87E-5
P2rx6
P2rx6tm2b(EUCOMM)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 2.95E-5
Lrba
Lrbaem1(IMPC)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 3.06E-5
Stk32a
Stk32atm1a(EUCOMM)Wtsi
HOM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | MGP 3.1E-5
Arrb2
Arrb2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 3.11E-5
Dnmt3a
Dnmt3atm1b(KOMP)Wtsi
HET Female postnatal increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 3.22E-5
Tcaim
Tcaimtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 3.49E-5
Fgf22
Fgf22tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 3.49E-5
Ap2a2
Ap2a2em1(IMPC)Wtsi
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 3.5E-5
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Fasted Clinical Chemistry | LDL-cholesterol MRC Harwell | EuroPhenome 3.57E-5
D6Wsu163e
D6Wsu163etm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.6E-5
Abcg2
Abcg2tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 3.63E-5
Aqp1
Aqp1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 3.7E-5
Fbxo9
Fbxo9tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 3.71E-5
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.83E-5
Usp11
Usp11tm1(KOMP)Wtsi
HEM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 3.91E-5
Rfc1
Rfc1tm1b(KOMP)Mbp
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 3.99E-5
Aqp3
Aqp3tm2b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 4.07E-5
Akt2
Akt2tm1Wcs
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 4.08E-5
Grm3
Grm3tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 4.23E-5
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.25E-5
Cul7
Cul7tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 4.45E-5
Adar
Adartm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.49E-5
Hspa5
Hspa5tm1.1(KOMP)Vlcg
HET Female postnatal increased circulating cholesterol level Plasma Chemistry | Total cholesterol JAX | IMPC 4.63E-5
Lars
Larstm1b(KOMP)Wtsi
HET Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 4.68E-5
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.73E-5
Eps15
Eps15tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | EuroPhenome 4.84E-5
Syt7
Syt7em2(IMPC)H
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.91E-5
Rars2
Rars2tm1a(EUCOMM)Wtsi
HET Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol WTSI | EuroPhenome 4.94E-5
Ap2a2
Ap2a2em1(IMPC)Wtsi
HET Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 4.97E-5
Chrna7
Chrna7tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 4.98E-5
Prdm12
Prdm12tm2b(EUCOMM)Hmgu
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol TCP | IMPC 5.03E-5
Aco2
Aco2Gt(EUC0050e03)Hmgu
HET Male postnatal increased circulating cholesterol level Fasted Clinical Chemistry | Total cholesterol HMGU | EuroPhenome 5.03E-5
Ezh1
Ezh1tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 5.04E-5
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 5.08E-5
Mcu
Mcutm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 5.09E-5
Ska2
Ska2tm1b(KOMP)Wtsi
HET Female postnatal increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 5.1E-5
Zfp715
Zfp715tm1a(EUCOMM)Hmgu
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | MGP 5.17E-5
Eps15
Eps15tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | EuroPhenome 5.24E-5
Etv3
Etv3em1(IMPC)Wtsi
HOM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 5.44E-5
Glra4
Glra4tm1b(KOMP)Wtsi
HEM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 5.87E-5
Entpd1
Entpd1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 5.97E-5
Psg17
Psg17em1(IMPC)Wtsi
HOM Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 6.34E-5
Ccl9
Ccl9tm1(KOMP)Vlcg
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 6.56E-5
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 6.56E-5
Adal
Adaltm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 6.6E-5
Tgfb1i1
Tgfb1i1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 6.88E-5
Fgf10
Fgf10tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 6.93E-5
Hsf2bp
Hsf2bptm1a(EUCOMM)Hmgu
HOM Male postnatal increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol HMGU | EuroPhenome 6.96E-5
Snx8
Snx8tm2a(EUCOMM)Hmgu
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 7.17E-5
Cxcl9
Cxcl9tm1b(EUCOMM)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 7.56E-5
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol ICS | IMPC 7.6E-5
Pfkfb3
Pfkfb3tm1b(EUCOMM)Wtsi
HET Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 7.65E-5
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 7.87E-5
Acan
Acantm1b(EUCOMM)Hmgu
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 8.05E-5
Rhpn1
Rhpn1tm1b(KOMP)Wtsi
HOM Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 8.22E-5
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HET Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol JAX | IMPC 8.22E-5
Adal
Adaltm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 8.55E-5
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Female Male postnatal increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 8.59E-5
Tut4
Tut4tm1a(KOMP)Wtsi
HOM Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol WTSI | IMPC 8.6E-5
Kif18b
Kif18btm1a(EUCOMM)Wtsi
HET Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 8.84E-5
Usp46
Usp46em1(IMPC)Marc
HOM Female Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MARC | IMPC 9.34E-5
Rsbn1
Rsbn1tm1b(EUCOMM)Wtsi
HET Male postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol MRC Harwell | IMPC 9.57E-5
Usp12
Usp12tm1b(EUCOMM)Hmgu
HOM Female postnatal increased circulating cholesterol level Clinical Chemistry | Total cholesterol HMGU | IMPC 9.93E-5
Tmem189
Tmem189tm1a(KOMP)Wtsi
HOM Female Male postnatal increased circulating LDL cholesterol level Clinical Chemistry | LDL-cholesterol WTSI | IMPC 9.99E-5

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