Phenotype: decreased lymphocyte cell number
Definition fewer than normal number of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells
Synonyms
- reduced lymphocyte cell number
- reduced lymphocyte cell number
- decreased lymphocyte count
- decreased lymphocyte count
- decreased immune cell number
- reduced lymphocyte count
- lymphopenia
Related
Synonyms
Synonyms
- decreased Ly6C-positive immature NK cell number
- decreased Ly6C-positive immature NK cell number
- decreased pre-B cell number
- decreased pre-B cell number
- decreased large unstained cell number
- decreased NK cell number
- decreased Ly6C-positive mature NK cell number
- decreased memory T cell number
- decreased immature NK cell number
- Decreased proportion circulating T-helper cells
- absent gamma-delta T cells
- Lymphopenia
- decreased B cell number
- decreased uterine NK cell number
- decreased gamma-delta T cell number
- decreased Ly6C-positive immature NK cell number
- decreased T-helper cell number
- absent immature B cells
- Severe B lymphocytopenia
- absent T cells
- Severe B lymphocytopenia
- absent B cells
- absent T cells
- absent CD4-positive, alpha beta T cells
- decreased pre-B cell number
- decreased immature NK cell number
- absent B cells
- decreased activated T cell number
- absent lymphocyte
- decreased immature B cell number
- decreased mature B cell number
- absent immature B cells
- decreased memory T cell number
- decreased activated T cell number
- decreased KLRG1-positive NK cell number
- absent B cells
- Absence of CD8-positive T cells
- Decreased proportion circulating T-helper cells
- Absence of mature B cells
- Decrease in T cell count
- B lymphocytopenia
- decreased gamma-delta T cell number
- absent NK cells
- absent late pro-B cells
- decreased alpha-beta T cell number
- decreased mature NK cell number
- absent mature B cells
- absent uterine NK cells
- decreased T-helper cell number
- decreased alpha-beta T cell number
- absent regulatory T cells
- decreased T cell number
- absent NK cells
- decreased memory-marker NK cell number
- Absence of mature B cells
- absent double-negative T cells
- absent CD8-positive, alpha-beta T cells
- absent mature B cells
- absent T cells
- decreased regulatory T cell number
- Severe B lymphocytopenia
- decreased mature B cell number
- Decreased proportion of CD3-positive T cells
- absent uterine NK cells
- decreased regulatory T cell number
- decreased thymocyte number
- decreased Ly6C-positive mature NK cell number
- decreased thymocyte number
- decreased immature B cell number
- decreased single-positive T cell number
- decreased mature NK cell number
- Decreased proportion of CD3-positive T cells
- absent NK cells
- decreased KLRG1-positive NK cell number
- absent uterine NK cells
- absent NK T cells
- decreased single-positive T cell number
- decreased memory-marker NK cell number
- absent late pro-B cells
- decreased uterine NK cell number
- Reduced natural killer cell count
Procedure
- Hematology (IMPC, v2)
- Immunophenotyping (IMPC, v1)
- Bone marrow immunophenotyping (MGP, v1)
- Buffy coat peripheral blood leukocyte immunophenotyping (MGP, v1)
- Ear epidermis immunophenotyping (MGP, v1)
- FACS (ICS, v1)
- FACS (HRWL, v1)
- FACs Analysis (M-G-P, v1)
- FACs Analysis (ESLIM, v1)
- Haematology (GMC) (GMC, v1)
- Immunophenotyping (RBRCLA, v1)
- Immunophenotyping (ICS, v2)
- Immunophenotyping (HMGULA, v1)
- Immunophenotyping (TCPLA, v1)
- Immunophenotyping (UCDLA, v1)
- Mesenteric Lymph Node Immunophenotyping (MGP, v1)
- Spleen Immunophenotyping (MGP, v1)
- Whole blood peripheral blood leukocyte immunophenotyping (SLM, v1)
- Whole blood peripheral blood leukocyte immunophenotyping (MGP, v1)
MP browserMP:0005016
Phenotype associations stats
5.53% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased lymphocyte cell number (169/3055)
4.60% females (135/2932) 4.78% males (142/2972)
Select a parameter
Gene variants with decreased lymphocyte cell number
Total number of significant genotype-phenotype associations: 592
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Procedure | Parameter | Phenotyping Center | Source | P Value | Data |
---|---|---|---|---|---|---|---|---|
Adap1 Adap1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker NK cell number | Spleen Immunophenotyping | Resting NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Aicda Aicda^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased follicular B cell number | Mesenteric Lymph Node Immunophenotyping | Follicular B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Aicda Aicda^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased late germinal center B cell number | Mesenteric Lymph Node Immunophenotyping | Late germinal centre B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Arhgap17 Arhgap17^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased B-1a cell number | Spleen Immunophenotyping | B1a cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Arhgap17 Arhgap17^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased follicular B cell number | Spleen Immunophenotyping | Follicular B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Arhgap17 Arhgap17^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased mature B cell number | Whole blood peripheral blood leukocyte immunophenotyping | IgD+ mature B cell percentage | WTSI | 3i | 0.0 | ||
Arhgef1 Arhgef1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker gamma-delta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting gd T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Arhgef1 Arhgef1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased immature NK cell number | Spleen Immunophenotyping | Immature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Arhgef1 Arhgef1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased Ly6C-positive immature NK cell number | Spleen Immunophenotyping | Ly6C+ immature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Arhgef1 Arhgef1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased marginal zone B cell number | Spleen Immunophenotyping | Marginal zone B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Arhgef1 Arhgef1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-positive NK T cell number | Spleen Immunophenotyping | Resting CD4+ NKT cells - % of CD4+ NKT cells | WTSI | 3i | 0.0 | ||
Arhgef1 Arhgef1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased mature B cell number | Bone marrow immunophenotyping | Mature B cells (Hardy fraction F) - % of CD45+ | WTSI | 3i | 0.0 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased follicular B cell number | Spleen Immunophenotyping | Follicular B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker NK cell number | Spleen Immunophenotyping | Resting NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased B cell number | Whole blood peripheral blood leukocyte immunophenotyping | B cell percentage | WTSI | 3i | 0.0 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD25+ alpha beta regulatory T cell percentage | WTSI | 3i | 0.0 | ||
Brd2 Brd2^{em1(IMPC)Wtsi} |
HET | postnatal | decreased CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Brd2 Brd2^{em1(IMPC)Wtsi} |
HET | postnatal | decreased mature B cell number | Whole blood peripheral blood leukocyte immunophenotyping | IgD+ mature B cell percentage | WTSI | 3i | 0.0 | ||
Clpp Clpp^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-positive NK T cell number | Spleen Immunophenotyping | Effector CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Clpp Clpp^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-negative NK T cell number | Spleen Immunophenotyping | Effector CD4- NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Clpp Clpp^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Effector CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Clpp Clpp^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive NK T cell number | Spleen Immunophenotyping | Total CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Clpp Clpp^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK T cell number | Spleen Immunophenotyping | Total NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-positive NK T cell number | Mesenteric Lymph Node Immunophenotyping | Effector CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-negative NK T cell number | Mesenteric Lymph Node Immunophenotyping | Effector CD4- NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker NK cell number | Mesenteric Lymph Node Immunophenotyping | Effector NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker gamma-delta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting gd T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK T cell number | Mesenteric Lymph Node Immunophenotyping | Total NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total ab T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T-helper cell number | Spleen Immunophenotyping | CD4+ T helper cells - % of CD4+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased Ly6C-positive immature NK cell number | Spleen Immunophenotyping | Ly6C+ immature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased Ly6C-positive mature NK cell number | Spleen Immunophenotyping | Ly6C+ mature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased marginal zone B cell number | Spleen Immunophenotyping | Marginal zone B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive NK T cell number | Spleen Immunophenotyping | Total CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK cell number | Spleen Immunophenotyping | Total NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Spleen Immunophenotyping | Total T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cog6 Cog6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased transitional stage T2 B cell number | Spleen Immunophenotyping | Transitional 2 B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Cttnbp2 Cttnbp2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased transitional stage T1 B cell number | Spleen Immunophenotyping | Transitional 1 B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Cxcr2 Cxcr2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased immature B cell number | Bone marrow immunophenotyping | Immature B cells (Hardy fraction E) - % of CD45+ | WTSI | 3i | 0.0 | ||
Cxcr2 Cxcr2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased mature B cell number | Bone marrow immunophenotyping | Mature B cells (Hardy fraction F) - % of CD45+ | WTSI | 3i | 0.0 | ||
Cxcr2 Cxcr2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased pre-B cell number | Bone marrow immunophenotyping | Pre-B cells (Hardy fraction D) - % of CD45+ | WTSI | 3i | 0.0 | ||
Cxcr2 Cxcr2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Bone marrow immunophenotyping | T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cxcr2 Cxcr2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased B cell number | Bone marrow immunophenotyping | Total B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Cxcr2 Cxcr2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
D6Wsu163e D6Wsu163e^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased memory-marker NK cell number | Mesenteric Lymph Node Immunophenotyping | Effector NK cells - % of NK cells | WTSI | 3i | 0.0 | ||
D6Wsu163e D6Wsu163e^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total CD4+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Dph6 Dph6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Dph6 Dph6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Dph6 Dph6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased NK T cell number | Mesenteric Lymph Node Immunophenotyping | Total NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Dph6 Dph6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T-helper cell number | Spleen Immunophenotyping | CD4+ T helper cells - % of CD4+ | WTSI | 3i | 0.0 | ||
Dph6 Dph6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased Ly6C-positive mature NK cell number | Spleen Immunophenotyping | Ly6C+ mature NK cells - % of mature NK cells | WTSI | 3i | 0.0 | ||
Dph6 Dph6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased mature B cell number | Whole blood peripheral blood leukocyte immunophenotyping | IgD+ mature B cell percentage | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased immature B cell number | Bone marrow immunophenotyping | Immature B cells (Hardy fraction E) - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased memory-marker gamma-delta T cell number | Spleen Immunophenotyping | Effector gd T cells - % of gd T cells | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased follicular B cell number | Spleen Immunophenotyping | Follicular B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased KLRG1-positive NK cell number | Spleen Immunophenotyping | KLRG1+ NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Spleen Immunophenotyping | Resting Treg cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | Spleen Immunophenotyping | Total B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased B-2 B cell number | Spleen Immunophenotyping | Total B2 cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased transitional stage T1 B cell number | Spleen Immunophenotyping | Transitional 1 B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased mature B cell number | Whole blood peripheral blood leukocyte immunophenotyping | IgD+ mature B cell number | WTSI | 3i | 0.0 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased NK cell number | Whole blood peripheral blood leukocyte immunophenotyping | NK cell number | WTSI | 3i | 0.0 | ||
Fbxw26 Fbxw26^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased memory-marker NK cell number | Spleen Immunophenotyping | Resting NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gda Gda^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T-helper cell number | Mesenteric Lymph Node Immunophenotyping | CD4+ T helper cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gimap6 Gimap6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-negative NK T cell number | Spleen Immunophenotyping | Effector CD4- NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gimap6 Gimap6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-negative NK T cell number | Spleen Immunophenotyping | Total CD4- NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gm5544 Gm5544^{tm1a(KOMP)Wtsi} |
HET | postnatal | decreased marginal zone B cell number | Spleen Immunophenotyping | Marginal zone B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased KLRG1+ CD8 alpha beta T cell number | Mesenteric Lymph Node Immunophenotyping | KLRG1+ CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased KLRG1-positive NK cell number | Mesenteric Lymph Node Immunophenotyping | KLRG1+ NK cells - % of NK cells | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total ab T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T-helper cell number | Spleen Immunophenotyping | CD4+ T helper cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-positive NK T cell number | Spleen Immunophenotyping | Effector CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Spleen Immunophenotyping | Effector Treg cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased Ly6C-positive mature NK cell number | Spleen Immunophenotyping | Ly6C+ mature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased mature NK cell number | Spleen Immunophenotyping | Mature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-negative NK T cell number | Spleen Immunophenotyping | Resting CD4- NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive NK T cell number | Spleen Immunophenotyping | Total CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Spleen Immunophenotyping | Total CD4+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased NK cell number | Spleen Immunophenotyping | Total NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Spleen Immunophenotyping | Total Treg cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased transitional stage T2 B cell number | Spleen Immunophenotyping | Transitional 2 B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Hbs1l Hbs1l^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased mature B cell number | Bone marrow immunophenotyping | Mature B cells (Hardy fraction F) - % of B220+ | WTSI | 3i | 0.0 | ||
Hbs1l Hbs1l^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased memory-marker CD4-negative NK T cell number | Mesenteric Lymph Node Immunophenotyping | Effector CD4- NKT cells - % of CD4- NKT cells | WTSI | 3i | 0.0 | ||
Hbs1l Hbs1l^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Hbs1l Hbs1l^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T-helper cell number | Spleen Immunophenotyping | CD4+ T helper cells - % of CD4+ | WTSI | 3i | 0.0 | ||
Ifnar1 Ifnar1^{tm2a(EUCOMM)Wtsi} |
HOM | postnatal | decreased KLRG1-positive NK cell number | Whole blood peripheral blood leukocyte immunophenotyping | KLRG1+ mature NK cell percentage | WTSI | 3i | 0.0 | ||
Irf5 Irf5^{tm1e(EUCOMM)Wtsi} |
HOM | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number | WTSI | 3i | 0.0 | ||
Mkrn2 Mkrn2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased dendritic epidermal T cell number | Ear epidermis immunophenotyping | DETC coverage | WTSI | 3i | 0.0 | ||
Nrbp1 Nrbp1^{tm3b(EUCOMM)Wtsi} |
HET | postnatal | decreased CD4-positive, alpha beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total CD4+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Pclaf Pclaf^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Bone marrow immunophenotyping | T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Pclaf Pclaf^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased immature NK cell number | Spleen Immunophenotyping | Immature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Pclaf Pclaf^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD25+ alpha beta regulatory T cell percentage | WTSI | 3i | 0.0 | ||
Pepd Pepd^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased immature B cell number | Bone marrow immunophenotyping | Immature B cells (Hardy fraction E) - % of B220+ | WTSI | 3i | 0.0 | ||
Pepd Pepd^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased Ly6C-positive NK T cell number | Spleen Immunophenotyping | Ly6C+ NKT cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Pepd Pepd^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased transitional stage T1 B cell number | Spleen Immunophenotyping | Transitional 1 B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Rwdd1 Rwdd1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased Ly6C-positive mature NK cell number | Spleen Immunophenotyping | Ly6C+ mature NK cells - % of mature NK cells | WTSI | 3i | 0.0 | ||
Rwdd1 Rwdd1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Total CD8+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Rwdd1 Rwdd1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD25+ alpha beta regulatory T cell percentage | WTSI | 3i | 0.0 | ||
Sgsm1 Sgsm1^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Spleen Immunophenotyping | Total CD4+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased T-helper cell number | Mesenteric Lymph Node Immunophenotyping | CD4+ T helper cells - % of CD4+ | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased early germinal center B cell number | Mesenteric Lymph Node Immunophenotyping | Early germinal centre B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased germinal center B cell number | Mesenteric Lymph Node Immunophenotyping | Germinal centre B cells - % of B2 cells | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased KLRG1-positive NK cell number | Mesenteric Lymph Node Immunophenotyping | KLRG1+ NK cells - % of NK cells | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total CD4+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased gamma-delta T cell number | Mesenteric Lymph Node Immunophenotyping | Total gd T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased CD5-positive gamma-delta T cell number | Spleen Immunophenotyping | CD5+ gd T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased memory-marker CD4-positive NK T cell number | Spleen Immunophenotyping | Effector CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased memory-marker CD4-negative NK T cell number | Spleen Immunophenotyping | Effector CD4- NKT cells - % of CD4- NKT cells | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased Ly6C-positive mature NK cell number | Spleen Immunophenotyping | Ly6C+ mature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased CD4-positive NK T cell number | Spleen Immunophenotyping | Total CD4+ NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased NK T cell number | Spleen Immunophenotyping | Total NKT cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Sik3 Sik3^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased alpha-beta T cell number | Spleen Immunophenotyping | Total ab T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Spink14 Spink14^{tm1e(KOMP)Wtsi} |
HOM | postnatal | decreased immature NK cell number | Spleen Immunophenotyping | Immature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Spink14 Spink14^{tm1e(KOMP)Wtsi} |
HOM | postnatal | decreased mature NK cell number | Spleen Immunophenotyping | Mature NK cells - % of lymphocytes | WTSI | 3i | 0.0 | ||
Spink14 Spink14^{tm1e(KOMP)Wtsi} |
HOM | postnatal | decreased NK cell number | Spleen Immunophenotyping | Total NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem126a Tmem126a^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T-helper cell number | Spleen Immunophenotyping | CD4+ T helper cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem126a Tmem126a^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Spleen Immunophenotyping | Total CD4+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem126a Tmem126a^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased alpha-beta T cell number | Spleen Immunophenotyping | Total ab T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem127 Tmem127^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Mesenteric Lymph Node Immunophenotyping | Resting CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem127 Tmem127^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | Mesenteric Lymph Node Immunophenotyping | Total B cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem127 Tmem127^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased B-2 B cell number | Mesenteric Lymph Node Immunophenotyping | Total B2 cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem127 Tmem127^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Mesenteric Lymph Node Immunophenotyping | Total CD4+ T cells - % of ab T cells | WTSI | 3i | 0.0 | ||
Tmem127 Tmem127^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased NK cell number | Mesenteric Lymph Node Immunophenotyping | Total NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem127 Tmem127^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased memory-marker NK cell number | Spleen Immunophenotyping | Effector NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Tmem127 Tmem127^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased KLRG1-positive NK cell number | Spleen Immunophenotyping | KLRG1+ NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Traf2 Traf2^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased CD8-positive, alpha-beta T cell number | Spleen Immunophenotyping | Total CD8+ T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Traf2 Traf2^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased alpha-beta T cell number | Spleen Immunophenotyping | Total ab T cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Trappc9 Trappc9^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased KLRG1-positive NK cell number | Spleen Immunophenotyping | KLRG1+ NK cells - % of CD45+ | WTSI | 3i | 0.0 | ||
Vps13a Vps13a^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased T-helper cell number | Mesenteric Lymph Node Immunophenotyping | CD4+ T helper cells - % of CD4+ | WTSI | 3i | 0.0 | ||
Cd28 Cd28^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased T cell number | FACs Analysis | CD25+ percentage of CD4+ T cells | MRC Harwell | EuroPhenome | 3.99E-28 | ||
Spns2 Spns2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 1.64E-25 | ||
Elk4 Elk4^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | FACs Analysis | T cell CD4+ percentage | HMGU | EuroPhenome | 2.12E-21 | ||
Elk4 Elk4^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | HMGU | EuroPhenome | 8.19E-19 | ||
BC017643 BC017643^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 4.41E-17 | ||
Lrrk1 Lrrk1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 5.52E-16 | ||
Pou2af1 Pou2af1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 8.7E-16 | ||
Spns2 Spns2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 3.73E-15 | ||
Tmem189 Tmem189^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 7.42E-15 | ||
Ikzf3 Ikzf3^{tm1(KOMP)Vlcg} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | RBRC | IMPC | 1.22E-14 | ||
Trex1 Trex1^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 2.52E-14 | ||
Erf Erf^{tm1.1(KOMP)Mbp} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 5.19E-14 | ||
Spns2 Spns2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 8.34E-14 | ||
Tcf7 Tcf7^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | FACs Analysis | T cell CD4+ percentage | ICS | EuroPhenome | 1.27E-13 | ||
Fbxo15 Fbxo15^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MARC | IMPC | 1.47E-13 | ||
Elk4 Elk4^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | HMGU | EuroPhenome | 6.01E-13 | ||
Dlgap2 Dlgap2^{em1(IMPC)Mhzh} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MARC | IMPC | 7.66E-13 | ||
Tmem189 Tmem189^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 8.36E-13 | ||
Trim37 Trim37^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MARC | IMPC | 1.96E-12 | ||
Spns2 Spns2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased mature B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Mature B cell IgD+ percentage | WTSI | 3i | 3.78E-12 | ||
Lyn Lyn^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 9.41E-12 | ||
Lepr Lepr^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 1.25E-11 | ||
Rhbdd1 Rhbdd1^{tm1.1Mfm} |
HOM | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | MRC Harwell | EuroPhenome | 2.46E-11 | ||
Sgms1 Sgms1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NKT cell percentage | WTSI | 3i | 3.16E-11 | ||
Tcf7 Tcf7^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | ICS | EuroPhenome | 3.21E-11 | ||
Rab19 Rab19^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) differential count | ICS | IMPC | 5.94E-11 | ||
Pkn1 Pkn1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 8.13E-11 | ||
Tmem189 Tmem189^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 9.01E-11 | ||
Sgms1 Sgms1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 2.32E-10 | ||
Nrxn1 Nrxn1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 2.68E-10 | ||
Spns2 Spns2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | B cell CD19+ percentage | WTSI | 3i | 3.11E-10 | ||
Dnm2 Dnm2^{tm1.1(KOMP)Vlcg} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 5.21E-10 | ||
Pkn1 Pkn1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) count | MRC Harwell | IMPC | 7.71E-10 | ||
Fbxo7 Fbxo7^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 1.06E-9 | ||
Parvb Parvb^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased mature B cell number | FACs Analysis | Mature B cells IgD+ percentage | MRC Harwell | EuroPhenome | 1.62E-9 | ||
Acp2 Acp2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | MRC Harwell | EuroPhenome | 2.48E-9 | ||
Ric1 Ric1^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased mature B cell number | FACs Analysis | Mature B cells IgD+ percentage | MRC Harwell | EuroPhenome | 4.05E-9 | ||
Acp2 Acp2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | MRC Harwell | EuroPhenome | 4.26E-9 | ||
Parvb Parvb^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | CD25+ percentage of CD4+ T cells | MRC Harwell | EuroPhenome | 6.21E-9 | ||
Rtbdn Rtbdn^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Treg cell CD25+ percentage | WTSI | 3i | 8.37E-9 | ||
Ccdc83 Ccdc83^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MARC | IMPC | 1.2E-8 | ||
Fbxo7 Fbxo7^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 1.87E-8 | ||
Usp12 Usp12^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | HMGU | EuroPhenome | 2.3E-8 | ||
Arhgef4 Arhgef4^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | CD25+ percentage of CD4+ T cells | HMGU | EuroPhenome | 3.38E-8 | ||
Smc3 Smc3^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 3.91E-8 | ||
C3ar1 C3ar1^{tm1.1(KOMP)Vlcg} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 4.32E-8 | ||
Def6 Def6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 5.16E-8 | ||
Ppp2r2a Ppp2r2a^{tm1b(KOMP)Wtsi} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MARC | IMPC | 6.26E-8 | ||
Clpp Clpp^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased gamma-delta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | Gamma delta T cell percentage | WTSI | 3i | 1.0E-7 | ||
Kdm7a Kdm7a^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 1.5E-7 | ||
Elmod1 Elmod1^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 1.58E-7 | ||
Cyba Cyba^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NK cell percentage | WTSI | 3i | 1.95E-7 | ||
Plcg2 Plcg2^{Ali14} |
HET | postnatal | decreased mature B cell number | FACs Analysis | Mature B cells IgD+ percentage | HMGU | EuroPhenome | 2.09E-7 | ||
Ezr Ezr^{tm2a(EUCOMM)Wtsi} |
HET | postnatal | decreased NK T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NKT cell percentage | WTSI | 3i | 2.1E-7 | ||
Cnot4 Cnot4^{tm1b(EUCOMM)Wtsi} |
HET | postnatal | decreased KLRG1-positive NK cell number | Whole blood peripheral blood leukocyte immunophenotyping | KLRG1+ mature NK cell number | WTSI | 3i | 3.0E-7 | ||
Ric1 Ric1^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | MRC Harwell | EuroPhenome | 3.49E-7 | ||
Sgms1 Sgms1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NK cell percentage | WTSI | 3i | 4.22E-7 | ||
Ninj2 Ninj2^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased NK T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NKT cell percentage | WTSI | 3i | 5.24E-7 | ||
Parvb Parvb^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK cell number | FACs Analysis | NK cell percentage | MRC Harwell | EuroPhenome | 5.55E-7 | ||
Ccdc129 Ccdc129^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MARC | IMPC | 6.03E-7 | ||
Abcc5 Abcc5^{em1(IMPC)H} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 6.36E-7 | ||
Plcg2 Plcg2^{Ali14} |
HET | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | HMGU | EuroPhenome | 6.48E-7 | ||
Uevld Uevld^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased B cell number | Whole blood peripheral blood leukocyte immunophenotyping | B cell number | WTSI | 3i | 7.0E-7 | ||
Uevld Uevld^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased mature B cell number | Whole blood peripheral blood leukocyte immunophenotyping | IgD+ mature B cell number | WTSI | 3i | 7.0E-7 | ||
Mcf2l Mcf2l^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 7.89E-7 | ||
Calhm2 Calhm2^{tm1b(KOMP)Mbp} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 8.84E-7 | ||
Gimap6 Gimap6^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased NK T cell number | Whole blood peripheral blood leukocyte immunophenotyping | NKT cell number | WTSI | 3i | 1.1E-6 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | Whole blood peripheral blood leukocyte immunophenotyping | B cell percentage | WTSI | 3i | 1.1E-6 | ||
Sept10 Sept10^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell percentage | WTSI | 3i | 1.1E-6 | ||
Tmod1 Tmod1^{tm1a(KOMP)Wtsi} |
HET | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 1.58E-6 | ||
Acsl4 Acsl4^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased NK cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NK cell percentage | WTSI | 3i | 1.6E-6 | ||
Arhgap22 Arhgap22^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 1.7E-6 | ||
Brpf1 Brpf1^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | MRC Harwell | EuroPhenome | 1.89E-6 | ||
Arpc1b Arpc1b^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NK cell percentage | WTSI | 3i | 1.91E-6 | ||
Isg20 Isg20^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased NK T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NKT cell percentage | WTSI | 3i | 1.96E-6 | ||
Sgms1 Sgms1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 2.08E-6 | ||
Fbxo7 Fbxo7^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 2.09E-6 | ||
Il10ra Il10ra^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | ICS | IMPC | 2.16E-6 | ||
Nfkbid Nfkbid^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | HMGU | EuroPhenome | 2.29E-6 | ||
Atn1 Atn1^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 2.33E-6 | ||
Eftud2 Eftud2^{tm1b(KOMP)Wtsi} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | ICS | IMPC | 2.55E-6 | ||
Chst12 Chst12^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MARC | IMPC | 2.92E-6 | ||
Arsg Arsg^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | B cell CD19+ percentage | WTSI | 3i | 3.04E-6 | ||
Bud23 Bud23^{em2(IMPC)H} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 3.22E-6 | ||
Trex1 Trex1^{tm1(KOMP)Wtsi} |
HOM | postnatal | decreased NK cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NK cell percentage | WTSI | 3i | 3.3E-6 | ||
Mrap2 Mrap2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | B cell CD19+ percentage | WTSI | 3i | 3.32E-6 | ||
Sdc4 Sdc4^{tm2b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 3.33E-6 | ||
Smc3 Smc3^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 3.38E-6 | ||
Acp2 Acp2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | FACs Analysis | T cell CD4+ percentage | MRC Harwell | EuroPhenome | 3.53E-6 | ||
Emc10 Emc10^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 3.62E-6 | ||
Arhgap22 Arhgap22^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 3.75E-6 | ||
Ddhd1 Ddhd1^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | B cell CD19+ percentage | WTSI | 3i | 4.09E-6 | ||
Slc25a21 Slc25a21^{tm1d(KOMP)Wtsi} |
HOM | postnatal | decreased NK T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NKT cell percentage | WTSI | 3i | 4.22E-6 | ||
Ing4 Ing4^{em2(IMPC)Tcp} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | TCP | IMPC | 5.62E-6 | ||
Tram2 Tram2^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 5.85E-6 | ||
Col4a5 Col4a5^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 6.05E-6 | ||
Prss50 Prss50^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | MRC Harwell | EuroPhenome | 6.54E-6 | ||
Brd2 Brd2^{em1(IMPC)Wtsi} |
HET | postnatal | decreased KLRG1+ CD8 alpha beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ KLRG1+ alpha beta T cell number | WTSI | 3i | 8.3E-6 | ||
Mmp11 Mmp11^{tm1a(EUCOMM)Hmgu} |
HET | postnatal | decreased T cell number | FACs Analysis | CD25+ percentage of CD4+ T cells | HMGU | EuroPhenome | 8.8E-6 | ||
Lyn Lyn^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) count | MRC Harwell | IMPC | 9.45E-6 | ||
Def6 Def6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 1.05E-5 | ||
Tnik Tnik^{tm3a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Treg cell CD25+ percentage | WTSI | 3i | 1.05E-5 | ||
Mcf2l Mcf2l^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 1.09E-5 | ||
Mysm1 Mysm1^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | HMGU | EuroPhenome | 1.18E-5 | ||
Fndc9 Fndc9^{tm1.1(KOMP)Vlcg} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 1.48E-5 | ||
Dctn1 Dctn1^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 1.65E-5 | ||
Arhgap22 Arhgap22^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 1.65E-5 | ||
Usp3 Usp3^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Treg cell CD25+ percentage | WTSI | 3i | 1.65E-5 | ||
Trim56 Trim56^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD25+ alpha beta regulatory T cell percentage | WTSI | 3i | 1.74E-5 | ||
Mysm1 Mysm1^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased mature B cell number | FACs Analysis | Mature B cells IgD+ percentage | HMGU | EuroPhenome | 1.8E-5 | ||
Fam234b Fam234b^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | HMGU | EuroPhenome | 1.82E-5 | ||
Tram2 Tram2^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 1.86E-5 | ||
Elmo1 Elmo1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased mature B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Mature B cell IgD+ percentage | WTSI | 3i | 1.87E-5 | ||
Stambp Stambp^{tm1b(EUCOMM)Hmgu} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 1.87E-5 | ||
Cidec Cidec^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | FACs Analysis | T cell CD4+ percentage | HMGU | EuroPhenome | 1.88E-5 | ||
Pms1 Pms1^{tm1.1(KOMP)Vlcg} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 1.99E-5 | ||
Alox15 Alox15^{tm1b(KOMP)Mbp} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 2.15E-5 | ||
Abhd3 Abhd3^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MARC | IMPC | 2.33E-5 | ||
Irf5 Irf5^{tm1e(EUCOMM)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell number | WTSI | 3i | 2.39E-5 | ||
Rwdd1 Rwdd1^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ CD44+ CD62L- alpha beta effector T cell number | WTSI | 3i | 2.39E-5 | ||
Duoxa2 Duoxa2^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased NK T cell number | Whole blood peripheral blood leukocyte immunophenotyping | NKT cell number | WTSI | 3i | 2.54E-5 | ||
Arid1b Arid1b^{tm1b(EUCOMM)Hmgu} |
HET | postnatal | decreased mature B cell number | Whole blood peripheral blood leukocyte immunophenotyping | IgD+ mature B cell percentage | WTSI | 3i | 2.56E-5 | ||
Zfp84 Zfp84^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ alpha beta T cell percentage | WTSI | 3i | 2.57E-5 | ||
Plin2 Plin2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Treg cell CD25+ percentage | WTSI | 3i | 2.67E-5 | ||
Plin2 Plin2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 2.75E-5 | ||
1500015O10Rik 1500015O10Rik^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) count | ICS | IMPC | 2.78E-5 | ||
Lix1l Lix1l^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 2.78E-5 | ||
Prss50 Prss50^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | MRC Harwell | EuroPhenome | 2.83E-5 | ||
Zfp84 Zfp84^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased alpha-beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | Alpha beta T cell percentage | WTSI | 3i | 2.85E-5 | ||
Aldh2 Aldh2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | MRC Harwell | EuroPhenome | 2.85E-5 | ||
Fbxo7 Fbxo7^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NKT cell percentage | WTSI | 3i | 2.88E-5 | ||
Slc38a10 Slc38a10^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NK cell percentage | WTSI | 3i | 2.99E-5 | ||
Cstb Cstb^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | ICS | IMPC | 3.03E-5 | ||
Asxl1 Asxl1^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | HMGU | EuroPhenome | 3.06E-5 | ||
Fam96a Fam96a^{tm2a(EUCOMM)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 3.1E-5 | ||
Uevld Uevld^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased gamma-delta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | Gamma delta T cell number | WTSI | 3i | 3.14E-5 | ||
Aspm Aspm^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 3.15E-5 | ||
Gmds Gmds^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | Whole blood peripheral blood leukocyte immunophenotyping | Total T cell percentage | WTSI | 3i | 3.16E-5 | ||
Zfp84 Zfp84^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased T cell number | Whole blood peripheral blood leukocyte immunophenotyping | Total T cell percentage | WTSI | 3i | 3.16E-5 | ||
Itch Itch^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | MRC Harwell | IMPC | 3.16E-5 | ||
Klhl21 Klhl21^{tm1a(KOMP)Wtsi} |
HET | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 3.22E-5 | ||
Coro1a Coro1a^{tm1.1(KOMP)Vlcg} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 3.25E-5 | ||
Ddx52 Ddx52^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased NK cell number | FACs Analysis | NK cell percentage | ICS | EuroPhenome | 3.26E-5 | ||
Aldh2 Aldh2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | FACs Analysis | T cell CD4+ percentage | MRC Harwell | EuroPhenome | 3.3E-5 | ||
Entpd1 Entpd1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased NK cell number | FACs Analysis | NK cell percentage | HMGU | EuroPhenome | 3.31E-5 | ||
Tmod1 Tmod1^{tm1a(KOMP)Wtsi} |
HET | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Treg cell CD25+ percentage | WTSI | 3i | 3.44E-5 | ||
Bach2 Bach2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased gamma-delta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | Gamma delta T cell percentage | WTSI | 3i | 3.51E-5 | ||
Trappc9 Trappc9^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased gamma-delta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | Gamma delta T cell percentage | WTSI | 3i | 3.51E-5 | ||
Mms22l Mms22l^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 3.61E-5 | ||
Wdr37 Wdr37^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | B cell CD19+ percentage | WTSI | 3i | 3.84E-5 | ||
Cbx6 Cbx6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 3.85E-5 | ||
Klhl21 Klhl21^{tm1a(KOMP)Wtsi} |
HET | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 3.93E-5 | ||
Rspo1 Rspo1^{tm2b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | ICS | IMPC | 3.94E-5 | ||
March9 March9^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | MRC Harwell | EuroPhenome | 3.97E-5 | ||
Elk4 Elk4^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased mature B cell number | FACs Analysis | Mature B cells IgD+ percentage | HMGU | EuroPhenome | 4.09E-5 | ||
Pknox1 Pknox1^{Gt(EUCJ0079d10)Hmgu} |
HET | postnatal | decreased mature B cell number | FACs Analysis | Mature B cells IgD+ percentage | HMGU | EuroPhenome | 4.45E-5 | ||
Smarcal1 Smarcal1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 4.7E-5 | ||
Slc5a7 Slc5a7^{tm1a(KOMP)Wtsi} |
HET | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 4.71E-5 | ||
Gba2 Gba2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Treg cell CD25+ percentage | WTSI | 3i | 4.76E-5 | ||
Fam110b Fam110b^{tm1e(EUCOMM)Wtsi} |
HET | postnatal | decreased mature B cell number | FACs Analysis | Mature B cells IgD+ percentage | HMGU | EuroPhenome | 4.84E-5 | ||
Serf1 Serf1^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | MRC Harwell | EuroPhenome | 4.87E-5 | ||
Lrrc3 Lrrc3^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | ICS | IMPC | 4.89E-5 | ||
Zfp595 Zfp595^{tm1b(KOMP)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 5.1E-5 | ||
Xbp1 Xbp1^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased T cell number | FACs Analysis | CD25+ percentage of CD4+ T cells | HMGU | EuroPhenome | 5.13E-5 | ||
Esr2 Esr2^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MARC | IMPC | 5.27E-5 | ||
Lyplal1 Lyplal1^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased NK T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | NKT cell percentage | WTSI | 3i | 5.28E-5 | ||
Eci3 Eci3^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 5.39E-5 | ||
Cnot4 Cnot4^{tm1b(EUCOMM)Wtsi} |
HET | postnatal | decreased KLRG1+ CD8 alpha beta T cell number | Whole blood peripheral blood leukocyte immunophenotyping | CD8+ KLRG1+ alpha beta T cell number | WTSI | 3i | 5.62E-5 | ||
Wrnip1 Wrnip1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | HMGU | EuroPhenome | 5.75E-5 | ||
Elmo1 Elmo1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | Treg cell CD25+ percentage | WTSI | 3i | 5.77E-5 | ||
Tnfrsf1b Tnfrsf1b^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | ICS | EuroPhenome | 5.91E-5 | ||
Pknox1 Pknox1^{Gt(EUCJ0079d10)Hmgu} |
HET | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | HMGU | EuroPhenome | 6.02E-5 | ||
Dtwd1 Dtwd1^{em1(IMPC)Marc} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MARC | IMPC | 6.29E-5 | ||
Nodal Nodal^{tm1Rob} |
HET | postnatal | decreased B cell number | FACs Analysis | B cell CD19+ percentage | MRC Harwell | EuroPhenome | 6.35E-5 | ||
Stx7 Stx7^{em1(IMPC)Rbrc} |
HOM | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) count | RBRC | IMPC | 6.65E-5 | ||
Gper1 Gper1^{tm1Dgen} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | HMGU | EuroPhenome | 6.86E-5 | ||
Abca4 Abca4^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 6.97E-5 | ||
5330417C22Rik 5330417C22Rik^{tm1b(EUCOMM)Hmgu} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | ICS | IMPC | 7.14E-5 | ||
Taf8 Taf8^{tm2b(EUCOMM)Wtsi} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 7.31E-5 | ||
Tiparp Tiparp^{tm1b(EUCOMM)Wtsi} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 7.35E-5 | ||
Aldh2 Aldh2^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | MRC Harwell | EuroPhenome | 7.44E-5 | ||
Gper1 Gper1^{tm1Dgen} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | FACs Analysis | T cell CD8+ percentage | HMGU | EuroPhenome | 7.78E-5 | ||
Avp Avp^{tm1b(EUCOMM)Wtsi} |
HET | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) count | MRC Harwell | IMPC | 7.88E-5 | ||
Scaper Scaper^{tm1b(EUCOMM)Hmgu} |
HOM | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) differential count | ICS | IMPC | 8.11E-5 | ||
Sec1 Sec1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD8+ percentage | WTSI | 3i | 8.21E-5 | ||
March5 March5^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 8.67E-5 | ||
Cidec Cidec^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | HMGU | EuroPhenome | 8.7E-5 | ||
Nsmf Nsmf^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD4-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage | WTSI | 3i | 8.84E-5 | ||
Ikzf3 Ikzf3^{tm1(KOMP)Vlcg} |
HOM | postnatal | decreased large unstained cell number | Hematology | Large Unstained Cell (LUC) count | RBRC | IMPC | 8.87E-5 | ||
Dnmt3a Dnmt3a^{tm1a(KOMP)Wtsi} |
HOM | postnatal | decreased effector memory CD8-positive, alpha-beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | CD8+CD44+CD62L- percentage | WTSI | 3i | 8.9E-5 | ||
Got1 Got1^{tm1b(EUCOMM)Hmgu} |
HET | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte cell count | MRC Harwell | IMPC | 9.31E-5 | ||
Polr3f Polr3f^{tm1a(EUCOMM)Wtsi} |
HET | postnatal | decreased B cell number | Buffy coat peripheral blood leukocyte immunophenotyping | B cell CD19+ percentage | WTSI | 3i | 9.33E-5 | ||
Cbx6 Cbx6^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 9.36E-5 | ||
Sec1 Sec1^{tm1a(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 9.72E-5 | ||
Slc5a7 Slc5a7^{tm1a(KOMP)Wtsi} |
HET | postnatal | decreased CD4-positive, alpha beta T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD4+ percentage | WTSI | 3i | 9.78E-5 | ||
Cd22 Cd22^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased lymphocyte cell number | Hematology | Lymphocyte differential count | UC Davis | IMPC | 9.8E-5 | ||
Eci3 Eci3^{tm1b(EUCOMM)Wtsi} |
HOM | postnatal | decreased T cell number | Buffy coat peripheral blood leukocyte immunophenotyping | T cell CD3+ percentage | WTSI | 3i | 9.83E-5 | ||
Serf1 Serf1^{tm1a(EUCOMM)Hmgu} |
HOM | postnatal | decreased T cell number | FACs Analysis | T cell CD3+ percentage | MRC Harwell | EuroPhenome | 9.87E-5 |