Phenotype: decreased lymphocyte cell number

Definition fewer than normal number of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells

Synonyms
  • reduced lymphocyte cell number
  • reduced lymphocyte cell number
  • decreased lymphocyte count
  • decreased lymphocyte count
  • decreased immune cell number
  • reduced lymphocyte count
  • lymphopenia
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Related
Synonyms
  • Absence of B cells
  • Absence of B cells
  • Absent B cells
  • Absent B cells
  • Absent natural killer cells
  • Severe B lymphocytopenia
  • absence of immune cell
  • absence of lymphocyte
  • absence of natural killer cells
  • absent B cells
  • absent GMG cells
  • absent NK cells
  • absent T cells
  • absent dNK cells
  • absent decidual NK cells
  • absent decidual natural killer cells
  • absent granulated metrial gland cells
  • absent lymphocyte
  • absent natural killer cells
  • absent uNK cells
  • absent uterine NK cells
  • absent uterine natural killer cells
  • loss of immune cell
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Phenotype associations stats

7.32% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased lymphocyte cell number (132/1803)

6.21% females (109/1756) 6.81% males (122/1792)

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Gene variants with decreased lymphocyte cell number

Total number of significant genotype-phenotype associations: 278

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Cd28
Cd28tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased T cell number FACs Analysis | CD25+ percentage of CD4+ T cells MRC Harwell | EuroPhenome 3.99E-28
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD4-positive, alpha beta T cell number FACs Analysis | T cell CD4+ percentage HMGU | EuroPhenome 3.66E-20
Tcf7
Tcf7tm1a(EUCOMM)Wtsi
HOM Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage ICS | EuroPhenome 4.63E-19
Pou2af1
Pou2af1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 4.79E-18
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage HMGU | EuroPhenome 6.97E-18
Dnase1l2
Dnase1l2em2Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 9.41E-18
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 5.52E-16
Hnrnpd
Hnrnpdtm1b(KOMP)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MARC | IMPC 1.07E-14
C3ar1
C3ar1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.46E-13
Fbxo15
Fbxo15em1Marc
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MARC | IMPC 3.07E-13
Tcf7
Tcf7tm1a(EUCOMM)Wtsi
HOM Male postnatal decreased CD4-positive, alpha beta T cell number FACs Analysis | T cell CD4+ percentage ICS | MGP 7.35E-13
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage HMGU | EuroPhenome 1.65E-12
Dlgap2
Dlgap2em1Mhzh
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MARC | IMPC 1.76E-12
Trim37
Trim37em1Marc
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MARC | IMPC 2.49E-12
Lyn
Lyntm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MRC Harwell | IMPC 9.38E-12
Calhm2
Calhm2tm1b(KOMP)Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.38E-11
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MRC Harwell | IMPC 1.56E-11
Rhbdd1
Rhbdd1tm1.1Mfm
HOM Female Male postnatal decreased B cell number FACs Analysis | B cell CD19+ percentage MRC Harwell | EuroPhenome 2.46E-11
2210408I21Rik
2210408I21Riktm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.62E-11
Ikzf3
Ikzf3tm1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count RBRC | IMPC 7.58E-11
Pde6a
Pde6aem1Mbp
HOM Female postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count UC Davis | IMPC 7.65E-11
Pkn1
Pkn1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MRC Harwell | IMPC 8.13E-11
Crabp1
Crabp1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.17E-10
Rab19
Rab19tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) differential count ICS | IMPC 2.83E-10
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 2.95E-10
Pkn1
Pkn1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) count MRC Harwell | IMPC 7.71E-10
Nr1d2
Nr1d2tm1Dgen
HOM Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage ICS | EuroPhenome 8.65E-10
Cwc22
Cwc22em1Mbp
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 8.91E-10
Olfr380
Olfr380em1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.0E-9
Parvb
Parvbtm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased mature B cell number FACs Analysis | Mature B cells IgD+ percentage MRC Harwell | EuroPhenome 1.62E-9
Acp2
Acp2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage MRC Harwell | EuroPhenome 2.48E-9
Fndc9
Fndc9tm1.1(KOMP)Vlcg
HOM Female postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.53E-9
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Male postnatal decreased mature B cell number FACs Analysis | Mature B cells IgD+ percentage MRC Harwell | EuroPhenome 4.05E-9
Acp2
Acp2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage MRC Harwell | EuroPhenome 4.26E-9
Parvb
Parvbtm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased T cell number FACs Analysis | CD25+ percentage of CD4+ T cells MRC Harwell | EuroPhenome 6.21E-9
Nr1d2
Nr1d2tm1Dgen
HOM Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage ICS | EuroPhenome 8.97E-9
Alox15
Alox15tm1b(KOMP)Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.14E-8
Taf8
Taf8tm2b(EUCOMM)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.46E-8
Sgtb
Sgtbem1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.21E-8
Ccdc83
Ccdc83em1Marc
HOM Female postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MARC | IMPC 2.3E-8
Pms1
Pms1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.33E-8
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased T cell number FACs Analysis | CD25+ percentage of CD4+ T cells HMGU | EuroPhenome 4.55E-8
Vwa2
Vwa2em1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count UC Davis | IMPC 6.86E-8
B3galt2
B3galt2tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 9.78E-8
Ppp2r2a
Ppp2r2atm1b(KOMP)Wtsi
HET Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MARC | IMPC 1.26E-7
Tiparp
Tiparptm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.31E-7
Fkbp10
Fkbp10tm2a(EUCOMM)Wtsi
HET Male postnatal decreased B cell number FACs Analysis | B cell CD19+ percentage ICS | EuroPhenome 1.33E-7
Gper1
Gper1tm1Dgen
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage HMGU | EuroPhenome 1.36E-7
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MRC Harwell | IMPC 1.58E-7
Ifng
Ifngtm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.59E-7
Parg
Pargtm2b(KOMP)Mbp
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.68E-7
Dyrk1b
Dyrk1btm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) differential count ICS | IMPC 1.86E-7
Mybl2
Mybl2tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 3.28E-7
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Male postnatal decreased B cell number FACs Analysis | B cell CD19+ percentage MRC Harwell | EuroPhenome 3.49E-7
Plcg2
Plcg2Ali14
HET Female Male postnatal decreased mature B cell number FACs Analysis | Mature B cells IgD+ percentage HMGU | EuroPhenome 3.86E-7
Tlr4
Tlr4tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 4.51E-7
Parvb
Parvbtm1a(EUCOMM)Wtsi
HOM Male postnatal decreased NK cell number FACs Analysis | NK cell percentage MRC Harwell | EuroPhenome 5.55E-7
Pygo2
Pygo2tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 5.61E-7
Fam234b
Fam234btm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage HMGU | EuroPhenome 5.95E-7
Abcc5
Abcc5em1H
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MRC Harwell | IMPC 7.3E-7
Stx7
Stx7em1Rbrc
HOM Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) differential count RBRC | IMPC 7.51E-7
Ccdc129
Ccdc129em1Marc
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MARC | IMPC 8.09E-7
Dnm2
Dnm2tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 8.71E-7
Gper1
Gper1tm1Dgen
HOM Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage HMGU | EuroPhenome 9.33E-7
Rft1
Rft1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 9.9E-7
Adipor2
Adipor2tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 1.57E-6
Brpf1
Brpf1tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage MRC Harwell | EuroPhenome 1.89E-6
Erf
Erftm1.1(KOMP)Mbp
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.13E-6
Atn1
Atn1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 2.33E-6
Slc25a14
Slc25a14em1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.36E-6
Ifitm1
Ifitm1not yet assigned
HOM Male postnatal decreased mature B cell number FACs Analysis | Mature B cells IgD+ percentage HMGU | EuroPhenome 2.9E-6
Synpo2
Synpo2tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count ICS | IMPC 3.25E-6
Setx
Setxtm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count ICS | IMPC 3.26E-6
Acp2
Acp2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD4-positive, alpha beta T cell number FACs Analysis | T cell CD4+ percentage MRC Harwell | EuroPhenome 3.53E-6
Fabp1
Fabp1tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) count MRC Harwell | IMPC 3.56E-6
Emc10
Emc10tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 3.62E-6
Prkab1
Prkab1em2Mbp
HOM Female postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count UC Davis | IMPC 3.67E-6
Atg4c
Atg4cem2Marc
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MARC | IMPC 3.76E-6
Sdc4
Sdc4tm2b(KOMP)Wtsi
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 4.05E-6
Bahd1
Bahd1tm2b(KOMP)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count ICS | IMPC 4.16E-6
Gper1
Gper1tm1Dgen
HOM Female Male postnatal decreased CD4-positive, alpha beta T cell number FACs Analysis | T cell CD4+ percentage HMGU | EuroPhenome 4.18E-6
Bfsp1
Bfsp1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 4.96E-6
Sec61b
Sec61bem1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count UC Davis | IMPC 5.49E-6
Nalcn
Nalcnem1Mbp
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 5.78E-6
Mctp1
Mctp1em1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 5.96E-6
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HOM Female postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 6.05E-6
Prss50
Prss50tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage MRC Harwell | EuroPhenome 6.54E-6
Pdik1l
Pdik1lem1Mbp
HOM Female postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count UC Davis | IMPC 6.81E-6
Tdo2
Tdo2tm1b(KOMP)Mbp
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 7.12E-6
Tdo2
Tdo2tm1b(KOMP)Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 7.12E-6
Mmp11
Mmp11tm1a(EUCOMM)Hmgu
HET Female postnatal decreased T cell number FACs Analysis | CD25+ percentage of CD4+ T cells HMGU | EuroPhenome 8.01E-6
Slc38a11
Slc38a11tm2b(KOMP)Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 9.03E-6
Lyn
Lyntm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) count MRC Harwell | IMPC 9.34E-6
Ikzf3
Ikzf3tm1(KOMP)Vlcg
HOM Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) count RBRC | IMPC 1.02E-5
Npr3
Npr3tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.14E-5
Npr3
Npr3tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.14E-5
Usp20
Usp20tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased KLRG1+ CD4 alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ KLRG1+ alpha beta T cell number WTSI | 3i 1.17E-5
Cd22
Cd22tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.3E-5
Arid1b
Arid1btm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased NK T cell number Whole blood peripheral blood leukocyte immunophenotyping | NKT cell number WTSI | 3i 1.31E-5
Enam
Enamem1Tcp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.32E-5
Prrc2b
Prrc2btm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased KLRG1+ CD4 alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ KLRG1+ alpha beta T cell percentage WTSI | 3i 1.61E-5
Txk
Txktm2b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.64E-5
Fndc3b
Fndc3btm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 1.67E-5
5430419D17Rik
5430419D17Rikem1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count UC Davis | IMPC 1.94E-5
Pbld2
Pbld2tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.25E-5
5330417C22Rik
5330417C22Riktm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count ICS | IMPC 2.28E-5
5330417C22Rik
5330417C22Riktm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count ICS | IMPC 2.28E-5
Ica1
Ica1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.38E-5
Foxn1
Foxn1tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.41E-5
Foxn1
Foxn1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.41E-5
Ankfy1
Ankfy1tm1b(KOMP)Mbp
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.49E-5
Il18rap
Il18raptm1b(KOMP)Wtsi
HOM Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) differential count ICS | IMPC 2.58E-5
Prss50
Prss50tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage MRC Harwell | EuroPhenome 2.83E-5
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage MRC Harwell | EuroPhenome 2.85E-5
Slc35g1
Slc35g1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 2.99E-5
Abhd3
Abhd3em1Marc
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MARC | IMPC 3.01E-5
Rspo1
Rspo1tm2b(KOMP)Wtsi
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count ICS | IMPC 3.11E-5
Fryl
Fryltm1b(KOMP)Wtsi
HET Female Male postnatal decreased KLRG1+ CD4 alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ KLRG1+ alpha beta T cell percentage WTSI | 3i 3.13E-5
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count MRC Harwell | IMPC 3.23E-5
Ddx52
Ddx52tm1a(EUCOMM)Wtsi
HET Male postnatal decreased NK cell number FACs Analysis | NK cell percentage ICS | MGP 3.26E-5
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD4-positive, alpha beta T cell number FACs Analysis | T cell CD4+ percentage MRC Harwell | EuroPhenome 3.3E-5
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count ICS | IMPC 3.31E-5
Mtpap
Mtpaptm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 3.4E-5
Il10ra
Il10ratm1b(KOMP)Wtsi
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count ICS | IMPC 3.46E-5
March9
March9tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased B cell number FACs Analysis | B cell CD19+ percentage MRC Harwell | EuroPhenome 3.97E-5
Cidec
Cidectm1a(EUCOMM)Wtsi
HOM Female postnatal decreased CD4-positive, alpha beta T cell number FACs Analysis | T cell CD4+ percentage HMGU | EuroPhenome 4.12E-5
Chst12
Chst12em1Marc
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MARC | IMPC 4.2E-5
Phactr1
Phactr1em1Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 4.35E-5
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage MRC Harwell | EuroPhenome 4.87E-5
Gtf2h2
Gtf2h2tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased KLRG1+ CD4 alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ KLRG1+ alpha beta T cell number WTSI | 3i 4.87E-5
Scaper
Scapertm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) differential count ICS | IMPC 4.91E-5
Zfp595
Zfp595tm1b(KOMP)Wtsi
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MRC Harwell | IMPC 5.05E-5
Xbp1
Xbp1tm1a(EUCOMM)Wtsi
HET Male postnatal decreased T cell number FACs Analysis | CD25+ percentage of CD4+ T cells HMGU | EuroPhenome 5.13E-5
Gpx7
Gpx7tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 5.43E-5
Coro1a
Coro1atm1.1(KOMP)Vlcg
HOM Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 5.56E-5
Ranbp1
Ranbp1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 5.57E-5
Arhgef12
Arhgef12tm1b(KOMP)Wtsi
HET Female postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 5.74E-5
Fkbp10
Fkbp10tm2a(EUCOMM)Wtsi
HET Male postnatal decreased mature B cell number FACs Analysis | Mature B cells IgD+ percentage ICS | EuroPhenome 5.77E-5
Tnfrsf1b
Tnfrsf1btm1a(EUCOMM)Wtsi
HOM Female postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage ICS | MGP 5.91E-5
Csmd1
Csmd1em1(IMPC)Wtsi
HOM Female Male postnatal decreased KLRG1+ CD8 alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD8+ KLRG1+ alpha beta T cell percentage WTSI | 3i 6.14E-5
Usp20
Usp20tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased KLRG1+ CD8 alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD8+ KLRG1+ alpha beta T cell percentage WTSI | 3i 6.22E-5
Nodal
Nodaltm1Rob
HET Male postnatal decreased B cell number FACs Analysis | B cell CD19+ percentage MRC Harwell | EuroPhenome 6.35E-5
Lef1
Lef1tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 6.77E-5
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage MRC Harwell | EuroPhenome 7.44E-5
Dtwd1
Dtwd1em1Marc
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MARC | IMPC 7.57E-5
Wrnip1
Wrnip1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage HMGU | EuroPhenome 7.68E-5
Avp
Avptm1b(EUCOMM)Wtsi
HET Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) count MRC Harwell | IMPC 7.88E-5
Wrnip1
Wrnip1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased CD8-positive, alpha-beta T cell number FACs Analysis | T cell CD8+ percentage HMGU | EuroPhenome 7.92E-5
Rida
Ridatm1a(KOMP)Wtsi
HOM Male postnatal decreased NK T cell number Whole blood peripheral blood leukocyte immunophenotyping | NKT cell number WTSI | 3i 8.42E-5
Nr1d2
Nr1d2tm1Dgen
HOM Male postnatal decreased CD4-positive, alpha beta T cell number FACs Analysis | T cell CD4+ percentage ICS | EuroPhenome 8.5E-5
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased mature B cell number FACs Analysis | Mature B cells IgD+ percentage HMGU | EuroPhenome 8.73E-5
4933434E20Rik
4933434E20Riktm1a(EUCOMM)Wtsi
HET Male postnatal decreased T cell number Whole blood peripheral blood leukocyte immunophenotyping | Total T cell percentage WTSI | 3i 8.89E-5
Clca1
Clca1em2Mbp
HOM Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count UC Davis | IMPC 9.14E-5
Trim21
Trim21em1(IMPC)Wtsi
HOM Female Male postnatal decreased mature B cell number Whole blood peripheral blood leukocyte immunophenotyping | IgD+ mature B cell percentage WTSI | 3i 9.52E-5
Slc16a4
Slc16a4tm2e(EUCOMM)Wtsi
HOM Female Male postnatal decreased KLRG1+ CD4 alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ KLRG1+ alpha beta T cell number WTSI | 3i 9.71E-5
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased T cell number FACs Analysis | T cell CD3+ percentage MRC Harwell | EuroPhenome 9.87E-5
Cep83
Cep83tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte differential count UC Davis | IMPC 9.9E-5
Got1
Got1tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased lymphocyte cell number Hematology | Lymphocyte cell count MRC Harwell | IMPC 9.96E-5
Itgae
Itgaetm1b(EUCOMM)Wtsi
HOM Male postnatal decreased large unstained cell number Hematology | Large Unstained Cell (LUC) count MRC Harwell | IMPC 9.97E-5

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