IMPC Gene variants with vertebral fusion
Total number of significant genotype-phenotype associations: 68
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Xbp1 Xbp1tm1a(EUCOMM)Wtsi |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-Ray |
ICS EuroPhenome |
3.68×10-21 | |
Ttc28 Ttc28tm1b(EUCOMM)Hmgu |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
TCP IMPC |
2.24×10-12 | |
Slc29a1 Slc29a1tm2b(NCOM)Mfgc |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
TCP IMPC |
3.43×10-10 | |
Cbx5 Cbx5tm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
2.57×10-09 | |
Cbx5 Cbx5tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
4.88×10-08 | |
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
1.67×10-07 | |
Wdr37 Wdr37tm1a(KOMP)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
1.67×10-07 | |
Ube2g1 Ube2g1tm1b(EUCOMM)Hmgu |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
RBRC IMPC |
2.60×10-07 | |
Il12a Il12atm1b(EUCOMM)Hmgu |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
MRC Harwell IMPC |
5.25×10-07 | |
Setd3 Setd3tm1.1(NCOM)Mfgc |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
TCP IMPC |
6.83×10-07 | |
Fgf20 Fgf20em1(IMPC)Ccpcz |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
CCP-IMG IMPC |
7.24×10-07 | |
Sirt3 Sirt3tm1b(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
MRC Harwell IMPC |
7.84×10-07 | |
Gna11 Gna11tm1b(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
MRC Harwell IMPC |
8.18×10-07 | |
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
MRC Harwell IMPC |
1.31×10-06 | |
Ankrd13a Ankrd13aGt(RRH308)Byg |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-Ray |
WTSI MGP |
1.94×10-06 | |
Pdss2 Pdss2tm1b(EUCOMM)Hmgu |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
MRC Harwell IMPC |
2.03×10-06 | |
Spred1 Spred1em1(IMPC)Ccpcz |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
CCP-IMG IMPC |
3.15×10-06 | |
Rnf168 Rnf168tm2b(EUCOMM)Hmgu |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
CCP-IMG IMPC |
4.07×10-06 | |
Fbn2 Fbn2em1(IMPC)Rbrc |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
RBRC IMPC |
5.23×10-06 | |
Fgf20 Fgf20em1(IMPC)Ccpcz |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
CCP-IMG IMPC |
5.60×10-06 | |
Ube2g1 Ube2g1tm1b(EUCOMM)Hmgu |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
RBRC IMPC |
5.70×10-06 | |
Asxl1 Asxl1tm1a(EUCOMM)Wtsi |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
6.98×10-06 | |
Ppp5c Ppp5ctm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI EuroPhenome |
6.98×10-06 | |
Cenpj Cenpjtm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
7.23×10-06 | |
Aff3 Aff3tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
7.64×10-06 | |
Slc25a4 Slc25a4tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
9.17×10-06 | |
Xndc1 Xndc1tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
9.17×10-06 | |
Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
1.10×10-05 | |
Fggy Fggytm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
1.15×10-05 | |
Gm13547 Gm13547tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
1.15×10-05 | |
Zscan2 Zscan2tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
1.15×10-05 | |
Gyg1 Gyg1tm1b(KOMP)Wtsi |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
BCM IMPC |
1.25×10-05 | |
Abca4 Abca4tm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
1.31×10-05 | |
Ushbp1 Ushbp1tm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
1.31×10-05 | |
Kat14 Kat14tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI EuroPhenome |
1.54×10-05 | |
Gbx1 Gbx1Gbx1 |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-Ray |
ICS EuroPhenome |
1.80×10-05 | |
Arpc2 Arpc2tm1a(EUCOMM)Wtsi |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
2.22×10-05 | |
Rhou Rhoutm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
2.29×10-05 | |
Dscc1 Dscc1tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
3.12×10-05 | |
Selenon Selenontm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
3.12×10-05 | |
Rlim Rlimem1(IMPC)Rbrc |
HEM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
RBRC IMPC |
3.45×10-05 | |
Mysm1 Mysm1tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-Ray |
WTSI EuroPhenome |
3.65×10-05 | |
Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
3.70×10-05 | |
Lyplal1 Lyplal1tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
3.92×10-05 | |
Os9 Os9tm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
3.92×10-05 | |
Sel1l Sel1ltm1e(KOMP)Wtsi |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
3.92×10-05 | |
Setd5 Setd5tm1a(EUCOMM)Wtsi |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
3.92×10-05 | |
Wdr37 Wdr37tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
3.92×10-05 | |
Pals2 Pals2em1(IMPC)Rbrc |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
RBRC IMPC |
4.49×10-05 | |
Tmem248 Tmem248tm1.1(KOMP)Vlcg |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
UC Davis IMPC |
4.79×10-05 | |
Tmc6 Tmc6tm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
5.02×10-05 | |
Spred1 Spred1em1(IMPC)Ccpcz |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
CCP-IMG IMPC |
5.27×10-05 | |
Ltbp1 Ltbp1tm1a(EUCOMM)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
5.49×10-05 | |
Slc25a21 Slc25a21tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI MGP |
5.49×10-05 | |
Gramd2a Gramd2aem1(IMPC)Tcp |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
TCP IMPC |
7.67×10-05 | |
Fbrsl1 Fbrsl1em1(IMPC)Tcp |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
TCP IMPC |
8.56×10-05 | |
Ppp1r42 Ppp1r42tm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
8.79×10-05 | |
Scn3b Scn3btm1a(KOMP)Wtsi |
HOM | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
WTSI IMPC |
8.79×10-05 | |
Bptf Bptfem1(IMPC)Bay |
HET | Early adult | vertebral fusion | Fusion of vertebrae X-ray |
BCM IMPC |
8.94×10-05 | |
Wac Wactm2b(EUCOMM)Wtsi |
HET | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
9.73×10-05 |