Phenotype: decreased circulating iron level

Definition less than the normal concentration of iron in the blood

Synonyms
  • hypoferremia
  • hypoferremia
  • reduced circulating iron level
  • reduced circulating iron level
  • decreased serum iron level
  • hypoferraemia
  • serum iron deficiency
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Related
Synonyms
Decreased serum iron

MP browserMP:0004151

Phenotype associations stats

1.11% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased circulating iron level (33/2975)

0.89% females (26/2907) 0.93% males (27/2902)

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Gene variants with decreased circulating iron level

Total number of significant genotype-phenotype associations: 53

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 1.79E-11
Cp
Cptm1b(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron JAX | IMPC 1.09E-10
Sfrp5
Sfrp5Q27STOP
HOM Male postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | EuroPhenome 1.62E-8
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | IMPC 1.64E-8
Ddhd1
Ddhd1tm1a(KOMP)Wtsi
HOM Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 1.84E-7
Trf
Trfem1(IMPC)Rbrc
HET Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron RBRC | IMPC 2.51E-7
Chn1
Chn1em1(IMPC)J
HET Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron JAX | IMPC 5.17E-7
Tmem167
Tmem167tm1a(EUCOMM)Hmgu
HET Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | MGP 5.34E-7
Otud7b
Otud7btm1b(EUCOMM)Wtsi
HET Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 1.41E-6
Fto
Ftotm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | EuroPhenome 3.23E-6
Mfsd2b
Mfsd2btm1a(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | MGP 3.73E-6
Evl
Evltm1b(KOMP)Wtsi
HOM Female postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | IMPC 3.85E-6
Rida
Ridatm1a(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 6.66E-6
Dusp1
Dusp1tm1(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | MGP 1.34E-5
Plcz1
Plcz1em1(IMPC)H
HOM Female postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | IMPC 1.34E-5
Cenpo
Cenpotm1b(KOMP)Mbp
HET Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron JAX | IMPC 1.72E-5
Parvb
Parvbtm1a(EUCOMM)Wtsi
HOM Male postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | MGP 1.83E-5
Ipo11
Ipo11tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron JAX | IMPC 1.83E-5
Bola2
Bola2tm1(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron MARC | IMPC 2.33E-5
Rhd
Rhdtm1e(EUCOMM)Wtsi
HOM Female postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | EuroPhenome 2.55E-5
Acap1
Acap1tm1.1(KOMP)Vlcg
HOM Female postnatal decreased circulating iron level Clinical Chemistry | Iron JAX | IMPC 4.14E-5
Kdm7a
Kdm7atm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 4.51E-5
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 4.68E-5
Kcne2
Kcne2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | EuroPhenome 5.38E-5
Sfxn3
Sfxn3tm1b(KOMP)Wtsi
HOM Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 6.13E-5
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron JAX | IMPC 6.94E-5
Fbxo11
Fbxo11tm2b(EUCOMM)Wtsi
HET Female postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | IMPC 7.35E-5
Leprot
Leprottm2a(KOMP)Wtsi
HOM Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 7.75E-5
Mast2
Mast2tm1a(KOMP)Wtsi
HOM Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 8.21E-5
Myo10
Myo10tm2(KOMP)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron WTSI | IMPC 8.47E-5
Mecom
MecomJbo
HET Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | EuroPhenome 9.14E-5
Gnao1
Gnao1tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | IMPC 9.16E-5
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased circulating iron level Clinical Chemistry | Iron MRC Harwell | EuroPhenome 9.92E-5

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