Phenotype: decreased heart rate variability

Definition
reduced variation of beat-to-beat intervals of the heart that occurs in conjunction with the respiratory cycle
Synonyms
reduced heart rate variation,  decreased respiratory sinus arrhythmia,  decreased HRV,  reduced HRV,  decreased heart rate variation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased heart rate variability

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Casq2
Casq2tm1b(KOMP)Wtsi
HET Early adult decreased heart rate variability HRV
Electrocardiogram (ECG)
TCP
IMPC
8.44×10-10
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate variability HRV
Electrocardiogram (ECG)
TCP
IMPC
4.82×10-06
Hdac1
Hdac1tm1b(EUCOMM)Wtsi
HET   Early adult decreased heart rate variability HRV
Electrocardiogram (ECG)
HMGU
IMPC
2.86×10-05
Tuba8
Tuba8em1(IMPC)J
HOM Late adult decreased heart rate variability HRV
Electrocardiogram (ECG)
JAX
IMPC
4.33×10-05
Ppp2r2b
Ppp2r2btm1b(KOMP)Wtsi
HOM   Early adult decreased heart rate variability HRV
Electrocardiogram (ECG)
TCP
IMPC
5.19×10-05
Drc7
Drc7em1(IMPC)J
HOM Late adult decreased heart rate variability HRV
Electrocardiogram (ECG)
JAX
IMPC
5.22×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.25% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart rate variability (6/2432)

0.12% females (3/2407) 0.04% males (1/2408)

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