Phenotype: increased kidney weight

Definition greater weight of the organs responsible for urine secretion

MP browserMP:0003917

Phenotype associations stats

3.35% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased kidney weight (6/179)

2.84% females (5/176) 2.92% males (5/171)

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Gene variants with increased kidney weight

Total number of significant genotype-phenotype associations: 10

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Abcc2
Abcc2tm2b(KOMP)Wtsi
HOM Female Male postnatal increased kidney weight Organ Weight | Left kidney MRC Harwell | IMPC 2.11E-12
Grm6
Grm6tm1b(EUCOMM)Wtsi
HOM Female postnatal increased kidney weight Organ Weight | Right kidney MRC Harwell | IMPC 9.08E-7
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Male postnatal increased kidney weight Organ Weight | Right kidney MRC Harwell | IMPC 2.64E-5
Klf7
Klf7tm1b(EUCOMM)Hmgu
HET Female Male postnatal increased kidney weight Organ Weight | Left kidney MRC Harwell | IMPC 3.04E-5
Hipk2
Hipk2tm2b(EUCOMM)Hmgu
HET Female Male postnatal increased kidney weight Organ Weight | Left kidney MRC Harwell | IMPC 3.05E-5
Ube2e2
Ube2e2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased kidney weight Organ Weight | Left kidney MRC Harwell | IMPC 8.63E-5

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