Phenotype: shortened QT interval

Definition
decrease in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time, and is measured from the beginning of the QRS complex to the end of the T wave
Synonyms
decreased QT interval,  reduced QT interval,  short QT
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened QT interval

Total number of significant genotype-phenotype associations: 16

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Dnajc5b
Dnajc5btm1b(EUCOMM)Hmgu
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
2.78×10-08
Dhx15
Dhx15em1(IMPC)Tcp
HET Early adult shortened QT interval QT
Electrocardiogram (ECG)
TCP
IMPC
1.54×10-05
Igfbp3
Igfbp3tm1b(KOMP)Wtsi
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.55×10-05
Ube4a
Ube4aem1(IMPC)Tcp
HOM   Early adult shortened QT interval QT
Electrocardiogram (ECG)
TCP
IMPC
2.97×10-05
Gcsh
Gcshem1(IMPC)H
HET Early adult shortened QT interval QT
Electrocardiogram (ECG)
MRC Harwell
IMPC
3.15×10-05
Casz1
Casz1tm1b(EUCOMM)Hmgu
HET   Early adult shortened QT interval QT
Electrocardiogram (ECG)
MRC Harwell
IMPC
3.39×10-05
Cdh13
Cdh13tm1b(EUCOMM)Hmgu
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
3.79×10-05
Usp35
Usp35em1(IMPC)J
HOM   Early adult shortened QT interval QT
Electrocardiogram (ECG)
JAX
IMPC
4.35×10-05
Pierce2
Pierce2em1(IMPC)H
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
MRC Harwell
IMPC
4.51×10-05
Stambp
Stambptm1b(EUCOMM)Hmgu
HET Early adult shortened QT interval QT
Electrocardiogram (ECG)
MRC Harwell
IMPC
5.06×10-05
Atp10a
Atp10aem1(IMPC)Tcp
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
TCP
IMPC
5.58×10-05
Pcdh18
Pcdh18tm1.1(KOMP)Vlcg
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
5.83×10-05
Morc4
Morc4em1(IMPC)Mbp
HEM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
6.10×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
6.89×10-05
Setd3
Setd3tm1.1(NCOM)Mfgc
HOM   Early adult shortened QT interval QT
Electrocardiogram (ECG)
TCP
IMPC
8.50×10-05
Ppp2r5c
Ppp2r5cem1(IMPC)Mbp
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
9.87×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.37% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened QT interval (16/4315)

0.12% females (5/4293) 0.16% males (7/4291)



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