Phenotype: decreased macrophage cell number

Definition
fewer than the normal numbers of macrophages
Synonyms
reduced macrophage count,  reduced macrophage cell number,  decreased macrophage count
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased macrophage cell number

Total number of significant genotype-phenotype associations: 4

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM   Early adult decreased macrophage cell number Macrophages - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Gmds
Gmdstm1a(KOMP)Wtsi
HOM   Early adult decreased macrophage cell number Macrophages - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Spink14
Spink14tm1e(KOMP)Wtsi
HOM   Early adult decreased macrophage cell number Macrophages - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Spink6
Spink6em1(IMPC)Ccpcz
HOM Early adult decreased macrophage cell number RP Macrophage (CD19- CD11c-)
Immunophenotyping
CCP-IMG
IMPC
2.73×10-08

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 The way we measure

 Phenotype associations stats

4.82% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased macrophage cell number (4/83)

0.00% females (0/76) 1.35% males (1/74)

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