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Phenotype: increased circulating glycerol level

Definition
elevated blood level of trihydroxy sugar alcohols that are precursors for synthesis of triacylglycerols, and of phospholipids and cellular glucose in the liver and adipose tissue; fat catabolism results in the release of glycerol and fatty acids into the bloodstream to be used as an energy source
Synonyms
hyperglycerolaemia,  hyperglycerolemia
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased circulating glycerol level

Total number of significant genotype-phenotype associations: 20

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Camsap3
Camsap3tm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 2.66×10-08
Dusp3
Dusp3tm1b(KOMP)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 3.32×10-08
Lgals7
Lgals7tm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 1.44×10-07
Dgki
Dgkiem1(IMPC)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 1.94×10-06
Ccdc18
Ccdc18tm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 3.10×10-06
Zmym4
Zmym4em1(IMPC)Wtsi 		HET Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 3.20×10-06
Clpp
Clpptm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 3.95×10-06
Trmt10a
Trmt10atm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
MGP		 8.33×10-06
Zfp763
Zfp763em1(IMPC)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 8.60×10-06
Trmo
Trmotm1a(EUCOMM)Wtsi 		HOM   Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
MGP		 1.54×10-05
Rc3h2
Rc3h2tm1a(KOMP)Wtsi 		HET Early adult increased circulating glycerol level Glycerol
Fasted Clinical Chemistry		 HMGU
EuroPhenome		 1.67×10-05
Actr6
Actr6tm1a(EUCOMM)Wtsi 		HET Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 1.72×10-05
Gnasas1
Gnasas1tm2.1Jop 		HET Early adult increased circulating glycerol level Glycerol
Fasted Clinical Chemistry		 MRC Harwell
EuroPhenome		 2.22×10-05
Ift25
Ift25tm1a(EUCOMM)Wtsi 		HET Early adult increased circulating glycerol level Glycerol
Fasted Clinical Chemistry		 WTSI
EuroPhenome		 3.23×10-05
Smyd4
Smyd4tm1a(EUCOMM)Wtsi 		HOM   Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
MGP		 3.27×10-05
Aspm
Aspmtm1a(KOMP)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 4.11×10-05
Gm28050
Gm28050tm1.1(NCC)WCS 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 5.81×10-05
Glg1
Glg1tm1a(KOMP)Wtsi 		HET Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
IMPC		 8.29×10-05
Stx8
Stx8tm2a(EUCOMM)Wtsi 		HOM Early adult increased circulating glycerol level Glycerol
Clinical Chemistry		 WTSI
MGP		 8.37×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Clinical Blood Chemistry
Clinical Chemistry
Fasted Bleed
Fasted Clinical Chemistry
Terminal Bleed

 Phenotype associations stats

1.10% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased circulating glycerol level (19/1720)

0.41% females (7/1715) 0.64% males (11/1709)

Select a parameter    



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