Phenotype: decreased hemoglobin content

Definition decrease in the total hemoglobin content in the circulating blood

Synonyms
  • reduced haemoglobin content
  • reduced haemoglobin content
  • reduced hemoglobin content
  • reduced hemoglobin content
  • decreased haemoglobin content
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MP browserMP:0002874

Phenotype associations stats

1.73% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased hemoglobin content (71/4109)

1.37% females (56/4084) 1.54% males (63/4084)

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Gene variants with decreased hemoglobin content

Total number of significant genotype-phenotype associations: 126

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Mul1
Mul1em1(IMPC)H
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 0.0
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin WTSI | EuroPhenome 2.95E-33
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 9.35E-27
Gna11
Gna11tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 7.77E-25
Gna11
Gna11tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 4.42E-24
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin TCP | IMPC 3.91E-21
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 7.02E-19
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin TCP | IMPC 5.46E-18
Mecom
MecomJbo
HET Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 1.95E-17
Comt
Comttm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 2.65E-13
Prkab1
Prkab1tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 1.1E-12
Etaa1
Etaa1em1(IMPC)Marc
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MARC | IMPC 2.21E-11
Tmem189
Tmem189tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 3.28E-11
Fbxo11
Fbxo11tm2b(EUCOMM)Wtsi
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 9.87E-11
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 1.1E-10
Smurf2
Smurf2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.69E-10
Epas1
Epas1tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 6.37E-10
Atp6v1b2
Atp6v1b2tm1b(KOMP)Wtsi
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin TCP | IMPC 9.38E-9
Gigyf2
Gigyf2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.32E-8
Plekhm2
Plekhm2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 3.53E-8
Rreb1
Rreb1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 6.3E-8
Mta3
Mta3tm3a(KOMP)Wtsi
HET Female Male postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration WTSI | EuroPhenome 6.43E-8
Thrb
Thrbtm2a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 6.45E-8
Cp
Cptm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin JAX | IMPC 6.67E-8
Lyn
Lyntm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.2E-7
Emcn
Emcnem1(IMPC)Wtsi
HOM Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 1.78E-7
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 2.39E-7
Klhl3
Klhl3tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 2.55E-7
Mysm1
Mysm1tm1a(KOMP)Wtsi
HET Female Male postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration MRC Harwell | EuroPhenome 3.73E-7
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 3.97E-7
Asxl1
Asxl1tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 5.92E-7
Zfp13
Zfp13tm1a(EUCOMM)Hmgu
HOM Male postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 5.98E-7
Dpy19l3
Dpy19l3tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin ICS | EuroPhenome 7.15E-7
Kdm2b
Kdm2bem1(IMPC)Marc
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MARC | IMPC 8.04E-7
Stard3
Stard3
HOM Female Male postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 8.35E-7
Kdm4c
Kdm4ctm1a(KOMP)Wtsi
HOM Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 1.18E-6
Usmg5
Usmg5tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.19E-6
Smurf2
Smurf2tm1b(EUCOMM)Wtsi
HET Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 3.25E-6
Cpeb4
Cpeb4tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin HMGU | IMPC 4.77E-6
Atp5a1
Atp5a1tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 5.73E-6
Ap4e1
Ap4e1tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 6.47E-6
Rbm11
Rbm11em1(IMPC)Marc
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MARC | IMPC 8.22E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin RBRC | IMPC 8.8E-6
Tmem161b
Tmem161btm2b(EUCOMM)Hmgu
HET Female postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 9.27E-6
Pknox1
Pknox1Gt(EUCJ0079d10)Hmgu
HET Female postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration HMGU | EuroPhenome 1.01E-5
Gbx1
Gbx1
HOM Female postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 1.03E-5
Camsap3
Camsap3tm1a(EUCOMM)Wtsi
HET Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 1.34E-5
Adcy3
Adcy3tm1a(EUCOMM)Wtsi
HET Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 1.38E-5
Chd2
Chd2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin TCP | IMPC 1.42E-5
Irgm1
Irgm1em1(IMPC)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 1.59E-5
Nagk
Nagktm1b(EUCOMM)Hmgu
HOM Male postnatal decreased hemoglobin content Hematology | Hemoglobin MRC Harwell | IMPC 1.66E-5
Scarf2
Scarf2tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 1.75E-5
Chd1
Chd1tm1b(KOMP)Wtsi
HET Female postnatal decreased hemoglobin content Hematology | Hemoglobin TCP | IMPC 1.99E-5
Dock10
Dock10tm1a(EUCOMM)Hmgu
HOM Female postnatal decreased hemoglobin content Haematology | Haemoglobin HMGU | EuroPhenome 2.03E-5
Asns
Asnstm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 2.63E-5
Umod
Umodurehr4
HOM Female Male postnatal decreased hemoglobin content Haematology | Haemoglobin HMGU | EuroPhenome 2.82E-5
Ufm1
Ufm1em1(IMPC)Marc
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin MARC | IMPC 2.85E-5
Rnase1
Rnase1em5(IMPC)Tcp
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin TCP | IMPC 3.01E-5
Aldh3a2
Aldh3a2tm1a(EUCOMM)Wtsi
HOM Male postnatal decreased hemoglobin content Haematology | Haemoglobin ICS | EuroPhenome 3.3E-5
Cln6
Cln6tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased hemoglobin content Hematology | Hemoglobin TCP | IMPC 3.64E-5
Dph6
Dph6tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 4.19E-5
Hprt
Hprttm1a(EUCOMM)Hmgu
HOM Female postnatal decreased hemoglobin content Haematology | Haemoglobin HMGU | EuroPhenome 4.65E-5
Ogfod1
Ogfod1tm1a(KOMP)Wtsi
HOM Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 4.67E-5
Fkbp10
Fkbp10tm2a(EUCOMM)Wtsi
HET Female postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 5.23E-5
Zzz3
Zzz3tm1a(EUCOMM)Wtsi
HET Female postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 5.8E-5
Retreg3
Retreg3tm2a(EUCOMM)Wtsi
HOM Male postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration ICS | EuroPhenome 5.93E-5
Cntn6
Cntn6em1(IMPC)Wtsi
HOM Male postnatal decreased hemoglobin content Hematology | Hemoglobin WTSI | IMPC 5.99E-5
Eps15
Eps15tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 6.57E-5
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Male postnatal decreased hemoglobin content Haematology | Haemoglobin MRC Harwell | EuroPhenome 6.94E-5
Ndufs3
Ndufs3tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | EuroPhenome 7.2E-5
Adgb
Adgbem1(IMPC)Mbp
HET Female Male postnatal decreased hemoglobin content Hematology | Hemoglobin UC Davis | IMPC 7.36E-5
Ncaph
Ncaphtm1a(EUCOMM)Wtsi
HET Male postnatal decreased hemoglobin content Haematology test | Haemoglobin WTSI | MGP 7.51E-5
Slc12a1
Slc12a1urehr3
HOM Male postnatal decreased hemoglobin content Haematology (GMC) | Hemoglobin HMGU | EuroPhenome 9.01E-5
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration HMGU | EuroPhenome 9.22E-5
Eef2kmt
Eef2kmttm1e(EUCOMM)Wtsi
HOM Male postnatal decreased hemoglobin content Haematology | Mean cell haemoglobin concentration HMGU | EuroPhenome 9.78E-5

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