Definition
lower than normal levels of the fatty acids which occur in plasma as a result of lipolysis in adipose tissue or when plasma triacylglycerols are taken into tissues
Synonyms
reduced circulating free fatty acid level,
reduced circulating non-esterified fatty acids level,
decreased unesterified fatty acids level,
decreased UFA level,
decreased circulating free fatty acid level,
reduced FFA level,
decreased FFA level,
reduced unesterified fatty acids level,
decreased circulating non-esterified fatty acids level,
reduced UFA level
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased circulating free fatty acids level
Total number of significant genotype-phenotype associations: 44
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Mindy1 Mindy1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
6.04×10-09 | |
| Cenpo Cenpotm1b(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
3.15×10-08 | |
| Diaph3 Diaph3tm1b(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
2.14×10-07 | |
| Rint1 Rint1tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
3.48×10-07 | |
| Cc2d1b Cc2d1btm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
3.70×10-07 | |
| Ap4e1 Ap4e1em1(IMPC)J |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
6.42×10-07 | |
| Plcg2 Plcg2Ali14 |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
HMGU EuroPhenome |
7.50×10-07 | |
| Cc2d1b Cc2d1btm1a(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
9.20×10-07 | |
| Dbn1 Dbn1tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
1.10×10-06 | |
| Kif26b Kif26btm2b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
1.35×10-06 | |
| Cpgi15344 Cpgi15344tm1.1(NCC)WCS |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.41×10-06 | |
| Cyb5d1 Cyb5d1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.33×10-06 | |
| Rpa1 Rpa1tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.69×10-06 | |
| Snf8 Snf8tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell MGP |
4.56×10-06 | |
| Dop1b Dop1btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
4.81×10-06 | |
| Bloc1s2 Bloc1s2tm1.1(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
5.23×10-06 | |
| Dpy19l3 Dpy19l3tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
ICS EuroPhenome |
5.71×10-06 | |
| Chn1 Chn1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
6.66×10-06 | |
| Tpgs2 Tpgs2tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.77×10-06 | |
| Hspb3 Hspb3tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.88×10-06 | |
| Mtarc2 Mtarc2tm2a(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
ICS EuroPhenome |
9.70×10-06 | |
| Rhd Rhdtm1e(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
1.31×10-05 | |
| Hmx3 Hmx3tm1Ebo |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI MGP |
1.95×10-05 | |
| Resp18 Resp18tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
2.41×10-05 | |
| Gnasas1 Gnasas1tm2.1Jop |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell EuroPhenome |
2.44×10-05 | |
| Ska2 Ska2tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
2.65×10-05 | |
| Arhgef4 Arhgef4tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
HMGU EuroPhenome |
2.65×10-05 | |
| Entpd1 Entpd1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell EuroPhenome |
2.94×10-05 | |
| Osm Osmtm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.20×10-05 | |
| Prep Preptm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.65×10-05 | |
| Krt7 Krt7tm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
3.89×10-05 | |
| Cpgi5563 Cpgi5563tm1.1(NCC)WCS |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
4.70×10-05 | |
| Ceacam16 Ceacam16tm1.1(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
5.22×10-05 | |
| Irf8 Irf8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
5.40×10-05 | |
| Pycr1 Pycr1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
6.13×10-05 | |
| Palb2 Palb2tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.40×10-05 | |
| Mmp8 Mmp8tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.58×10-05 | |
| Rnf169 Rnf169tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell EuroPhenome |
7.73×10-05 | |
| Mier1 Mier1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
WTSI EuroPhenome |
8.25×10-05 | |
| Rfc1 Rfc1tm1b(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
8.44×10-05 |