Definition
a greater than average point at which thermal pain sensation is first detectable
Synonyms
thermal hypoalgesia,
decreased thermal nociception,
prolonged latency in hot plate test
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased thermal nociceptive threshold
Total number of significant genotype-phenotype associations: 18
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Mir96 Mir96Dmdo |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI MGP |
3.70×10-22 | |
| Zfp106 Zfp106tm1a(KOMP)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI EuroPhenome |
4.44×10-16 | |
| Mysm1 Mysm1tm1a(KOMP)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI EuroPhenome |
1.56×10-15 | |
| Bbx Bbxtm1a(EUCOMM)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI EuroPhenome |
1.22×10-10 | |
| Whrn Whrntm1a(EUCOMM)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI MGP |
2.30×10-06 | |
| Rars1 Rars1tm1a(EUCOMM)Wtsi |
HET | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI MGP |
3.40×10-06 | |
| Myo7a Myo7aHdb |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI MGP |
9.18×10-06 | |
| Dnase2b Dnase2btm1a(EUCOMM)Hmgu |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
MRC Harwell EuroPhenome |
1.76×10-05 | |
| Cdca8 Cdca8tm1a(KOMP)Wtsi |
HET | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI MGP |
2.99×10-05 | |
| Kmt5b Kmt5btm1a(KOMP)Wtsi |
HET | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI MGP |
3.90×10-05 | |
| Tecpr2 Tecpr2em1(IMPC)J |
HOM | Early adult | increased thermal nociceptive threshold | Baseline: latency to withdrawal Hargreaves Test |
JAX pwg |
6.19×10-05 | |
| Mta1 Mta1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI EuroPhenome |
7.67×10-05 | |
| Golm1 Golm1Gt(EUC0047a08)Hmgu |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
HMGU EuroPhenome |
7.83×10-05 | |
| Spns2 Spns2tm1a(KOMP)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI EuroPhenome |
8.65×10-05 | |
| Rapgefl1 Rapgefl1tm1a(KOMP)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI MGP |
9.39×10-05 | |
| Rad18 Rad18tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI EuroPhenome |
9.77×10-05 | |
| Tpm1 Tpm1tm1a(EUCOMM)Wtsi |
HET | Early adult | increased thermal nociceptive threshold | Time of first response Hot Plate |
WTSI EuroPhenome |
9.80×10-05 |