Phenotype: abnormal embryo turning

Definition
atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage during which the curvature of the entire trunk region is normally reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region
Synonyms
abnormal embryonic axial rotation,  Abnormal Turning of Embryo
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal embryo turning

Total number of significant genotype-phenotype associations: 148

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Actr5
Actr5tm2b(EUCOMM)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Alg8
Alg8em1(IMPC)J
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Ankmy2
Ankmy2em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Asf1a
Asf1atm1b(KOMP)Wtsi
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Atp1b1
Atp1b1em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Bicc1
Bicc1em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Bmp4
Bmp4tm1b(EUCOMM)Hmgu
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Cars2
Cars2em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Cdk8
Cdk8tm1b(EUCOMM)Hmgu
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
ICS
IMPC
0.00
Ckap5
Ckap5tm2b(EUCOMM)Hmgu
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Clcc1
Clcc1tm1b(KOMP)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Cmtr2
Cmtr2tm1.1(KOMP)Vlcg
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Csk
Csktm2b(EUCOMM)Hmgu
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ctbp2
Ctbp2em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Dbn1
Dbn1em2(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Ddx6
Ddx6em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Dennd1a
Dennd1aem1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Dhx29
Dhx29tm1.1(KOMP)Vlcg
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Diaph3
Diaph3tm1b(KOMP)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Dppa1
Dppa1tm1b(KOMP)Wtsi
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Dsp
Dspem1(IMPC)Mbp
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Dsp
Dspem1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Ehbp1
Ehbp1em1(IMPC)J
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Eloa
Eloaem1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Faf2
Faf2em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Glmn
Glmnem1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Got2
Got2em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Greb1l
Greb1lem1(IMPC)J
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Hyls1
Hyls1em1(IMPC)Tcp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Ift172
Ift172tm2b(EUCOMM)Hmgu
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ift43
Ift43tm1b(EUCOMM)Hmgu
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ift52
Ift52em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ift52
Ift52em1(IMPC)Bay
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ift88
Ift88tm1.1(KOMP)Vlcg
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Ints10
Ints10tm1b(KOMP)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Ipo9
Ipo9em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Isyna1
Isyna1em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Junb
Junbtm1b(EUCOMM)Hmgu
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Krit1
Krit1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Mdh2
Mdh2em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Myrf
Myrfem1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Nadk2
Nadk2em1(IMPC)J
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Ndufb5
Ndufb5em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ndufs7
Ndufs7tm1b(EUCOMM)Hmgu
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Nog
Nogem1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Nr6a1
Nr6a1tm1b(EUCOMM)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Nsmce2
Nsmce2em1(IMPC)Bay
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Nsmce2
Nsmce2em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Opa1
Opa1em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Pcgf1
Pcgf1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Pcnp
Pcnpem1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Pdhb
Pdhbem1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Phgdh
Phgdhtm1b(KOMP)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
KMPC
IMPC
0.00
Pibf1
Pibf1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Pigq
Pigqtm2b(EUCOMM)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Pole2
Pole2em1(IMPC)Mbp
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Ppp1r35
Ppp1r35tm1.1(KOMP)Vlcg
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Psmg1
Psmg1tm1b(KOMP)Wtsi
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Rad1
Rad1tm1b(KOMP)Wtsi
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Rad9a
Rad9atm1.1(KOMP)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Rfc1
Rfc1tm1b(KOMP)Mbp
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Rgl1
Rgl1em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Romo1
Romo1em1(IMPC)Kmpc
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
KMPC
IMPC
0.00
Sfmbt2
Sfmbt2em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Slc30a9
Slc30a9em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Smo
Smotm1b(KOMP)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Srd5a3
Srd5a3tm1b(EUCOMM)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Tbx20
Tbx20em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Tead1
Tead1tm1b(KOMP)Wtsi
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Tedc2
Tedc2em1(IMPC)J
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Tgds
Tgdsem1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Tlk2
Tlk2em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Tmem70
Tmem70em2(IMPC)Bay
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Tmem70
Tmem70em2(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Traf3ip1
Traf3ip1em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ubtf
Ubtfem1(IMPC)Mbp
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Uggt1
Uggt1em1(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Uqcc3
Uqcc3em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Vcan
Vcanem2(IMPC)Mbp
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Vps54
Vps54em1(IMPC)Bay
HET E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Zmym2
Zmym2em1(IMPC)Bay
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Zmym2
Zmym2em1(IMPC)J
HOM E9.5 abnormal embryo turning Embryo turning
Gross Morphology Embryo E9.5
JAX
IMPC
0.00

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 The way we measure

 Phenotype associations stats

10.25% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal embryo turning (77/751)

9.09% females (72/792) 8.48% males (67/790)

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