Phenotype: impaired righting response

Phenotype associations stats

0.70% of tested genes with null mutations on a B6N genetic background have a phenotype association to impaired righting response (30/4312)

0.54% females (23/4299) 0.42% males (18/4285)

Gene variants with impaired righting response

Total number of significant genotype-phenotype associations: 42

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Ush1c
Ush1ctm1a(KOMP)Wtsi
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting reflex WTSI | IMPC 1.59E-22
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting MRC Harwell | IMPC 5.07E-21
Mir96
Mir96tm3.2(IMPC)Wtsi
HOM Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting reflex WTSI | IMPC 3.98E-20
Cyba
Cybatm1a(EUCOMM)Wtsi
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting reflex WTSI | IMPC 9.47E-17
Chn1
Chn1tm1.1(KOMP)Vlcg
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 2.67E-16
Cdh23
Cdh23tm2b(EUCOMM)Wtsi
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting reflex WTSI | IMPC 7.91E-14
Prpf6
Prpf6tm1.1(KOMP)Vlcg
HET Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 2.21E-11
Hsd17b1
Hsd17b1tm1.1(KOMP)Vlcg
HOM Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 8.71E-11
Pfdn6
Pfdn6tm1.1(KOMP)Vlcg
HET Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 2.37E-9
Myo7a
Myo7atm1a(EUCOMM)Wtsi
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting reflex WTSI | IMPC 2.63E-8
Pkp4
Pkp4tm1b(EUCOMM)Wtsi
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 3.32E-7
Epha10
Epha10tm1.1(KOMP)Vlcg
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 6.58E-7
Hapln1
Hapln1tm1.1(KOMP)Mbp
HET Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 6.58E-7
Slc8b1
Slc8b1em1(IMPC)J
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 6.58E-7
Epgn
Epgntm1b(KOMP)Wtsi
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 1.17E-6
Postn
Postntm1.1(KOMP)Vlcg
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 3.5E-6
Avp
Avptm1b(EUCOMM)Wtsi
HET Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting MRC Harwell | IMPC 1.03E-5
Mcub
Ccdc109btm1b(KOMP)Mbp
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting MRC Harwell | IMPC 1.03E-5
Fgf7
Fgf7tm1e.1(EUCOMM)Hmgu
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting MRC Harwell | IMPC 1.03E-5
Gnao1
Gnao1tm1b(EUCOMM)Hmgu
HET Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting MRC Harwell | IMPC 1.03E-5
Stat1
Stat1tm2b(EUCOMM)Wtsi
HOM Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting ICS | IMPC 1.58E-5
Mir96
Mir96tm2.2(IMPC)Wtsi
HOM Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting reflex WTSI | IMPC 2.74E-5
Ipp
Ipptm1.1(KOMP)Vlcg
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 4.74E-5
Rnf25
Rnf25tm1.1(KOMP)Vlcg
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 4.74E-5
Serpinb5
Serpinb5tm1b(KOMP)Wtsi
HOM Female Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 4.74E-5
Vsig4
Vsig4tm1b(EUCOMM)Hmgu
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 4.74E-5
Ydjc
Ydjctm1.1(KOMP)Vlcg
HOM Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 4.74E-5
Fastkd5
Fastkd5em1(IMPC)J
HOM Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 7.28E-5
Zfp689
Zfp689tm1.1(KOMP)Vlcg
HOM Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting JAX | IMPC 7.28E-5
Klf7
Klf7tm1b(EUCOMM)Hmgu
HET Female postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting MRC Harwell | IMPC 8.23E-5
Odf3l2
Odf3l2tm1.1(KOMP)Vlcg
HET Male postnatal impaired righting response Combined SHIRPA and Dysmorphology | Contact righting UC Davis | IMPC 8.76E-5

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