Phenotype: limb grasping

Definition mice clasp front and/or hind feet almost immediately upon being lifted by tail

Synonyms
  • abnormal clutching reflex
  • abnormal clutching reflex
  • grasping reflex
  • grasping reflex
  • hindlimb extension reflex
  • limb clasping
  • hind limb extension reflex
  • limb clamping
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MP browserMP:0001513

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Phenotype associations stats

1.07% of tested genes with null mutations on a B6N genetic background have a phenotype association to limb grasping (42/3927)

0.54% females (21/3901) 0.77% males (30/3907)

Gene variants with limb grasping

Total number of significant genotype-phenotype associations: 54

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Elovl6
Elovl6tm1b(EUCOMM)Hmgu
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 0.0
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.38E-22
Grm7
Grm7em2H
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.49E-16
Frrs1l
Frrs1ltm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.17E-13
Atn1
Atn1tm1b(EUCOMM)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 9.09E-13
Ngfr
Ngfrtm1b(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 9.09E-13
Il15
Il15tm1b(EUCOMM)Hmgu
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.99E-10
Arl6ip1
Arl6ip1tm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.02E-10
Aspa
Aspatm1b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp HMGU | IMPC 1.18E-9
Sema3f
Sema3ftm1b(EUCOMM)Hmgu
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.47E-9
2810408A11Rik
2810408A11Riktm1a(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 5.47E-9
Vgf
Vgfem1H
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.58E-8
Adipor2
Adipor2tm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.62E-8
Rpe65
Rpe65tm1a(EUCOMM)Hmgu
HOM Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 4.11E-8
Ptpn20
Ptpn20tm1b(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 1.28E-7
Kcnj3
Kcnj3tm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 2.38E-7
Rab18
Rab18Gt(EUCE0233a03)Hmgu
HET Female Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 3.55E-7
Rab18
Rab18Gt(EUCE0233a03)Hmgu
HOM Female Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 3.55E-7
Wdr47
Wdr47tm1a(EUCOMM)Wtsi
HOM Female postnatal limb grasping Modified SHIRPA | Limb Grasping WTSI | EuroPhenome 4.43E-7
Abcc5
Abcc5em1H
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.17E-6
Trpm1
Trpm1tm1b(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.17E-6
Ankib1
Ankib1tm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.28E-6
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.28E-6
Fgf2
Fgf2tm1b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.28E-6
Ndrg4
Ndrg4tm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.28E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.28E-6
Ube2b
Ube2btm1b(EUCOMM)Wtsi
HET Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.28E-6
Ube2b
Ube2btm1b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.28E-6
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.86E-6
Riiad1
Riiad1tm1b(KOMP)Wtsi
HET Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 6.44E-6
Gramd1c
Gramd1ctm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 6.46E-6
Vti1a
Vti1atm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 8.71E-6
Trpc3
Trpc3Mwk
HET Female postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 1.28E-5
Sorl1
Sorl1tm1b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.63E-5
Tmem63b
Tmem63btm1b(EUCOMM)Wtsi
HET Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp ICS | IMPC 3.24E-5
Mecom
MecomJbo
HET Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 3.97E-5
Shh
Shhtm1Chg
HET Female Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 5.19E-5
Rab15
Rab15tm1a(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasping WTSI | IMPC 5.77E-5
Slc41a3
Slc41a3tm1a(KOMP)Wtsi
HOM Female postnatal limb grasping Modified SHIRPA | Limb Grasping WTSI | EuroPhenome 6.89E-5
2700097O09Rik
2700097O09Riktm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 7.53E-5
Tmem256
Tmem256tm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 7.53E-5
Slitrk1
Slitrk1tm1.1(KOMP)Vlcg
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 7.57E-5
Ush1c
Ush1ctm1a(KOMP)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasping WTSI | IMPC 7.69E-5
Ppm1a
Ppm1atm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 8.78E-5

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