Phenotype: limb grasping

Phenotype associations stats

1.17% of tested genes with null mutations on a B6N genetic background have a phenotype association to limb grasping (53/4535)

0.73% females (33/4503) 0.80% males (36/4497)

Gene variants with limb grasping

Total number of significant genotype-phenotype associations: 70

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Elovl6
Elovl6tm1b(EUCOMM)Hmgu
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 0.0
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 7.41E-23
Pycr2
Pycr2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasping WTSI | IMPC 2.94E-18
Grm7
Grm7em1(IMPC)H
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 4.15E-17
Frrs1l
Frrs1ltm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 4.74E-14
Atn1
Atn1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.52E-13
Ngfr
Ngfrtm1b(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.52E-13
Bach2
Bach2tm1b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp HMGU | IMPC 2.22E-11
Il15
Il15tm1b(EUCOMM)Hmgu
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 6.61E-11
Arl6ip1
Arl6ip1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 9.36E-11
Sema3f
Sema3ftm1b(EUCOMM)Hmgu
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 6.86E-10
Aspa
Aspatm1b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp HMGU | IMPC 1.15E-9
2810408A11Rik
2810408A11Riktm1a(EUCOMM)Wtsi
HOM Female Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 5.47E-9
Vgf
Vgfem1(IMPC)H
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.03E-8
Adipor2
Adipor2tm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.38E-8
Rpe65
Rpe65tm1a(EUCOMM)Hmgu
HOM Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 4.11E-8
Ptpn20
Ptpn20tm1b(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 6.31E-8
Kcnj3
Kcnj3tm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 2.24E-7
Hecw1
Hecw1tm2b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 3.01E-7
Rab18
Rab18Gt(EUCE0233a03)Hmgu
HET Female Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 3.55E-7
Abcc5
Abcc5em1(IMPC)H
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.04E-6
Trpm1
Trpm1tm1b(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.04E-6
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 1.85E-6
Ankib1
Ankib1tm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.06E-6
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.06E-6
Fgf2
Fgf2tm1b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.06E-6
Ndrg4
Ndrg4tm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.06E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.06E-6
Ube2b
Ube2btm1b(EUCOMM)Wtsi
HET Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 2.06E-6
Riiad1
Riiad1tm1b(KOMP)Wtsi
HET Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 3.5E-6
Gramd1c
Gramd1ctm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 4.51E-6
Thra
Thratm1b(EUCOMM)Wtsi
HET Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp ICS | IMPC 5.09E-6
Adarb2
Adarb2em1(IMPC)Tcp
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp TCP | IMPC 7.14E-6
Shank2
Shank2em2(IMPC)Rbrc
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp RBRC | IMPC 8.02E-6
Vti1a
Vti1atm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 8.28E-6
Trpc3
Trpc3Mwk
HET Female postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 1.28E-5
Tmem63b
Tmem63btm1b(EUCOMM)Wtsi
HET Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp ICS | IMPC 2.1E-5
Rab15
Rab15tm1a(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasping WTSI | IMPC 3.28E-5
Mecom
MecomJbo
HET Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 3.97E-5
Ush1c
Ush1ctm1a(KOMP)Wtsi
HOM Female Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasping WTSI | IMPC 4.14E-5
Shh
Shhtm1Chg
HET Female Male postnatal limb grasping Modified SHIRPA | Limb grasping MRC Harwell | EuroPhenome 5.19E-5
Ppm1a
Ppm1atm1b(EUCOMM)Hmgu
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 6.1E-5
Gbx1
Gbx1tm1b(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 6.99E-5
2700097O09Rik
2700097O09Riktm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 7.21E-5
Tmem256
Tmem256tm1.1(KOMP)Vlcg
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 7.21E-5
Slitrk1
Slitrk1tm1.1(KOMP)Vlcg
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp UC Davis | IMPC 7.8E-5
Ap4e1
Ap4e1em1(IMPC)J
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 8.6E-5
Fndc4
Fndc4tm1.1(KOMP)Vlcg
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 8.6E-5
Nrcam
Nrcamtm2e.1(KOMP)Wtsi
HET Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 8.6E-5
Rnf10
Rnf10em1(IMPC)J
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 8.6E-5
Syce1
Syce1tm1b(KOMP)Wtsi
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 8.6E-5
Tex29
Tex29tm1.1(KOMP)Vlcg
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 8.6E-5
Ubn1
Ubn1em1(IMPC)J
HOM Female postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp JAX | IMPC 8.6E-5
Cyp4f16
Cyp4f16tm1b(KOMP)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 9.45E-5
Fbxl21
Fbxl21tm2b(EUCOMM)Wtsi
HOM Male postnatal limb grasping Combined SHIRPA and Dysmorphology | Limb grasp MRC Harwell | IMPC 9.45E-5

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