IMPC Gene variants with increased exploration in new environment
Total number of significant genotype-phenotype associations: 109
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Slitrk2 Slitrk2em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
0.00 | |
Sipa1l1 Sipa1l1tm1.1(KOMP)Vlcg |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
1.17×10-31 | |
Cnih2 Cnih2tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
4.56×10-24 | |
Cacna1g Cacna1gem1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
5.92×10-17 | |
Neurod2 Neurod2em1(IMPC)Hmgu |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
HMGU IMPC |
8.58×10-14 | |
Lrit3 Lrit3em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
9.25×10-12 | |
Kcnc1 Kcnc1em4(IMPC)H |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
5.28×10-11 | |
Slitrk2 Slitrk2em1(IMPC)Mbp |
HEM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
1.85×10-10 | |
Lrrtm1 Lrrtm1em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
4.71×10-10 | |
Abhd13 Abhd13em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
1.56×10-09 | |
Shisa7 Shisa7em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
3.15×10-09 | |
Rhd Rhdtm1e(EUCOMM)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Modified SHIRPA |
WTSI EuroPhenome |
5.94×10-09 | |
Calhm4 Calhm4em1(IMPC)Tcp |
HOM | Early adult | increased exploration in new environment | Latency to center entry Open Field |
TCP IMPC |
7.25×10-09 | |
Hdgfl3 Hdgfl3em1(IMPC)Tcp |
HOM | Late adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
TCP IMPC |
7.64×10-09 | |
Focad Focadem1(IMPC)Bay |
HET | Late adult | increased exploration in new environment | Latency to center entry Open Field |
BCM IMPC |
1.32×10-08 | |
Stx16 Stx16tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
1.48×10-08 | |
Kcnb1 Kcnb1tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
2.32×10-08 | |
Stxbp1 Stxbp1tm1b(EUCOMM)Hmgu |
HET | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
2.58×10-08 | |
Ephb1 Ephb1em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
7.24×10-08 | |
Atp9a Atp9atm1b(EUCOMM)Hmgu |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
HMGU IMPC |
7.25×10-08 | |
AU040320 AU040320em1(IMPC)J |
HOM | Late adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
7.59×10-08 | |
Tmem240 Tmem240em1(IMPC)Ccpcz |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
CCP-IMG IMPC |
1.21×10-07 | |
Slc5a5 Slc5a5tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.45×10-07 | |
Kcnq3 Kcnq3em1(IMPC)H |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.97×10-07 | |
Cnksr2 Cnksr2em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
1.98×10-07 | |
Epb41l1 Epb41l1tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.08×10-07 | |
Ppat Ppatem1(IMPC)Tcp |
HET | Early adult | increased exploration in new environment | Latency to center entry Open Field |
TCP IMPC |
2.23×10-07 | |
Rhoq Rhoqem1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
2.60×10-07 | |
Frmd3 Frmd3em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
3.01×10-07 | |
Slc6a7 Slc6a7em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
3.64×10-07 | |
Tmem14a Tmem14atm2b(KOMP)Wtsi |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.09×10-07 | |
Rab11fip4 Rab11fip4em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
4.79×10-07 | |
Ttyh3 Ttyh3em1(IMPC)Tcp |
HOM | Early adult | increased exploration in new environment | Latency to center entry Open Field |
TCP IMPC |
5.05×10-07 | |
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
HEM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
ICS IMPC |
5.15×10-07 | |
Tspan7 Tspan7em1(IMPC)J |
HEM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
8.25×10-07 | |
Vgf Vgfem1(IMPC)H |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.20×10-06 | |
Dytn Dytnem1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
1.33×10-06 | |
Actr5 Actr5tm2b(EUCOMM)Wtsi |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
BCM IMPC |
1.61×10-06 | |
Satb1 Satb1tm1b(EUCOMM)Hmgu |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.34×10-06 | |
Vldlr Vldlrem1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
2.77×10-06 | |
Trim66 Trim66tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Modified SHIRPA |
WTSI MGP |
2.90×10-06 | |
Arih1 Arih1em1(IMPC)Tcp |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
TCP IMPC |
2.93×10-06 | |
Gtpbp2 Gtpbp2tm1b(KOMP)Mbp |
HOM | Early adult | increased exploration in new environment | Latency to center entry Open Field |
TCP IMPC |
4.42×10-06 | |
Ddx24 Ddx24em1(IMPC)Mbp |
HET | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
5.38×10-06 | |
Csnk1g1 Csnk1g1em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
5.92×10-06 | |
Ykt6 Ykt6em1(IMPC)J |
HET | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
6.21×10-06 | |
Zhx3 Zhx3tm1.1(KOMP)Vlcg |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
6.29×10-06 | |
Dbn1 Dbn1tm1b(KOMP)Wtsi |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
RBRC IMPC |
6.86×10-06 | |
Hnrnpc Hnrnpctm1b(EUCOMM)Hmgu |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
6.99×10-06 | |
Il21r Il21rem1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
7.23×10-06 | |
Cyp4b1 Cyp4b1tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
HMGU IMPC |
7.80×10-06 | |
Mylip Myliptm1.1(KOMP)Vlcg |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
9.02×10-06 | |
Zfp503 Zfp503em1(IMPC)Mbp |
HET | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
1.08×10-05 | |
Tanc2 Tanc2em1(IMPC)Hmgu |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
HMGU IMPC |
1.15×10-05 | |
Abca2 Abca2em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
1.20×10-05 | |
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
HMGU IMPC |
1.24×10-05 | |
Cox4i1 Cox4i1tm1.1(KOMP)Vlcg |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
TCP IMPC |
1.49×10-05 | |
Srbd1 Srbd1em1(IMPC)J |
HET | Late adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
1.51×10-05 | |
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
ICS IMPC |
1.61×10-05 | |
Ankle2 Ankle2em1(IMPC)Bay |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
BCM IMPC |
1.66×10-05 | |
Slc1a1 Slc1a1tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
1.68×10-05 | |
Ephb2 Ephb2em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
1.97×10-05 | |
Eif2a Eif2aem1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
1.97×10-05 | |
Cdkal1 Cdkal1tm2b(EUCOMM)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
HMGU IMPC |
1.98×10-05 | |
Ppp1r9b Ppp1r9btm1.1(KOMP)Vlcg |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
2.06×10-05 | |
Insl5 Insl5Insl5 |
HOM | Early adult | increased exploration in new environment | Latency familiar object exploration Holeboard (GMC) |
HMGU EuroPhenome |
2.48×10-05 | |
Tbc1d30 Tbc1d30em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
2.57×10-05 | |
Tmem67 Tmem67em1(IMPC)J |
HET | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
2.74×10-05 | |
Igsf9b Igsf9bem1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
3.21×10-05 | |
Clec16a Clec16aem1(IMPC)J |
HET | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
3.87×10-05 | |
Snx14 Snx14em1(IMPC)H |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.07×10-05 | |
Ipo7 Ipo7em1(IMPC)Mbp |
HET | Middle aged adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
4.38×10-05 | |
Klhl1 Klhl1em1(IMPC)Ccpcz |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
CCP-IMG IMPC |
4.50×10-05 | |
Adora1 Adora1tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
4.94×10-05 | |
Ppfia3 Ppfia3em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
5.00×10-05 | |
Neurod2 Neurod2em1(IMPC)Hmgu |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
HMGU IMPC |
5.01×10-05 | |
Depdc1a Depdc1aem1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
5.14×10-05 | |
Tmod2 Tmod2tm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
5.18×10-05 | |
Ppp4r2 Ppp4r2tm2b(EUCOMM)Hmgu |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
RBRC IMPC |
5.64×10-05 | |
Plxna4 Plxna4em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
5.82×10-05 | |
Cntnap2 Cntnap2em1(IMPC)H |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
6.06×10-05 | |
Gapvd1 Gapvd1em1(IMPC)Mbp |
HET | Middle aged adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
6.44×10-05 | |
Atp1a3 Atp1a3tm1b(EUCOMM)Hmgu |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
6.62×10-05 | |
Kcnj6 Kcnj6em1(IMPC)H |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
6.63×10-05 | |
Cacna1b Cacna1btm1b(KOMP)Wtsi |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
6.94×10-05 | |
Serpina3i Serpina3iem1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
7.78×10-05 | |
Adcy1 Adcy1tm1b(EUCOMM)Wtsi |
HOM | Late adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
7.95×10-05 | |
Foxe3 Foxe3em1(IMPC)Mbp |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
8.16×10-05 | |
Tppp Tppptm1.1(KOMP)Vlcg |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
8.26×10-05 | |
Itsn2 Itsn2tm1.1(KOMP)Vlcg |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
8.32×10-05 | |
Gpr153 Gpr153em1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
JAX IMPC |
8.35×10-05 | |
Lcorl Lcorlem1(IMPC)J |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
JAX IMPC |
8.83×10-05 | |
Slc25a1 Slc25a1tm1b(EUCOMM)Wtsi |
HET | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
BCM IMPC |
8.94×10-05 | |
Exoc1 Exoc1em1(IMPC)Mbp |
HET | Early adult | increased exploration in new environment | Total holepokes Hole-board Exploration |
UC Davis IMPC |
8.99×10-05 | |
Hdgfl3 Hdgfl3em1(IMPC)Tcp |
HOM | Middle aged adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
TCP IMPC |
9.32×10-05 | |
Krt32 Krt32em1(IMPC)Kmpc |
HOM | Early adult | increased exploration in new environment | Locomotor activity Combined SHIRPA and Dysmorphology |
KMPC IMPC |
9.45×10-05 |