Phenotype: abnormal gait

Definition abnormal pattern of movement of the limbs of animals, characterized by elements of progression, stability, speed and length over the ground

Synonyms
  • abnormal ambulation
  • abnormal ambulation
  • peculiar gait
  • peculiar gait
Related
Synonyms
  • Tip-toe gait
  • Tip-toe gait
  • Short stepped shuffling gait
  • Short stepped shuffling gait
  • short stride length
  • Gait ataxia
  • Broad-based gait
  • Unsteady gait
  • Waddling gait
  • Toe walking
  • Inability to walk by childhood/adolescence
  • Gait imbalance
  • Shuffling gait
  • Progressive gait ataxia
  • Cerebellar ataxia associated with quadrupedal gait
  • Falls
  • Difficulty walking
  • Impaired tandem gait
  • Steppage gait
  • long stride length
  • Abasia
  • Loss of ability to walk
  • abnormal stride length
  • Gait apraxia
  • Gait instability, worse in the dark
  • Scissor gait
  • Loss of ability to walk in first decade
  • Inability to walk
  • Progressive inability to walk
Show more

MP browserMP:0001406

Phenotype associations stats

2.05% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal gait (93/4536)

1.16% females (52/4493) 1.47% males (66/4490)

Gene variants with abnormal gait

Total number of significant genotype-phenotype associations: 122

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Hprt
Hprttm1a(EUCOMM)Hmgu
HEM Female Male postnatal abnormal gait Modified SHIRPA | Gait HMGU | EuroPhenome 0.0
Ndrg1
Ndrg1tm2b(KOMP)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait UC Davis | IMPC 2.03E-18
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 5.19E-18
Gbx1
Gbx1tm1b(KOMP)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.31E-18
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.31E-18
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Female Male postnatal abnormal gait Modified SHIRPA | Gait HMGU | EuroPhenome 4.02E-17
Mpz
Mpzem1(IMPC)Tcp
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait TCP | IMPC 1.48E-16
Arl6ip1
Arl6ip1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 3.76E-16
Frrs1l
Frrs1ltm1b(EUCOMM)Hmgu
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.02E-15
Hmox2
Hmox2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 3.34E-15
Arvcf
Arvcftm1e(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Modified SHIRPA | Gait HMGU | EuroPhenome 7.56E-15
Ngfr
Ngfrtm1b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 8.13E-15
Cdh23
Cdh23tm2b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait (inc. ataxia) WTSI | IMPC 4.16E-14
Gosr2
Gosr2tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 2.22E-13
Lyn
Lyntm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 2.22E-13
Atn1
Atn1tm1b(EUCOMM)Wtsi
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 3.27E-12
Emc10
Emc10tm1b(EUCOMM)Wtsi
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 3.27E-12
Gsk3a
Gsk3atm1b(EUCOMM)Hmgu
HET Female postnatal abnormal gait Modified SHIRPA | Gait HMGU | EuroPhenome 3.5E-12
Marco
Marcotm2b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 1.16E-11
Hexb
Hexbtm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 5.94E-11
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal abnormal gait Modified SHIRPA | Gait MRC Harwell | EuroPhenome 2.85E-10
Cacna1b
Cacna1btm1b(KOMP)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 7.96E-10
Ndrg4
Ndrg4tm1b(KOMP)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 7.96E-10
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.78E-9
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 3.56E-9
Plcb4
Plcb4tm1b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait UC Davis | IMPC 3.95E-9
Pbrm1
Pbrm1tm1b(EUCOMM)Wtsi
HET Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 4.64E-9
Cd300a
Cd300atm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.41E-9
Lefty1
Lefty1tm1b(KOMP)Wtsi
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.41E-9
Pcdh10
Pcdh10tm1bNarl
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.41E-9
Fcgr3
Fcgr3tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.77E-8
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.45E-8
Pparg
Ppargtm1b(KOMP)Wtsi
HET Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.45E-8
Frmd6
Frmd6em1(IMPC)H
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 7.11E-8
Cast
Casttm1.1(KOMP)Vlcg
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait JAX | IMPC 1.12E-7
Dapk1
Dapk1tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.28E-7
Gpr33
Gpr33tm1b(EUCOMM)Hmgu
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.28E-7
Ppfia2
Ppfia2tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.28E-7
Prdm4
Prdm4tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.28E-7
Sema3f
Sema3ftm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 2.29E-7
Mir96
Mir96tm2.2(IMPC)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait (inc. ataxia) WTSI | IMPC 2.32E-7
Trpc3
Trpc3Mwk
HET Female Male postnatal abnormal gait Modified SHIRPA | Gait MRC Harwell | EuroPhenome 2.71E-7
Aspa
Aspatm1b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 2.91E-7
Uhrf1
Uhrf1tm1a(EUCOMM)Wtsi
HET Male postnatal abnormal gait Modified SHIRPA | Gait HMGU | EuroPhenome 5.52E-7
Hells
Hellstm1a(EUCOMM)Wtsi
HOM Female postnatal abnormal gait Modified SHIRPA | Gait HMGU | EuroPhenome 5.93E-7
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.67E-7
Sorl1
Sorl1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.67E-7
Ube2b
Ube2btm1b(EUCOMM)Wtsi
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.67E-7
Usmg5
Usmg5tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.67E-7
Usp22
Usp22tm1b(KOMP)Wtsi
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 9.67E-7
Smoc1
Smoc1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.03E-6
Krt90
Krt90em1(IMPC)J
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait JAX | IMPC 1.12E-6
Scn4b
Scn4bem1(IMPC)Wtsi
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait (inc. ataxia) WTSI | IMPC 1.56E-6
Zfp287
Zfp287tm1b(EUCOMM)Wtsi
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait (inc. ataxia) WTSI | IMPC 1.56E-6
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait RBRC | IMPC 1.66E-6
Armh4
Armh4em1(IMPC)H
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.72E-6
Rgl3
Rgl3em1(IMPC)H
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.72E-6
Sirt3
Sirt3tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.72E-6
Sirt4
Sirt4tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.72E-6
Zfp106
Zfp106tm1a(KOMP)Wtsi
HOM Male postnatal abnormal gait Modified SHIRPA | Gait WTSI | EuroPhenome 1.98E-6
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 2.82E-6
Psmc2
Psmc2tm1b(EUCOMM)Hmgu
HET Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 5.08E-6
Plcz1
Plcz1em1(IMPC)H
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 8.83E-6
Impad1
Impad1tm1a(KOMP)Wtsi
HET Male postnatal abnormal gait Modified SHIRPA | Gait WTSI | EuroPhenome 9.21E-6
Map2k2
Map2k2tm1a(EUCOMM)Wtsi
HOM Female postnatal abnormal gait Modified SHIRPA | Gait WTSI | MGP 1.1E-5
Mir96
Mir96Dmdo
HOM Male postnatal abnormal gait Modified SHIRPA | Gait WTSI | EuroPhenome 1.18E-5
Stat1
Stat1tm2b(EUCOMM)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait ICS | IMPC 1.34E-5
Babam2
Babam2tm1a(EUCOMM)Wtsi
HOM Male postnatal abnormal gait Modified SHIRPA | Gait MRC Harwell | EuroPhenome 1.39E-5
Kcnb1
Kcnb1tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.4E-5
Morc2a
Morc2atm1b(KOMP)Wtsi
HET Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.4E-5
Sez6l
Sez6ltm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.4E-5
Snapc1
Snapc1tm1b(KOMP)Mbp
HET Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.4E-5
Svop
Svopem1(IMPC)H
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.4E-5
Pde1a
Pde1aem1(IMPC)H
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 1.76E-5
Cldn16
Cldn16tm1a(KOMP)Wtsi
HOM Male postnatal abnormal gait Modified SHIRPA | Gait WTSI | MGP 1.94E-5
Mfn2
Mfn2tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 2.11E-5
Arl4a
Arl4atm1Asch
HOM Female postnatal abnormal gait Shirpa (GMC) | Gait HMGU | EuroPhenome 2.46E-5
Gde1
Gde1tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 2.49E-5
Gbx1
Gbx1
HOM Female postnatal abnormal gait Modified SHIRPA | Gait ICS | EuroPhenome 3.65E-5
Hmx3
Hmx3tm1Ebo
HOM Male postnatal abnormal gait Modified SHIRPA | Gait WTSI | EuroPhenome 4.11E-5
Rccd1
Rccd1tm1.1(KOMP)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 4.18E-5
Stk3
Stk3em1(IMPC)H
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 4.18E-5
Hoxa2
Hoxa2tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 5.67E-5
Ldlr
Ldlrtm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 6.23E-5
Barx2
Barx2tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.63E-5
Clstn3
Clstn3tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.63E-5
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.63E-5
Gpr22
Gpr22tm1b(KOMP)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.63E-5
Slc4a10
Slc4a10tm1b(KOMP)Wtsi
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.63E-5
Trim39
Trim39tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait MRC Harwell | IMPC 6.63E-5
P2rx5
P2rx5tm1b(EUCOMM)Hmgu
HET Female Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 6.94E-5
Ppy
Ppytm1b(KOMP)Wtsi
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait HMGU | IMPC 6.94E-5
Nab2
Nab2tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait ICS | IMPC 6.95E-5
Setdb2
Setdb2tm1a(KOMP)Wtsi
HOM Male postnatal abnormal gait Modified SHIRPA | Gait HMGU | EuroPhenome 8.14E-5
Odf3l2
Odf3l2tm1.1(KOMP)Vlcg
HET Male postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait UC Davis | IMPC 8.8E-5
Baiap2l2
Baiap2l2tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal gait Combined SHIRPA and Dysmorphology | Gait ICS | IMPC 9.81E-5

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