Phenotype: persistence of hyaloid vascular system

Definition failure of the degeneration of the transient vascular system of the eye during development, that normally nourishes the retina, immature lens and primary vitreous of the developing eye

Synonyms persistence of hyaloid capillary system

MP browserMP:0001289

Phenotype associations stats

1.23% of tested genes with null mutations on a B6N genetic background have a phenotype association to persistence of hyaloid vascular system (43/3489)

0.61% females (21/3421) 0.88% males (30/3405)

Gene variants with persistence of hyaloid vascular system

Total number of significant genotype-phenotype associations: 51

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Arhgap44
Arhgap44em1(IMPC)J
HOM Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 0.0
Zbtb43
Zbtb43tm1b(KOMP)Mbp
HET Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 0.0
Myo10
Myo10tm2(KOMP)Wtsi
HOM Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system WTSI | IMPC 3.92E-15
Agap1
Agap1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system WTSI | IMPC 6.23E-15
Kctd1
Kctd1em1(IMPC)J
HOM Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 2.16E-11
Clstn1
Clstn1tm1b(EUCOMM)Hmgu
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 7.72E-11
Pdhx
Pdhxtm1b(EUCOMM)Hmgu
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system HMGU | IMPC 1.11E-10
Mapt
Mapttm1b(EUCOMM)Hmgu
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system ICS | IMPC 1.35E-10
R3hcc1l
R3hcc1ltm1b(KOMP)Wtsi
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 3.2E-9
Frmd6
Frmd6em1(IMPC)H
HOM Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 7.18E-9
Pcsk1
Pcsk1tm1b(EUCOMM)Wtsi
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system ICS | IMPC 4.16E-8
Dnm1l
Dnm1ltm1b(KOMP)Wtsi
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system ICS | IMPC 6.1E-8
Sox30
Sox30tm1b(KOMP)Wtsi
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system BCM | IMPC 3.29E-7
Aptx
Aptxtm1b(EUCOMM)Hmgu
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 4.96E-7
Ncoa3
Ncoa3tm1b(EUCOMM)Wtsi
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 1.07E-6
Nt5dc1
Nt5dc1em1(IMPC)J
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 1.17E-6
Cbx2
Cbx2tm1b(KOMP)Wtsi
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 1.24E-6
Synj1
Synj1tm1b(EUCOMM)Wtsi
HET Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 1.38E-6
Tbc1d5
Tbc1d5em1(IMPC)J
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 1.53E-6
Coq6
Coq6tm1b(EUCOMM)Hmgu
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system ICS | IMPC 1.78E-6
Ylpm1
Ylpm1tm1b(KOMP)Wtsi
HET Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 2.61E-6
Cdsn
Cdsntm1b(EUCOMM)Hmgu
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system HMGU | IMPC 3.86E-6
Rusc1
Rusc1em1(IMPC)J
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 4.56E-6
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system HMGU | IMPC 5.28E-6
Zbtb4
Zbtb4tm1.1(KOMP)Vlcg
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 5.58E-6
Rab11a
Rab11atm1b(KOMP)Wtsi
HET Female Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 5.87E-6
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system WTSI | IMPC 7.6E-6
Ptpru
Ptprutm1.1(KOMP)Vlcg
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 8.67E-6
Pip5k1c
Pip5k1ctm1b(KOMP)Wtsi
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 1.01E-5
Nadk2
Nadk2em1(IMPC)J
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 1.77E-5
Cldn13
Cldn13em1(IMPC)J
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 1.96E-5
Cyba
Cybatm1a(EUCOMM)Wtsi
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system WTSI | IMPC 2.4E-5
Myo7a
Myo7atm1a(EUCOMM)Wtsi
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system WTSI | IMPC 2.4E-5
Casz1
Casz1tm1b(EUCOMM)Hmgu
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 3.26E-5
Gfpt1
Gfpt1tm1b(EUCOMM)Wtsi
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 3.26E-5
Usp38
Usp38tm1b(EUCOMM)Hmgu
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 3.26E-5
Cstf3
Cstf3tm2b(EUCOMM)Hmgu
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system HMGU | IMPC 3.32E-5
Nr6a1
Nr6a1tm1b(EUCOMM)Wtsi
HET Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system BCM | IMPC 3.67E-5
Klf7
Klf7tm1b(EUCOMM)Hmgu
HET Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system MRC Harwell | IMPC 4.01E-5
Akr1d1
Akr1d1tm1.1(KOMP)Vlcg
HOM Male postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 4.72E-5
Rbl2
Rbl2tm1b(EUCOMM)Hmgu
HET Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system JAX | IMPC 4.77E-5
Lama1
Lama1tm2b(EUCOMM)Hmgu
HET Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system HMGU | IMPC 7.16E-5
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Female postnatal persistence of hyaloid vascular system Eye Morphology | Persistence of hyaloid vascular system HMGU | IMPC 9.01E-5

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Images

  • Cdkn2atm1a(EUCOMM)Wtsi
    eye, persistence of hyaloid vascular system, HOM, Male, WTSI
  • Cdkn2atm1a(EUCOMM)Wtsi
    eye, persistence of hyaloid vascular system, HOM, Male, WTSI
  • Cdkn2atm1a(EUCOMM)Wtsi
    eye, persistence of hyaloid vascular system, abnormal retinal pigmentation, HOM, Male, WTSI
  • Cdkn2atm1a(EUCOMM)Wtsi
    eye, persistence of hyaloid vascular system, HOM, Female, WTSI
  • Cdkn2atm1a(EUCOMM)Wtsi
    eye, persistence of hyaloid vascular system, abnormal retinal pigmentation, HOM, Female, WTSI

Associated Images

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