MP:0001192 (scaly skin) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: scaly skin

Definition

loss of the outer layer of the epidermis in thick, dry scale-like patches

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 8

Gene / Allele	Zygosity	Life Stage	Phenotype	Parameter	Phenotyping Center
Atf6b Atf6b^{tm1.1(KOMP)Vlcg}	HET	Early adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC
Krtap17-1 Krtap17-1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC
Lypd6 Lypd6^{tm1b(KOMP)Wtsi}	HET	Early adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC
Mid2 Mid2^{tm1b(KOMP)Wtsi}	HEM	Early adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC
Smg6 Smg6^em1(IMPC)Mbp	HET	Early adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC
Terf2ip Terf2ip^em1(IMPC)Mbp	HOM	Early adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC
Tiparp Tiparp^{tm1b(EUCOMM)Wtsi}	HET	Early adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC
Vrk3 Vrk3^em1(IMPC)Mbp	HOM	Late adult	scaly skin	Skin Gross Pathology and Tissue Collection	UC Davis IMPC

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Procedure
Combined SHIRPA and Dysmorphology
Dysmorphology

0.72% of tested genes with null mutations on a B6N genetic background have a phenotype association to scaly skin (8/1109)

0.36% females (4/1108) 0.36% males (4/1105)

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