Phenotype: enlarged liver

Definition
larger than average size of the liver
Synonyms
increased liver size,  hepatomegaly
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with enlarged liver

Total number of significant genotype-phenotype associations: 38

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
1700034E13Rik
1700034E13Rikem1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Abcg8
Abcg8tm1b(KOMP)Wtsi
HOM Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
CCP-IMG
IMPC
0.00
Acoxl
Acoxlem1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Afdn
Afdnem1(IMPC)Mbp
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Cd36
Cd36em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Chst2
Chst2em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Clasp1
Clasp1em1(IMPC)Mbp
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Cyp4v3
Cyp4v3em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Epha6
Epha6tm1b(KOMP)Wtsi
HOM Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Extl3
Extl3em1(IMPC)Mbp
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Gapvd1
Gapvd1em1(IMPC)Mbp
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Gna15
Gna15em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Hacd3
Hacd3em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Irag1
Irag1em1(IMPC)Ccpcz
HOM Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
CCP-IMG
IMPC
0.00
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
MRC Harwell
IMPC
0.00
Luc7l
Luc7lem1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Padi4
Padi4em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Pstpip1
Pstpip1em1(IMPC)Ccpcz
HOM Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
CCP-IMG
IMPC
0.00
Slc29a3
Slc29a3em1(IMPC)Mbp
HOM Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Slc9b1
Slc9b1em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Tbl1xr1
Tbl1xr1tm1b(EUCOMM)Hmgu
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
HMGU
IMPC
0.00
Tle4
Tle4em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Tmed6
Tmed6em1(IMPC)Rbrc
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
RBRC
IMPC
0.00
Tnfaip8l1
Tnfaip8l1em1(IMPC)Mbp
HOM Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Trp53inp2
Trp53inp2em1(IMPC)Mbp
HOM Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Ubtf
Ubtfem1(IMPC)Mbp
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Wars1
Wars1tm1b(EUCOMM)Hmgu
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
HMGU
IMPC
0.00
Wdfy3
Wdfy3em1(IMPC)Mbp
HET Late adult enlarged liver Liver
Gross Pathology and Tissue Collection
UC Davis
IMPC
0.00
Zc3h8
Zc3h8em1(IMPC)Ccpcz
HET Early adult enlarged liver Liver
Gross Pathology and Tissue Collection
CCP-IMG
IMPC
0.00
Slc29a3
Slc29a3em1(IMPC)Mbp
HOM Early adult increased liver weight Liver weight
Organ Weight
UC Davis
IMPC
3.12×10-08
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM Early adult increased liver weight Liver weight
Organ Weight
UC Davis
IMPC
2.68×10-07
Babam1
Babam1em1(IMPC)Ccpcz
HOM   Early adult increased liver weight Whole liver weight
Organ Weight
CCP-IMG
IMPC
1.37×10-05
Rhpn1
Rhpn1tm1b(KOMP)Wtsi
HOM Early adult increased liver weight Liver weight
Organ Weight
UC Davis
IMPC
1.68×10-05
Rabl2
Rabl2tm1.1(KOMP)Wtsi
HOM Early adult increased liver weight Liver weight
Organ Weight
UC Davis
IMPC
4.64×10-05
Wdr49
Wdr49em1(IMPC)Ccpcz
HOM Early adult increased liver weight Whole liver weight
Organ Weight
CCP-IMG
IMPC
8.41×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Organ Weight

 Phenotype associations stats

3.58% of tested genes with null mutations on a B6N genetic background have a phenotype association to enlarged liver (35/978)

0.82% females (3/367) 3.37% males (33/980)

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