Definition
any structural anomaly of the lower bony framework of the mouth where the inferior teeth are held
Synonyms
abnormal lower jaw morphology,
mandible dysplasia
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal mandible morphology
Total number of significant genotype-phenotype associations: 8
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Lrrk1 Lrrk1tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal mandible morphology | Mandibles X-ray |
MRC Harwell IMPC |
2.75×10-14 | |
| Tent5a Tent5aem1(IMPC)Ccpcz |
HOM | Early adult | abnormal mandible morphology | Mandibles X-ray |
CCP-IMG IMPC |
3.84×10-11 | |
| Fbn2 Fbn2em1(IMPC)Rbrc |
HOM | Early adult | abnormal mandible morphology | Mandibles X-ray |
RBRC IMPC |
6.97×10-11 | |
| Spred1 Spred1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal mandible morphology | Mandibles X-ray |
CCP-IMG IMPC |
2.46×10-08 | |
| Slc25a21 Slc25a21tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal mandible morphology | Mandibles X-ray |
WTSI MGP |
2.73×10-08 | |
| Gkn1 Gkn1tm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal mandible morphology | Mandibles X-ray |
UC Davis IMPC |
2.34×10-07 |