Phenotype: abnormal mandible morphology

Definition
any structural anomaly of the lower bony framework of the mouth where the inferior teeth are held
Synonyms
abnormal lower jaw morphology,  mandible dysplasia
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal mandible morphology

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Early adult abnormal mandible morphology Mandibles
X-ray
MRC Harwell
IMPC
2.75×10-14
Tent5a
Tent5aem1(IMPC)Ccpcz
HOM Early adult abnormal mandible morphology Mandibles
X-ray
CCP-IMG
IMPC
3.84×10-11
Fbn2
Fbn2em1(IMPC)Rbrc
HOM Early adult abnormal mandible morphology Mandibles
X-ray
RBRC
IMPC
6.97×10-11
Spred1
Spred1em1(IMPC)Ccpcz
HOM Early adult abnormal mandible morphology Mandibles
X-ray
CCP-IMG
IMPC
2.46×10-08
Slc25a21
Slc25a21tm1a(KOMP)Wtsi
HOM Early adult abnormal mandible morphology Mandibles
X-ray
WTSI
MGP
2.73×10-08
Gkn1
Gkn1tm1.1(KOMP)Vlcg
HOM Early adult abnormal mandible morphology Mandibles
X-ray
UC Davis
IMPC
2.34×10-07

Download data as:   TSV   XLS

 The way we measure

Procedure
X-ray
X-Ray
X-Ray (GMC)

 Phenotype associations stats

0.34% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal mandible morphology (6/1771)

0.17% females (3/1761) 0.28% males (5/1769)

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter