Phenotype: increased monocyte cell number

Definition greater count of the large, phagocytic mononuclear leukocytes produced in the vertebrate bone marrow and released into the blood

Synonyms
  • increased monocyte count
  • increased monocyte count
  • monocytosis
  • monocytosis
  • increased monocyte number
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Related
Synonyms
  • increased Ly6C high monocyte number
  • increased Ly6C high monocyte number
  • increased Ly6C low monocyte number
  • increased Ly6C low monocyte number

MP browserMP:0000220

Phenotype associations stats

1.62% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased monocyte cell number (55/3397)

0.92% females (30/3256) 1.12% males (37/3306)

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Gene variants with increased monocyte cell number

Total number of significant genotype-phenotype associations: 103

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Mesenteric Lymph Node Immunophenotyping | Monocytes - % of CD45+ WTSI | 3i 0.0
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 0.0
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte number WTSI | 3i 0.0
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 0.0
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 0.0
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Mesenteric Lymph Node Immunophenotyping | Monocytes - % of CD45+ WTSI | 3i 0.0
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 0.0
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Mesenteric Lymph Node Immunophenotyping | Monocytes - % of CD45+ WTSI | 3i 0.0
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte number WTSI | 3i 0.0
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 0.0
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 0.0
Dph6
Dph6tm1a(KOMP)Wtsi
HOM Female Male postnatal increased monocyte cell number Spleen Immunophenotyping | Monocytes - % of CD45+ WTSI | 3i 0.0
Dph6
Dph6tm1a(KOMP)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 0.0
Gmds
Gmdstm1a(KOMP)Wtsi
HOM Female Male postnatal increased monocyte cell number Spleen Immunophenotyping | Monocytes - % of CD45+ WTSI | 3i 0.0
Herc1
Herc1em3(IMPC)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 0.0
Herc1
Herc1em3(IMPC)Wtsi
HOM Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte number WTSI | 3i 0.0
Irgm1
Irgm1em1(IMPC)Wtsi
HOM Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 0.0
Ncf2
Ncf2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 0.0
Setd5
Setd5tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 0.0
Tmem127
Tmem127tm1(KOMP)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte percentage WTSI | 3i 0.0
Wac
Wactm2b(EUCOMM)Wtsi
HET Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 0.0
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count MRC Harwell | IMPC 1.26E-18
Atp5md
Atp5mdtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte cell count MRC Harwell | IMPC 5.22E-15
Cstb
Cstbtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count ICS | IMPC 7.7E-11
Hdac8
Hdac8tm1a(EUCOMM)Wtsi
HEM Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 3.05E-10
Lyn
Lyntm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count MRC Harwell | IMPC 1.98E-9
Rft1
Rft1tm1b(KOMP)Wtsi
HET Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count MRC Harwell | IMPC 5.85E-9
Spns2
Spns2tm1b(KOMP)Wtsi
HOM Female Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 1.64E-8
Spns2
Spns2tm1a(KOMP)Wtsi
HOM Female postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 9.77E-8
Rnf216
Rnf216tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count TCP | IMPC 5.74E-7
Arhgap30
Arhgap30tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte percentage WTSI | 3i 6.0E-7
Fbxl8
Fbxl8em2(IMPC)Marc
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count MARC | IMPC 8.48E-7
Bap1
Bap1tm1a(EUCOMM)Hmgu
HET Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 9.0E-7
Spink14
Spink14tm1e(KOMP)Wtsi
HOM Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 9.0E-7
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte number WTSI | 3i 1.0E-6
Usp4
Usp4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 1.37E-6
Wac
Wactm2b(EUCOMM)Wtsi
HET Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 2.3E-6
Ctsm
Ctsmtm1(KOMP)Wtsi
HOM Male postnatal increased monocyte cell number Hematology | Monocyte differential count MARC | IMPC 2.8E-6
Hexb
Hexbtm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count MRC Harwell | IMPC 2.95E-6
Dph2
Dph2tm2(EUCOMM)Wtsi
HET Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 5.14E-6
Herc1
Herc1em3(IMPC)Wtsi
HOM Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte number WTSI | 3i 5.4E-6
Dll1
Dll1tm1Gos
HET Female postnatal increased monocyte cell number Haematology (GMC) | Absolute number of monocytes HMGU | EuroPhenome 6.11E-6
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Female Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 7.12E-6
Bmp7
Bmp7tm1a(EUCOMM)Hmgu
HET Male postnatal increased monocyte cell number FACs Analysis | Monocyte gate MRC Harwell | EuroPhenome 7.71E-6
Gatad2b
Gatad2btm1b(EUCOMM)Hmgu
HET Male postnatal increased monocyte cell number Hematology | Monocyte differential count ICS | IMPC 8.2E-6
Prkaa2
Prkaa2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count MRC Harwell | IMPC 1.03E-5
Brpf1
Brpf1tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased monocyte cell number FACs Analysis | Monocyte gate MRC Harwell | EuroPhenome 1.17E-5
Stk32a
Stk32atm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 1.26E-5
Cd19
Cd19em2(IMPC)Ics
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count ICS | IMPC 1.75E-5
Epx
Epxtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count ICS | IMPC 2.08E-5
Mpig6b
Mpig6btm1.1(KOMP)Vlcg
HOM Male postnatal increased monocyte cell number Hematology | Monocyte differential count UC Davis | IMPC 2.11E-5
Atp11a
Atp11atm1a(KOMP)Wtsi
HET Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte number WTSI | 3i 2.12E-5
Bap1
Bap1tm1a(EUCOMM)Hmgu
HET Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte number WTSI | 3i 2.12E-5
Crls1
Crls1tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased Ly6C low monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Clow monocyte number WTSI | 3i 2.12E-5
Crls1
Crls1tm1a(EUCOMM)Wtsi
HET Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte number WTSI | 3i 2.12E-5
Atp11a
Atp11atm1a(KOMP)Wtsi
HET Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte number WTSI | 3i 2.26E-5
Gimap6
Gimap6tm1a(KOMP)Wtsi
HOM Female Male postnatal increased monocyte cell number Whole blood peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 2.26E-5
Gmds
Gmdstm1a(KOMP)Wtsi
HOM Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte number WTSI | 3i 2.26E-5
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte percentage WTSI | 3i 2.26E-5
Lpin3
Lpin3tm1b(KOMP)Wtsi
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count UC Davis | IMPC 2.27E-5
Fbxl19
Fbxl19tm1b(EUCOMM)Wtsi
HET Male postnatal increased monocyte cell number Hematology | Monocyte differential count MARC | IMPC 2.79E-5
Ikzf3
Ikzf3tm1(KOMP)Vlcg
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count RBRC | IMPC 2.89E-5
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 3.21E-5
Tcaim
Tcaimtm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Hematology | Monocyte differential count MRC Harwell | IMPC 3.6E-5
Rnf169
Rnf169tm1a(EUCOMM)Hmgu
HOM Male postnatal increased monocyte cell number FACs Analysis | Monocyte gate MRC Harwell | EuroPhenome 4.02E-5
Sqstm1
Sqstm1tm1a(KOMP)Wtsi
HOM Female Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 4.94E-5
Stambp
Stambptm1b(EUCOMM)Hmgu
HET Female postnatal increased monocyte cell number Hematology | Monocyte differential count MRC Harwell | IMPC 5.46E-5
Ezh2
Ezh2tm1a(EUCOMM)Wtsi
HET Female postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 5.58E-5
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased Ly6C high monocyte number Whole blood peripheral blood leukocyte immunophenotyping | Ly6Chigh monocyte number WTSI | 3i 5.71E-5
Smarcal1
Smarcal1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 7.49E-5
H2-Eb1
H2-Eb1tm1a(KOMP)Wtsi
HOM Male postnatal increased monocyte cell number Buffy coat peripheral blood leukocyte immunophenotyping | Monocyte percentage WTSI | 3i 7.87E-5
Gabarapl2
Gabarapl2tm1b(EUCOMM)Hmgu
HET Male postnatal increased monocyte cell number Hematology | Monocyte cell count MRC Harwell | IMPC 8.75E-5

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Images

  • Spns2tm1b(KOMP)Wtsi
    increased monocyte cell number, increased granulocyte number, HOM, Female, WTSI
  • Spns2tm1b(KOMP)Wtsi
    increased monocyte cell number, increased granulocyte number, HOM, Female, WTSI