Phenotype: decreased hematocrit

Definition less than the average percentage of a volume of a blood sample occupied by red blood cells

Synonyms reduced hematocrit

MP browserMP:0000208

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Phenotype associations stats

1.52% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased hematocrit (52/3425)

1.18% females (40/3399) 1.41% males (48/3416)

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Gene variants with decreased hematocrit

Total number of significant genotype-phenotype associations: 96

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Haematology | Haematocrit WTSI | EuroPhenome 1.97E-37
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit WTSI | IMPC 1.54E-17
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit TCP | IMPC 9.68E-14
Gna11
Gna11tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit MRC Harwell | IMPC 6.07E-12
Tmem189
Tmem189tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit WTSI | IMPC 4.56E-11
Vrk3
Vrk3em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 4.17E-10
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit WTSI | IMPC 1.05E-9
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit MARC | IMPC 1.81E-9
Fbxo11
Fbxo11tm2b(EUCOMM)Wtsi
HET Female Male postnatal decreased hematocrit Hematology | Hematocrit MRC Harwell | IMPC 5.96E-9
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased hematocrit Haematology | Haematocrit MRC Harwell | EuroPhenome 7.23E-9
Dpy19l1
Dpy19l1em1Mbp
HET Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 8.04E-9
Dpy19l1
Dpy19l1em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 8.04E-9
Slc25a14
Slc25a14em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 1.23E-8
5430419D17Rik
5430419D17Rikem1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 4.19E-8
Dpy19l3
Dpy19l3tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hematocrit Haematology | Haematocrit ICS | EuroPhenome 5.15E-8
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hematocrit Haematology | Haematocrit MRC Harwell | EuroPhenome 1.19E-7
Caskin1
Caskin1em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 1.24E-7
Lrrc8c
Lrrc8cem1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 1.72E-7
Tas2r139
Tas2r139em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 1.91E-7
Plcg2
Plcg2Ali14
HET Male postnatal decreased hematocrit Haematology | Haematocrit HMGU | EuroPhenome 2.41E-7
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit TCP | IMPC 4.89E-7
Cp
Cptm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit JAX | IMPC 6.7E-7
Myl12b
Myl12btm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hematocrit Haematology test | Haematocrit WTSI | MGP 8.34E-7
Mecom
MecomJbo
HET Female Male postnatal decreased hematocrit Haematology | Haematocrit MRC Harwell | EuroPhenome 1.02E-6
Osm
Osmtm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit JAX | IMPC 1.21E-6
Pdik1l
Pdik1lem1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 1.69E-6
Plekhm2
Plekhm2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hematocrit Haematology test | Haematocrit WTSI | MGP 2.88E-6
Stard13
Stard13tm1a(KOMP)Wtsi
HOM Female postnatal decreased hematocrit Haematology test | Haematocrit WTSI | MGP 3.36E-6
Etaa1
Etaa1em1Marc
HOM Male postnatal decreased hematocrit Hematology | Hematocrit MARC | IMPC 4.31E-6
Kcna10
Kcna10em3Mbp
HET Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 4.4E-6
Irf8
Irf8tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit JAX | IMPC 5.13E-6
Spata46
Spata46em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 5.66E-6
Prkab1
Prkab1tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Haematology test | Haematocrit WTSI | MGP 6.12E-6
Sgtb
Sgtbem1Mbp
HOM Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 7.34E-6
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HOM Female postnatal decreased hematocrit Hematology | Hematocrit MRC Harwell | IMPC 1.02E-5
Gsdma3
Gsdma3tm1(KOMP)Vlcg
HOM Male postnatal decreased hematocrit Hematology | Hematocrit MARC | IMPC 1.02E-5
Enox1
Enox1tm1.1(KOMP)Vlcg
HET Female postnatal decreased hematocrit Hematology | Hematocrit JAX | IMPC 1.11E-5
Enox1
Enox1tm1.1(KOMP)Vlcg
HOM Female postnatal decreased hematocrit Hematology | Hematocrit JAX | IMPC 1.11E-5
Dph6
Dph6tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit WTSI | IMPC 1.41E-5
Sec61b
Sec61bem1Mbp
HOM Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 1.44E-5
Miga2
Miga2tm1a(KOMP)Wtsi
HOM Male postnatal decreased hematocrit Haematology test | Haematocrit WTSI | MGP 1.61E-5
Rock1
Rock1tm1b(NCOM)Mfgc
HET Female postnatal decreased hematocrit Hematology | Hematocrit TCP | IMPC 1.68E-5
Rock1
Rock1tm1b(NCOM)Mfgc
HOM Female postnatal decreased hematocrit Hematology | Hematocrit TCP | IMPC 1.68E-5
Pank3
Pank3tm1b(KOMP)Mbp
HOM Male postnatal decreased hematocrit Hematology | Hematocrit MRC Harwell | IMPC 1.82E-5
Syce1l
Syce1ltm1.1(KOMP)Vlcg
HET Female Male postnatal decreased hematocrit Hematology | Hematocrit JAX | IMPC 2.54E-5
Syce1l
Syce1ltm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit JAX | IMPC 2.54E-5
Ces2e
Ces2eem1Marc
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit MARC | IMPC 2.66E-5
Phactr1
Phactr1em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 3.34E-5
Dctn5
Dctn5tm2a(KOMP)Wtsi
HET Male postnatal decreased hematocrit Haematology test | Haematocrit WTSI | MGP 3.43E-5
Uevld
Uevldtm1a(EUCOMM)Wtsi
HOM Male postnatal decreased hematocrit Hematology | Hematocrit WTSI | IMPC 3.46E-5
Olfr392
Olfr392em1Mbp
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 4.34E-5
Ing4
Ing4em2Tcp
HOM Male postnatal decreased hematocrit Hematology | Hematocrit TCP | IMPC 4.83E-5
Rbm11
Rbm11em1Marc
HOM Female Male postnatal decreased hematocrit Hematology | Hematocrit MARC | IMPC 6.07E-5
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased hematocrit Haematology test | Haematocrit WTSI | EuroPhenome 6.66E-5
Edc4
Edc4tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased hematocrit Hematology | Hematocrit WTSI | IMPC 7.02E-5
Arhgef12
Arhgef12tm1b(KOMP)Wtsi
HET Female Male postnatal decreased hematocrit Hematology | Hematocrit UC Davis | IMPC 7.96E-5
Fgf9
Fgf9tm1b(KOMP)Wtsi
HET Male postnatal decreased hematocrit Hematology | Hematocrit MRC Harwell | IMPC 9.69E-5

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