Definition
abnormally high concentration of calcium ions in the circulating blood
Synonyms
increased circulating calcium,
hypercalcemia,
hypercalcaemia
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased circulating calcium level
Total number of significant genotype-phenotype associations: 136
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
0.00 | |
| Itch Itchtm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
4.19×10-32 | |
| Lepr Leprtm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
6.98×10-31 | |
| Gna11 Gna11tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell EuroPhenome |
7.37×10-28 | |
| Slc25a4 Slc25a4tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
6.38×10-25 | |
| Kctd1 Kctd1em1(IMPC)J |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
9.04×10-25 | |
| Col4a5 Col4a5tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
4.88×10-15 | |
| Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
1.58×10-13 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
4.85×10-13 | |
| Syt17 Syt17tm1b(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
1.98×10-12 | |
| Eftud2 Eftud2tm1b(KOMP)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
2.87×10-12 | |
| Dnajc30 Dnajc30tm1.1(KOMP)Vlcg |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
6.14×10-12 | |
| Cldn16 Cldn16tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI MGP |
9.88×10-12 | |
| Col4a5 Col4a5tm1b(EUCOMM)Wtsi |
HEM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
6.95×10-11 | |
| Hectd1 Hectd1tm1b(EUCOMM)Hmgu |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MARC IMPC |
5.15×10-10 | |
| Lrba Lrbaem1(IMPC)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
2.00×10-09 | |
| Abcd3 Abcd3em1(IMPC)J |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
5.57×10-09 | |
| Tmem203 Tmem203em1(IMPC)H |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
2.39×10-08 | |
| Txnip Txniptm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
3.52×10-08 | |
| Zfp106 Zfp106tm1a(KOMP)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI EuroPhenome |
3.98×10-08 | |
| Rnf214 Rnf214em1(IMPC)J |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
5.24×10-08 | |
| Nfya NfyaNfya |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS EuroPhenome |
7.26×10-08 | |
| Tmem237 Tmem237tm1b(EUCOMM)Hmgu |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
CCP-IMG IMPC |
1.03×10-07 | |
| Slc12a1 Slc12a1urehr3 |
HOM | Early adult | increased circulating calcium level | Calcium Clinical chemistry (GMC) |
HMGU EuroPhenome |
1.40×10-07 | |
| Cxcr2 Cxcr2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
1.49×10-07 | |
| Ndufs3 Ndufs3tm1a(EUCOMM)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS EuroPhenome |
2.78×10-07 | |
| Kcnh6 Kcnh6tm1.1(KOMP)Vlcg |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
2.91×10-07 | |
| Fads6 Fads6tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
3.24×10-07 | |
| Rnf144b Rnf144btm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
3.80×10-07 | |
| Zfp445 Zfp445tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
4.94×10-07 | |
| Phykpl Phykpltm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS EuroPhenome |
5.47×10-07 | |
| Fam184b Fam184btm2b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
5.50×10-07 | |
| Stk39 Stk39tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI MGP |
6.14×10-07 | |
| Zdhhc20 Zdhhc20em1(IMPC)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
8.02×10-07 | |
| Kdm4c Kdm4ctm1a(KOMP)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU EuroPhenome |
9.86×10-07 | |
| Gys2 Gys2tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI EuroPhenome |
1.07×10-06 | |
| Cpn1 Cpn1tm1b(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
1.12×10-06 | |
| Fam234b Fam234btm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU EuroPhenome |
1.16×10-06 | |
| Slc16a2 Slc16a2tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI MGP |
1.27×10-06 | |
| Ndfip2 Ndfip2tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
1.38×10-06 | |
| Dnah5 Dnah5tm1b(KOMP)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
2.76×10-06 | |
| Mxd4 Mxd4em1(IMPC)J |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
2.81×10-06 | |
| Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
2.82×10-06 | |
| Foxj3 Foxj3tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
BCM IMPC |
2.90×10-06 | |
| Cpe Cpetm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
3.69×10-06 | |
| Eif2ak2 Eif2ak2em1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
3.78×10-06 | |
| Wdr37 Wdr37tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
3.80×10-06 | |
| Bcar3 Bcar3em1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
3.89×10-06 | |
| Arhgef4 Arhgef4tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU EuroPhenome |
4.15×10-06 | |
| Prrg2 Prrg2tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
4.86×10-06 | |
| Sae1 Sae1em1(IMPC)J |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
4.98×10-06 | |
| Dsg1c Dsg1cem1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
5.66×10-06 | |
| Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
5.84×10-06 | |
| Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
6.15×10-06 | |
| Pdpn Pdpntm1b(EUCOMM)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
6.47×10-06 | |
| Slitrk4 Slitrk4tm1b(KOMP)Wtsi |
HEM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
6.65×10-06 | |
| C1qc C1qcem1(IMPC)J |
HOM | Late adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
7.06×10-06 | |
| Mpi Mpitm1a(EUCOMM)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell EuroPhenome |
7.58×10-06 | |
| Zmym4 Zmym4em1(IMPC)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
7.83×10-06 | |
| Nfatc2ip Nfatc2ipem1(IMPC)Ics |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
7.86×10-06 | |
| Gimap6 Gimap6tm1b(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
8.40×10-06 | |
| Lonrf3 Lonrf3tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
9.17×10-06 | |
| Ube2i Ube2iem1(IMPC)J |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
9.56×10-06 | |
| Lonrf2 Lonrf2em2(IMPC)H |
HOM | Late adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
1.11×10-05 | |
| Borcs6 Borcs6tm1.1(KOMP)Vlcg |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
1.17×10-05 | |
| Dip2b Dip2btm1a(EUCOMM)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI MGP |
1.21×10-05 | |
| Mrap2 Mrap2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
1.26×10-05 | |
| Ttc39a Ttc39atm1b(KOMP)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
1.43×10-05 | |
| Bace2 Bace2tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
1.49×10-05 | |
| Itga8 Itga8tm1b(KOMP)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
1.51×10-05 | |
| Sptlc3 Sptlc3em1(IMPC)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
1.58×10-05 | |
| Grhl3 Grhl3tm1a(EUCOMM)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS EuroPhenome |
1.60×10-05 | |
| Dach2 Dach2em1(IMPC)Ccpcz |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
CCP-IMG IMPC |
1.60×10-05 | |
| Gcgr Gcgrtm1.1(KOMP)Vlcg |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
1.61×10-05 | |
| Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
1.82×10-05 | |
| 4933402N03Rik 4933402N03Riktm2a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
1.91×10-05 | |
| Plekha1 Plekha1tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
2.21×10-05 | |
| Zfp760 Zfp760tm1a(EUCOMM)Hmgu |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU EuroPhenome |
2.30×10-05 | |
| Prelp Prelptm1.1(KOMP)Vlcg |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
2.36×10-05 | |
| Pmpca Pmpcaem1(IMPC)J |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
2.58×10-05 | |
| Gm2a Gm2aem1(IMPC)H |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
2.78×10-05 | |
| Duox2 Duox2em1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
2.92×10-05 | |
| Tcf21 Tcf21em1(IMPC)Mbp |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
3.04×10-05 | |
| Pof1b Pof1bem1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
3.17×10-05 | |
| App Apptm1b(KOMP)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
3.17×10-05 | |
| Tbc1d30 Tbc1d30em1(IMPC)J |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
3.38×10-05 | |
| Gpd1 Gpd1em1(IMPC)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
3.39×10-05 | |
| Nrsn2 Nrsn2em1(IMPC)Kmpc |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
KMPC IMPC |
3.52×10-05 | |
| Samd9l Samd9ltm1.1(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
3.53×10-05 | |
| Sparc Sparctm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI EuroPhenome |
3.54×10-05 | |
| Akt2 Akt2tm1Wcs |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI MGP |
3.58×10-05 | |
| Clcnkb Clcnkbem1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
3.60×10-05 | |
| Cblif Cbliftm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI MGP |
4.03×10-05 | |
| Casp4 Casp4tm1b(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
4.08×10-05 | |
| Chct1 Chct1tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
BCM IMPC |
4.11×10-05 | |
| 1500009L16Rik 1500009L16Rikem1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
4.23×10-05 | |
| Casr Casrtm1b(KOMP)Mbp |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
4.42×10-05 | |
| Dlx3 Dlx3em1(IMPC)Mbp |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
4.87×10-05 | |
| 6430548M08Rik 6430548M08Rikem1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
5.08×10-05 | |
| Mir146 Mir146tm1Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
5.35×10-05 | |
| Ndufs1 Ndufs1tm1b(EUCOMM)Hmgu |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
5.60×10-05 | |
| Lrrc41 Lrrc41em1(IMPC)J |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
5.63×10-05 | |
| Sepsecs Sepsecsem1(IMPC)Tcp |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
TCP IMPC |
5.65×10-05 | |
| Plxnc1 Plxnc1em1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
5.99×10-05 | |
| Cpm Cpmem1(IMPC)Ccpcz |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
CCP-IMG IMPC |
6.05×10-05 | |
| Eftud2 Eftud2tm1b(KOMP)Wtsi |
HET | Late adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
6.09×10-05 | |
| Entr1 Entr1em1(IMPC)Mbp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
UC Davis IMPC |
6.17×10-05 | |
| Abcd3 Abcd3em1(IMPC)J |
HOM | Late adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
6.22×10-05 | |
| Gpc6 Gpc6tm2a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI MGP |
6.46×10-05 | |
| Scarb2 Scarb2em2(IMPC)Tcp |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
TCP IMPC |
6.52×10-05 | |
| Cachd1 Cachd1em1(IMPC)J |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
JAX IMPC |
7.28×10-05 | |
| Car4 Car4tm1b(EUCOMM)Wtsi |
HET | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
7.91×10-05 | |
| Paqr6 Paqr6tm1b(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
BCM IMPC |
8.30×10-05 | |
| Zfp61 Zfp61tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
8.61×10-05 | |
| Erap1 Erap1tm2b(EUCOMM)Wtsi |
HOM | Late adult | increased circulating calcium level | Calcium Clinical Chemistry |
KMPC IMPC |
8.67×10-05 | |
| Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
ICS IMPC |
8.75×10-05 | |
| Rxfp2 Rxfp2tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
HMGU IMPC |
8.94×10-05 | |
| Aqp3 Aqp3tm2b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
MRC Harwell IMPC |
9.40×10-05 | |
| Ninj2 Ninj2tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating calcium level | Calcium Clinical Chemistry |
WTSI IMPC |
9.97×10-05 |