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Phenotype: abnormal rib morphology

Definition
any structural anomaly of the bones forming the bony wall of the chest
Synonyms
rib dysplasia
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal rib morphology

Total number of significant genotype-phenotype associations: 38

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Lrrk1
Lrrk1tm1b(KOMP)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 MRC Harwell
IMPC		 1.54×10-13
Tent5a
Tent5aem1(IMPC)Ccpcz 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 4.16×10-13
Cyp27b1
Cyp27b1tm1b(EUCOMM)Hmgu 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 TCP
IMPC		 9.26×10-13
Slc29a1
Slc29a1tm2b(NCOM)Mfgc 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 TCP
IMPC		 9.26×10-13
Mysm1
Mysm1tm1a(KOMP)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-Ray		 WTSI
EuroPhenome		 5.42×10-09
Ppp5c
Ppp5ctm1a(EUCOMM)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-Ray		 WTSI
EuroPhenome		 3.31×10-08
Prmt7
Prmt7tm1a(EUCOMM)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 WTSI
MGP		 8.01×10-08
Fbn2
Fbn2em1(IMPC)Rbrc 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 RBRC
IMPC		 8.97×10-08
Ppp5c
Ppp5ctm1a(EUCOMM)Wtsi 		HOM Early adult increased rib number Number of ribs left
X-Ray		 WTSI
EuroPhenome		 1.09×10-07
Sik3
Sik3tm1a(EUCOMM)Hmgu 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 WTSI
IMPC		 2.55×10-07
Arl4d
Arl4dtm1a(EUCOMM)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 WTSI
MGP		 3.10×10-07
Dcaf15
Dcaf15tm1a(EUCOMM)Hmgu 		HOM   Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 3.52×10-07
Marveld3
Marveld3em1(IMPC)Ccpcz 		HOM Early adult rib fusion Fusion of ribs
X-ray		 CCP-IMG
IMPC		 2.95×10-06
Brinp3
Brinp3em1(IMPC)Ccpcz 		HOM   Early adult rib fusion Fusion of ribs
X-ray		 CCP-IMG
IMPC		 3.05×10-06
Marveld3
Marveld3em1(IMPC)Ccpcz 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 6.34×10-06
Cst6
Cst6em1(IMPC)Ccpcz 		HET Early adult rib fusion Fusion of ribs
X-ray		 CCP-IMG
IMPC		 8.07×10-06
Dcaf15
Dcaf15tm1a(EUCOMM)Hmgu 		HOM Early adult rib fusion Fusion of ribs
X-ray		 CCP-IMG
IMPC		 8.07×10-06
Brinp3
Brinp3em1(IMPC)Ccpcz 		HOM   Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 1.31×10-05
Lamtor4
Lamtor4em1(IMPC)Ccpcz 		HET   Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 1.38×10-05
Gbx1
Gbx1Gbx1 		HOM Early adult rib fusion Fusion of ribs
X-Ray		 ICS
EuroPhenome		 1.80×10-05
Mta1
Mta1tm1a(EUCOMM)Wtsi 		HOM   Early adult abnormal rib morphology Shape of ribs
X-Ray		 WTSI
EuroPhenome		 2.03×10-05
Klhl5
Klhl5tm1b(EUCOMM)Hmgu 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 2.11×10-05
Pnpt1
Pnpt1tm1a(KOMP)Wtsi 		HET Early adult abnormal rib morphology Shape of ribs
X-ray		 WTSI
EuroPhenome		 2.53×10-05
Cst6
Cst6em1(IMPC)Ccpcz 		HET Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 3.05×10-05
Ntrk2
Ntrk2tm1b(EUCOMM)Wtsi 		HET Early adult abnormal rib morphology Shape of ribs
X-ray		 MRC Harwell
IMPC		 3.23×10-05
Uchl4
Uchl4em1(IMPC)Ccpcz 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 CCP-IMG
IMPC		 3.34×10-05
Prdm14
Prdm14tm1b(EUCOMM)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 BCM
IMPC		 3.41×10-05
Spns2
Spns2tm1a(KOMP)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 WTSI
EuroPhenome		 3.83×10-05
Dscc1
Dscc1tm1a(KOMP)Wtsi 		HOM Early adult abnormal rib morphology Shape of ribs
X-ray		 WTSI
MGP		 9.18×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
X-ray
X-Ray
X-Ray (GMC)

 Phenotype associations stats

0.70% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal rib morphology (24/3405)

0.47% females (16/3389) 0.38% males (13/3400)

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