Phenotype: decreased bone mineral density

Definition reduction in the quatitative measurment value of mineral content of bone; BMD is used as an indicator of bone strength used as a measure of structural strength and screen for osteoporosis; bone mineral density is the ratio of bone mineral content to bone size

Synonyms
  • osteopenia
  • osteopenia
  • decreased bone density
  • decreased bone density
  • decreased BMD
  • reduced BMD
  • reduced bone mineral density
  • reduced bone density
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Related
Synonyms
  • decreased areal bone mineral density
  • decreased areal bone mineral density
  • decreased volumetric bone mineral density
  • decreased volumetric bone mineral density
  • decreased bone mineral density of femur
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MP browserMP:0000063

Phenotype associations stats

4.66% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased bone mineral density (207/4443)

3.77% females (165/4378) 4.01% males (176/4391)

Select a parameter    



Gene variants with decreased bone mineral density

Total number of significant genotype-phenotype associations: 350

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Cyp27b1
Cyp27b1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 0.0
Ghrh
Ghrhtm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 0.0
Myh1
Myh1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 1.4E-45
Ostes
Ostes
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 3.79E-33
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 8.45E-25
Nhlh2
Nhlh2tm1b(KOMP)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 4.08E-24
Mmaa
Mmaaem1(IMPC)J
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 3.29E-21
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 1.24E-20
Postn
Postntm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.52E-20
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.16E-18
Hhatl
Hhatlem1(IMPC)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 5.73E-18
Sh3gl2
Sh3gl2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 1.4E-17
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 6.59E-17
Kiss1r
Kiss1rtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 1.92E-16
P3h1
P3h1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 3.99E-16
Spata22
Spata22tm1b(KOMP)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 1.2E-15
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 1.37E-14
Minar2
Minar2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.7E-14
Ankrd11
Ankrd11Yod
HET Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 5.99E-14
Fbxo11
Fbxo11Jf
HET Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.81E-13
Tram2
Tram2tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 5.13E-13
Tmem189
Tmem189tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 7.63E-13
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 5.67E-12
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.54E-11
Serinc3
Serinc3tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.66E-11
Hook3
Hook3tm1b(NCOM)Mfgc
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 1.77E-11
Kcnj16
Kcnj16tm1Sjtu
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 4.05E-11
Chd2
Chd2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 1.17E-10
Foxk2
Foxk2em1(IMPC)J
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.58E-10
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 2.03E-10
Camsap3
Camsap3tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 2.89E-10
Mlx
Mlxtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 3.75E-10
Sms
Smstm1a(EUCOMM)Wtsi
HEM Male postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 3.79E-10
Pkp4
Pkp4tm1b(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 4.58E-10
Nhlh2
Nhlh2em1(IMPC)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 7.94E-10
Plcg2
Plcg2Ali14
HET Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) HMGU | EuroPhenome 1.48E-9
Trpc3
Trpc3Mwk
HET Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.65E-9
Acp2
Acp2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.89E-9
Slc25a21
Slc25a21tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 2.15E-9
Aktip
Aktiptm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 2.38E-9
Iqgap1
Iqgap1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 2.68E-9
Adnp2
Adnp2em3(IMPC)Tcp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 3.89E-9
Foxo3
Foxo3tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 4.59E-9
Scarb2
Scarb2em2(IMPC)Tcp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 5.27E-9
Tox
Toxtm1b(KOMP)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 6.33E-9
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 8.0E-9
Plod1
Plod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 8.08E-9
Ncald
Ncaldtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 8.59E-9
Rbpms2
Rbpms2em1(IMPC)J
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.01E-8
Caskin1
Caskin1em1(IMPC)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 1.12E-8
Dagla
Daglatm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 1.18E-8
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.2E-8
Parvb
Parvbtm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.68E-8
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.72E-8
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 2.64E-8
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 3.9E-8
Grm7
Grm7em1(IMPC)H
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 3.94E-8
Mir96
Mir96Dmdo
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 4.25E-8
Sdsl
Sdsltm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) ICS | IMPC 4.65E-8
Myo1d
Myo1dem1(IMPC)J
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 4.96E-8
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 5.19E-8
Tnks2
Tnks2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 5.43E-8
Sparc
Sparctm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 5.63E-8
Akt2
Akt2tm1Wcs
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 6.38E-8
Slc9a4
Slc9a4tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 8.04E-8
Ric8b
Ric8btm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 1.03E-7
Ndrg1
Ndrg1tm2b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 1.13E-7
Clvs1
Clvs1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.17E-7
Pxylp1
Pxylp1tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 1.2E-7
Slc4a10
Slc4a10tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 1.31E-7
Cisd2
Cisd2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.43E-7
Hdac8
Hdac8tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | MGP 1.45E-7
Slc20a2
Slc20a2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.46E-7
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 1.5E-7
Umod
Umodurehr4
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) HMGU | EuroPhenome 1.74E-7
Sfrp2
Sfrp2I153N
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.81E-7
2210408I21Rik
2210408I21Riktm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 2.02E-7
Pip4k2c
Pip4k2ctm1b(KOMP)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 2.27E-7
Tlk1
Tlk1tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 2.36E-7
Pttg1
Pttg1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 2.83E-7
Edem3
Edem3tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) KMPC | IMPC 3.15E-7
Farsa
Farsatm2a(EUCOMM)Wtsi
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 3.9E-7
Gna11
Gna11tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 4.03E-7
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 4.11E-7
Colca2
Colca2tm1b(NCOM)Mfgc
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 4.23E-7
Pepd
Pepdtm1a(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 4.35E-7
Pstpip2
Pstpip2em1(IMPC)Tcp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 5.47E-7
Golga5
Golga5tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 5.62E-7
Rbpj
Rbpjtm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 6.55E-7
Rnf169
Rnf169tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 6.83E-7
Alg13
Alg13tm1a(KOMP)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 8.34E-7
Herc1
Herc1em3(IMPC)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 9.0E-7
Tnik
Tniktm3a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 9.87E-7
Brpf1
Brpf1tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 9.88E-7
Ube2j2
Ube2j2em1(IMPC)Rbrc
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) RBRC | IMPC 1.04E-6
Ptp4a1
Ptp4a1em2(IMPC)Tcp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 1.15E-6
AU040320
AU040320em1(IMPC)J
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.16E-6
Dnase2b
Dnase2btm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.2E-6
Pls3
Pls3tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.25E-6
Pycr2
Pycr2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.5E-6
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 1.53E-6
Dolk
Dolkem1(IMPC)J
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.57E-6
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) RBRC | IMPC 1.64E-6
Chn1
Chn1em1(IMPC)J
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.86E-6
Atxn10
Atxn10tm1b(KOMP)Wtsi
HET Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.86E-6
Gse1
Gse1tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 1.87E-6
Sfrp1
Sfrp1tm1Aksh
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 2.29E-6
Stard3nl
STARD3NL
HOM Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) ICS | EuroPhenome 2.31E-6
Cast
Casttm1.1(KOMP)Vlcg
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 2.39E-6
Wnt10b
Wnt10btm1e.1(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 2.4E-6
Prdm14
Prdm14tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) BCM | IMPC 2.48E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) ICS | IMPC 2.7E-6
Adal
Adaltm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 2.85E-6
Dhx40
Dhx40tm1(NCOM)Cmhd
HOM Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) CMHD | EuroPhenome 2.9E-6
Lpin2
Lpin2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 3.14E-6
Tssk5
Tssk5tm1.1(KOMP)Vlcg
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 3.3E-6
Tfap4
Tfap4tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 3.38E-6
Slc5a5
Slc5a5tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 3.54E-6
Nbeal2
Nbeal2tm1a(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 3.92E-6
Prpf31
Prpf31tm1a(EUCOMM)Wtsi
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 3.97E-6
Pbx3
Pbx3tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 4.61E-6
Irx3
Irx3em2(IMPC)H
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 4.85E-6
Tbc1d16
Tbc1d16em1(IMPC)J
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 4.99E-6
Rab3ip
Rab3iptm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 5.04E-6
Fbxo27
Fbxo27em2(IMPC)Marc
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 5.34E-6
Nacc1
Nacc1em1(IMPC)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) HMGU | IMPC 5.51E-6
Miga2
Miga2tm1a(KOMP)Wtsi
HOM Female postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 5.57E-6
Clstn3
Clstn3tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 5.62E-6
Nbr1
Nbr1tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 5.79E-6
Lgmn
Lgmntm1b(NCOM)Mfgc
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 5.84E-6
Eif4g2
Eif4g2tm1b(KOMP)Wtsi
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 5.97E-6
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 6.25E-6
Phex
Phexnot yet available
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) HMGU | EuroPhenome 6.26E-6
Stx8
Stx8tm2a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 6.51E-6
Mcph1
Mcph1tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 6.61E-6
Trim39
Trim39tm1b(EUCOMM)Hmgu
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 6.78E-6
Sh3tc1
Sh3tc1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) ICS | IMPC 7.54E-6
Kmt2a
Kmt2aem1(IMPC)Marc
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 9.44E-6
Sema3f
Sema3ftm1b(EUCOMM)Hmgu
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 9.61E-6
Fam160a1
Fam160a1tm1b(EUCOMM)Wtsi
HET Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.0E-5
Entpd6
Entpd6tm1a(KOMP)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.08E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) RBRC | IMPC 1.13E-5
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) ICS | IMPC 1.25E-5
Stag3
Stag3tm1e.1(KOMP)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.31E-5
Catsperz
Catsperztm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 1.37E-5
Aldh1l1
Aldh1l1em1(IMPC)KMPC
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) KMPC | IMPC 1.41E-5
Aldh3b1
Aldh3b1tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.46E-5
Def6
Def6tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.48E-5
Nab2
Nab2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) ICS | IMPC 1.57E-5
Nisch
Nischtm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 1.6E-5
Krtap17-1
Krtap17-1tm1.1(KOMP)Vlcg
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 1.77E-5
Chd1
Chd1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 1.78E-5
Ndufa10
Ndufa10tm1e.1(EUCOMM)Hmgu
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) HMGU | IMPC 1.81E-5
Csmd1
Csmd1em1(IMPC)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 1.87E-5
Pdcd6ip
Pdcd6ipem1(IMPC)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 2.12E-5
D630023F18Rik
D630023F18Riktm1b(KOMP)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 2.25E-5
Acsbg2
Acsbg2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 2.26E-5
Kdm1a
Kdm1atm1(NCOM)Mfgc
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 2.51E-5
Gtf2a1
Gtf2a1tm1a(KOMP)Wtsi
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 2.64E-5
Rasgrf1
Rasgrf1tm1bNarl
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 2.68E-5
Gfod1
Gfod1tm1b(KOMP)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 3.08E-5
Zfp260
Zfp260tm1b(NCOM)Mfgc
HET Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 3.12E-5
Rab24
Rab24tm1.1(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 3.14E-5
Pank3
Pank3tm1b(KOMP)Mbp
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 3.15E-5
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) ICS | EuroPhenome 3.19E-5
Dcun1d3
Dcun1d3em1(IMPC)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 3.25E-5
Slc22a8
Slc22a8tm1b(KOMP)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 3.93E-5
Gna11
Gna11tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MRC Harwell | IMPC 3.94E-5
Alg9
Alg9em1(IMPC)J
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 3.97E-5
Bbx
Bbxtm1a(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 4.1E-5
Cidec
Cidectm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) HMGU | EuroPhenome 4.21E-5
Adam32
Adam32tm1b(KOMP)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 4.23E-5
Tcf20
Tcf20em1(IMPC)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 4.25E-5
Tppp
Tppptm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 4.37E-5
Prss50
Prss50tm1a(EUCOMM)Hmgu
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 4.45E-5
Tatdn3
Tatdn3tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 4.49E-5
Gpr152
Gpr152tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 4.55E-5
Cbr3
Cbr3em1(IMPC)Ics
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) ICS | IMPC 4.68E-5
Fntb
Fntbtm1b(EUCOMM)Hmgu
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 4.77E-5
Fundc1
Fundc1tm1c(KOMP)Wtsi
HEM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 4.77E-5
Tmem185a
Tmem185atm1a(KOMP)Wtsi
HEM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 4.82E-5
Zbtb45
Zbtb45tm1(NCOM)Cmhd
HOM Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) CMHD | EuroPhenome 4.86E-5
Anks1b
Anks1btm1a(KOMP)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 5.01E-5
BC055324
BC055324tm1a(EUCOMM)Hmgu
HET Female postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 5.11E-5
Hdac8
Hdac8tm1a(EUCOMM)Wtsi
HEM Male postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | MGP 5.26E-5
Setd2
Setd2tm1b(NCOM)Mfgc
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 5.42E-5
Adgrd1
Adgrd1tm1b(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 5.88E-5
Tbc1d30
Tbc1d30em1(IMPC)J
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 6.03E-5
Irx1
Irx1tm1.1(KOMP)Vlcg
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 6.14E-5
Zfyve28
Zfyve28tm1b(EUCOMM)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 6.18E-5
Ehd1
Ehd1tm1a(EUCOMM)Wtsi
HET Female postnatal decreased bone mineral density Dexa-scan analysis | Bone Mineral Density (excluding skull) WTSI | EuroPhenome 6.38E-5
Abcd3
Abcd3em1(IMPC)J
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 6.49E-5
Acer1
Acer1tm1a(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 6.52E-5
Trim8
Trim8em1(IMPC)Wtsi
HOM Female postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) WTSI | IMPC 6.71E-5
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Female Male postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 6.81E-5
Mdk
Mdktm1.1(KOMP)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 6.89E-5
Htr3b
Htr3btm1.1(KOMP)Vlcg
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 7.71E-5
Pla2g7
Pla2g7em1(IMPC)J
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 7.89E-5
Usp47
Usp47tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 8.0E-5
Efna4
Efna4tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 8.01E-5
Cul7
Cul7tm1a(EUCOMM)Wtsi
HET Female postnatal decreased bone mineral density DEXA | Bone Mineral Density (excluding skull) MRC Harwell | EuroPhenome 8.22E-5
Itga8
Itga8tm1b(KOMP)Wtsi
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 8.38E-5
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 8.46E-5
Iqcj
Iqcjem1(IMPC)J
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 8.49E-5
Usp36
Usp36tm1b(EUCOMM)Hmgu
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) MARC | IMPC 8.7E-5
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) HMGU | IMPC 8.78E-5
Fmnl2
Fmnl2em2(IMPC)Tcp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 8.85E-5
Myom1
Myom1em1(IMPC)J
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) JAX | IMPC 9.07E-5
Tox3
Tox3em1(IMPC)Tcp
HET Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 9.25E-5
Crispld2
Crispld2tm1.1(KOMP)Vlcg
HET Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 9.54E-5
Mpz
Mpzem1(IMPC)Tcp
HOM Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) TCP | IMPC 9.65E-5
C9orf72
C9orf72tm1b(KOMP)Mbp
HOM Female Male postnatal decreased bone mineral density Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) UC Davis | IMPC 9.65E-5

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