Significant MP calls for ICS Strains (ICS_001)  

Total number of results: 1755

Gene / Allele	Procedure	Parameter	Zygosity	Sex	Phenotype	P-value	Graph
Stat1 Stat1tm2b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Zranb1 Zranb1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Setx Setxtm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Testes	homozygote		small testis	0.0
Tnfrsf9 Tnfrsf9tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Sun1 Sun1tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Uterus	homozygote		small superior vagus ganglion	0.0
Cdk8 Cdk8tm1b(EUCOMM)Hmgu	Gross Morphology Embryo E9.5	Neural tube closure	homozygote		abnormal neural tube closure	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Hemoglobin	homozygote		decreased hemoglobin content	0.0
Satb1 Satb1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Taf2 Taf2tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Gross Pathology and Tissue Collection	Spleen	hemizygote		abnormal spleen morphology	0.0
Tti2 Tti2tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il18rap Il18raptm1b(KOMP)Wtsi	Fertility of Homozygous Knock-out Mice	Gross Findings Male	homozygote		male infertility	0.0
Cdk8 Cdk8tm1b(EUCOMM)Hmgu	Gross Morphology Embryo E9.5	Embryo turning	homozygote		abnormal embryo turning	0.0
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Small intestine	homozygote		abnormal ileum morphology	0.0
Ctsd Ctsdtm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Small intestine	homozygote		abnormal duodenum morphology	0.0
Stat1 Stat1tm2b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Liver	homozygote		abnormal liver morphology	0.0
Knstrn Knstrntm1b(KOMP)Wtsi	Gross Pathology and Tissue Collection	Seminal vesicle	homozygote		abnormal seminal vesicle morphology	0.0
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Kdm5c Kdm5ctm1d(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Septin3 Septin3tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Myo18b Myo18bem2(IMPC)Ics	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Coq6 Coq6tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Cfap119 Cfap119tm1b(EUCOMM)Hmgu	Fertility of Homozygous Knock-out Mice	Gross Findings Male	homozygote		male infertility	0.0
Atp6v1d Atp6v1dtm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Large intestine	homozygote		abnormal colon morphology	0.0
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Gross Morphology Embryo E9.5	Severely Dysmorphic	homozygote		abnormal embryo development	0.0
Setbp1 Setbp1tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Prkab1 Prkab1tm1b(KOMP)Wtsi	Gross Pathology and Tissue Collection	Eye with optic nerve	homozygote		anophthalmia	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Scaper Scapertm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Med25 Med25tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Sun1 Sun1tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Testes	homozygote		small testis	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Spleen	homozygote		abnormal spleen morphology	0.0
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Fertility of Homozygous Knock-out Mice	Gross Findings Female	homozygote		female infertility	0.0
Pax4 Pax4tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Large intestine	homozygote		abnormal colon morphology	0.0
Raf1 Raf1tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Cdon Cdontm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Setx Setxtm1b(EUCOMM)Wtsi	Fertility of Homozygous Knock-out Mice	Gross Findings Male	homozygote		male infertility	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	0.0
Eftud2 Eftud2tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Nxn Nxntm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Albumin	homozygote		increased circulating serum albumin level	0.0
Timm50 Timm50tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Pigu Pigutm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Brain	heterozygote		hydrocephaly	0.0
Dnm1l Dnm1ltm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Ino80 Ino80tm1a(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Viability E9.5 Secondary Screen	Outcome	homozygote		embryonic lethality prior to organogenesis	0.0
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Hematocrit	homozygote		decreased hematocrit	0.0
Fut4 Fut4em1(IMPC)Ics	Gross Pathology and Tissue Collection	Kidney	homozygote		abnormal kidney morphology	0.0
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Gorasp1 Gorasp1tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean mass	homozygote		increased lean body mass	0.0
Lcp2 Lcp2tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Small intestine	homozygote		abnormal duodenum morphology	0.0
Ddr1 Ddr1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Liver	heterozygote		abnormal liver morphology	0.0
Phf6 Phf6tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Timm50 Timm50tm1b(EUCOMM)Wtsi	Viability E12.5 Secondary Screen	Outcome	homozygote		embryonic lethality prior to tooth bud stage	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		increased lean body mass	0.0
Rbfox1 Rbfox1tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Derl2 Derl2tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Fertility of Homozygous Knock-out Mice	Gross Findings Male	homozygote		male infertility	0.0
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Hematology	Hemoglobin	homozygote		decreased hemoglobin content	0.0
Ino80 Ino80tm1a(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Seminal vesicle	heterozygote		abnormal seminal vesicle morphology	0.0
Dnal4 Dnal4tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Nae1 Nae1tm1b(EUCOMM)Wtsi	Viability E9.5 Secondary Screen	Outcome	homozygote		embryonic lethality prior to organogenesis	0.0
Dcp2 Dcp2tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Thra Thratm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Nae1 Nae1tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Gatad2b Gatad2btm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Otub1 Otub1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
App Apptm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	0.0
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Nab2 Nab2tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Liver	homozygote		abnormal liver morphology	0.0
Ackr3 Ackr3tm2b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Krt8 Krt8tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Prps1 Prps1tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Smc5 Smc5tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Viability E12.5 Secondary Screen	Outcome	homozygote		embryonic lethality prior to tooth bud stage	0.0
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	0.0
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Viability E12.5 Secondary Screen	Outcome	homozygote		embryonic lethality prior to tooth bud stage	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Small intestine	homozygote		abnormal duodenum morphology	0.0
Nae1 Nae1tm1b(EUCOMM)Wtsi	Viability E12.5 Secondary Screen	Outcome	homozygote		embryonic lethality prior to tooth bud stage	0.0
Cbl Cbltm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Nlk Nlktm2b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Morc3 Morc3tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Skin	homozygote		abnormal skin morphology	0.0
Scaper Scapertm1b(EUCOMM)Hmgu	Fertility of Homozygous Knock-out Mice	Gross Findings Male	homozygote		male infertility	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	0.0
Cflar Cflartm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Nab2 Nab2tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Liver	homozygote		abnormal liver morphology	0.0
Pnpla1 Pnpla1tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Parp1 Parp1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Lmna Lmnatm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Sun1 Sun1tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Uterus	homozygote		small superior vagus ganglion	0.0
Stat1 Stat1tm2b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Tgif2 Tgif2tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
4933430I17Rik 4933430I17Riktm1a(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Pancreas	homozygote		abnormal pancreas morphology	0.0
Nrp1 Nrp1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Lca5l Lca5lem1(IMPC)Ics	Fertility of Homozygous Knock-out Mice	Gross Findings Male	homozygote		male infertility	0.0
Pigu Pigutm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Ino80 Ino80tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Cdc26 Cdc26tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Nol8 Nol8tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Mapt Mapttm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Kidney	homozygote		polycystic kidney	0.0
Rwdd3 Rwdd3tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Cdk8 Cdk8tm1b(EUCOMM)Hmgu	Gross Morphology Embryo E9.5	Heart morphology	homozygote		abnormal heart morphology	0.0
Dbn1 Dbn1tm1b(KOMP)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Spleen	homozygote		abnormal spleen morphology	0.0
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Fertility of Homozygous Knock-out Mice	Gross Findings Female	homozygote		female infertility	0.0
Ect2 Ect2tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Setx Setxtm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Testes	homozygote		small testis	0.0
Bmp10 Bmp10tm3b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Skin	homozygote		abnormal skin morphology	0.0
Sun1 Sun1tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Testes	homozygote		small testis	0.0
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Heart	homozygote		abnormal heart morphology	0.0
Pdlim4 Pdlim4em1(IMPC)Ics	Gross Pathology and Tissue Collection	Pancreas	homozygote		abnormal pancreas morphology	0.0
Kctd15 Kctd15tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Aak1 Aak1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Atad2b Atad2btm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Kidney	homozygote		abnormal kidney morphology	0.0
Sun1 Sun1tm1b(EUCOMM)Wtsi	Fertility of Homozygous Knock-out Mice	Gross Findings Male	homozygote		male infertility	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Large intestine	homozygote		abnormal colon morphology	0.0
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Skin	homozygote		abnormal skin morphology	0.0
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Chrna1 Chrna1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Spleen	homozygote		abnormal spleen morphology	0.0
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	0.0
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Large intestine	homozygote		abnormal colon morphology	0.0
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Gross Pathology and Tissue Collection	Kidney	heterozygote		abnormal kidney morphology	0.0
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Skin	homozygote		abnormal skin morphology	0.0
Stat1 Stat1tm2b(EUCOMM)Wtsi	Gross Pathology and Tissue Collection	Lymph node	homozygote		enlarged lymph nodes	0.0
Ncs1 Ncs1tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, incomplete penetrance	0.0
Atp6v1d Atp6v1dtm1b(EUCOMM)Hmgu	Viability E12.5 Secondary Screen	Outcome	homozygote		embryonic lethality prior to tooth bud stage	0.0
Cdk8 Cdk8tm1b(EUCOMM)Hmgu	Viability Primary Screen	Viability Outcome	homozygote		preweaning lethality, complete penetrance	0.0
Sun1 Sun1tm1b(EUCOMM)Wtsi	Fertility of Homozygous Knock-out Mice	Gross Findings Female	homozygote		female infertility	0.0
Cdk8 Cdk8tm1b(EUCOMM)Hmgu	Gross Morphology Embryo E9.5	Embryo Size	homozygote		abnormal embryo size	0.0
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Number of center entries	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Number of center entries	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Center distance travelled	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Center distance travelled	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Distance travelled - total	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Distance travelled - total	homozygote		hyperactivity	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	0.0
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	0.0
Prkdc Prkdcem2(IMPC)Ics	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	0.0
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery average speed	homozygote		hyperactivity	4.203895392974451E-45
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	1.8216880036222622E-44
Prkdc Prkdcem2(IMPC)Ics	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	1.0411647589933391E-42
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	1.0875421329686332E-39
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	1.864587354809102E-39
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	5.253285773953377E-39
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	1.3557283783948205E-38
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery average speed	homozygote		hyperactivity	3.535953868267848E-38
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	2.1072921367262833E-37
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	2.4479693173480584E-37
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	9.860238213675855E-37
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	2.9169064719992422E-36
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	5.8038953787305776E-36
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	1.2803895719987588E-35
Mmp9 Mmp9tm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	1.0479636600457573E-34
Mmp9 Mmp9tm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	6.394987274658277E-34
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	5.976280135821713E-33
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	3.392258642271044E-32
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	7.220984684671898E-31
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	7.651647728796218E-31
Prkdc Prkdcem2(IMPC)Ics	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	2.023420217245564E-29
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	8.138768694539684E-29
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	1.1064591560393089E-26
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	2.2881845787516442E-26
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Rotarod	Latency to fall mean	homozygote		abnormal motor capabilities/coordination/movement	4.667917081851769E-26
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Right outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	4.819202114545693E-26
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	5.429913267315721E-26
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Left outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	3.576636179704176E-25
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.5838638814500744E-24
Prkdc Prkdcem2(IMPC)Ics	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	5.238827638155455E-24
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Center resting time	homozygote		decreased locomotor activity	1.0856354264749499E-23
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Indirect Calorimetry	Total water intake	homozygote		increased fluid intake	2.126859246163405E-23
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Periphery distance travelled	homozygote		hyperactivity	6.586436987050518E-23
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Neutrophil cell count	heterozygote		increased neutrophil cell number	6.62713589887268E-23
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery distance travelled	homozygote		hyperactivity	6.929993484338959E-23
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	1.5212588071609038E-22
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	2.383193728189838E-22
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	3.039153911421945E-22
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	4.249933727030177E-22
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.0491675354080605E-21
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.0491675354080605E-21
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Unexpected behaviors	homozygote		abnormal behavior	1.2448923825822975E-21
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Head bobbing	homozygote		head bobbing	1.2448923825822975E-21
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Startle response	homozygote		abnormal startle reflex	1.2448923825822975E-21
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	1.3934761137508772E-21
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Left outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	3.599089098509149E-21
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	3.984926445102872E-21
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	6.780931009264219E-21
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Periphery average speed	homozygote		hyperactivity	4.8686849190848196E-20
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	7.77302138603963E-20
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Skin color - tail	homozygote		abnormal skin coloration	1.0288792991421923E-19
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.1521206801125264E-19
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	1.188563026727345E-19
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Skin color - tail	homozygote		abnormal skin coloration	1.2687735675038757E-19
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	3.704710353053496E-19
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	8.67409611066355E-19
Prkdc Prkdcem2(IMPC)Ics	Hematology	Lymphocyte cell count	homozygote		decreased lymphocyte cell number	1.3920717654425346E-18
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.9423710387363E-18
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Aspartate aminotransferase	homozygote		increased circulating aspartate transaminase level	2.2353795048082024E-18
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Number of rears - total	homozygote		increased vertical activity	6.710502305746131E-18
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Open Field	Whole arena resting time	heterozygote		decreased locomotor activity	6.854817198495807E-18
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Unexpected behaviors	homozygote		abnormal behavior	1.0871313844706772E-17
Cav1 Cav1em2(IMPC)Ics	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	1.1318032734516035E-17
Morc3 Morc3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alanine aminotransferase	heterozygote		increased circulating alanine transaminase level	1.341372707646302E-17
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Right outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	2.3397574558393287E-17
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	2.6365683884690762E-17
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		hyperactivity	5.1305288541005404E-17
Thra Thratm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	5.560087716666268E-17
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	8.016723476953624E-17
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	8.448839320228876E-17
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Startle response	heterozygote		abnormal startle reflex	1.0517514800083551E-16
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	homozygote		decreased prepulse inhibition	1.149962634136776E-16
Prkdc Prkdcem2(IMPC)Ics	Hematology	White blood cell count	homozygote		decreased leukocyte cell number	1.334699461141755E-16
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Forelimb digit - size	homozygote		abnormal digit morphology	1.3729141466505208E-16
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Forelimb digit - shape	homozygote		abnormal digit morphology	1.3729141466505208E-16
Mmp9 Mmp9tm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	2.26660219803518E-16
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery distance travelled	homozygote		hyperactivity	2.4498953632606823E-16
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Open Field	Periphery resting time	heterozygote		decreased locomotor activity	2.773340188125657E-16
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Total protein	homozygote		decreased circulating total protein level	3.766981568357672E-16
Aak1 Aak1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	4.271703090638092E-16
Aak1 Aak1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	7.23324897038553E-16
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Alkaline phosphatase	homozygote		decreased circulating alkaline phosphatase level	1.1439427709806398E-15
Lat Latem1(IMPC)Ics	Combined SHIRPA and Dysmorphology	Startle response	homozygote		abnormal startle reflex	1.2436783594209919E-15
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Startle response	homozygote		abnormal startle reflex	1.2436783594209919E-15
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	1.8394885342997184E-15
Mmp9 Mmp9tm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	2.580399688207843E-15
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Aspartate aminotransferase	homozygote		increased circulating aspartate transaminase level	3.4528741170658734E-15
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Periphery distance travelled	homozygote		hyperactivity	4.341682517520519E-15
Aak1 Aak1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	4.805727400091419E-15
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		hyperactivity	5.017197645702928E-15
Rnf10 Rnf10tm1b(KOMP)Wtsi	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	5.510820071759001E-15
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	6.3298407924146545E-15
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	9.45195341401717E-15
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Neutrophil differential count	heterozygote		increased neutrophil cell number	1.3382954548160284E-14
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Percentage center movement time	homozygote		decreased anxiety-related response	1.645986949169731E-14
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	1.894321254491873E-14
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	2.4427340914443853E-14
Prkdc Prkdcem2(IMPC)Ics	Hematology	Lymphocyte cell count	homozygote		decreased lymphocyte cell number	2.6594447604939668E-14
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Lymphocyte differential count	heterozygote		decreased lymphocyte cell number	3.6284824699982926E-14
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Monocyte differential count	heterozygote		increased monocyte cell number	3.9036394288479576E-14
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Center permanence time	homozygote		decreased thigmotaxis	4.2363231385301667E-14
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Percentage center time	homozygote		abnormal behavior	4.2363231385301667E-14
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery permanence time	homozygote		decreased thigmotaxis	4.2363231385301667E-14
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	4.259833723827336E-14
Nab2 Nab2tm1b(EUCOMM)Hmgu	Fear Conditioning	% Cue freezing total	homozygote		abnormal cued conditioning behavior	4.4615166731399106E-14
Aak1 Aak1tm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	4.7024409648328824E-14
Pdpr Pdprtm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	4.852094407140593E-14
Otub1 Otub1tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	5.952856751371277E-14
Mx2 Mx2em1(IMPC)Ics	Combined SHIRPA and Dysmorphology	Startle response	homozygote		abnormal startle reflex	6.995690512339239E-14
Aak1 Aak1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	7.078392776430076E-14
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	7.848864787274312E-14
Plscr1 Plscr1tm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	8.155033316388852E-14
Mapt Mapttm1b(EUCOMM)Hmgu	Eye Morphology	Retinal Blood Vessels Pattern	homozygote		abnormal retina blood vessel morphology	8.416176962159141E-14
Mapt Mapttm1b(EUCOMM)Hmgu	Eye Morphology	Retinal Blood Vessels	homozygote		abnormal retina vasculature morphology	8.416176962159141E-14
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Percentage center movement time	homozygote		decreased anxiety-related response	1.4305188435724536E-13
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	1.5817928293148514E-13
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery resting time	homozygote		hyperactivity	1.6415937619668197E-13
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	homozygote		decreased prepulse inhibition	1.6937680099617103E-13
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	1.7428648856152723E-13
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Number of rears - total	hemizygote		increased vertical activity	2.2681856393091948E-13
Dnajc5b Dnajc5btm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	2.5029579645875766E-13
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Center average speed	hemizygote		hyperactivity	2.757793993168889E-13
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Whole arena resting time	homozygote		hyperactivity	2.893459668910914E-13
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Left outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	3.1482745555498626E-13
Rnf10 Rnf10tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Unexpected behaviors	homozygote		abnormal behavior	3.1925915904007507E-13
Aak1 Aak1tm1b(EUCOMM)Hmgu	Open Field	Number of rears - total	homozygote		increased vertical activity	3.20858167509111E-13
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	3.2750432682644715E-13
Timm50 Timm50tm1b(EUCOMM)Wtsi	Clinical Chemistry	Alanine aminotransferase	heterozygote		increased circulating alanine transaminase level	3.8915523364532745E-13
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	5.442431444749318E-13
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Albumin	heterozygote		increased circulating serum albumin level	5.469784781358955E-13
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	HDL-cholesterol	homozygote		increased circulating HDL cholesterol level	5.487832410722149E-13
Aak1 Aak1tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		short tibia	6.516513132055757E-13
Gpr101 Gpr101tm1b(KOMP)Mbp	Open Field	Center resting time	homozygote		decreased locomotor activity	7.150222796660499E-13
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Left outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	9.22151244253655E-13
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	1.0099792096401883E-12
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	1.0994378150941397E-12
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Center average speed	homozygote		hyperactivity	1.5796253194366727E-12
Cav1 Cav1em2(IMPC)Ics	Clinical Chemistry	HDL-cholesterol	homozygote		increased circulating HDL cholesterol level	1.6992862195489011E-12
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery resting time	homozygote		hyperactivity	1.933653541105751E-12
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Monocyte cell count	heterozygote		increased monocyte cell number	2.0805785479888206E-12
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	2.4865513294225483E-12
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	2.7195812875996372E-12
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Number of rears - total	homozygote		increased vertical activity	2.720792124585869E-12
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Calcium	heterozygote		increased circulating calcium level	2.8711072148218664E-12
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Periphery distance travelled	heterozygote		hyperactivity	3.4245655356618387E-12
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	Alkaline phosphatase	homozygote		decreased circulating alkaline phosphatase level	3.664896511268445E-12
Prkdc Prkdcem2(IMPC)Ics	Hematology	White blood cell count	homozygote		decreased leukocyte cell number	4.004995120265864E-12
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	4.297952618803613E-12
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean/Body weight	heterozygote		increased lean body mass	4.5775232562772494E-12
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	4.702976289655547E-12
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Periphery average speed	heterozygote		hyperactivity	5.300459290230597E-12
Iah1 Iah1tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	ST	homozygote		prolonged ST segment	5.379882303535588E-12
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Percentage center time	homozygote		abnormal behavior	6.485515683524179E-12
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Periphery permanence time	homozygote		decreased thigmotaxis	6.485516550885917E-12
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Center permanence time	homozygote		decreased thigmotaxis	6.485516550885917E-12
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Hindpaw - shape	homozygote		abnormal autopod morphology	6.845509402386707E-12
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Forepaw - shape	homozygote		abnormal autopod morphology	6.845509402386707E-12
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Whole arena average speed	heterozygote		hyperactivity	7.966606541121024E-12
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Locomotor activity	homozygote		decreased exploration in new environment	8.005322099657874E-12
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	BMC/Body weight	homozygote		decreased bone mineral content	8.210415854137398E-12
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	9.04498698162115E-12
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	X-ray	Tibia length	homozygote		short tibia	9.734890844825816E-12
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		decreased total body fat amount	1.1687428802531485E-11
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	1.1969980562298588E-11
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	1.2105929106387414E-11
Eftud2 Eftud2tm1b(KOMP)Wtsi	Echo	LVAWd	heterozygote		increased heart left ventricle size	1.468936777770935E-11
Carmil2 Carmil2tm1b(KOMP)Mbp	Combined SHIRPA and Dysmorphology	Coat - color - abdomen	homozygote		abnormal coat/hair pigmentation	1.6260062740691694E-11
Carmil2 Carmil2tm1b(KOMP)Mbp	Combined SHIRPA and Dysmorphology	Coat - color - head	homozygote		abnormal coat/hair pigmentation	1.6260062740691694E-11
Carmil2 Carmil2tm1b(KOMP)Mbp	Combined SHIRPA and Dysmorphology	Coat - color - back	homozygote		abnormal coat/hair pigmentation	1.6260062740691694E-11
Atad2b Atad2btm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		long tibia	1.7175027025584377E-11
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	homozygote		decreased prepulse inhibition	1.7358578116577483E-11
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	2.2252866216376788E-11
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	2.241584695639176E-11
4933430I17Rik 4933430I17Riktm1b(EUCOMM)Wtsi	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	2.2638498714533384E-11
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Ears	homozygote		abnormal ear morphology	2.2938565977237424E-11
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	2.7926905579733763E-11
Morc3 Morc3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Aspartate aminotransferase	heterozygote		increased circulating aspartate transaminase level	2.9574717674840656E-11
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Contact righting	homozygote		impaired righting response	2.964814158068485E-11
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Total protein	homozygote		decreased circulating total protein level	3.0325731509295295E-11
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	3.09037101464682E-11
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Distance travelled - total	homozygote		hyperactivity	3.1013542428626195E-11
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Distance travelled - total	homozygote		hyperactivity	3.117961444587536E-11
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	3.268856019200683E-11
Nxn Nxntm1b(EUCOMM)Wtsi	Open Field	Whole arena resting time	heterozygote		decreased locomotor activity	3.780276092157919E-11
Sdsl Sdsltm1b(EUCOMM)Hmgu	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	3.911630741537664E-11
Ctsd Ctsdtm1b(EUCOMM)Wtsi	Clinical Chemistry	Aspartate aminotransferase	heterozygote		increased circulating aspartate transaminase level	4.483953833234189E-11
Laptm4a Laptm4atm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	4.8071019387307956E-11
Spn Spnem1(IMPC)Ics	Body Composition (DEXA lean/fat)	Lean mass	homozygote		decreased lean body mass	5.2523211474531095E-11
Mx2 Mx2em1(IMPC)Ics	Eye Morphology	Left vitreous humour thickness	homozygote		abnormal vitreous body morphology	5.2523905363921486E-11
Mx2 Mx2em1(IMPC)Ics	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	6.190106760506353E-11
Thra Thratm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	7.851961442151278E-11
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Fat mass	heterozygote		decreased total body fat amount	8.203211721014014E-11
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	homozygote		decreased prepulse inhibition	8.81821907161573E-11
Nxn Nxntm1b(EUCOMM)Wtsi	Open Field	Periphery resting time	heterozygote		decreased locomotor activity	9.545850221392982E-11
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Mineral Density (excluding skull)	homozygote		decreased bone mineral density	1.0728896937539645E-10
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	1.4436038475729163E-10
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Right outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	1.4487899768766965E-10
Mapt Mapttm1b(EUCOMM)Hmgu	Eye Morphology	Persistence of hyaloid vascular system	homozygote		persistence of hyaloid vascular system	1.4498267864038183E-10
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	1.496106571963196E-10
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	HDL-cholesterol	heterozygote		increased circulating HDL cholesterol level	1.5021917043611666E-10
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	homozygote		increased lymphocyte cell number	1.5557861943182871E-10
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Hindlimb digit - shape	homozygote		abnormal digit morphology	1.6551701675915353E-10
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Hindlimb digit - size	homozygote		abnormal digit morphology	1.6551701675915353E-10
Cstb Cstbtm1b(EUCOMM)Wtsi	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	1.7578111188853995E-10
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Trunk curl	homozygote		trunk curl	1.7720806766430286E-10
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Open Field	Center resting time	homozygote		decreased locomotor activity	1.8211113173016713E-10
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	2.0787083165885178E-10
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Distance travelled - total	heterozygote		hyperactivity	2.2562365864509104E-10
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	2.2754487183362926E-10
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	2.3693852435613394E-10
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	CD8 CD44+CD62L+ T cells	homozygote		increased effector memory CD8-positive, alpha-beta T cell number	2.385627251300093E-10
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	2.583243063902785E-10
Smc5 Smc5tm1b(KOMP)Wtsi	Hematology	Neutrophil cell count	heterozygote		increased neutrophil cell number	2.7102270427903363E-10
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Right outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	3.0085911539856625E-10
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	3.300276718576356E-10
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	3.332328579741528E-10
Mapt Mapttm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	3.680311333464914E-10
Iah1 Iah1tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QT	homozygote		prolonged QT interval	3.760875777469863E-10
Aak1 Aak1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Area	homozygote		abnormal bone structure	3.8036862548551653E-10
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Right vitreous humor thickness	homozygote		abnormal vitreous body morphology	3.8751418740545773E-10
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Periphery permanence time	homozygote		decreased thigmotaxis	4.1253769844651345E-10
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Center permanence time	homozygote		decreased thigmotaxis	4.1253769844651345E-10
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Percentage center time	homozygote		abnormal behavior	4.1253769844651345E-10
Lca5l Lca5lem1(IMPC)Ics	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	4.4191267312143623E-10
Il18rap Il18raptm1b(KOMP)Wtsi	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	4.5047315877511096E-10
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Whole arena average speed	homozygote		hyperactivity	4.522342500479226E-10
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Distance travelled - total	hemizygote		hyperactivity	4.533306785514668E-10
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Persistence of hyaloid vascular system	homozygote		persistence of hyaloid vascular system	4.695331901061195E-10
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	White blood cell count	homozygote		increased leukocyte cell number	5.161590044266973E-10
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.247645096240205E-10
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.247645096240205E-10
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Total cholesterol	heterozygote		increased circulating cholesterol level	5.362487121018944E-10
Pdpr Pdprtm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	5.733047370171107E-10
Gpr108 Gpr108tm1b(EUCOMM)Hmgu	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	6.030737020878973E-10
Bace2 Bace2tm1b(EUCOMM)Wtsi	Eye Morphology	Retina (combined)	homozygote		abnormal retina morphology	6.0517613142963E-10
Bace2 Bace2tm1b(EUCOMM)Wtsi	Eye Morphology	Retina (combined)	homozygote		abnormal retina morphology	6.0517613142963E-10
Smc5 Smc5tm1b(KOMP)Wtsi	Hematology	Lymphocyte differential count	heterozygote		decreased lymphocyte cell number	6.070968172622315E-10
Il2ra Il2ratm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	6.257327433978332E-10
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Periphery average speed	homozygote		hyperactivity	6.27895457849803E-10
Prkdc Prkdcem2(IMPC)Ics	Hematology	Eosinophil differential count	homozygote		increased eosinophil cell number	6.466169266694521E-10
Rnf10 Rnf10tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	6.876628710905663E-10
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Open Field	Distance travelled - total	heterozygote		decreased locomotor activity	7.281253378010888E-10
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu	Hematology	Eosinophil differential count	heterozygote		increased eosinophil cell number	7.306667493267582E-10
Plscr1 Plscr1tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	7.688067960032186E-10
Setx Setxtm1b(EUCOMM)Wtsi	Immunophenotyping	Monocytes	homozygote		increased monocyte cell number	7.837571702751234E-10
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean mass	heterozygote		increased lean body mass	7.914163768774074E-10
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	HDL-cholesterol	heterozygote		increased circulating HDL cholesterol level	9.137020029470477E-10
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		hyperactivity	9.755614094331122E-10
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) differential count	homozygote		increased large unstained cell number	9.99914151478265E-10
Rab19 Rab19tm1b(EUCOMM)Hmgu	Heart Weight	Heart weight	homozygote		increased heart weight	1.00001806835337E-9
Spn Spnem1(IMPC)Ics	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		decreased lean body mass	1.001115301768607E-9
Med25 Med25tm1b(KOMP)Wtsi	Heart Weight	Tibia length	heterozygote		short tibia	1.0795613292202688E-9
Cdkl5 Cdkl5tm1dIcs	Indirect Calorimetry	Respiratory Exchange Ratio	hemizygote		decreased respiratory quotient	1.1501966046267853E-9
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Right inner nuclear layer	heterozygote		abnormal retina inner nuclear layer morphology	1.2135205063046328E-9
Capn10 Capn10tm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	1.2200976895471172E-9
Ppp4c Ppp4cem1(IMPC)Ics	Heart Weight	Heart weight	heterozygote		increased heart weight	1.2631135026808238E-9
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.2730342335842693E-9
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Gait	homozygote		abnormal gait	1.2946215210973833E-9
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	1.3105607710173217E-9
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI1	homozygote		decreased prepulse inhibition	1.3384059416310379E-9
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	1.3574482649048036E-9
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	1.3921080954659715E-9
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	1.4852892249450633E-9
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Area	homozygote		abnormal bone structure	1.5478007764357926E-9
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	1.5661322239068909E-9
Smc5 Smc5tm1b(KOMP)Wtsi	Hematology	Neutrophil differential count	heterozygote		increased neutrophil cell number	1.7172321342684427E-9
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	1.747616495961779E-9
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	1.8449035632528421E-9
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Fat mass	homozygote		decreased total body fat amount	1.9431791731250314E-9
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Clinical Chemistry	Aspartate aminotransferase	homozygote		increased circulating aspartate transaminase level	1.964345797134115E-9
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	1.996602883025389E-9
Dgkk Dgkkem1(IMPC)Ics	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	hemizygote		increased startle reflex	2.157661604940131E-9
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Whole arena average speed	heterozygote		hyperactivity	2.182724445631834E-9
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	2.21953655454854E-9
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Forepaw - shape	homozygote		abnormal autopod morphology	2.3473800681017565E-9
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Hindpaw - shape	homozygote		abnormal autopod morphology	2.3473800681017565E-9
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	X-ray	Tibia length	homozygote		short tibia	2.3561759210366517E-9
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	HDL-cholesterol	homozygote		increased circulating HDL cholesterol level	2.411750577024918E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - abdomen	homozygote		abnormal coat/hair pigmentation	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - head	homozygote		abnormal coat appearance	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - abdomen	homozygote		abnormal coat/hair pigmentation	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - back	homozygote		abnormal coat/hair pigmentation	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - abdomen	homozygote		abnormal coat appearance	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - back	homozygote		abnormal coat appearance	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - back	homozygote		abnormal coat/hair pigmentation	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - head	homozygote		abnormal coat/hair pigmentation	2.6596547186841235E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - head	homozygote		abnormal coat/hair pigmentation	2.6596547186841235E-9
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Eosinophil cell count	homozygote		increased eosinophil cell number	2.7762587784252446E-9
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	2.7938702462648735E-9
Capn10 Capn10tm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	2.796241238556263E-9
Ino80 Ino80tm1a(EUCOMM)Hmgu	Open Field	Whole arena average speed	heterozygote		decreased locomotor activity	2.8360147563688543E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - head	homozygote		abnormal coat/hair pigmentation	2.9527822409392E-9
Dcp2 Dcp2tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - head	heterozygote		abnormal coat/hair pigmentation	2.9527822409392E-9
Dcp2 Dcp2tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - back	heterozygote		abnormal coat/hair pigmentation	2.9527822409392E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - head	homozygote		abnormal coat/hair pigmentation	2.9527822409392E-9
Il2ra Il2ratm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration pre-cue-1	homozygote		abnormal freezing behavior	2.9711861859738065E-9
Spn Spnem1(IMPC)Ics	Body Composition (DEXA lean/fat)	Fat mass	homozygote		increased total body fat amount	2.9960238734361155E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - head	homozygote		abnormal coat appearance	3.0071478640536498E-9
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	3.0975824127921214E-9
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Periphery distance travelled	homozygote		decreased locomotor activity	3.211877208642022E-9
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Whole arena resting time	homozygote		decreased locomotor activity	3.3754108397232585E-9
Prkdc Prkdcem2(IMPC)Ics	Hematology	Eosinophil differential count	homozygote		increased eosinophil cell number	3.4235518864278447E-9
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Periphery resting time	homozygote		decreased locomotor activity	3.574183837784517E-9
Casq1 Casq1tm1b(EUCOMM)Wtsi	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	3.780404878028776E-9
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Hematology	Neutrophil differential count	heterozygote		increased neutrophil cell number	4.192350022691471E-9
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		decreased total body fat amount	4.22727364224329E-9
Iqce Iqcetm1b(EUCOMM)Hmgu	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	4.303733369681595E-9
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Retina (combined)	homozygote		abnormal retina morphology	4.311880186236294E-9
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	4.788188956439399E-9
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Total cholesterol	heterozygote		increased circulating cholesterol level	4.933488728653401E-9
Tti2 Tti2tm1b(KOMP)Wtsi	Hematology	Neutrophil differential count	heterozygote		increased neutrophil cell number	5.006439263155471E-9
Dnajc5b Dnajc5btm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	ST	homozygote		shortened ST segment	5.150420090416219E-9
Ino80 Ino80tm1a(EUCOMM)Hmgu	Open Field	Periphery average speed	heterozygote		decreased locomotor activity	5.172031247724362E-9
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Hematology	Lymphocyte differential count	heterozygote		decreased lymphocyte cell number	5.3389688225990994E-9
Thra Thratm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	5.675599989984903E-9
Thra Thratm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	5.697122773540286E-9
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.748038489628016E-9
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.748038489628016E-9
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	6.037139677061987E-9
Tiam1 Tiam1tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	6.073993308319814E-9
Nol8 Nol8tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		increased startle reflex	6.455358469992234E-9
Pdpr Pdprtm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	homozygote		improved glucose tolerance	6.469428104338704E-9
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Open Field	Periphery distance travelled	heterozygote		decreased locomotor activity	6.5296275053583486E-9
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Number of rears - total	homozygote		decreased vertical activity	6.773327676512508E-9
Icos Icostm2b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	7.024493875462667E-9
Aak1 Aak1tm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	7.299575610630882E-9
Cx3cl1 Cx3cl1em3(IMPC)Ics	Indirect Calorimetry	Respiratory Exchange Ratio	homozygote		increased respiratory quotient	7.335291485333073E-9
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Eye Morphology	Retinal Blood Vessels	heterozygote		abnormal retina vasculature morphology	7.359192810696413E-9
Gpr101 Gpr101tm1b(KOMP)Mbp	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	7.549342484480803E-9
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	hemizygote		abnormal auditory brainstem response	7.59233031999429E-9
Lat Latem1(IMPC)Ics	Eye Morphology	Left vitreous humour thickness	homozygote		abnormal vitreous body morphology	7.601577145521787E-9
Cfap119 Cfap119tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	7.805172508312808E-9
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Indirect Calorimetry	Respiratory Exchange Ratio	homozygote		decreased respiratory quotient	7.94413423932383E-9
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Distance travelled - total	homozygote		decreased locomotor activity	8.158505870881072E-9
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Eye Morphology	Retinal Blood Vessels Pattern	heterozygote		abnormal retina blood vessel morphology	8.360223624492846E-9
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	8.646287241731443E-9
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	8.7894704847713E-9
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	8.869236900466149E-9
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Periphery average speed	heterozygote		hyperactivity	9.06601904659965E-9
Bnc2 Bnc2tm1b(KOMP)Wtsi	Eye Morphology	Right corneal thickness	heterozygote		increased cornea thickness	9.643667198133699E-9
Sun1 Sun1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	9.75878844400313E-9
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	1.0030728248011656E-8
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Albumin	heterozygote		increased circulating serum albumin level	1.0412567696960195E-8
Atad2b Atad2btm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	1.0465715405416631E-8
Il2ra Il2ratm1b(EUCOMM)Wtsi	X-ray	Shape of vertebrae	homozygote		abnormal vertebrae morphology	1.1423186840886501E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	1.1613765948936816E-8
Sun1 Sun1tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		decreased lean body mass	1.1835946445160062E-8
Aak1 Aak1tm1b(EUCOMM)Hmgu	Open Field	Number of rears - total	homozygote		increased vertical activity	1.189023990377791E-8
Prkdc Prkdcem2(IMPC)Ics	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	1.191867315952777E-8
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Retina (combined)	homozygote		abnormal retina morphology	1.2438028385020061E-8
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	1.3369698237397643E-8
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	1.3419038324968824E-8
Obp2a Obp2atm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - head	homozygote		abnormal coat/hair pigmentation	1.3729573034026998E-8
Obp2a Obp2atm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - abdomen	homozygote		abnormal coat/hair pigmentation	1.3729573034026998E-8
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Distance travelled - total	heterozygote		hyperactivity	1.389243831084741E-8
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	1.3913967755740941E-8
Rab19 Rab19tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) differential count	homozygote		decreased large unstained cell number	1.4252796276537083E-8
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	1.4360749922559535E-8
Dcp2 Dcp2tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - abdomen	heterozygote		abnormal coat/hair pigmentation	1.4709356399578155E-8
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	1.4713706697477846E-8
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	1.5828046429078313E-8
Cidea Cideatm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	1.597407006670437E-8
Atad2b Atad2btm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		long tibia	1.6825966397959746E-8
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Glucose	homozygote		decreased circulating glucose level	1.69143667960725E-8
Rnf10 Rnf10tm1b(KOMP)Wtsi	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	1.7043404909600213E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	1.7253768191949348E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Glucose	homozygote		increased circulating glucose level	1.7264266460870203E-8
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.7580855882215474E-8
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	1.762307277886066E-8
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Whole arena resting time	homozygote		hyperactivity	1.8029785664452902E-8
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	1.8568323767453876E-8
Sun1 Sun1tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		increased total body fat amount	2.0230354280670326E-8
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	HDL-cholesterol	homozygote		decreased circulating HDL cholesterol level	2.2655529008375197E-8
Plscr1 Plscr1tm1b(EUCOMM)Hmgu	Eye Morphology	Right outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	2.2766332818946466E-8
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) count	heterozygote		increased large unstained cell number	2.4343135507365332E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Albumin	homozygote		increased circulating serum albumin level	2.4769725825990463E-8
Ino80 Ino80tm1a(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Locomotor activity	heterozygote		decreased exploration in new environment	2.4817556010248154E-8
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	2.566681445159702E-8
Rnf10 Rnf10tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	2.6140730469137452E-8
Casq1 Casq1tm1b(EUCOMM)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	2.6300012834212794E-8
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Locomotor activity	homozygote		decreased exploration in new environment	2.719067637713124E-8
Iqce Iqcetm1b(EUCOMM)Hmgu	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	2.731605164285611E-8
Prkab1 Prkab1tm1b(KOMP)Wtsi	Heart Weight	Heart weight	homozygote		increased heart weight	2.7507153887995628E-8
Exd1 Exd1tm1b(EUCOMM)Hmgu	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	2.775146690225938E-8
Cfap119 Cfap119tm1b(EUCOMM)Hmgu	Clinical Chemistry	HDL-cholesterol	homozygote		increased circulating HDL cholesterol level	2.7754268216995115E-8
Dnajc5b Dnajc5btm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QT	homozygote		shortened QT interval	2.7787640632936927E-8
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	2.9122547928750464E-8
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Platelet count	homozygote		thrombocytopenia	2.940814169960504E-8
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	3.042586271817527E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	3.072842957863031E-8
Plekhg3 Plekhg3tm1b(EUCOMM)Hmgu	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	3.08445002872304E-8
Med25 Med25tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	3.114931956815781E-8
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QRS	homozygote		prolonged QRS complex duration	3.340913679039659E-8
Gpr108 Gpr108tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		short tibia	3.5430716138762364E-8
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	3.56657814393202E-8
Cd19 Cd19em2(IMPC)Ics	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	3.801267567382638E-8
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	3.902115253140437E-8
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Echo	HR	homozygote		increased heart rate	3.9087034053864045E-8
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair distribution - abdomen	homozygote		abnormal coat/ hair morphology	3.9608018198578065E-8
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Center average speed	heterozygote		hyperactivity	4.118621532711586E-8
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	4.423364075023528E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	4.5944563709099384E-8
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) count	heterozygote		increased large unstained cell number	4.6526828612059035E-8
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	4.741612613656798E-8
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	4.894411631539697E-8
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Platelet count	homozygote		thrombocytopenia	4.899396444102422E-8
Carmil2 Carmil2tm1b(KOMP)Mbp	Combined SHIRPA and Dysmorphology	Coat - color - back	homozygote		abnormal coat/hair pigmentation	4.9799950829765294E-8
Carmil2 Carmil2tm1b(KOMP)Mbp	Combined SHIRPA and Dysmorphology	Coat - color - head	homozygote		abnormal coat/hair pigmentation	4.9799950829765294E-8
Carmil2 Carmil2tm1b(KOMP)Mbp	Combined SHIRPA and Dysmorphology	Coat - color - abdomen	homozygote		abnormal coat/hair pigmentation	4.9799950829765294E-8
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Alkaline phosphatase	homozygote		decreased circulating alkaline phosphatase level	5.063615304834457E-8
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Number of center entries	homozygote		hyperactivity	5.162498339927879E-8
Nae1 Nae1tm1b(EUCOMM)Wtsi	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	5.3088147211610703E-8
Aak1 Aak1tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		short tibia	5.418434056991828E-8
Bmp10 Bmp10tm3b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	heterozygote		improved glucose tolerance	5.607490294323725E-8
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Clinical Chemistry	Glucose	homozygote		decreased circulating glucose level	5.6364459766200525E-8
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Bone Mineral Content (excluding skull)	heterozygote		decreased bone mineral content	5.636725930457942E-8
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Hindlimb nail - length	homozygote		abnormal nail morphology	5.663578761527788E-8
App Apptm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	6.340549418837327E-8
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	6.47253699526118E-8
Nxn Nxntm1b(EUCOMM)Wtsi	Open Field	Distance travelled - total	heterozygote		decreased locomotor activity	6.621592518740727E-8
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Left inner nuclear layer	heterozygote		abnormal retina inner nuclear layer morphology	6.623172765785057E-8
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Eye Morphology	Right outer nuclear layer	heterozygote		abnormal retina outer nuclear layer morphology	6.727538703898972E-8
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	6.819245612632585E-8
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Total protein	heterozygote		increased circulating total protein level	7.081584385559836E-8
Plscr1 Plscr1tm1b(EUCOMM)Hmgu	Eye Morphology	Left outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	7.089563069939686E-8
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	7.251400546692821E-8
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Mineral Content (excluding skull)	homozygote		decreased bone mineral content	7.506959320835449E-8
Rab19 Rab19tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) count	homozygote		decreased large unstained cell number	7.658653089492873E-8
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	7.691717485158733E-8
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	7.742339391825226E-8
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Hemoglobin	homozygote		decreased hemoglobin content	7.830052339841131E-8
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	HDL-cholesterol	homozygote		decreased circulating HDL cholesterol level	7.925644496253881E-8
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	7.960113634908339E-8
Prkdc Prkdcem2(IMPC)Ics	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	8.107191717954265E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Eye Morphology	Right corneal thickness	homozygote		increased cornea thickness	8.205006452044472E-8
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Eye Morphology	Corneal mineralization	heterozygote		abnormal cornea morphology	8.267865325706225E-8
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Left vitreous humour thickness	homozygote		abnormal vitreous body morphology	8.284136754355131E-8
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	8.345832469558445E-8
Sun1 Sun1tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI1	homozygote		decreased prepulse inhibition	8.470034629226575E-8
Capn10 Capn10tm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	8.571471710183687E-8
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	8.682250296487837E-8
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	8.691230846125109E-8
Nxn Nxntm1b(EUCOMM)Wtsi	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	8.737162460192849E-8
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	8.751996460887312E-8
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	8.83823432218378E-8
Med25 Med25tm1b(KOMP)Wtsi	X-ray	Tibia length	heterozygote		short tibia	8.919414540287107E-8
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	9.107942133823599E-8
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	9.136584822044824E-8
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair distribution - back	homozygote		abnormal coat/ hair morphology	9.208552143036286E-8
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		hyperactivity	9.249124133248188E-8
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Hematology	Hematocrit	homozygote		decreased hematocrit	9.405405165807679E-8
Rnf10 Rnf10tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	9.438399217742699E-8
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	9.71577875930052E-8
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	BMC/Body weight	heterozygote		decreased bone mineral content	9.735970252222614E-8
Cbl Cbltm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	PR	heterozygote		prolonged PR interval	9.853454230324132E-8
Fut4 Fut4em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Lean mass	homozygote		decreased lean body mass	1.0306480646704586E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	CD8 CD44+CD62L+ T cells	homozygote		increased effector memory CD8-positive, alpha-beta T cell number	1.0417213047730911E-7
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Bone Mineral Density (excluding skull)	heterozygote		increased bone mineral density	1.0507628189770912E-7
Phf8 Phf8tm1dIcs	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	1.0619596224614725E-7
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu	Eye Morphology	Left anterior chamber depth	heterozygote		abnormal eye anterior chamber depth	1.0750337509080055E-7
Rnf10 Rnf10tm1b(KOMP)Wtsi	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	1.0871663391753827E-7
Ptpra Ptpratm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		increased startle reflex	1.1447450276591553E-7
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	1.1617892425874743E-7
Ptafr Ptafrtm1b(KOMP)Wtsi	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.1709369829304705E-7
Gm12258 Gm12258tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.1734820759556897E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	Total protein	homozygote		decreased circulating total protein level	1.2403192783949635E-7
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	X-ray	Tibia length	heterozygote		short tibia	1.3263048970202362E-7
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.3438665291687357E-7
Parp1 Parp1tm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	1.3872666215775098E-7
Prrt2 Prrt2tm1b(KOMP)Wtsi	Fear Conditioning	% Cue freezing total	homozygote		abnormal cued conditioning behavior	1.3970135626095725E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	1.4291900640728272E-7
Epx Epxtm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat mass	homozygote		increased total body fat amount	1.4968411221616407E-7
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	1.5024957633613667E-7
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	1.5117379348339455E-7
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) count	homozygote		increased large unstained cell number	1.5447241707988724E-7
Dnm1l Dnm1ltm1b(KOMP)Wtsi	Eye Morphology	Vitreous	heterozygote		abnormal vitreous body morphology	1.5494228478019068E-7
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	1.5735480474177166E-7
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Eye Morphology	Persistence of hyaloid vascular system	heterozygote		persistence of hyaloid vascular system	1.5794763896792574E-7
Thra Thratm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Body length	heterozygote		decreased body length	1.585747497756529E-7
Parp1 Parp1tm1b(EUCOMM)Hmgu	Immunophenotyping	NK Cells (panel B)	homozygote		decreased NK cell number	1.626418111300154E-7
Smc5 Smc5tm1b(KOMP)Wtsi	Clinical Chemistry	HDL-cholesterol	heterozygote		decreased circulating HDL cholesterol level	1.674753775660065E-7
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	1.687702706476557E-7
Pdpr Pdprtm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) differential count	homozygote		decreased large unstained cell number	1.6935425151132222E-7
Epx Epxtm1b(EUCOMM)Wtsi	Clinical Chemistry	Triglycerides	homozygote		increased circulating triglyceride level	1.756281591269726E-7
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Fear Conditioning	% Cue freezing total	homozygote		abnormal cued conditioning behavior	1.7988890022024862E-7
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair distribution - head	homozygote		abnormal coat/ hair morphology	1.807482590265863E-7
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - abdomen	homozygote		abnormal coat appearance	1.807482590265863E-7
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - back	homozygote		abnormal coat appearance	1.807482590265863E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair distribution - head	homozygote		abnormal coat/ hair morphology	1.8350654329424287E-7
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	1.893416055054331E-7
Obp2a Obp2atm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - back	homozygote		abnormal coat/hair pigmentation	2.032969632637105E-7
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		decreased circulating alkaline phosphatase level	2.055095507103033E-7
Setx Setxtm1b(EUCOMM)Wtsi	Immunophenotyping	Eosinophils	homozygote		increased eosinophil cell number	2.086218842123344E-7
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	2.1423811347176525E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	2.1701970354115474E-7
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	2.223028872094801E-7
Il10ra Il10ratm1b(KOMP)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	2.2695599000144284E-7
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	White blood cell count	homozygote		increased leukocyte cell number	2.3226920120578143E-7
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	T Cells (panel B)	heterozygote		increased T cell number	2.3432983198290458E-7
Pdpr Pdprtm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) differential count	homozygote		decreased large unstained cell number	2.3436034268797812E-7
Iqce Iqcetm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	2.391167015503015E-7
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	homozygote		increased lymphocyte cell number	2.3933185389068967E-7
Dnm1l Dnm1ltm1b(KOMP)Wtsi	Eye Morphology	Persistence of hyaloid vascular system	heterozygote		persistence of hyaloid vascular system	2.3983588448572846E-7
Rnf10 Rnf10tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	2.461762278471724E-7
Exd1 Exd1tm1b(EUCOMM)Hmgu	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	2.5062740860448685E-7
Laptm4a Laptm4atm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	2.5334870201731974E-7
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	2.5478374254817027E-7
Bmp10 Bmp10tm3b(EUCOMM)Hmgu	Clinical Chemistry	Creatinine	heterozygote		decreased circulating creatinine level	2.552330613525555E-7
Casq1 Casq1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Creatinine	homozygote		decreased circulating creatinine level	2.5772172307370056E-7
Nab2 Nab2tm1b(EUCOMM)Hmgu	Clinical Chemistry	HDL-cholesterol	homozygote		decreased circulating HDL cholesterol level	2.6362226890341844E-7
Capn10 Capn10tm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	2.6681863118938054E-7
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	X-ray	Tibia length	heterozygote		short tibia	2.682641877527203E-7
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Body length	heterozygote		decreased body length	2.685910942545888E-7
Bmp10 Bmp10tm3b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Locomotor activity	heterozygote		decreased exploration in new environment	2.6874835157286725E-7
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	2.7285915393804316E-7
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Open Field	Periphery average speed	homozygote		hyperactivity	2.837654164977721E-7
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Eye Morphology	Retinal Blood Vessels	heterozygote		abnormal retina vasculature morphology	2.845895608061255E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Locomotor activity	homozygote		decreased exploration in new environment	2.8992093348279013E-7
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Gait	homozygote		abnormal gait	2.899951994095318E-7
App Apptm1b(KOMP)Wtsi	Eye Morphology	Right corneal thickness	heterozygote		increased cornea thickness	2.9222300668152457E-7
Otub1 Otub1tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	2.9598660944429867E-7
Tubg1 Tubg1tm1dIcs	Open Field	Center resting time	heterozygote		decreased locomotor activity	2.9703807058467646E-7
Capn10 Capn10tm1b(EUCOMM)Wtsi	Open Field	Center average speed	homozygote		hyperactivity	3.0245709581322444E-7
Cstb Cstbtm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	3.0399692718674487E-7
Cstb Cstbtm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	3.091325879722717E-7
Nab2 Nab2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	3.096585885487002E-7
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	3.12577384420365E-7
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Eye Morphology	Persistence of hyaloid vascular system	homozygote		persistence of hyaloid vascular system	3.192790813955071E-7
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		decreased startle reflex	3.2485627343703527E-7
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Periphery distance travelled	homozygote		hyperactivity	3.313154763873172E-7
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	3.3151400202768855E-7
Coq6 Coq6tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	heterozygote		increased fasting circulating glucose level	3.556855006081605E-7
Il2ra Il2ratm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	3.574930929062248E-7
Trpm6 Trpm6tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Body length	heterozygote		increased body length	3.6249022627998784E-7
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Fat/Body weight	heterozygote		decreased total body fat amount	3.650161204404867E-7
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Whole arena average speed	hemizygote		hyperactivity	3.669634054404014E-7
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	3.6884520682178845E-7
Prkdc Prkdcem2(IMPC)Ics	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	3.7087878013153386E-7
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Periphery distance travelled	hemizygote		hyperactivity	3.764818075069343E-7
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Open Field	Number of center entries	heterozygote		hyperactivity	3.784347200053162E-7
Rnf144b Rnf144btm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	3.796421026436292E-7
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Periphery distance travelled	homozygote		decreased locomotor activity	3.8338293961714953E-7
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	4.109633664484136E-7
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	4.175863637101429E-7
Sun1 Sun1tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	4.2286822576897976E-7
Il2ra Il2ratm1b(EUCOMM)Wtsi	Fear Conditioning	% Pre-cue freezing total	homozygote		abnormal freezing behavior	4.274642435575515E-7
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	T Cells (panel B)	heterozygote		increased T cell number	4.2769386254803976E-7
Fut4 Fut4em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		increased total body fat amount	4.3324050125193025E-7
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Indirect Calorimetry	Total food intake	homozygote		increased food intake	4.404495541621145E-7
Lcp2 Lcp2tm1b(KOMP)Wtsi	Eye Morphology	Lens Opacity	heterozygote		cataract	4.408056213378586E-7
Lcp2 Lcp2tm1b(KOMP)Wtsi	Eye Morphology	Lens	heterozygote		abnormal lens morphology	4.408056213378586E-7
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Body length	homozygote		increased body length	4.4484690420176776E-7
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	4.629335705885751E-7
Rwdd3 Rwdd3tm1b(KOMP)Wtsi	Grip Strength	Forelimb grip strength measurement mean	heterozygote		decreased grip strength	4.650638061320933E-7
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Echo	Fractional Shortening	homozygote		increased cardiac muscle contractility	4.747177797526092E-7
Pdpr Pdprtm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	4.776709374709753E-7
Lat Latem1(IMPC)Ics	Eye Morphology	Right vitreous humor thickness	homozygote		abnormal vitreous body morphology	4.826097210752778E-7
Kif5c Kif5ctm1dIcs	Hematology	Eosinophil differential count	heterozygote		increased eosinophil cell number	4.923365395370638E-7
Arhgap24 Arhgap24tm1b(KOMP)Wtsi	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	4.950533707415161E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	4.977247272108798E-7
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Clinical Chemistry	Creatinine	homozygote		increased circulating creatinine level	4.994636810806696E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - abdomen	homozygote		abnormal coat appearance	5.120124342283816E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - abdomen	homozygote		abnormal coat/hair pigmentation	5.120124342283816E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - back	homozygote		abnormal coat/hair pigmentation	5.120124342283816E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - back	homozygote		abnormal coat appearance	5.120124342283816E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - abdomen	homozygote		abnormal coat/hair pigmentation	5.120124342283816E-7
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Heart Weight	Tibia length	homozygote		short tibia	5.125520488036273E-7
Mapt Mapttm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	5.144844976712193E-7
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Combined SHIRPA and Dysmorphology	Locomotor activity	hemizygote		increased exploration in new environment	5.148951913724886E-7
Aak1 Aak1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	5.186992098060728E-7
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Hematology	Eosinophil differential count	homozygote		increased eosinophil cell number	5.195267362978484E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - back	homozygote		abnormal coat/hair pigmentation	5.208298716752324E-7
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		hyperactivity	5.231919431025744E-7
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Right corneal thickness	homozygote		decreased cornea thickness	5.275433636597882E-7
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Eye Morphology	Vitreous	heterozygote		abnormal vitreous body morphology	5.306943080540805E-7
App Apptm1b(KOMP)Wtsi	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	heterozygote		increased blood urea nitrogen level	5.405852903095365E-7
Parp1 Parp1tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	5.538700520446582E-7
Bahd1 Bahd1tm2b(KOMP)Wtsi	Eye Morphology	Retina (combined)	heterozygote		abnormal retina morphology	5.599360974883894E-7
Elk3 Elk3em1(IMPC)Ics	Clinical Chemistry	Total cholesterol	heterozygote		increased circulating cholesterol level	5.611472602140566E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.69224880564434E-7
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	5.697789902114891E-7
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	5.811605774397322E-7
Sun1 Sun1tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.882051823391521E-7
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Periphery distance travelled	heterozygote		hyperactivity	5.914410508012224E-7
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	5.999696668368415E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Open Field	Whole arena resting time	homozygote		decreased locomotor activity	6.064610147404892E-7
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Startle response	homozygote		abnormal startle reflex	6.271795882639708E-7
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	6.313322273854283E-7
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	X-ray	Digit integrity	homozygote		abnormal digit morphology	6.39698441773362E-7
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Activity (body position)	homozygote		abnormal locomotor behavior	6.720496799061948E-7
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		short tibia	6.738858360222366E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Open Field	Distance travelled - total	homozygote		decreased locomotor activity	6.766816227354866E-7
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	7.01588248830376E-7
Taf2 Taf2tm1b(EUCOMM)Hmgu	Open Field	Center resting time	heterozygote		hyperactivity	7.102210588527669E-7
Elk3 Elk3em1(IMPC)Ics	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	7.179959311542916E-7
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		decreased circulating total protein level	7.202187362054246E-7
Capn10 Capn10tm1b(EUCOMM)Wtsi	Clinical Chemistry	Cholesterol ratio	homozygote		abnormal cholesterol homeostasis	7.203021255008935E-7
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	7.376144708359789E-7
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Tremor	homozygote		tremors	7.401316111099732E-7
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	7.475833285752742E-7
Ino80 Ino80tm1a(EUCOMM)Hmgu	Open Field	Center average speed	heterozygote		decreased locomotor activity	7.54309041894885E-7
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) differential count	heterozygote		decreased large unstained cell number	7.550042369075527E-7
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	7.572434128633176E-7
Bahd1 Bahd1tm2b(KOMP)Wtsi	Hematology	Lymphocyte cell count	heterozygote		decreased lymphocyte cell number	7.636984378223133E-7
Spn Spnem1(IMPC)Ics	Eye Morphology	Right corneal thickness	homozygote		increased cornea thickness	7.721131964899541E-7
Nxn Nxntm1b(EUCOMM)Wtsi	X-ray	Digit integrity	heterozygote		abnormal digit morphology	7.982161491781881E-7
Iqce Iqcetm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Activity (body position)	homozygote		abnormal locomotor behavior	8.002277809282532E-7
Sun1 Sun1tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	8.03565967544273E-7
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	8.333628898071765E-7
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	X-ray	Tibia length	heterozygote		short tibia	8.414430112679838E-7
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Lean mass	heterozygote		increased lean body mass	8.472858894492674E-7
Casq1 Casq1tm1b(EUCOMM)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	8.61330704537977E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Open Field	Periphery resting time	homozygote		decreased locomotor activity	8.691341122357699E-7
Lat Latem1(IMPC)Ics	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	8.917079412640305E-7
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - head	homozygote		abnormal coat appearance	8.943517855186656E-7
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair distribution - back	homozygote		abnormal coat/ hair morphology	8.943517855186656E-7
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) differential count	heterozygote		decreased large unstained cell number	9.046194122674933E-7
Prkab1 Prkab1tm1b(KOMP)Wtsi	Hematology	Hemoglobin	homozygote		decreased hemoglobin content	9.378043159813387E-7
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat mass	heterozygote		decreased total body fat amount	9.437638937015436E-7
Dnal4 Dnal4tm1b(EUCOMM)Wtsi	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	9.603629678167636E-7
Cstb Cstbtm1b(EUCOMM)Wtsi	Open Field	Number of rears - total	homozygote		increased vertical activity	9.608367008695495E-7
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	9.660573141445639E-7
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	gd T cells	homozygote		immune system phenotype	9.677695516074891E-7
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	9.932502962328726E-7
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Hematology	Hematocrit	homozygote		increased hematocrit	9.952468644769397E-7
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	1.0176295290875714E-6
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) differential count	homozygote		increased large unstained cell number	1.0328834605388693E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	1.0336755167372758E-6
Dcp2 Dcp2tm1b(KOMP)Wtsi	Heart Weight	Heart weight	heterozygote		increased heart weight	1.065686433321389E-6
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Eye Morphology	Retinal Blood Vessels Pattern	heterozygote		abnormal retina blood vessel morphology	1.069949462362274E-6
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	1.073990006261738E-6
Cx3cl1 Cx3cl1em3(IMPC)Ics	Combined SHIRPA and Dysmorphology	Locomotor activity	homozygote		decreased exploration in new environment	1.0777854413390742E-6
Smc5 Smc5tm1b(KOMP)Wtsi	Clinical Chemistry	Total cholesterol	heterozygote		decreased circulating cholesterol level	1.0944671657853178E-6
Ptafr Ptafrtm1b(KOMP)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.1277335261183907E-6
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total protein	heterozygote		increased circulating total protein level	1.1437239209044492E-6
Tti2 Tti2tm1b(KOMP)Wtsi	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	1.187523707812943E-6
Tmem50b Tmem50btm1b(EUCOMM)Wtsi	Eye Morphology	Right vitreous humor thickness	homozygote		abnormal vitreous body morphology	1.1888519111380447E-6
Med25 Med25tm1b(KOMP)Wtsi	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	1.1916253015442635E-6
Dbnl Dbnltm1b(KOMP)Wtsi	Indirect Calorimetry	Total water intake	homozygote		increased fluid intake	1.2325664329182473E-6
Ino80 Ino80tm1a(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Locomotor activity	heterozygote		decreased exploration in new environment	1.2493011354308692E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	X-ray	Digit integrity	homozygote		abnormal digit morphology	1.276476950806682E-6
Bnc2 Bnc2tm1b(KOMP)Wtsi	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	1.2781785017068614E-6
Mapt Mapttm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	1.2947266441187821E-6
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	hemizygote		abnormal auditory brainstem response	1.3014692967772135E-6
Dyrk2 Dyrk2em1(IMPC)Ics	Hematology	Large Unstained Cell (LUC) differential count	heterozygote		decreased large unstained cell number	1.3083896419630037E-6
Casq1 Casq1tm1b(EUCOMM)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	1.3150927316019079E-6
Tmem50b Tmem50btm1b(EUCOMM)Wtsi	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	1.317814962931152E-6
Nxn Nxntm1b(EUCOMM)Wtsi	Open Field	Periphery distance travelled	heterozygote		decreased locomotor activity	1.318218437518226E-6
Stradb Stradbtm1b(KOMP)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	1.3284976603245013E-6
Hmgn1 Hmgn1em1(IMPC)Ics	Indirect Calorimetry	Total food intake	homozygote		decreased food intake	1.3710453004023293E-6
Laptm4a Laptm4atm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	ST	homozygote		prolonged ST segment	1.3727531040785834E-6
Gm12258 Gm12258tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		increased startle reflex	1.3758241266259574E-6
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Cholesterol ratio	homozygote		abnormal cholesterol homeostasis	1.402817474627227E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair distribution - head	homozygote		abnormal coat/ hair morphology	1.4188551631377777E-6
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	X-ray	Tibia length	heterozygote		short tibia	1.4487725366052473E-6
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	1.4553442042597453E-6
Taf2 Taf2tm1b(EUCOMM)Hmgu	Clinical Chemistry	HDL-cholesterol	heterozygote		increased circulating HDL cholesterol level	1.4868127209410886E-6
Arhgap24 Arhgap24tm1b(KOMP)Wtsi	Echo	LVAWd	homozygote		increased heart left ventricle size	1.4876683280817815E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	1.5139245306272642E-6
Dpp4 Dpp4tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.5198659184534336E-6
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	heterozygote		decreased prepulse inhibition	1.5452504840141046E-6
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	1.6165367924259044E-6
Il2ra Il2ratm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Bone Mineral Density (excluding skull)	homozygote		decreased bone mineral density	1.6165630540854181E-6
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total cholesterol	heterozygote		increased circulating cholesterol level	1.6190562064366532E-6
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	DN NKT cells	heterozygote		increased CD4-negative NK T cell number	1.6260189568129135E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI1	homozygote		decreased prepulse inhibition	1.6516416962986114E-6
Sun1 Sun1tm1b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	homozygote		increased lymphocyte cell number	1.6843788444020902E-6
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Periphery average speed	homozygote		hyperactivity	1.7286522506765323E-6
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	1.7442625903640874E-6
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	heterozygote		short tibia	1.804004000405257E-6
Smc5 Smc5tm1b(KOMP)Wtsi	Clinical Chemistry	Total bilirubin	heterozygote		increased circulating bilirubin level	1.8252621885039844E-6
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	1.826915877245483E-6
Dusp11 Dusp11tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Activity (body position)	homozygote		abnormal locomotor behavior	1.8300906958756968E-6
Sun1 Sun1tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Lean mass	homozygote		decreased lean body mass	1.8631778857525205E-6
Hrh4 Hrh4tm1b(EUCOMM)Hmgu	Eye Morphology	Right corneal thickness	homozygote		increased cornea thickness	1.875514499261044E-6
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Body length	heterozygote		decreased body length	1.8840262328012614E-6
Ino80 Ino80tm1a(EUCOMM)Hmgu	Open Field	Distance travelled - total	heterozygote		decreased locomotor activity	1.9044662167289061E-6
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		decreased circulating total protein level	1.9046016177526326E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Hindlimb digit - shape	homozygote		abnormal digit morphology	1.919323949550744E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Forelimb digit - size	homozygote		abnormal digit morphology	1.919323949550744E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Forelimb nail - length	homozygote		abnormal nail morphology	1.919323949550744E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Hindlimb digit - size	homozygote		abnormal digit morphology	1.919323949550744E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Forelimb digit - shape	homozygote		abnormal digit morphology	1.919323949550744E-6
Iah1 Iah1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		decreased circulating alkaline phosphatase level	1.9391993646422634E-6
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	1.9575520582293393E-6
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	1.9733511180675123E-6
Smc5 Smc5tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Tremor	heterozygote		tremors	1.9958692973887082E-6
Rspo1 Rspo1tm2b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Lean mass	homozygote		decreased lean body mass	1.9973217604274396E-6
Med25 Med25tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	2.016467306020786E-6
Scaper Scapertm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	2.0174309156573145E-6
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	2.018432041950291E-6
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	heterozygote		increased fasting circulating glucose level	2.0242828213667963E-6
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Tail - morphology	homozygote		abnormal tail morphology	2.0391914858919336E-6
Ttc39a Ttc39atm1b(KOMP)Mbp	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	2.0449426756385947E-6
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	2.055716095128446E-6
Dbnl Dbnltm1b(KOMP)Wtsi	Heart Weight	Heart weight	homozygote		increased heart weight	2.070240498142084E-6
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Optic Disc	homozygote		abnormal optic disk morphology	2.0753368517034687E-6
Parp1 Parp1tm1b(EUCOMM)Hmgu	Immunophenotyping	CD8 CD44+CD62L+ T cells	homozygote		increased effector memory CD8-positive, alpha-beta T cell number	2.0760671759489924E-6
Ackr3 Ackr3tm2b(EUCOMM)Wtsi	Grip Strength	Forelimb grip strength measurement mean	heterozygote		decreased grip strength	2.086372887788457E-6
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	2.1135977021913277E-6
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Left outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	2.1140306216693716E-6
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) differential count	heterozygote		increased large unstained cell number	2.1268369891913608E-6
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	DN NKT cells	heterozygote		increased CD4-negative NK T cell number	2.140382093784865E-6
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi	Eye Morphology	Right vitreous humor thickness	homozygote		abnormal vitreous body morphology	2.1755863599537406E-6
Spn Spnem1(IMPC)Ics	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		increased total body fat amount	2.180137244067737E-6
Casq1 Casq1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	2.188335429309518E-6
Thra Thratm1b(EUCOMM)Wtsi	Eye Morphology	Left inner nuclear layer	heterozygote		abnormal retina inner nuclear layer morphology	2.189220367654343E-6
Smc5 Smc5tm1b(KOMP)Wtsi	Hematology	Eosinophil cell count	heterozygote		increased eosinophil cell number	2.293515308338101E-6
Dbnl Dbnltm1b(KOMP)Wtsi	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	2.356562390559702E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	2.381013473495841E-6
Pdpr Pdprtm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	2.3892334866104648E-6
Casq1 Casq1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Cholesterol ratio	homozygote		abnormal cholesterol homeostasis	2.4033263343881117E-6
Ncs1 Ncs1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	2.416763663859456E-6
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	ST	heterozygote		prolonged ST segment	2.4520377337466925E-6
Morc3 Morc3tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	2.4553603452659445E-6
Fut4 Fut4em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Fat mass	homozygote		increased total body fat amount	2.4900118660298176E-6
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Number of rears - total	homozygote		decreased vertical activity	2.4981864044093527E-6
Gemin4 Gemin4em1(IMPC)Ics	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	2.523494913475588E-6
Rnf10 Rnf10tm1b(KOMP)Wtsi	Open Field	Number of rears - total	homozygote		increased vertical activity	2.5394272142875707E-6
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi	Hematology	Eosinophil differential count	homozygote		increased eosinophil cell number	2.589377800177317E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Head morphology	homozygote		abnormal head morphology	2.6015634375653462E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	NK Subsets (Q4)	homozygote		increased Ly6C-positive mature NK cell number	2.609350531201926E-6
Il2ra Il2ratm1b(EUCOMM)Wtsi	Electrocardiogram (ECG)	PR	homozygote		prolonged PR interval	2.6125594558834564E-6
Fut4 Fut4em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		decreased lean body mass	2.6334039375797147E-6
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Center distance travelled	homozygote		hyperactivity	2.6556056127446936E-6
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	2.7609373773884727E-6
Cav1 Cav1em2(IMPC)Ics	Hematology	Hemoglobin	homozygote		increased hemoglobin content	2.79375194622844E-6
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) count	homozygote		increased large unstained cell number	2.7947673970629694E-6
Saxo1 Saxo1tm1b(EUCOMM)Hmgu	Open Field	Periphery average speed	homozygote		hyperactivity	2.8198905965837184E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	2.8232225304236636E-6
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Basophil cell count	homozygote		increased basophil cell number	2.833442067640135E-6
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	2.8400033897924004E-6
Lmna Lmnatm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	heterozygote		improved glucose tolerance	2.8460960947995773E-6
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QRS	heterozygote		prolonged QRS complex duration	2.913172011176357E-6
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Aggression	homozygote		increased aggression	2.9847378755221143E-6
Spn Spnem1(IMPC)Ics	X-ray	Tibia length	homozygote		long tibia	2.9977345548104495E-6
Aak1 Aak1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI1	homozygote		increased prepulse inhibition	3.0412084015551955E-6
Med25 Med25tm1b(KOMP)Wtsi	Rotarod	Latency to fall mean	heterozygote		abnormal motor capabilities/coordination/movement	3.0495541523123393E-6
Il2ra Il2ratm1b(EUCOMM)Wtsi	Heart Weight	Heart weight	homozygote		decreased heart weight	3.0719959340785863E-6
Pax4 Pax4tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Tremor	heterozygote		tremors	3.135042788926512E-6
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	3.1744807529321406E-6
Rnf144b Rnf144btm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Vocalization	homozygote		abnormal vocalization	3.233821644244017E-6
Phf8 Phf8tm1dIcs	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	3.2458708574267803E-6
Nae1 Nae1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Phosphorus	heterozygote		increased circulating phosphate level	3.2609821118967375E-6
Sun1 Sun1tm1b(EUCOMM)Wtsi	Open Field	Center resting time	homozygote		decreased locomotor activity	3.2775913041405147E-6
Cbl Cbltm1b(EUCOMM)Hmgu	Echo	LVPWd	heterozygote		thick ventricular wall	3.2887414818105754E-6
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Eye Morphology	Left inner nuclear layer	homozygote		abnormal retina inner nuclear layer morphology	3.2906064006965607E-6
Thra Thratm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Limb grasp	heterozygote		limb grasping	3.3002932013914688E-6
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Open Field	Whole arena average speed	homozygote		decreased locomotor activity	3.346690618855064E-6
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	X-ray	Tibia length	heterozygote		short tibia	3.3707149214023957E-6
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Combined SHIRPA and Dysmorphology	Aggression	hemizygote		increased aggression	3.3822971090557985E-6
Ddr1 Ddr1tm1b(EUCOMM)Hmgu	Open Field	Center average speed	heterozygote		hyperactivity	3.4390732253086753E-6
Cx3cl1 Cx3cl1em3(IMPC)Ics	Open Field	Whole arena average speed	homozygote		decreased locomotor activity	3.4431552649039077E-6
Lat Latem1(IMPC)Ics	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	3.478250164334895E-6
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Tremor	homozygote		tremors	3.5466964618535712E-6
Iqce Iqcetm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	3.565210136002861E-6
Lca5l Lca5lem1(IMPC)Ics	Hematology	Platelet count	homozygote		thrombocytopenia	3.6020896914124023E-6
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total protein	homozygote		decreased circulating total protein level	3.6182730127620744E-6
Ncam2 Ncam2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Locomotor activity	homozygote		decreased exploration in new environment	3.6406968320079613E-6
Prkdc Prkdcem2(IMPC)Ics	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	3.7090342175361E-6
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Hematology	Hemoglobin	heterozygote		decreased hemoglobin content	3.709297743625939E-6
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Aspartate aminotransferase	homozygote		increased circulating aspartate transaminase level	3.7093723221914843E-6
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	3.7547827105299802E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	3.8142657103890087E-6
Satb1 Satb1tm1b(EUCOMM)Hmgu	Eye Morphology	Vitreous	heterozygote		abnormal vitreous body morphology	3.814830961346161E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	CD8 T cells	homozygote		decreased CD8-positive, alpha-beta T cell number	3.883155386574799E-6
Il10ra Il10ratm1b(KOMP)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	homozygote		improved glucose tolerance	3.89331808037241E-6
Ino80 Ino80tm1a(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Aggression	heterozygote		increased aggression	3.900528099620715E-6
Sun1 Sun1tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	3.901811396644916E-6
Cstb Cstbtm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	3.901811396644916E-6
Arhgap24 Arhgap24tm1b(KOMP)Wtsi	Echo	LVAWd	homozygote		increased heart left ventricle size	3.92667789128609E-6
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration context-1	homozygote		abnormal contextual conditioning behavior	4.024737336294493E-6
Cd19 Cd19em2(IMPC)Ics	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	4.110589543415699E-6
Saxo1 Saxo1tm1b(EUCOMM)Hmgu	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	4.13208408645005E-6
Septin3 Septin3tm1b(KOMP)Wtsi	Clinical Chemistry	Phosphorus	heterozygote		decreased circulating phosphate level	4.134958089707652E-6
Coq6 Coq6tm1b(EUCOMM)Hmgu	Eye Morphology	Persistence of hyaloid vascular system	heterozygote		persistence of hyaloid vascular system	4.1767598304431885E-6
Dgkk Dgkkem1(IMPC)Ics	Grip Strength	Forelimb grip strength normalised against body weight	hemizygote		decreased grip strength	4.1984926610894036E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	NK cells (panel A)	homozygote		decreased NK cell number	4.239067948219599E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	homozygote		decreased prepulse inhibition	4.303282821638277E-6
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Hemoglobin	heterozygote		decreased hemoglobin content	4.3586173887888435E-6
Rwdd3 Rwdd3tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		decreased grip strength	4.364622327557299E-6
Laptm4a Laptm4atm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	4.3962031668343116E-6
Dpp4 Dpp4tm1b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	homozygote		decreased lymphocyte cell number	4.408296717883786E-6
Bahd1 Bahd1tm2b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		increased startle reflex	4.458388048078632E-6
Myo18b Myo18bem2(IMPC)Ics	Clinical Chemistry	Triglycerides	heterozygote		increased circulating triglyceride level	4.572536454361398E-6
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Right outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	4.578718744596699E-6
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	4.5982719711901154E-6
Rnf10 Rnf10tm1b(KOMP)Wtsi	Open Field	Center distance travelled	homozygote		decreased locomotor activity	4.711928340839222E-6
Fut4 Fut4em1(IMPC)Ics	Body Composition (DEXA lean/fat)	BMC/Body weight	homozygote		increased bone mineral content	4.800440819963114E-6
Iqce Iqcetm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Tremor	homozygote		tremors	4.8187362153839786E-6
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Combined SHIRPA and Dysmorphology	Vocalization	hemizygote		abnormal vocalization	4.840011115447851E-6
Aak1 Aak1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	4.910171355732018E-6
Il10ra Il10ratm1b(KOMP)Wtsi	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	4.92008348373929E-6
Lca5l Lca5lem1(IMPC)Ics	Hematology	Platelet count	homozygote		thrombocytopenia	4.92793196826824E-6
Thra Thratm1b(EUCOMM)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		decreased grip strength	5.014490398025373E-6
Dgkk Dgkkem1(IMPC)Ics	Clinical Chemistry	Total cholesterol	hemizygote		increased circulating cholesterol level	5.020877324568573E-6
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	5.056197096564574E-6
Rrp1b Rrp1btm2b(EUCOMM)Hmgu	Eye Morphology	Vitreous	homozygote		abnormal vitreous body morphology	5.082010829937644E-6
Ncam2 Ncam2tm1b(EUCOMM)Hmgu	Hematology	Eosinophil cell count	homozygote		increased eosinophil cell number	5.173280896997312E-6
Rnf10 Rnf10tm1b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	5.203052751312498E-6
Sun1 Sun1tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat mass	homozygote		increased total body fat amount	5.240900009084726E-6
Stat1 Stat1tm2b(EUCOMM)Wtsi	Clinical Chemistry	Alkaline phosphatase	homozygote		decreased circulating alkaline phosphatase level	5.249355126579758E-6
Kctd15 Kctd15tm1b(EUCOMM)Wtsi	Clinical Chemistry	Creatinine	heterozygote		increased circulating creatinine level	5.353321284928825E-6
Saxo1 Saxo1tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		hyperactivity	5.396801043389132E-6
Setx Setxtm1b(EUCOMM)Wtsi	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	5.4886177167645656E-6
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Lean mass	homozygote		decreased lean body mass	5.685685664502671E-6
Pdlim4 Pdlim4em1(IMPC)Ics	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	5.693322691513458E-6
Otub1 Otub1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Mineral Content (excluding skull)	heterozygote		decreased bone mineral content	5.734601018048124E-6
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	5.780190349469194E-6
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	5.8448067647987045E-6
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	5.863165370101342E-6
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi	Fear Conditioning	% Context freezing total	heterozygote		abnormal contextual conditioning behavior	5.883209269086365E-6
Clec9a Clec9atm1b(KOMP)Wtsi	Echo	Fractional Shortening	homozygote		decreased cardiac muscle contractility	5.897134087717859E-6
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu	Open Field	Center resting time	homozygote		hyperactivity	5.916313511988847E-6
Atad2b Atad2btm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration context-2	homozygote		abnormal contextual conditioning behavior	6.004003353154985E-6
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi	Fear Conditioning	Context freezing total	heterozygote		abnormal contextual conditioning behavior	6.007631782267708E-6
Dpp4 Dpp4tm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	6.073160875530448E-6
Nlk Nlktm2b(KOMP)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	6.087720976211131E-6
Prrt2 Prrt2tm1b(KOMP)Wtsi	X-ray	Tibia length	homozygote		short tibia	6.146346095192712E-6
Setx Setxtm1b(EUCOMM)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	6.230770395632135E-6
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		decreased circulating calcium level	6.2463077483698726E-6
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	6.2600665842182934E-6
Enpp4 Enpp4em1(IMPC)Ics	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	6.268675406317925E-6
Gpr108 Gpr108tm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	6.382630544976564E-6
Tgif2 Tgif2tm1b(EUCOMM)Wtsi	Clinical Chemistry	Calcium	heterozygote		decreased circulating calcium level	6.4405821831314825E-6
Cdk8 Cdk8tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	6.483353445219109E-6
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	heterozygote		increased prepulse inhibition	6.521358955069445E-6
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Lean/Body weight	heterozygote		increased lean body mass	6.642541393375723E-6
Trpm6 Trpm6tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		increased grip strength	6.654313438048121E-6
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	DN CD44+CD62L- NKT cells	heterozygote		increased memory-marker CD4-negative NK T cell number	6.657599897152977E-6
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Percentage center time	homozygote		abnormal behavior	6.684907020826358E-6
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Center permanence time	homozygote		increased thigmotaxis	6.684907020826358E-6
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Periphery permanence time	homozygote		increased thigmotaxis	6.704263341816841E-6
Gp6 Gp6tm2b(EUCOMM)Hmgu	Hematology	Lymphocyte cell count	homozygote		increased lymphocyte cell number	6.713715265505016E-6
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	6.719562406942714E-6
Ncam2 Ncam2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	6.728859716531588E-6
Mtmr12 Mtmr12tm1b(KOMP)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	6.810686500102747E-6
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Eye Morphology	Right inner nuclear layer	homozygote		abnormal retina inner nuclear layer morphology	6.823608146078186E-6
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Hematology	Hemoglobin	homozygote		increased hemoglobin content	6.843039955128916E-6
Klf12 Klf12tm1b(EUCOMM)Wtsi	Eye Morphology	Right corneal thickness	heterozygote		increased cornea thickness	6.8793683567491826E-6
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	7.083445780153852E-6
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	7.3386427175137214E-6
Il10ra Il10ratm1b(KOMP)Wtsi	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	7.431784524669638E-6
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Center distance travelled	homozygote		decreased locomotor activity	7.436898613377707E-6
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	7.502151220251108E-6
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - head	homozygote		abnormal coat appearance	7.624357294844231E-6
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - abdomen	homozygote		abnormal coat appearance	7.624357294844231E-6
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair distribution - head	homozygote		abnormal coat/ hair morphology	7.624357294844231E-6
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair texture / appearance - back	homozygote		abnormal coat appearance	7.624357294844231E-6
Dbn1 Dbn1tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		decreased grip strength	7.720507710473612E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	7.721248948655557E-6
Parp1 Parp1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI1	homozygote		increased prepulse inhibition	7.751234079478309E-6
Exd1 Exd1tm1b(EUCOMM)Hmgu	Heart Weight	Heart weight	homozygote		increased heart weight	7.81233211455401E-6
Nfatc2ip Nfatc2ipem1(IMPC)Ics	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	7.85985048423754E-6
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	7.877544703660533E-6
Thra Thratm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	heterozygote		improved glucose tolerance	7.931711479614023E-6
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Clinical Chemistry	HDL-cholesterol	homozygote		increased circulating HDL cholesterol level	8.147690095938742E-6
Med25 Med25tm1b(KOMP)Wtsi	Hematology	Mean cell volume	heterozygote		decreased mean corpuscular volume	8.171374247467611E-6
Spn Spnem1(IMPC)Ics	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	8.203556717489846E-6
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Eye Morphology	Retina (combined)	homozygote		abnormal retina morphology	8.27880921860924E-6
Timm50 Timm50tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	heterozygote		decreased total body fat amount	8.465241080557462E-6
Atad2b Atad2btm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	8.49367006594548E-6
Ect2 Ect2tm1b(EUCOMM)Wtsi	Grip Strength	Forelimb grip strength measurement mean	heterozygote		decreased grip strength	8.630963748146314E-6
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	8.739164513826836E-6
Dync1h1 Dync1h1tm1dIcs	Open Field	Center resting time	heterozygote		decreased locomotor activity	8.7973194240476E-6
Sun1 Sun1tm1b(EUCOMM)Wtsi	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	8.925458132580388E-6
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) count	homozygote		increased large unstained cell number	8.964578228187747E-6
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	heterozygote		decreased circulating cholesterol level	8.9956411102321E-6
Cbr3 Cbr3em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Bone Mineral Density (excluding skull)	homozygote		decreased bone mineral density	9.073954970517661E-6
Gemin4 Gemin4em1(IMPC)Ics	Clinical Chemistry	Total protein	heterozygote		increased circulating total protein level	9.096852409129497E-6
Sun1 Sun1tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	9.141232112597208E-6
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	9.159306500805542E-6
Thra Thratm1b(EUCOMM)Wtsi	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	9.20016555028269E-6
Phf8 Phf8tm1dIcs	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	9.23450988921104E-6
Sdsl Sdsltm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Mineral Density (excluding skull)	homozygote		decreased bone mineral density	9.334871720056981E-6
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Heart Weight	Heart weight	homozygote		increased heart weight	9.350197615276556E-6
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Combined SHIRPA and Dysmorphology	Activity (body position)	hemizygote		abnormal locomotor behavior	9.386249985254835E-6
Diaph2 Diaph2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	hemizygote		increased circulating phosphate level	9.439117093279492E-6
Knstrn Knstrntm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Tremor	homozygote		tremors	9.466431947657838E-6
Ect2 Ect2tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Tremor	heterozygote		tremors	9.466431947657838E-6
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	NK Subsets (Q4)	homozygote		increased Ly6C-positive mature NK cell number	9.518370461591985E-6
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	9.533554475638084E-6
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Whole arena resting time	homozygote		hyperactivity	9.54080587689532E-6
Kcnip3 Kcnip3tm2b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	9.549515198159497E-6
Trpm6 Trpm6tm1b(KOMP)Wtsi	Hematology	Mean cell volume	heterozygote		decreased mean corpuscular volume	9.671048246673308E-6
Bnc2 Bnc2tm1b(KOMP)Wtsi	Indirect Calorimetry	Total water intake	heterozygote		decreased fluid intake	9.684613360150252E-6
Ptpra Ptpratm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		decreased prepulse inhibition	9.863021659839433E-6
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	9.88231386145344E-6
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Triglycerides	homozygote		decreased circulating triglyceride level	9.88283227343345E-6
Rnf10 Rnf10tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Unexpected behaviors	homozygote		abnormal behavior	1.0014443432737608E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Unexpected behaviors	homozygote		abnormal behavior	1.0014443432737608E-5
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Albumin	homozygote		increased circulating serum albumin level	1.013918881653808E-5
Gatad2b Gatad2btm1b(EUCOMM)Hmgu	Hematology	Monocyte differential count	heterozygote		increased monocyte cell number	1.0219275281997398E-5
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Eye Morphology	Retinal Blood Vessels Pattern	heterozygote		abnormal retina blood vessel morphology	1.0332038982596714E-5
Nae1 Nae1tm1b(EUCOMM)Wtsi	Hematology	Red blood cell count	heterozygote		decreased erythrocyte cell number	1.0416394616186153E-5
Cdh13 Cdh13tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	1.042567782860715E-5
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Activity (body position)	homozygote		abnormal locomotor behavior	1.0430635484226514E-5
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Open Field	Periphery average speed	homozygote		decreased locomotor activity	1.0469740118423942E-5
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat mass	homozygote		increased total body fat amount	1.058428915712284E-5
Hrh4 Hrh4tm1b(EUCOMM)Hmgu	Heart Weight	Heart weight	homozygote		decreased heart weight	1.0656730410119053E-5
Ahsa2 Ahsa2tm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	1.0739372555690352E-5
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Lower lip morphology	heterozygote		abnormal lip morphology	1.0764994840428699E-5
Saxo1 Saxo1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	1.090630394173786E-5
Atad2b Atad2btm1b(EUCOMM)Hmgu	Rotarod	Latency to fall mean	homozygote		abnormal motor capabilities/coordination/movement	1.0992743227689061E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	1.0994807780662086E-5
Atad2b Atad2btm1b(EUCOMM)Hmgu	Fear Conditioning	Context freezing total	homozygote		abnormal contextual conditioning behavior	1.111294659494888E-5
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		increased lean body mass	1.1143574738525786E-5
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair distribution - abdomen	homozygote		abnormal coat/ hair morphology	1.117024203267647E-5
Stat1 Stat1tm2b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Gait	homozygote		abnormal gait	1.117024203267647E-5
Stat1 Stat1tm2b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Contact righting	homozygote		impaired righting response	1.117024203267647E-5
Atad2b Atad2btm1b(EUCOMM)Hmgu	Fear Conditioning	% Context freezing total	homozygote		abnormal contextual conditioning behavior	1.1199888831470162E-5
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Eye Morphology	Retinal Blood Vessels	heterozygote		abnormal retina vasculature morphology	1.125704056903487E-5
Med25 Med25tm1b(KOMP)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	1.1331846508255694E-5
Phf8 Phf8tm1dIcs	Clinical Chemistry	HDL-cholesterol	homozygote		increased circulating HDL cholesterol level	1.1373213055776432E-5
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Echo	Fractional Shortening	homozygote		increased cardiac muscle contractility	1.1408652426325716E-5
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	1.1408977115934249E-5
Prrt2 Prrt2tm1b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	1.145380792877404E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Open Field	Distance travelled - total	homozygote		decreased locomotor activity	1.1472881851659622E-5
Septin3 Septin3tm1b(KOMP)Wtsi	Fear Conditioning	% Freezing duration habituation-1	heterozygote		abnormal locomotor behavior	1.1479242857603822E-5
Smc5 Smc5tm1b(KOMP)Wtsi	Hematology	Platelet count	heterozygote		thrombocytopenia	1.1552210708032362E-5
Knstrn Knstrntm1b(KOMP)Wtsi	Hematology	Hematocrit	homozygote		decreased hematocrit	1.159501880465541E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Eye Morphology	Right inner nuclear layer	homozygote		abnormal retina inner nuclear layer morphology	1.1634436305030249E-5
Arhgap24 Arhgap24tm1b(KOMP)Wtsi	Open Field	Center average speed	homozygote		decreased locomotor activity	1.163934575743042E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	homozygote		decreased prepulse inhibition	1.1642725439742208E-5
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	1.1678642295009922E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Number of rears - total	homozygote		decreased vertical activity	1.1680030183924828E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	1.1764404007408302E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Clinical Chemistry	Total bilirubin	heterozygote		increased circulating bilirubin level	1.18029793156893E-5
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) count	heterozygote		decreased large unstained cell number	1.1971235835517291E-5
Raf1 Raf1tm1b(EUCOMM)Wtsi	Eye Morphology	Lens Opacity	heterozygote		cataract	1.1973626897088252E-5
Raf1 Raf1tm1b(EUCOMM)Wtsi	Eye Morphology	Lens	heterozygote		abnormal lens morphology	1.1973626897088252E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	1.197641631733859E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Open Field	Whole arena average speed	homozygote		decreased locomotor activity	1.2173966752015986E-5
Stat1 Stat1tm2b(EUCOMM)Wtsi	Hematology	Basophil cell count	homozygote		increased basophil cell number	1.2448320376279298E-5
Pdpr Pdprtm1b(EUCOMM)Wtsi	Clinical Chemistry	Creatinine	homozygote		decreased circulating creatinine level	1.262571822735481E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Distance travelled - total	homozygote		hyperactivity	1.2629310731426813E-5
Dync1h1 Dync1h1tm1dIcs	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	heterozygote		impaired glucose tolerance	1.2810392945539206E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Eye Morphology	Corneal mineralization	homozygote		abnormal cornea morphology	1.2811648957722355E-5
Ncs1 Ncs1tm1b(EUCOMM)Hmgu	Eye Morphology	Corneal mineralization	homozygote		abnormal cornea morphology	1.2811648957722355E-5
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	1.2835975212510675E-5
Nxn Nxntm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration pre-cue-1	heterozygote		abnormal freezing behavior	1.2843146578234155E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Open Field	Periphery average speed	homozygote		hyperactivity	1.2876476830570027E-5
Pdpr Pdprtm1b(EUCOMM)Wtsi	Hematology	Large Unstained Cell (LUC) count	homozygote		decreased large unstained cell number	1.2922527275804896E-5
Iqce Iqcetm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	1.3049146218691021E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Hematology	Lymphocyte differential count	heterozygote		decreased lymphocyte cell number	1.3105845937388949E-5
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	1.3190811841923278E-5
Pax4 Pax4tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	1.334293483523652E-5
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Periphery resting time	heterozygote		hyperactivity	1.3370546184887644E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Eye Morphology	Right vitreous humor thickness	homozygote		abnormal vitreous body morphology	1.3379430129134562E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	1.3385397323872894E-5
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Clinical Chemistry	Creatinine	homozygote		increased circulating creatinine level	1.3534440768125933E-5
Klf12 Klf12tm1b(EUCOMM)Wtsi	Clinical Chemistry	Albumin	heterozygote		decreased circulating serum albumin level	1.357520159217529E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Limb grasp	heterozygote		limb grasping	1.3620233403344173E-5
Spn Spnem1(IMPC)Ics	Combined SHIRPA and Dysmorphology	Activity (body position)	homozygote		abnormal locomotor behavior	1.3649186257680412E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	NKT Cells (panel B)	heterozygote		increased NK T cell number	1.3758376553596463E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	1.378975957777584E-5
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Eye Morphology	Vitreous	heterozygote		abnormal vitreous body morphology	1.3831089745508507E-5
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	1.3846213732904289E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Open Field	Whole arena average speed	homozygote		hyperactivity	1.397236883349251E-5
Cav1 Cav1em2(IMPC)Ics	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	1.4016714885656256E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Electrocardiogram (ECG)	ST	homozygote		shortened ST segment	1.4063307389733382E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	1.418736337654991E-5
Ttc39a Ttc39atm1b(KOMP)Mbp	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	1.4313470273918938E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Clinical Chemistry	HDL-cholesterol	homozygote		decreased circulating HDL cholesterol level	1.4333223589346744E-5
Kif5c Kif5ctm1dIcs	Hematology	Lymphocyte differential count	heterozygote		decreased lymphocyte cell number	1.4341908354253974E-5
Dpp4 Dpp4tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.4361814464791678E-5
Atad2b Atad2btm1b(EUCOMM)Hmgu	Immunophenotyping	NKT Cells (panel B)	homozygote		decreased NK T cell number	1.4404467037820723E-5
Cfap119 Cfap119tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		decreased locomotor activity	1.44508812809363E-5
Gemin4 Gemin4em1(IMPC)Ics	Clinical Chemistry	HDL-cholesterol	heterozygote		increased circulating HDL cholesterol level	1.446285386919044E-5
Tti2 Tti2tm1b(KOMP)Wtsi	Hematology	Lymphocyte differential count	heterozygote		decreased lymphocyte cell number	1.459356371924514E-5
Taf2 Taf2tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	heterozygote		long tibia	1.466502362745814E-5
Klf12 Klf12tm1b(EUCOMM)Wtsi	Clinical Chemistry	Calcium	heterozygote		decreased circulating calcium level	1.4697864571644459E-5
Mapt Mapttm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	1.4713564269186463E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	1.474746113672154E-5
Rab19 Rab19tm1b(EUCOMM)Hmgu	Hematology	Eosinophil differential count	homozygote		increased eosinophil cell number	1.4789125089009758E-5
Bace2 Bace2tm1b(EUCOMM)Wtsi	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	1.4890239981468767E-5
Scaper Scapertm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	1.4894079868099652E-5
Cdh9 Cdh9tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	1.4903318515280262E-5
Ino80 Ino80tm1a(EUCOMM)Hmgu	Open Field	Periphery distance travelled	heterozygote		decreased locomotor activity	1.4987531358201522E-5
Phf8 Phf8tm1dIcs	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	1.511535174358869E-5
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	X-ray	Tibia length	heterozygote		short tibia	1.5465089745703153E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	Glucose	homozygote		increased circulating glucose level	1.5732601241325028E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	1.589205021446105E-5
Ackr3 Ackr3tm2b(EUCOMM)Wtsi	Hematology	Mean cell hemoglobin concentration	heterozygote		increased mean corpuscular hemoglobin concentration	1.596968104422558E-5
Casq1 Casq1tm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration pre-cue-2	homozygote		abnormal freezing behavior	1.5981964679667726E-5
Satb1 Satb1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	1.600015275471378E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Open Field	Distance travelled - total	heterozygote		hyperactivity	1.6068499462562613E-5
Ino80 Ino80tm1a(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Vocalization	heterozygote		abnormal vocalization	1.6107247574836947E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Combined SHIRPA and Dysmorphology	Locomotor activity	homozygote		increased exploration in new environment	1.6128087736433372E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	HDL-cholesterol	homozygote		decreased circulating HDL cholesterol level	1.613739732420072E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Hemoglobin	homozygote		decreased hemoglobin content	1.633769898035098E-5
Krt8 Krt8tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	heterozygote		decreased exploration in new environment	1.6420821339124814E-5
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	1.6446696463390253E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Startle response	homozygote		abnormal startle reflex	1.65947694767965E-5
Gatad2b Gatad2btm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	heterozygote		increased mean corpuscular volume	1.6742260413593613E-5
Cdc27 Cdc27tm1dIcs	Combined SHIRPA and Dysmorphology	Locomotor activity	heterozygote		decreased exploration in new environment	1.695775608823169E-5
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.697980405879207E-5
Padi3 Padi3tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Fat mass	homozygote		increased total body fat amount	1.706852162897121E-5
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	1.7172162188217044E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Calcium	heterozygote		increased circulating calcium level	1.7195565305883065E-5
Lmna Lmnatm1b(EUCOMM)Wtsi	Eye Morphology	Corneal ulcer	heterozygote		cornea ulcer	1.7295706129516475E-5
Thra Thratm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Limb grasp	heterozygote		limb grasping	1.7313295757048763E-5
Rcan1 Rcan1tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		increased lean body mass	1.7506827134639025E-5
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Whole arena resting time	heterozygote		hyperactivity	1.7523805581731722E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair distribution - abdomen	homozygote		abnormal coat/ hair morphology	1.7612108422326855E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Hematology	Neutrophil differential count	homozygote		increased neutrophil cell number	1.7706724975141697E-5
Bmp10 Bmp10tm3b(EUCOMM)Hmgu	Clinical Chemistry	Creatinine	heterozygote		decreased circulating creatinine level	1.770684502844233E-5
Padi3 Padi3tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		increased total body fat amount	1.7756503439159133E-5
Gpr108 Gpr108tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.8078917491948232E-5
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	1.8190345144830644E-5
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	1.8282247765455395E-5
Obp2a Obp2atm1b(EUCOMM)Wtsi	Eye Morphology	Optic Disc	homozygote		abnormal optic disk morphology	1.8346136130276136E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Eye Morphology	Left corneal thickness	homozygote		increased cornea thickness	1.8356902728555724E-5
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	1.839813921833411E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	ST	homozygote		prolonged ST segment	1.8479040591046214E-5
Setx Setxtm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	1.8515303963795304E-5
Nrp1 Nrp1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	heterozygote		decreased prepulse inhibition	1.8766659195534885E-5
Rab19 Rab19tm1b(EUCOMM)Hmgu	Clinical Chemistry	Calcium	homozygote		decreased circulating calcium level	1.882804099295754E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	CD8 CD44+CD62L+ T cells	heterozygote		decreased effector memory CD8-positive, alpha-beta T cell number	1.90593782463111E-5
Dnm1l Dnm1ltm1b(KOMP)Wtsi	Eye Morphology	Corneal mineralization	heterozygote		abnormal cornea morphology	1.920969589264132E-5
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Distance travelled - total	homozygote		decreased locomotor activity	1.927881021401845E-5
Il10ra Il10ratm1b(KOMP)Wtsi	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	1.9397006326471455E-5
Timm50 Timm50tm1b(EUCOMM)Wtsi	Eye Morphology	Right outer nuclear layer	heterozygote		abnormal retina outer nuclear layer morphology	1.9410363165661693E-5
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	homozygote		decreased prepulse inhibition	1.943623647093773E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Hematology	Lymphocyte cell count	heterozygote		decreased lymphocyte cell number	1.9448903913144022E-5
Med25 Med25tm1b(KOMP)Wtsi	Open Field	Center distance travelled	heterozygote		decreased locomotor activity	1.955591687874403E-5
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu	Open Field	Center permanence time	heterozygote		decreased thigmotaxis	1.9663586499518715E-5
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu	Open Field	Percentage center time	heterozygote		abnormal behavior	1.9663586499518715E-5
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu	Open Field	Periphery permanence time	heterozygote		decreased thigmotaxis	1.9663586499518715E-5
Dnm1l Dnm1ltm1b(KOMP)Wtsi	Eye Morphology	Persistence of hyaloid vascular system	heterozygote		persistence of hyaloid vascular system	1.9677985619637184E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	cDCs CD11b Type	homozygote		increased CD11b-high dendritic cell number	1.9738412447622977E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Hematology	White blood cell count	heterozygote		decreased leukocyte cell number	1.9783918105531484E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		increased startle reflex	1.9797322238446213E-5
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Open Field	Number of center entries	heterozygote		decreased locomotor activity	2.00394460989628E-5
Thra Thratm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration context-2	heterozygote		abnormal contextual conditioning behavior	2.0107378077227622E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Open Field	Periphery distance travelled	homozygote		decreased locomotor activity	2.0241448510205373E-5
Lca5l Lca5lem1(IMPC)Ics	Eye Morphology	Left total retinal thickness	homozygote		increased total retina thickness	2.0287658117013052E-5
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	2.0408395357662812E-5
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi	Clinical Chemistry	Cholesterol ratio	homozygote		abnormal cholesterol homeostasis	2.0471268726396374E-5
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Hematology	White blood cell count	heterozygote		decreased leukocyte cell number	2.051218325505033E-5
Dbn1 Dbn1tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	2.0568162653944455E-5
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Percentage center movement time	homozygote		decreased anxiety-related response	2.0605173631338403E-5
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi	Eye Morphology	Left inner nuclear layer	heterozygote		abnormal retina inner nuclear layer morphology	2.0616595065803267E-5
Lca5l Lca5lem1(IMPC)Ics	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	2.0688519725808874E-5
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	2.0697778381872922E-5
Atad2b Atad2btm1b(EUCOMM)Hmgu	Clinical Chemistry	HDL-cholesterol	homozygote		decreased circulating HDL cholesterol level	2.0819228666368872E-5
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI3	homozygote		increased prepulse inhibition	2.087506072712131E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Echo	Fractional Shortening	homozygote		decreased cardiac muscle contractility	2.090742054861039E-5
Nae1 Nae1tm1b(EUCOMM)Wtsi	Hematology	Mean cell volume	heterozygote		increased mean corpuscular volume	2.091642454615794E-5
Il10ra Il10ratm1b(KOMP)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	2.092267641273793E-5
Ptpra Ptpratm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	2.105966632370837E-5
Slx1b Slx1bem1(IMPC)Ics	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	2.1089494111947715E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean mass	homozygote		increased lean body mass	2.1089836081955582E-5
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Indirect Calorimetry	Total water intake	heterozygote		increased fluid intake	2.120043063769117E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Rotarod	Latency to fall mean	homozygote		abnormal motor capabilities/coordination/movement	2.122455225617159E-5
Pnpla1 Pnpla1tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Body length	heterozygote		increased body length	2.12670838664053E-5
Hmgn1 Hmgn1em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Fat mass	homozygote		increased total body fat amount	2.1376761651481502E-5
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI2	heterozygote		increased prepulse inhibition	2.140497963409871E-5
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi	Open Field	Number of rears - total	homozygote		increased vertical activity	2.153016612282954E-5
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi	Eye Morphology	Left vitreous humour thickness	homozygote		abnormal vitreous body morphology	2.158994902856648E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	2.1604686480714008E-5
Gp6 Gp6tm2b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Vibrissae - appearance	homozygote		abnormal vibrissa morphology	2.161036172765307E-5
Ackr3 Ackr3tm2b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	2.1612528144032694E-5
Epx Epxtm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		increased total body fat amount	2.172873428207822E-5
Spn Spnem1(IMPC)Ics	Fear Conditioning	% Freezing duration pre-cue-2	homozygote		abnormal freezing behavior	2.186751225963235E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	2.2079066184232943E-5
Wdr4 Wdr4em1(IMPC)Ics	X-ray	Tibia length	heterozygote		long tibia	2.2152969904709607E-5
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		hyperactivity	2.2182997781783342E-5
Cx3cl1 Cx3cl1em3(IMPC)Ics	Open Field	Periphery average speed	homozygote		decreased locomotor activity	2.2266607629717328E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Whole arena resting time	hemizygote		hyperactivity	2.25307830987731E-5
4933430I17Rik 4933430I17Riktm1b(EUCOMM)Wtsi	Echo	Fractional Shortening	homozygote		increased cardiac muscle contractility	2.2605288904742338E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Echo	HR	homozygote		increased heart rate	2.26402044063434E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Hematology	Neutrophil differential count	heterozygote		increased neutrophil cell number	2.279328509757761E-5
Trmt1 Trmt1tm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	heterozygote		increased mean corpuscular volume	2.2870282919029705E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	2.2968795747146942E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	heterozygote		short tibia	2.3021559172775596E-5
Smc5 Smc5tm1b(KOMP)Wtsi	Clinical Chemistry	Glucose	heterozygote		decreased circulating glucose level	2.3142183636082336E-5
Lmna Lmnatm1b(EUCOMM)Wtsi	X-ray	Tibia length	heterozygote		short tibia	2.3300115572055802E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Open Field	Number of rears - total	homozygote		increased vertical activity	2.333840893697925E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Number of center entries	hemizygote		hyperactivity	2.3547625460196286E-5
Setx Setxtm1b(EUCOMM)Wtsi	Immunophenotyping	NK Cells (panel B)	homozygote		increased NK cell number	2.3610671632923186E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	homozygote		decreased lymphocyte cell number	2.368184141232632E-5
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Rotarod	Latency to fall mean	homozygote		abnormal motor capabilities/coordination/movement	2.3826887627365068E-5
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Eye Morphology	Persistence of hyaloid vascular system	homozygote		persistence of hyaloid vascular system	2.3872731617302634E-5
Ppp4c Ppp4cem1(IMPC)Ics	Clinical Chemistry	Total bilirubin	heterozygote		increased circulating bilirubin level	2.4005099476198666E-5
Dusp11 Dusp11tm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	2.412226422165986E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	2.4408038370893337E-5
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Heart Weight	Tibia length	heterozygote		short tibia	2.442972981953062E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	2.4477414626744576E-5
Bmp10 Bmp10tm3b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	heterozygote		improved glucose tolerance	2.4488972485414706E-5
Setbp1 Setbp1tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Vocalization	heterozygote		abnormal vocalization	2.451576256135013E-5
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Vocalization	heterozygote		abnormal vocalization	2.451576256135013E-5
Dync1h1 Dync1h1tm1dIcs	Combined SHIRPA and Dysmorphology	Vocalization	heterozygote		abnormal vocalization	2.451576256135013E-5
App Apptm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		decreased grip strength	2.4608190869912505E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Eye Morphology	Cornea	heterozygote		abnormal cornea morphology	2.4881126591935754E-5
Nxn Nxntm1b(EUCOMM)Wtsi	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	2.4986988137243316E-5
Sh2b1 Sh2b1em1(IMPC)Ics	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	heterozygote		impaired glucose tolerance	2.501402013876941E-5
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	2.5059720428544097E-5
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	2.5109013222390786E-5
Cx3cl1 Cx3cl1em3(IMPC)Ics	Open Field	Number of rears - total	homozygote		decreased vertical activity	2.5169749278575182E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	2.5185985577991232E-5
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	2.5194836780428886E-5
Nfatc2ip Nfatc2ipem1(IMPC)Ics	Fear Conditioning	% Freezing duration habituation-2	homozygote		abnormal locomotor behavior	2.5218012524419464E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	2.525192940083798E-5
Nlk Nlktm2b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		increased startle reflex	2.5331486540380865E-5
Phf8 Phf8tm1dIcs	Eye Morphology	Left anterior chamber depth	hemizygote		abnormal eye anterior chamber depth	2.533893712097779E-5
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	2.5350831492687576E-5
Carmil2 Carmil2tm1b(KOMP)Mbp	Clinical Chemistry	Glucose	homozygote		increased circulating glucose level	2.540397508710157E-5
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	heterozygote		decreased lymphocyte cell number	2.5480925614829175E-5
Ackr3 Ackr3tm2b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	2.554289676481858E-5
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		decreased total body fat amount	2.5895415092236362E-5
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	homozygote		increased blood urea nitrogen level	2.6341882403357886E-5
Spn Spnem1(IMPC)Ics	Body Composition (DEXA lean/fat)	Body length	homozygote		increased body length	2.6448948119650595E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Fear Conditioning	Context freezing total	homozygote		abnormal contextual conditioning behavior	2.651647992024664E-5
Gp6 Gp6tm2b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		long tibia	2.7157115255249664E-5
Slx9 Slx9tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	2.7216181479161605E-5
Ackr3 Ackr3tm2b(EUCOMM)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	heterozygote		decreased grip strength	2.723376383073628E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration context-2	homozygote		abnormal contextual conditioning behavior	2.7247888283454813E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Fear Conditioning	% Context freezing total	homozygote		abnormal contextual conditioning behavior	2.7421301638241857E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	2.7552365281735547E-5
Taok2 Taok2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	2.7575853891903535E-5
Stradb Stradbtm1b(KOMP)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	2.803242750815116E-5
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	heterozygote		decreased lymphocyte cell number	2.804354517138563E-5
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Body length	homozygote		increased body length	2.8124086384195834E-5
Coq6 Coq6tm1b(EUCOMM)Hmgu	Eye Morphology	Vitreous	heterozygote		abnormal vitreous body morphology	2.815172410919331E-5
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	2.843182664946653E-5
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Hematology	Red blood cell count	heterozygote		decreased erythrocyte cell number	2.8440841560950503E-5
Iqce Iqcetm1b(EUCOMM)Hmgu	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	2.8754653612850234E-5
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	heterozygote		decreased blood urea nitrogen level	2.880163629015442E-5
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	2.884527202695608E-5
Trpm6 Trpm6tm1b(KOMP)Wtsi	Eye Morphology	Right anterior chamber depth	heterozygote		abnormal eye anterior chamber depth	2.8872324037365615E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Percentage center movement time	homozygote		increased anxiety-related response	2.8979502531001344E-5
Ncam2 Ncam2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	2.9014818210271187E-5
Trpm6 Trpm6tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	heterozygote		increased grip strength	2.9047268981230445E-5
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		increased total body fat amount	2.9261422241688706E-5
Fut4 Fut4em1(IMPC)Ics	Clinical Chemistry	Creatinine	homozygote		decreased circulating creatinine level	2.988352753163781E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Hematology	Platelet count	heterozygote		thrombocytosis	2.9917766369180754E-5
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Eye Morphology	Corneal mineralization	homozygote		abnormal cornea morphology	3.0092325687292032E-5
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair distribution - abdomen	homozygote		abnormal coat/ hair morphology	3.0192453777999617E-5
Il2rb Il2rbtm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Coat - hair distribution - back	homozygote		abnormal coat/ hair morphology	3.0192453777999617E-5
Bace2 Bace2tm1b(EUCOMM)Wtsi	Eye Morphology	Left corneal thickness	homozygote		increased cornea thickness	3.020923577423673E-5
Cdh9 Cdh9tm1b(KOMP)Wtsi	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	3.022550663445145E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	3.0516564947902225E-5
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	3.05534886138048E-5
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	3.0847160815028474E-5
Setbp1 Setbp1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total cholesterol	heterozygote		decreased circulating cholesterol level	3.107878001173958E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Hematology	White blood cell count	heterozygote		decreased leukocyte cell number	3.112374179181643E-5
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi	Clinical Chemistry	Glucose	homozygote		increased circulating glucose level	3.1304527510656044E-5
Capn10 Capn10tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	3.130564800812863E-5
Obp2a Obp2atm1b(EUCOMM)Wtsi	Eye Morphology	Retinal Blood Vessels Structure	homozygote		abnormal retina blood vessel morphology	3.1342064175987616E-5
App Apptm1b(KOMP)Wtsi	Clinical Chemistry	Calcium	heterozygote		increased circulating calcium level	3.1717412639409304E-5
Padi3 Padi3tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Lean mass	homozygote		decreased lean body mass	3.210710201528855E-5
Nae1 Nae1tm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	heterozygote		increased fasting circulating glucose level	3.2122363336384296E-5
Setx Setxtm1b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	homozygote		decreased lymphocyte cell number	3.2165520678972825E-5
4933430I17Rik 4933430I17Riktm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	3.2391257263952866E-5
Thra Thratm1b(EUCOMM)Wtsi	Eye Morphology	Right inner nuclear layer	heterozygote		abnormal retina inner nuclear layer morphology	3.2414602173957974E-5
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Retina (combined)	heterozygote		abnormal retina morphology	3.247526547056623E-5
Spn Spnem1(IMPC)Ics	Combined SHIRPA and Dysmorphology	Unexpected behaviors	homozygote		abnormal behavior	3.278563963249326E-5
Satb1 Satb1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Aspartate aminotransferase	heterozygote		increased circulating aspartate transaminase level	3.280003511463292E-5
Taf2 Taf2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	heterozygote		increased circulating cholesterol level	3.32303716277238E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Fear Conditioning	% Freezing duration pre-cue-2	homozygote		abnormal freezing behavior	3.329063838464208E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	homozygote		decreased blood urea nitrogen level	3.3341344533255324E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Fear Conditioning	% Cue freezing total	homozygote		abnormal cued conditioning behavior	3.3347758289892226E-5
Pdlim4 Pdlim4em1(IMPC)Ics	X-ray	Tibia length	homozygote		short tibia	3.3361844543833286E-5
Med25 Med25tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	3.356707384227775E-5
Gemin4 Gemin4em1(IMPC)Ics	Clinical Chemistry	Total cholesterol	heterozygote		increased circulating cholesterol level	3.373439176357351E-5
Il10ra Il10ratm1b(KOMP)Wtsi	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	homozygote		decreased blood urea nitrogen level	3.37474157277029E-5
Tmem50b Tmem50btm1b(EUCOMM)Wtsi	Eye Morphology	Right corneal thickness	homozygote		increased cornea thickness	3.377728717168793E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Fear Conditioning	Context freezing total	homozygote		abnormal contextual conditioning behavior	3.388512413948774E-5
Cav1 Cav1em2(IMPC)Ics	Echo	Fractional Shortening	homozygote		decreased cardiac muscle contractility	3.399742126930505E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Echo	LVIDd	homozygote		abnormal heart left ventricle morphology	3.408040356589481E-5
Nxn Nxntm1b(EUCOMM)Wtsi	X-ray	Digit integrity	heterozygote		abnormal digit morphology	3.414812817936763E-5
Rspo1 Rspo1tm2b(KOMP)Wtsi	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	3.4415155823808163E-5
Cidea Cideatm1b(EUCOMM)Hmgu	Eye Morphology	Cornea	homozygote		abnormal cornea morphology	3.443966124905273E-5
Cidea Cideatm1b(EUCOMM)Hmgu	Eye Morphology	Corneal opacity	homozygote		corneal opacity	3.443966124905273E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Immunophenotyping	Others	homozygote		immune system phenotype	3.450748044997454E-5
Dgkk Dgkkem1(IMPC)Ics	Clinical Chemistry	Alkaline phosphatase	hemizygote		increased circulating alkaline phosphatase level	3.451268275966868E-5
Smc5 Smc5tm1b(KOMP)Wtsi	Hematology	Hematocrit	heterozygote		decreased hematocrit	3.453335739322938E-5
Sdsl Sdsltm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Area	homozygote		abnormal bone structure	3.5000124626094475E-5
Tiam1 Tiam1tm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	3.500021921354346E-5
Mtmr12 Mtmr12tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	3.504618871374987E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration context-1	homozygote		abnormal contextual conditioning behavior	3.521352482493967E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	3.526182263158262E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Open Field	Periphery average speed	homozygote		hyperactivity	3.5380500776227564E-5
Rbfox1 Rbfox1tm1b(KOMP)Wtsi	X-ray	Tibia length	heterozygote		short tibia	3.549591565388255E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Fear Conditioning	% Context freezing total	homozygote		abnormal contextual conditioning behavior	3.574429501895793E-5
Rcan1 Rcan1tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		decreased total body fat amount	3.5845059755956754E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	3.5860870411852375E-5
Setx Setxtm1b(EUCOMM)Wtsi	Immunophenotyping	NK cells (panel A)	homozygote		increased NK cell number	3.587094761314802E-5
Cfap119 Cfap119tm1b(EUCOMM)Hmgu	Open Field	Distance travelled - total	homozygote		decreased locomotor activity	3.588647086871788E-5
Atad2b Atad2btm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	3.6223143979441375E-5
Maz Mazem1(IMPC)Ics	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	3.660851143649779E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration context-3	homozygote		abnormal contextual conditioning behavior	3.6643603380071E-5
Arhgap24 Arhgap24tm1b(KOMP)Wtsi	Open Field	Whole arena average speed	homozygote		decreased locomotor activity	3.6654753785114735E-5
Pdpr Pdprtm1b(EUCOMM)Wtsi	Open Field	Periphery distance travelled	homozygote		decreased locomotor activity	3.679681685753167E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration pre-cue-2	homozygote		abnormal freezing behavior	3.680581721710041E-5
Krt8 Krt8tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	heterozygote		increased prepulse inhibition	3.7072255508974195E-5
Cdh13 Cdh13tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	3.71381247532554E-5
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu	Open Field	Percentage center movement time	heterozygote		decreased anxiety-related response	3.736685903277248E-5
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Creatinine	homozygote		decreased circulating creatinine level	3.7485326174646616E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QT	homozygote		prolonged QT interval	3.757956437766552E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Open Field	Percentage center movement time	homozygote		increased anxiety-related response	3.766411464312114E-5
Nol8 Nol8tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	heterozygote		increased fasting circulating glucose level	3.7785623135278E-5
Cdh13 Cdh13tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QT	homozygote		shortened QT interval	3.793064024648629E-5
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	3.8155158108565956E-5
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Indirect Calorimetry	Respiratory Exchange Ratio	homozygote		decreased respiratory quotient	3.817743345280178E-5
Dusp11 Dusp11tm1b(EUCOMM)Wtsi	Clinical Chemistry	Aspartate aminotransferase	homozygote		increased circulating aspartate transaminase level	3.834109884337522E-5
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Clinical Chemistry	Total bilirubin	homozygote		increased circulating bilirubin level	3.857468982459977E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	3.8610363844782114E-5
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	heterozygote		short tibia	3.8777972804382443E-5
Mapt Mapttm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	3.888334322255105E-5
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	3.8938323996262625E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Open Field	Center distance travelled	heterozygote		hyperactivity	3.893909524776973E-5
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Echo	LVPWd	heterozygote		thick ventricular wall	3.897841088473797E-5
Il10ra Il10ratm1b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		decreased startle reflex	3.900188676198013E-5
Gatad2b Gatad2btm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	3.929771628463641E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Heart Weight	Heart weight	homozygote		increased heart weight	3.9507394831161946E-5
Rab19 Rab19tm1b(EUCOMM)Hmgu	Eye Morphology	Corneal opacity	homozygote		corneal opacity	3.9754773752065375E-5
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	3.979641405749135E-5
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	3.982842463301495E-5
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	3.9882739656604826E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Hematology	White blood cell count	homozygote		increased leukocyte cell number	3.997231033281423E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Open Field	Whole arena resting time	heterozygote		hyperactivity	3.999221007688902E-5
Fut4 Fut4em1(IMPC)Ics	Fear Conditioning	% Freezing duration pre-cue-2	homozygote		abnormal freezing behavior	4.0018650906858966E-5
Rwdd3 Rwdd3tm1b(KOMP)Wtsi	Electrocardiogram (ECG)	ST	heterozygote		prolonged ST segment	4.0126466046785936E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	4.0144856029655784E-5
Prkab1 Prkab1tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	4.0181708754971623E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Fear Conditioning	Context freezing total	homozygote		abnormal contextual conditioning behavior	4.081851875525899E-5
Thra Thratm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration context-3	heterozygote		abnormal contextual conditioning behavior	4.083125168108381E-5
Gemin4 Gemin4em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Fat mass	heterozygote		increased total body fat amount	4.089831418241374E-5
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Eye Morphology	Retina (combined)	heterozygote		abnormal retina morphology	4.113533577765338E-5
Cdc27 Cdc27tm1dIcs	Body Composition (DEXA lean/fat)	Fat/Body weight	heterozygote		increased total body fat amount	4.121931124245748E-5
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QT	heterozygote		prolonged QT interval	4.124428232898936E-5
Cebpz Cebpztm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Fat/Body weight	heterozygote		increased total body fat amount	4.1449846321484074E-5
Gemin4 Gemin4em1(IMPC)Ics	Rotarod	Latency to fall mean	heterozygote		abnormal motor capabilities/coordination/movement	4.1676270484458655E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Periphery resting time	homozygote		hyperactivity	4.168168379692361E-5
Smc5 Smc5tm1b(KOMP)Wtsi	Hematology	Red blood cell count	heterozygote		decreased erythrocyte cell number	4.171723412582651E-5
Ncam2 Ncam2tm1b(EUCOMM)Hmgu	Echo	Fractional Shortening	homozygote		decreased cardiac muscle contractility	4.1721901652636006E-5
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	4.194873326923698E-5
Coq6 Coq6tm1b(EUCOMM)Hmgu	Eye Morphology	Corneal mineralization	heterozygote		abnormal cornea morphology	4.199800605420023E-5
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	4.2156854760833085E-5
Cav1 Cav1em2(IMPC)Ics	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	4.23461569880601E-5
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Cholesterol ratio	homozygote		abnormal cholesterol homeostasis	4.2569226934574544E-5
Olig1 Olig1em2(IMPC)Ics	Clinical Chemistry	Phosphorus	homozygote		decreased circulating phosphate level	4.2665720684453845E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		increased lean body mass	4.284303213353269E-5
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Hematology	Hematocrit	heterozygote		decreased hematocrit	4.30039617640432E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Locomotor activity	heterozygote		decreased exploration in new environment	4.3062893382739276E-5
Iqce Iqcetm1b(EUCOMM)Hmgu	Clinical Chemistry	Glucose	homozygote		decreased circulating glucose level	4.306802657083608E-5
Obp2a Obp2atm1b(EUCOMM)Wtsi	Eye Morphology	Retinal Blood Vessels	homozygote		abnormal retina vasculature morphology	4.315025944379158E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Fear Conditioning	% Context freezing total	homozygote		abnormal contextual conditioning behavior	4.355964483693242E-5
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Eye Morphology	Vitreous	homozygote		abnormal vitreous body morphology	4.3638021452352405E-5
Bnc2 Bnc2tm1b(KOMP)Wtsi	Eye Morphology	Right corneal thickness	heterozygote		increased cornea thickness	4.366265420685522E-5
Plscr1 Plscr1tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QRS	homozygote		shortened QRS complex duration	4.372711919131689E-5
Gpr101 Gpr101tm1b(KOMP)Mbp	Open Field	Center resting time	hemizygote		decreased locomotor activity	4.3916872527915984E-5
Kctd15 Kctd15tm1b(EUCOMM)Wtsi	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	heterozygote		increased blood urea nitrogen level	4.4063577661290765E-5
Ino80 Ino80tm1a(EUCOMM)Hmgu	Electrocardiogram (ECG)	QRS	heterozygote		prolonged QRS complex duration	4.415403964230791E-5
Mmp11 Mmp11tm1b(EUCOMM)Hmgu	Hematology	Mean corpuscular hemoglobin	homozygote		decreased mean corpuscular hemoglobin	4.4194897782290354E-5
Cd276 Cd276tm2b(EUCOMM)Hmgu	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	4.4339452870190144E-5
Mapt Mapttm1b(EUCOMM)Hmgu	Indirect Calorimetry	Total water intake	homozygote		increased fluid intake	4.454005102161318E-5
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Clinical Chemistry	HDL-cholesterol	heterozygote		increased circulating HDL cholesterol level	4.4631622586166486E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Periphery permanence time	homozygote		increased thigmotaxis	4.470697240321897E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Percentage center time	homozygote		abnormal behavior	4.470697240321897E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Center permanence time	homozygote		increased thigmotaxis	4.470697240321897E-5
Gorasp1 Gorasp1tm1b(KOMP)Wtsi	Clinical Chemistry	Creatinine	heterozygote		decreased circulating creatinine level	4.4773325498681515E-5
Capn10 Capn10tm1b(EUCOMM)Wtsi	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	4.480769712245092E-5
Nfatc2ip Nfatc2ipem1(IMPC)Ics	Hematology	Eosinophil differential count	homozygote		increased eosinophil cell number	4.488696140469983E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	4.489393177209422E-5
Arhgap24 Arhgap24tm1b(KOMP)Wtsi	Open Field	Periphery average speed	homozygote		decreased locomotor activity	4.505982724367641E-5
Dyrk2 Dyrk2em1(IMPC)Ics	Hematology	Large Unstained Cell (LUC) differential count	heterozygote		decreased large unstained cell number	4.506540426518768E-5
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	4.517448542173952E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Eye Morphology	Retina (combined)	homozygote		abnormal retina morphology	4.5248867536429316E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	NK Cells (panel B)	heterozygote		increased NK cell number	4.525945769273676E-5
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	4.5585897169075906E-5
Med25 Med25tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	heterozygote		increased total body fat amount	4.586187787936069E-5
Thra Thratm1b(EUCOMM)Wtsi	Fear Conditioning	% Context freezing total	heterozygote		abnormal contextual conditioning behavior	4.610780524672009E-5
Dusp11 Dusp11tm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	4.618667662725784E-5
Carmil2 Carmil2tm1b(KOMP)Mbp	Clinical Chemistry	Cholesterol ratio	homozygote		abnormal cholesterol homeostasis	4.6235392801463604E-5
Tiam1 Tiam1tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		decreased locomotor activity	4.647257082979195E-5
Phf8 Phf8tm1dIcs	Echo	LVIDd	homozygote		abnormal heart left ventricle morphology	4.647698006010614E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	4.662766514229588E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Right inner nuclear layer	homozygote		abnormal retina inner nuclear layer morphology	4.6986468078102916E-5
Trpm6 Trpm6tm1b(KOMP)Wtsi	Clinical Chemistry	Phosphorus	heterozygote		decreased circulating phosphate level	4.7057172196218744E-5
Stat1 Stat1tm2b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	BMC/Body weight	homozygote		decreased bone mineral content	4.7091434680623934E-5
Thra Thratm1b(EUCOMM)Wtsi	Heart Weight	Tibia length	heterozygote		short tibia	4.726017141365446E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	X-ray	Tibia length	homozygote		short tibia	4.767148493556306E-5
Ptpra Ptpratm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	4.767163409269415E-5
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Glucose	heterozygote		increased circulating glucose level	4.782039832207374E-5
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	4.782497126143426E-5
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	4.789915692526847E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Albumin	homozygote		decreased circulating serum albumin level	4.8121826694114134E-5
Taf2 Taf2tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength normalised against body weight	heterozygote		decreased grip strength	4.8132471420103684E-5
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	4.850427285418846E-5
Nlk Nlktm2b(KOMP)Wtsi	Clinical Chemistry	Alkaline phosphatase	heterozygote		increased circulating alkaline phosphatase level	4.877387618762441E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	4.951441951561719E-5
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Hematology	White blood cell count	heterozygote		decreased leukocyte cell number	4.9642669182503596E-5
Tmem63b Tmem63btm1b(EUCOMM)Wtsi	Open Field	Periphery resting time	heterozygote		hyperactivity	4.974851617589593E-5
Lcp2 Lcp2tm1b(KOMP)Wtsi	Eye Morphology	Lens Opacity	heterozygote		cataract	4.979671575711109E-5
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Heart Weight	Tibia length	heterozygote		short tibia	4.9843638407764956E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Alanine aminotransferase	homozygote		increased circulating alanine transaminase level	5.014327325625345E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Clinical Chemistry	Creatinine	homozygote		increased circulating creatinine level	5.015170609112829E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	5.029118256061338E-5
Cidea Cideatm1b(EUCOMM)Hmgu	Eye Morphology	Right outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	5.076361776445992E-5
Ttc39a Ttc39atm1b(KOMP)Mbp	Hematology	Mean cell hemoglobin concentration	homozygote		decreased mean corpuscular hemoglobin concentration	5.0981310778297484E-5
Ect2 Ect2tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	5.1078703108942136E-5
Gp6 Gp6tm2b(EUCOMM)Hmgu	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	5.1108527259202674E-5
Thra Thratm1b(EUCOMM)Wtsi	Fear Conditioning	Context freezing total	heterozygote		abnormal contextual conditioning behavior	5.110908023198135E-5
Pax4 Pax4tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	heterozygote		increased circulating total protein level	5.130821227794513E-5
Cx3cl1 Cx3cl1em3(IMPC)Ics	Open Field	Distance travelled - total	homozygote		decreased locomotor activity	5.136207983014174E-5
Padi3 Padi3tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		decreased lean body mass	5.137575135449879E-5
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		decreased grip strength	5.1467774028424174E-5
Ttc39a Ttc39atm1b(KOMP)Mbp	Heart Weight	Heart weight	homozygote		increased heart weight	5.157957275514491E-5
Cidea Cideatm1b(EUCOMM)Hmgu	Clinical Chemistry	Alkaline phosphatase	homozygote		increased circulating alkaline phosphatase level	5.169043652131222E-5
Ahsa2 Ahsa2tm1b(EUCOMM)Wtsi	Eye Morphology	Corneal mineralization	homozygote		abnormal cornea morphology	5.171763768885285E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Immunophenotyping	CD24+ CD4 T cells	homozygote		immune system phenotype	5.1778231863863766E-5
Obp2a Obp2atm1b(EUCOMM)Wtsi	Eye Morphology	Persistence of hyaloid vascular system	homozygote		persistence of hyaloid vascular system	5.184971814742312E-5
Gpr108 Gpr108tm1b(EUCOMM)Hmgu	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	5.187550050322898E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	5.197489736019634E-5
Tmem50b Tmem50btm1b(EUCOMM)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	homozygote		decreased grip strength	5.198881990509108E-5
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Head bobbing	homozygote		head bobbing	5.202514148550108E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Gait	homozygote		abnormal gait	5.202514148550108E-5
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Fat/Body weight	homozygote		increased total body fat amount	5.2333856729092076E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Clinical Chemistry	Total protein	heterozygote		increased circulating total protein level	5.279888864606619E-5
Maz Mazem1(IMPC)Ics	Combined SHIRPA and Dysmorphology	Head morphology	heterozygote		abnormal head morphology	5.284534563543275E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Retinal Blood Vessels	homozygote		abnormal retina vasculature morphology	5.341996075003408E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Retinal Blood Vessels Pattern	homozygote		abnormal retina blood vessel morphology	5.341996075003408E-5
Krt8 Krt8tm1b(EUCOMM)Hmgu	Hematology	Neutrophil differential count	heterozygote		increased neutrophil cell number	5.3791558457305655E-5
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration pre-cue-1	heterozygote		abnormal freezing behavior	5.390495789470151E-5
Rspo1 Rspo1tm2b(KOMP)Wtsi	Hematology	Lymphocyte cell count	homozygote		increased lymphocyte cell number	5.397247150540352E-5
Setx Setxtm1b(EUCOMM)Wtsi	Immunophenotyping	Monocytes	homozygote		increased monocyte cell number	5.398517896537669E-5
Rab19 Rab19tm1b(EUCOMM)Hmgu	Fear Conditioning	Context freezing total	homozygote		abnormal contextual conditioning behavior	5.4062529670773074E-5
Iqce Iqcetm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	5.4412666941061616E-5
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Whole arena resting time	homozygote		decreased locomotor activity	5.4696822189725935E-5
Saxo1 Saxo1tm1b(EUCOMM)Hmgu	Hematology	Eosinophil differential count	homozygote		increased eosinophil cell number	5.496959784068167E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	5.507819514605217E-5
Nol8 Nol8tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		increased startle reflex	5.509112816071138E-5
Cav1 Cav1em2(IMPC)Ics	Echo	HR	homozygote		increased heart rate	5.531769056688063E-5
Prdm10 Prdm10tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Bone Mineral Content (excluding skull)	heterozygote		decreased bone mineral content	5.561772923101671E-5
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Hematology	Hematocrit	homozygote		decreased hematocrit	5.611987944575958E-5
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Triglycerides	homozygote		increased circulating triglyceride level	5.6264289014507085E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Heart Weight	Tibia length	homozygote		short tibia	5.631587919197045E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	5.6330238294322044E-5
Prrt2 Prrt2tm1b(KOMP)Wtsi	Clinical Chemistry	Alkaline phosphatase	homozygote		decreased circulating alkaline phosphatase level	5.63753601454664E-5
Cdh9 Cdh9tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	5.6529130233684555E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	BMC/Body weight	homozygote		decreased bone mineral content	5.653870175592601E-5
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.6539000070188195E-5
Adipor1 Adipor1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	18kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	5.6539000070188195E-5
Cd276 Cd276tm2b(EUCOMM)Hmgu	Open Field	Periphery resting time	homozygote		hyperactivity	5.6932894949568436E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Open Field	Periphery average speed	hemizygote		hyperactivity	5.803820022265427E-5
Gp6 Gp6tm2b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		long tibia	5.8081197494175285E-5
Ncs1 Ncs1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb grip strength measurement mean	homozygote		decreased grip strength	5.826607230119407E-5
Trpm6 Trpm6tm1b(KOMP)Wtsi	Hematology	Mean cell volume	heterozygote		decreased mean corpuscular volume	5.8288609579904005E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	NKT Cells (panel B)	heterozygote		increased NK T cell number	5.853914626641199E-5
Gpr101 Gpr101tm1b(KOMP)Mbp	Open Field	Center permanence time	hemizygote		decreased thigmotaxis	5.865620187250897E-5
Gpr101 Gpr101tm1b(KOMP)Mbp	Open Field	Percentage center time	hemizygote		abnormal behavior	5.865620187250897E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Periphery permanence time	homozygote		increased thigmotaxis	5.872579640708864E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Percentage center time	homozygote		abnormal behavior	5.872579640708864E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Center permanence time	homozygote		increased thigmotaxis	5.872579640708864E-5
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Tail - morphology	homozygote		abnormal tail morphology	5.873131158296019E-5
Gpr101 Gpr101tm1b(KOMP)Mbp	Open Field	Periphery permanence time	hemizygote		decreased thigmotaxis	5.873394547961652E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Immunophenotyping	DN CD44+CD62L- NKT cells	heterozygote		increased memory-marker CD4-negative NK T cell number	5.873933696420863E-5
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		decreased prepulse inhibition	5.884501297259703E-5
Rab19 Rab19tm1b(EUCOMM)Hmgu	Fear Conditioning	% Context freezing total	homozygote		abnormal contextual conditioning behavior	5.8979607274523005E-5
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	homozygote		decreased mean corpuscular volume	5.938364483881742E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair distribution - back	homozygote		abnormal coat/ hair morphology	5.960176349617541E-5
Ncs1 Ncs1tm1b(EUCOMM)Hmgu	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	5.9659458202077076E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Open Field	Percentage center movement time	homozygote		increased anxiety-related response	5.97341604589019E-5
Iah1 Iah1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - Global	homozygote		increased prepulse inhibition	5.979651541565545E-5
Klf12 Klf12tm1b(EUCOMM)Wtsi	Eye Morphology	Left inner nuclear layer	heterozygote		abnormal retina inner nuclear layer morphology	5.9856538427993655E-5
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Eye Morphology	Retinal Blood Vessels	heterozygote		abnormal retina vasculature morphology	5.997620246489532E-5
Gatad2b Gatad2btm1b(EUCOMM)Hmgu	Open Field	Whole arena resting time	heterozygote		decreased locomotor activity	6.005756222293712E-5
Plscr1 Plscr1tm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	homozygote		increased startle reflex	6.016172483214177E-5
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Vocalization	heterozygote		abnormal vocalization	6.0367292462615296E-5
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi	Eye Morphology	Retinal Blood Vessels Pattern	heterozygote		abnormal retina blood vessel morphology	6.050615411368199E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Open Field	Periphery distance travelled	homozygote		hyperactivity	6.0701535403495654E-5
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu	Echo	Fractional Shortening	homozygote		decreased cardiac muscle contractility	6.080992170609534E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	Triglycerides	homozygote		decreased circulating triglyceride level	6.097966979723424E-5
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	6.114081043051556E-5
Mocos Mocosem2(IMPC)Ics	Clinical Chemistry	HDL-cholesterol	heterozygote		increased circulating HDL cholesterol level	6.144158396637067E-5
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	6.146739178802818E-5
Med25 Med25tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Fat mass	heterozygote		increased total body fat amount	6.186772952787578E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Clinical Chemistry	Total cholesterol	homozygote		decreased circulating cholesterol level	6.197081529535353E-5
Atad2b Atad2btm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		hyperactivity	6.202638178365305E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Whole arena average speed	homozygote		decreased locomotor activity	6.249848229344934E-5
Klhl29 Klhl29tm1b(EUCOMM)Hmgu	Echo	Fractional Shortening	homozygote		increased cardiac muscle contractility	6.261807720875368E-5
Lca5l Lca5lem1(IMPC)Ics	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	6.291184399742633E-5
Pdpr Pdprtm1b(EUCOMM)Wtsi	Hematology	Hematocrit	homozygote		increased hematocrit	6.304894486675039E-5
Lcp2 Lcp2tm1b(KOMP)Wtsi	Eye Morphology	Lens	heterozygote		abnormal lens morphology	6.318731902865693E-5
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration habituation-1	heterozygote		abnormal locomotor behavior	6.323367415461689E-5
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		decreased startle reflex	6.323568231891841E-5
Nrp1 Nrp1tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	6.327198207145557E-5
Padi3 Padi3tm1b(KOMP)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	6.327198207145557E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Hematology	Neutrophil cell count	homozygote		increased neutrophil cell number	6.342614506138489E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		increased grip strength	6.352374475682154E-5
Ncs1 Ncs1tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	6.365862645907328E-5
Krt8 Krt8tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	heterozygote		improved glucose tolerance	6.366117304423824E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		decreased grip strength	6.369144102791324E-5
Timm50 Timm50tm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	6.379943079082295E-5
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Open Field	Periphery distance travelled	homozygote		decreased locomotor activity	6.397537799784914E-5
Cfap119 Cfap119tm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		decreased locomotor activity	6.420024874387309E-5
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu	Open Field	Periphery distance travelled	homozygote		hyperactivity	6.462683086283505E-5
Cdk8 Cdk8tm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration pre-cue-2	heterozygote		abnormal freezing behavior	6.555773870786652E-5
Dusp11 Dusp11tm1b(EUCOMM)Wtsi	Eye Morphology	Corneal mineralization	homozygote		abnormal cornea morphology	6.583507638424635E-5
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Eye Morphology	Vitreous	heterozygote		abnormal vitreous body morphology	6.584291986655444E-5
Cd19 Cd19em2(IMPC)Ics	Hematology	Monocyte cell count	homozygote		increased monocyte cell number	6.589305849047378E-5
Iqce Iqcetm1b(EUCOMM)Hmgu	X-ray	Tibia length	homozygote		short tibia	6.592855788767338E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Immunophenotyping	CD24+ CD8 T cells	homozygote		immune system phenotype	6.645872053923085E-5
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	heterozygote		decreased blood urea nitrogen level	6.646328256465495E-5
Ctsd Ctsdtm1b(EUCOMM)Wtsi	Hematology	Hematocrit	heterozygote		decreased hematocrit	6.647062400588766E-5
Nxn Nxntm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration habituation-1	heterozygote		abnormal locomotor behavior	6.677986675640568E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Grip Strength	Forelimb and hindlimb grip strength measurement mean	homozygote		decreased grip strength	6.680808292003348E-5
Krt8 Krt8tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	heterozygote		improved glucose tolerance	6.71053203404881E-5
Hrh4 Hrh4tm1b(EUCOMM)Hmgu	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	6.727696018060669E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Eye Morphology	Left outer nuclear layer	homozygote		abnormal retina outer nuclear layer morphology	6.756473158020526E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Total protein	homozygote		decreased circulating total protein level	6.77038260619156E-5
Cd19 Cd19em2(IMPC)Ics	Hematology	Lymphocyte differential count	homozygote		decreased lymphocyte cell number	6.782874697819352E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Hematology	Hematocrit	homozygote		decreased hematocrit	6.832493818365037E-5
Snx29 Snx29tm1b(EUCOMM)Hmgu	Echo	HR	homozygote		decreased heart rate	6.833506631664932E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Open Field	Number of center entries	homozygote		decreased locomotor activity	6.83419857523404E-5
Rbck1 Rbck1tm1b(EUCOMM)Hmgu	Open Field	Number of center entries	heterozygote		hyperactivity	6.856184336356819E-5
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu	Hematology	Lymphocyte cell count	homozygote		decreased lymphocyte cell number	6.87696083332412E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration context-1	homozygote		abnormal contextual conditioning behavior	6.886947085149586E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Electrocardiogram (ECG)	QT	homozygote		shortened QT interval	6.892361852806062E-5
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu	Eye Morphology	Left corneal thickness	homozygote		increased cornea thickness	6.899567233631387E-5
Knstrn Knstrntm1b(KOMP)Wtsi	Eye Morphology	Corneal ulcer	homozygote		cornea ulcer	6.904005567776039E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		decreased prepulse inhibition	6.932808173587546E-5
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Limb grasp	homozygote		limb grasping	6.948360532987863E-5
Dusp11 Dusp11tm1b(EUCOMM)Wtsi	Electrocardiogram (ECG)	QRS	homozygote		prolonged QRS complex duration	6.958103767829016E-5
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	heterozygote		decreased total retina thickness	6.96094284649007E-5
Rwdd3 Rwdd3tm1b(KOMP)Wtsi	Grip Strength	Forelimb grip strength normalised against body weight	heterozygote		decreased grip strength	6.966642831685022E-5
Synpo2 Synpo2tm1b(EUCOMM)Wtsi	Electrocardiogram (ECG)	PR	heterozygote		prolonged PR interval	6.967224180698395E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	homozygote		hyperactivity	6.978354213060811E-5
Ptpra Ptpratm1b(EUCOMM)Hmgu	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	6.98599687893875E-5
Rab19 Rab19tm1b(EUCOMM)Hmgu	Eye Morphology	Left corneal thickness	homozygote		increased cornea thickness	6.987411325098947E-5
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		short tibia	6.997204036451876E-5
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	7.017353345872834E-5
Dcp2 Dcp2tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - head	heterozygote		abnormal coat/hair pigmentation	7.030265260254964E-5
Obp2a Obp2atm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - head	homozygote		abnormal coat/hair pigmentation	7.030265260254964E-5
Dcp2 Dcp2tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - abdomen	heterozygote		abnormal coat/hair pigmentation	7.030265260254964E-5
Obp2a Obp2atm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color - back	homozygote		abnormal coat/hair pigmentation	7.030265260254964E-5
Dcp2 Dcp2tm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - back	heterozygote		abnormal coat/hair pigmentation	7.030265260254964E-5
Thra Thratm1b(EUCOMM)Wtsi	Open Field	Number of rears - total	heterozygote		increased vertical activity	7.088026904966682E-5
Exd1 Exd1tm1b(EUCOMM)Hmgu	Heart Weight	Heart weight	homozygote		increased heart weight	7.22105469321832E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Clinical Chemistry	Calcium	homozygote		decreased circulating calcium level	7.242373249027878E-5
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) differential count	homozygote		decreased large unstained cell number	7.245234155561775E-5
Phf8 Phf8tm1dIcs	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	hemizygote		improved glucose tolerance	7.245798769872636E-5
Plekhg3 Plekhg3tm1b(EUCOMM)Hmgu	Eye Morphology	Left anterior chamber depth	homozygote		abnormal eye anterior chamber depth	7.299032586161047E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Gait	homozygote		abnormal gait	7.322654710151255E-5
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu	Combined SHIRPA and Dysmorphology	Gait	homozygote		abnormal gait	7.322654710151255E-5
Olig1 Olig1em2(IMPC)Ics	Open Field	Distance travelled - total	homozygote		hyperactivity	7.338894647546113E-5
Il18rap Il18raptm1b(KOMP)Wtsi	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	7.363212353084236E-5
Enpp4 Enpp4em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Bone Mineral Density (excluding skull)	homozygote		decreased bone mineral density	7.36399888410233E-5
Fpr3 Fpr3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	7.365939381998032E-5
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Fat mass	homozygote		decreased total body fat amount	7.367989019257948E-5
Pgam5 Pgam5tm1b(EUCOMM)Wtsi	Clinical Chemistry	HDL-cholesterol	homozygote		decreased circulating HDL cholesterol level	7.372056279564276E-5
Phf8 Phf8tm1dIcs	Clinical Chemistry	HDL-cholesterol	hemizygote		increased circulating HDL cholesterol level	7.3730327130761E-5
Bphl Bphltm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration pre-cue-2	homozygote		abnormal freezing behavior	7.374544657068327E-5
Lca5l Lca5lem1(IMPC)Ics	Eye Morphology	Right total retinal thickness	homozygote		increased total retina thickness	7.378172449534759E-5
Phf8 Phf8tm1dIcs	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	7.381735485978425E-5
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Red blood cell count	heterozygote		decreased erythrocyte cell number	7.395678403554484E-5
Dgkk Dgkkem1(IMPC)Ics	Fear Conditioning	% Freezing duration habituation-1	hemizygote		abnormal locomotor behavior	7.447073585353792E-5
Saxo1 Saxo1tm1b(EUCOMM)Hmgu	Eye Morphology	Right vitreous humor thickness	homozygote		abnormal vitreous body morphology	7.515551260439679E-5
Maz Mazem1(IMPC)Ics	Combined SHIRPA and Dysmorphology	Locomotor activity	heterozygote		decreased exploration in new environment	7.54422799218446E-5
Mx2 Mx2em1(IMPC)Ics	Eye Morphology	Left inner nuclear layer	homozygote		abnormal retina inner nuclear layer morphology	7.54485881770961E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Open Field	Number of center entries	homozygote		decreased locomotor activity	7.576558709843084E-5
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI1	homozygote		increased prepulse inhibition	7.585744606330991E-5
Pdpr Pdprtm1b(EUCOMM)Wtsi	Open Field	Whole arena resting time	homozygote		decreased locomotor activity	7.594541239086539E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Center distance travelled	homozygote		decreased locomotor activity	7.649995677638799E-5
Dgkk Dgkkem1(IMPC)Ics	Clinical Chemistry	HDL-cholesterol	hemizygote		increased circulating HDL cholesterol level	7.76030428824015E-5
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	7.801272295182571E-5
Ap4e1 Ap4e1tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	7.803125481586903E-5
Arhgap24 Arhgap24tm1b(KOMP)Wtsi	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	7.844930223654956E-5
Sun1 Sun1tm1b(EUCOMM)Wtsi	Clinical Chemistry	Phosphorus	homozygote		increased circulating phosphate level	7.850059046177194E-5
Cfap119 Cfap119tm1b(EUCOMM)Hmgu	Open Field	Number of rears - total	homozygote		decreased vertical activity	7.850596739444882E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Percentage center movement time	homozygote		increased anxiety-related response	7.898405601736158E-5
Ackr3 Ackr3tm2b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Tremor	heterozygote		tremors	7.931794243631884E-5
Dnal4 Dnal4tm1b(EUCOMM)Wtsi	Combined SHIRPA and Dysmorphology	Tremor	heterozygote		tremors	7.931794243631884E-5
Ahsa2 Ahsa2tm1b(EUCOMM)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	7.942496449686587E-5
Knstrn Knstrntm1b(KOMP)Wtsi	Eye Morphology	Cornea	homozygote		abnormal cornea morphology	7.955614273669198E-5
Elapor1 Elapor1tm1b(EUCOMM)Hmgu	Hematology	Lymphocyte cell count	heterozygote		decreased lymphocyte cell number	7.961881783558056E-5
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi	Open Field	Center distance travelled	homozygote		decreased locomotor activity	7.968868885654956E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Hematology	Red blood cell count	homozygote		decreased erythrocyte cell number	7.980723603395745E-5
Cbr3 Cbr3em1(IMPC)Ics	Open Field	Number of rears - total	homozygote		decreased vertical activity	7.981539965840057E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Body length	homozygote		decreased body length	8.00607303972356E-5
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Eye Morphology	Right anterior chamber depth	homozygote		abnormal eye anterior chamber depth	8.060887194005772E-5
Med25 Med25tm1b(KOMP)Wtsi	Open Field	Number of center entries	heterozygote		decreased locomotor activity	8.077366510406137E-5
Mbd5 Mbd5tm1b(EUCOMM)Wtsi	Open Field	Center distance travelled	heterozygote		decreased locomotor activity	8.077873644651845E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Number of center entries	homozygote		decreased locomotor activity	8.11111822258681E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Body Composition (DEXA lean/fat)	Bone Mineral Density (excluding skull)	hemizygote		decreased bone mineral density	8.130865899147466E-5
Dnm1l Dnm1ltm1b(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - hair distribution - head	heterozygote		abnormal coat/ hair morphology	8.159638673532754E-5
Hmgn1 Hmgn1em1(IMPC)Ics	Clinical Chemistry	Creatinine	homozygote		decreased circulating creatinine level	8.204314508475363E-5
Gpr101 Gpr101tm1b(KOMP)Mbp	Open Field	Percentage center movement time	hemizygote		decreased anxiety-related response	8.236259600380436E-5
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Heart Weight	Tibia length	homozygote		short tibia	8.263520430773497E-5
Rspo1 Rspo1tm2b(KOMP)Wtsi	Clinical Chemistry	Creatinine	homozygote		increased circulating creatinine level	8.275451546069235E-5
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi	Eye Morphology	Right inner nuclear layer	heterozygote		abnormal retina inner nuclear layer morphology	8.278941095340997E-5
Ncam2 Ncam2tm1b(EUCOMM)Hmgu	Echo	LVIDs	homozygote		dilated heart left ventricle	8.284815703518689E-5
Elk3 Elk3em1(IMPC)Ics	Clinical Chemistry	HDL-cholesterol	heterozygote		increased circulating HDL cholesterol level	8.298402826767415E-5
Prkab1 Prkab1tm1b(KOMP)Wtsi	Eye Morphology	Left total retinal thickness	homozygote		decreased total retina thickness	8.300253830384463E-5
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Open Field	Distance travelled - total	homozygote		decreased locomotor activity	8.304926450364292E-5
Cav1 Cav1em2(IMPC)Ics	Hematology	Mean corpuscular hemoglobin	homozygote		increased mean corpuscular hemoglobin	8.307708776555955E-5
Dbn1 Dbn1tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	8.340628119185567E-5
Bahd1 Bahd1tm2b(KOMP)Wtsi	Open Field	Number of center entries	heterozygote		decreased locomotor activity	8.398743375437334E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	homozygote		impaired glucose tolerance	8.410305599682033E-5
Mocos Mocosem2(IMPC)Ics	Clinical Chemistry	Total cholesterol	heterozygote		increased circulating cholesterol level	8.411757153226063E-5
Cdc26 Cdc26tm1b(EUCOMM)Hmgu	Echo	Fractional Shortening	heterozygote		increased cardiac muscle contractility	8.43682573758997E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Clinical Chemistry	Glucose	homozygote		increased circulating glucose level	8.45982285682112E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Clinical Chemistry	Creatinine	homozygote		decreased circulating creatinine level	8.46425537019968E-5
Rnf144b Rnf144btm1b(EUCOMM)Hmgu	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	8.499732939526439E-5
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Hematology	Mean cell volume	heterozygote		increased mean corpuscular volume	8.504481957061216E-5
Yipf5 Yipf5tm1b(EUCOMM)Hmgu	Hematology	Red blood cell count	heterozygote		decreased erythrocyte cell number	8.56477054185234E-5
Prkab1 Prkab1tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	homozygote		decreased grip strength	8.579831046517938E-5
Snx29 Snx29tm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	8.602344314567745E-5
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu	Auditory Brain Stem Response	6kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	8.602344314567745E-5
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	8.602344314567745E-5
Rspo1 Rspo1tm2b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	8.705400978215039E-5
Cav1 Cav1em2(IMPC)Ics	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	8.713949500815943E-5
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QRS	homozygote		shortened QRS complex duration	8.74812831170857E-5
Mocos Mocosem2(IMPC)Ics	Body Composition (DEXA lean/fat)	Fat mass	heterozygote		increased total body fat amount	8.750153938308358E-5
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi	Clinical Chemistry	Calcium	homozygote		increased circulating calcium level	8.754977898206562E-5
Cd276 Cd276tm2b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	8.831056038616225E-5
Laptm4a Laptm4atm1b(EUCOMM)Hmgu	Acoustic Startle and Pre-pulse Inhibition (PPI)	% Pre-pulse inhibition - PPI4	homozygote		increased prepulse inhibition	8.837931090965867E-5
Dnm1l Dnm1ltm1b(KOMP)Wtsi	Eye Morphology	Optic Disc	heterozygote		abnormal optic disk morphology	8.841968519845977E-5
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi	Eye Morphology	Optic Disc	homozygote		abnormal optic disk morphology	8.841968519845977E-5
Tmem108 Tmem108tm1b(EUCOMM)Wtsi	Body Composition (DEXA lean/fat)	Bone Mineral Content (excluding skull)	homozygote		increased bone mineral content	8.849360165186226E-5
Cbr3 Cbr3em1(IMPC)Ics	Combined SHIRPA and Dysmorphology	Locomotor activity	homozygote		decreased exploration in new environment	8.882016118150204E-5
App Apptm1b(KOMP)Wtsi	X-ray	Tibia length	heterozygote		short tibia	8.88733848114498E-5
Cstb Cstbtm1b(EUCOMM)Wtsi	Clinical Chemistry	Triglycerides	homozygote		increased circulating triglyceride level	8.890672324923798E-5
Kif5c Kif5ctm1dIcs	Clinical Chemistry	Total protein	heterozygote		increased circulating total protein level	8.911915210774168E-5
Rspo1 Rspo1tm2b(KOMP)Wtsi	Body Composition (DEXA lean/fat)	Lean/Body weight	homozygote		decreased lean body mass	8.94394688657485E-5
Rasal3 Rasal3tm1b(EUCOMM)Hmgu	Clinical Chemistry	Triglycerides	homozygote		increased circulating triglyceride level	8.968274050857872E-5
Epx Epxtm1b(EUCOMM)Wtsi	Hematology	Monocyte differential count	homozygote		increased monocyte cell number	8.973132207756862E-5
Knstrn Knstrntm1b(KOMP)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Fasted blood glucose concentration	homozygote		increased fasting circulating glucose level	8.996929682325572E-5
Pdlim4 Pdlim4em1(IMPC)Ics	Clinical Chemistry	Glucose	homozygote		decreased circulating glucose level	8.998357225209475E-5
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi	Combined SHIRPA and Dysmorphology	Coat - color pattern - abdomen	heterozygote		abnormal coat/hair pigmentation	9.018691343953833E-5
4933430I17Rik 4933430I17Riktm1a(EUCOMM)Wtsi	Hematology	Mean cell volume	homozygote		increased mean corpuscular volume	9.037653944687918E-5
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi	Hematology	Lymphocyte cell count	heterozygote		decreased lymphocyte cell number	9.118910384131595E-5
Ppp4c Ppp4cem1(IMPC)Ics	Fear Conditioning	% Freezing duration context-3	heterozygote		abnormal contextual conditioning behavior	9.11936440388672E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		increased startle reflex	9.122952178586274E-5
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Electrocardiogram (ECG)	QT	homozygote		prolonged QT interval	9.12912655621767E-5
Cdc27 Cdc27tm1dIcs	Body Composition (DEXA lean/fat)	Lean/Body weight	heterozygote		decreased lean body mass	9.206594404531643E-5
Med25 Med25tm1b(KOMP)Wtsi	Eye Morphology	Right total retinal thickness	heterozygote		decreased total retina thickness	9.219841012964025E-5
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Open Field	Center resting time	homozygote		decreased locomotor activity	9.255113400286064E-5
Setx Setxtm1b(EUCOMM)Wtsi	Hematology	White blood cell count	homozygote		decreased leukocyte cell number	9.292658069171011E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength measurement mean	heterozygote		decreased grip strength	9.312970360042527E-5
Cdh13 Cdh13tm1b(EUCOMM)Hmgu	Open Field	Center average speed	homozygote		hyperactivity	9.329611202701926E-5
Eftud2 Eftud2tm1b(KOMP)Wtsi	Grip Strength	Forelimb and hindlimb grip strength normalised against body weight	heterozygote		decreased grip strength	9.331661567557603E-5
Il2ra Il2ratm1b(EUCOMM)Wtsi	Fear Conditioning	% Freezing duration habituation-2	homozygote		abnormal locomotor behavior	9.36173673835583E-5
Morc3 Morc3tm1b(EUCOMM)Hmgu	Hematology	Hematocrit	heterozygote		decreased hematocrit	9.388236503582448E-5
Rnf10 Rnf10tm1b(KOMP)Wtsi	Intraperitoneal glucose tolerance test (IPGTT)	Area under glucose response curve	homozygote		improved glucose tolerance	9.412713552592322E-5
Lca5l Lca5lem1(IMPC)Ics	Hematology	Hemoglobin	homozygote		decreased hemoglobin content	9.420527931069955E-5
Cidea Cideatm1b(EUCOMM)Hmgu	Clinical Chemistry	Albumin	homozygote		increased circulating serum albumin level	9.43153427215293E-5
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi	Fear Conditioning	% Freezing duration context-2	heterozygote		abnormal contextual conditioning behavior	9.442286682315171E-5
Taf2 Taf2tm1b(EUCOMM)Hmgu	Clinical Chemistry	Cholesterol ratio	heterozygote		abnormal cholesterol homeostasis	9.504217450739816E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Persistence of hyaloid vascular system	homozygote		persistence of hyaloid vascular system	9.51105248532258E-5
Bscl2 Bscl2tm1b(EUCOMM)Hmgu	Intraperitoneal glucose tolerance test (IPGTT)	Initial response to glucose challenge	homozygote		improved glucose tolerance	9.52101981965825E-5
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi	Acoustic Startle and Pre-pulse Inhibition (PPI)	Response amplitude - S	heterozygote		decreased startle reflex	9.557861631037667E-5
Fam3b Fam3btm1b(EUCOMM)Hmgu	Open Field	Latency to center entry	homozygote		decreased exploration in new environment	9.58599557634443E-5
Pdpr Pdprtm1b(EUCOMM)Wtsi	Clinical Chemistry	Cholesterol ratio	homozygote		abnormal cholesterol homeostasis	9.589349065208808E-5
Lca5l Lca5lem1(IMPC)Ics	Hematology	Hematocrit	homozygote		decreased hematocrit	9.595209849067032E-5
Kcne1 Kcne1tm1b(EUCOMM)Hmgu	Body Composition (DEXA lean/fat)	Lean mass	homozygote		increased lean body mass	9.616309398552403E-5
Aak1 Aak1tm1b(EUCOMM)Hmgu	Fear Conditioning	% Freezing duration context-2	homozygote		abnormal contextual conditioning behavior	9.620055789127946E-5
Thra Thratm1b(EUCOMM)Wtsi	X-ray	Tibia length	heterozygote		short tibia	9.620228229323402E-5
Nab2 Nab2tm1b(EUCOMM)Hmgu	Open Field	Percentage center movement time	homozygote		increased anxiety-related response	9.622697689337656E-5
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu	Hematology	Large Unstained Cell (LUC) count	homozygote		decreased large unstained cell number	9.632152068661526E-5
Setx Setxtm1b(EUCOMM)Wtsi	Eye Morphology	Right total retinal thickness	homozygote		decreased total retina thickness	9.676147601567209E-5
Parp1 Parp1tm1b(EUCOMM)Hmgu	Immunophenotyping	NK cells (panel A)	homozygote		decreased NK cell number	9.684113319963217E-5
Hmgn1 Hmgn1em1(IMPC)Ics	Body Composition (DEXA lean/fat)	Lean mass	homozygote		decreased lean body mass	9.70390610746108E-5
Dbnl Dbnltm1b(KOMP)Wtsi	Eye Morphology	Left inner nuclear layer	homozygote		abnormal retina inner nuclear layer morphology	9.716184285935014E-5
Snx29 Snx29tm1b(EUCOMM)Hmgu	Indirect Calorimetry	Total food intake	homozygote		decreased food intake	9.732945181895047E-5
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl	Body Composition (DEXA lean/fat)	Lean mass	hemizygote		increased lean body mass	9.777098603080958E-5
Scaper Scapertm1b(EUCOMM)Hmgu	Clinical Chemistry	Urea (Blood Urea Nitrogen - BUN)	homozygote		decreased blood urea nitrogen level	9.83113786787726E-5
Ddr1 Ddr1tm1b(EUCOMM)Hmgu	Open Field	Whole arena average speed	heterozygote		hyperactivity	9.89399995887652E-5
Otub1 Otub1tm1b(EUCOMM)Hmgu	Eye Morphology	Left corneal thickness	heterozygote		increased cornea thickness	9.894355753203854E-5
Tiam1 Tiam1tm1b(EUCOMM)Hmgu	Eye Morphology	Right corneal thickness	homozygote		increased cornea thickness	9.958538430510089E-5
Padi3 Padi3tm1b(KOMP)Wtsi	Clinical Chemistry	HDL-cholesterol	homozygote		increased circulating HDL cholesterol level	9.97518072836101E-5
Ntf5 Ntf5tm1b(EUCOMM)Hmgu	Clinical Chemistry	Total protein	homozygote		increased circulating total protein level	9.982840128941461E-5
Obp2a Obp2atm1b(EUCOMM)Wtsi	Clinical Chemistry	Total cholesterol	homozygote		increased circulating cholesterol level	9.991669503506273E-5
Gp6 Gp6tm2b(EUCOMM)Hmgu	Auditory Brain Stem Response	12kHz-evoked ABR Threshold	homozygote		abnormal auditory brainstem response	2.4359601957257837E-4
Myo18b Myo18bem2(IMPC)Ics	Auditory Brain Stem Response	30kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	0.0021858587861061096
Phf6 Phf6tm1b(EUCOMM)Wtsi	Auditory Brain Stem Response	24kHz-evoked ABR Threshold	heterozygote		abnormal auditory brainstem response	0.06902985274791718