Significant MP calls for BCM Strains (IMPC_001)  

 

Total number of results: 83

Gene / Allele Procedure Parameter Zygosity Sex Phenotype P-value Graph
Gdpd5
Gdpd5tm1b(EUCOMM)Hmgu
Gross Pathology and Tissue Collection Spleen heterozygote Female abnormal spleen morphology 0.0
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Albumin homozygote Female decreased circulating serum albumin level 1.994981402297924E-10
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Albumin homozygote Male decreased circulating serum albumin level 1.994981402297924E-10
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female decreased total body fat amount 5.61164781309742E-10
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male decreased total body fat amount 5.61164781309742E-10
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female increased bone mineral content 1.946829142340789E-9
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Male increased bone mineral content 1.946829142340789E-9
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Calcium homozygote Female decreased circulating calcium level 7.848280247912953E-9
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Calcium homozygote Male decreased circulating calcium level 7.848280247912953E-9
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Fat mass homozygote Female decreased total body fat amount 1.2873703880700305E-8
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Fat mass homozygote Male decreased total body fat amount 1.2873703880700305E-8
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female increased bone mineral content 6.999288615361365E-8
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male increased bone mineral content 6.999288615361365E-8
Gdpd5
Gdpd5tm1b(EUCOMM)Hmgu
Grip Strength Forelimb grip strength normalised against body weight heterozygote Female decreased grip strength 1.3659450814884622E-7
Gdpd5
Gdpd5tm1b(EUCOMM)Hmgu
Grip Strength Forelimb grip strength normalised against body weight heterozygote Male decreased grip strength 1.3659450814884622E-7
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Total protein homozygote Female decreased circulating total protein level 1.474841866411225E-7
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Total protein homozygote Male decreased circulating total protein level 1.474841866411225E-7
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Alkaline phosphatase homozygote Female decreased circulating alkaline phosphatase level 1.8333180662466475E-7
Prdm14
Prdm14tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 2.528847176108684E-7
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Albumin homozygote Female decreased circulating serum albumin level 2.981344380259543E-7
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Albumin homozygote Male decreased circulating serum albumin level 2.981344380259543E-7
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Total protein homozygote Female decreased circulating total protein level 4.4379447672326933E-7
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Total protein homozygote Male decreased circulating total protein level 4.4379447672326933E-7
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Female decreased circulating alkaline phosphatase level 6.424626803891442E-7
Hibadh
Hibadhtm1b(EUCOMM)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Male decreased circulating alkaline phosphatase level 6.424626803891442E-7
Nek10
Nek10tm1b(KOMP)Wtsi
Clinical Chemistry Albumin homozygote Female decreased circulating serum albumin level 1.3916379657530342E-6
Nek10
Nek10tm1b(KOMP)Wtsi
Clinical Chemistry Albumin homozygote Male decreased circulating serum albumin level 1.3916379657530342E-6
Mthfd1
Mthfd1tm2b(KOMP)Wtsi
Clinical Chemistry Albumin heterozygote Female decreased circulating serum albumin level 1.4747619161425973E-6
Mthfd1
Mthfd1tm2b(KOMP)Wtsi
Clinical Chemistry Albumin heterozygote Male decreased circulating serum albumin level 1.4747619161425973E-6
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Calcium homozygote Female decreased circulating calcium level 1.4857359929010272E-6
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Calcium homozygote Male decreased circulating calcium level 1.4857359929010272E-6
Gcdh
Gcdhtm2b(EUCOMM)Hmgu
Grip Strength Forelimb and hindlimb grip strength normalised against body weight heterozygote Female increased grip strength 1.6336617818524246E-6
Gcdh
Gcdhtm2b(EUCOMM)Hmgu
Grip Strength Forelimb and hindlimb grip strength normalised against body weight heterozygote Male increased grip strength 1.6336617818524246E-6
Gcdh
Gcdhtm2b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Coat - hair texture / appearance - abdomen heterozygote Male abnormal coat appearance 1.7620369590076734E-6
Ddx39
Ddx39tm1b(KOMP)Wtsi
Clinical Chemistry Albumin heterozygote Female decreased circulating serum albumin level 1.8484455495126895E-6
Ddx39
Ddx39tm1b(KOMP)Wtsi
Clinical Chemistry Albumin heterozygote Male decreased circulating serum albumin level 1.8484455495126895E-6
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
Clinical Chemistry Total cholesterol homozygote Female increased circulating cholesterol level 2.4486844267812558E-6
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
Clinical Chemistry Total cholesterol homozygote Male increased circulating cholesterol level 2.4486844267812558E-6
Prdm14
Prdm14tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 2.478673877703841E-6
Mmp15
Mmp15tm1b(KOMP)Wtsi
Clinical Chemistry Calcium homozygote Female decreased circulating calcium level 2.6385080218460644E-6
Prdm14
Prdm14tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female increased total body fat amount 3.3745700420695357E-6
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Eye Morphology Right anterior chamber depth homozygote Female abnormal eye anterior chamber depth 3.686040372485877E-6
Prdm14
Prdm14tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 3.999371983809397E-6
Sbk2
Sbk2em1(IMPC)Bay
Clinical Chemistry Albumin homozygote Female decreased circulating serum albumin level 5.743387646361953E-6
Sbk2
Sbk2em1(IMPC)Bay
Clinical Chemistry Albumin homozygote Male decreased circulating serum albumin level 5.743387646361953E-6
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 5.954248535999795E-6
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Bone Area homozygote Male abnormal bone structure 5.954248535999795E-6
Memo1
Memo1tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat mass heterozygote Female decreased total body fat amount 9.986453733290546E-6
Memo1
Memo1tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat mass heterozygote Male decreased total body fat amount 9.986453733290546E-6
Gcdh
Gcdhtm2b(EUCOMM)Hmgu
Grip Strength Forelimb and hindlimb grip strength measurement mean heterozygote Female increased grip strength 1.0889542863878887E-5
Cilp
Cilptm1b(EUCOMM)Wtsi
Clinical Chemistry Alanine aminotransferase homozygote Female decreased circulating alanine transaminase level 1.2818341929232702E-5
Cilp
Cilptm1b(EUCOMM)Wtsi
Clinical Chemistry Alanine aminotransferase homozygote Male decreased circulating alanine transaminase level 1.2818341929232702E-5
Gdpd5
Gdpd5tm1b(EUCOMM)Hmgu
Grip Strength Forelimb grip strength measurement mean heterozygote Female decreased grip strength 1.314940436714096E-5
Gdpd5
Gdpd5tm1b(EUCOMM)Hmgu
Grip Strength Forelimb grip strength measurement mean heterozygote Male decreased grip strength 1.314940436714096E-5
Memo1
Memo1tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote Female decreased total body fat amount 1.32275017676875E-5
Memo1
Memo1tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote Male decreased total body fat amount 1.32275017676875E-5
Kcng2
Kcng2em1(IMPC)Bay
Clinical Chemistry Albumin homozygote Female decreased circulating serum albumin level 1.5490282748942263E-5
Kcng2
Kcng2em1(IMPC)Bay
Clinical Chemistry Albumin homozygote Male decreased circulating serum albumin level 1.5490282748942263E-5
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Echo LVAWs homozygote Female thin ventricular wall 1.7762204151949845E-5
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Echo LVAWs homozygote Male thin ventricular wall 1.7762204151949845E-5
Nanos2
Nanos2em1(IMPC)Bay
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Female increased blood urea nitrogen level 2.0857652998529375E-5
Nanos2
Nanos2em1(IMPC)Bay
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Male decreased blood urea nitrogen level 2.0857652998529375E-5
Prdm14
Prdm14tm1a(EUCOMM)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 2.2618129150941968E-5
Mapkap1
Mapkap1tm1a(EUCOMM)Wtsi
Electrocardiogram (ECG) QTc Dispersion heterozygote Female abnormal QT variability 2.405474879196845E-5
Mapkap1
Mapkap1tm1a(EUCOMM)Wtsi
Electrocardiogram (ECG) QTc Dispersion heterozygote Male abnormal QT variability 2.405474879196845E-5
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Female increased lean body mass 3.350858241901733E-5
Nr1d1
Nr1d1tm1(KOMP)Vlcg
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Male increased lean body mass 3.350858241901733E-5
Ddx39
Ddx39tm1b(KOMP)Wtsi
Clinical Chemistry Phosphorus heterozygote Female increased circulating phosphate level 3.717184881679714E-5
Ddx39
Ddx39tm1b(KOMP)Wtsi
Clinical Chemistry Phosphorus heterozygote Male increased circulating phosphate level 3.717184881679714E-5
Tfeb
Tfebtm1a(EUCOMM)Wtsi
Clinical Chemistry Alkaline phosphatase heterozygote Female decreased circulating alkaline phosphatase level 3.87080290238373E-5
Tfeb
Tfebtm1a(EUCOMM)Wtsi
Clinical Chemistry Alkaline phosphatase heterozygote Male decreased circulating alkaline phosphatase level 3.87080290238373E-5
Cox5b
Cox5btm2b(EUCOMM)Hmgu
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) heterozygote Female decreased blood urea nitrogen level 4.698803968494758E-5
Cox5b
Cox5btm2b(EUCOMM)Hmgu
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) heterozygote Male decreased blood urea nitrogen level 4.698803968494758E-5
Abca13
Abca13tm1b(EUCOMM)Wtsi
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Female decreased blood urea nitrogen level 6.40404032310471E-5
Abca13
Abca13tm1b(EUCOMM)Wtsi
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote Male decreased blood urea nitrogen level 6.40404032310471E-5
9930012K11Rik
9930012K11Riktm2b(EUCOMM)Hmgu
Clinical Chemistry Alanine aminotransferase homozygote Female decreased circulating alanine transaminase level 6.64127292111516E-5
9930012K11Rik
9930012K11Riktm2b(EUCOMM)Hmgu
Clinical Chemistry Alanine aminotransferase homozygote Male decreased circulating alanine transaminase level 6.64127292111516E-5
4931422A03Rik
4931422A03Riktm1b(EUCOMM)Wtsi
Clinical Chemistry Sodium homozygote Female decreased circulating sodium level 7.361795724136755E-5
4931422A03Rik
4931422A03Riktm1b(EUCOMM)Wtsi
Clinical Chemistry Sodium homozygote Male decreased circulating sodium level 7.361795724136755E-5
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Alanine aminotransferase homozygote Female decreased circulating alanine transaminase level 8.16476676845923E-5
Dnah1
Dnah1tm1b(EUCOMM)Hmgu
Clinical Chemistry Alanine aminotransferase homozygote Male decreased circulating alanine transaminase level 8.16476676845923E-5
Rims3
Rims3tm1b(KOMP)Wtsi
Clinical Chemistry Alanine aminotransferase homozygote Female decreased circulating alanine transaminase level 9.690823208075017E-5
Rims3
Rims3tm1b(KOMP)Wtsi
Clinical Chemistry Alanine aminotransferase homozygote Male decreased circulating alanine transaminase level 9.690823208075017E-5