Combined SHIRPA and Dysmorphology: Images

WT Images

9 weeks old

9 weeks old

9 weeks old

9 weeks old

9 weeks old

9 weeks old

Skin color - front paws: As expected

9 weeks old

Mutant Images

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

8 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

8 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

8 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

10 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindpaw - size: As expected,
Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

10 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

8 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

Comments (in English): Missing R eye

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

Comments (in English): R eye missing

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

10 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - increased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

10 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Tail - length: Short

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - increased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

8 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Tail - length: Short

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

8 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

8 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindpaw - size: As expected,
Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Hindlimb digit - size: Both hindlimbs - decreased size

9 weeks old

Dnase1l2tm1.1(KOMP)Wtsi homozygote

9 weeks old

Dnase1l2tm1(KOMP)Wtsi homozygote

Forelimb digit - size: Both forelimbs - decreased size

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