Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data Mammary gland - metaplasia Nr1d1 homozygote female Early adult Histopathology Mammary gland - MPATH process term BCM IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:2444210?anatomy="Mammary gland" Eye with optic nerve - process of degenerative change Nr1d1 homozygote female Early adult Histopathology Eye with optic nerve - MPATH process term BCM IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:2444210?anatomy="Eye with optic nerve" enlarged heart Nr1d1 homozygote female Early adult Gross Pathology and Tissue Collection Heart BCM IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2444210/IMPC_PAT_006_002 preweaning lethality, incomplete penetrance Nr1d1 homozygote female Early adult Viability Primary Screen Homozygous females viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:5548823&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=BCM unresponsive to tactile stimuli Nr1d1 heterozygote female E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:5548823&zygosity=heterozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM abnormal eye morphology Nr1d1 homozygote female Early adult Gross Pathology and Tissue Collection Eye with optic nerve BCM IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2444210/IMPC_PAT_002_002 Eye with optic nerve - process of degenerative change Nr1d1 homozygote male Early adult Histopathology Eye with optic nerve - MPATH process term BCM IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:2444210?anatomy="Eye with optic nerve" unresponsive to tactile stimuli Nr1d1 heterozygote male E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:5548823&zygosity=heterozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM preweaning lethality, incomplete penetrance Nr1d1 homozygote male Early adult Viability Primary Screen Homozygous males viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:5548823&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=BCM preweaning lethality, incomplete penetrance Nr1d1 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:5548823&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=BCM unresponsive to tactile stimuli Nr1d1 homozygote female E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:5548823&zygosity=homozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM unresponsive to tactile stimuli Nr1d1 homozygote male E18.5 Gross Morphology Embryo E18.5 Responsive to tactile stimuli BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:5548823&zygosity=homozygote¶meter_stable_id=IMPC_GEP_005_002&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_GEP_003¶meter_stable_id=IMPC_GEP_005_002&phenotyping_center=BCM decreased total retina thickness Nr1d1 homozygote female Early adult Eye Morphology Left total retinal thickness BCM IMPC 2.57E-22 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_068_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_068_001&phenotyping_center=BCM decreased total retina thickness Nr1d1 homozygote male Early adult Eye Morphology Left total retinal thickness BCM IMPC 4.53E-15 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_068_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_068_001&phenotyping_center=BCM abnormal eye posterior chamber depth Nr1d1 homozygote female Early adult Eye Morphology Right posterior chamber depth BCM IMPC 3.4E-11 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_065_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_065_001&phenotyping_center=BCM decreased total body fat amount Nr1d1 homozygote female Early adult Body Composition (DEXA lean/fat) Fat mass BCM IMPC 1.85E-10 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=BCM abnormal retina inner nuclear layer morphology Nr1d1 homozygote female Early adult Eye Morphology Left inner nuclear layer BCM IMPC 2.27E-10 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_069_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_069_001&phenotyping_center=BCM decreased cardiac output Nr1d1 homozygote male Early adult Echo Cardiac Output BCM IMPC 5.22E-10 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_ECH_006_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_ECH_001¶meter_stable_id=IMPC_ECH_006_001&phenotyping_center=BCM decreased total body fat amount Nr1d1 homozygote female Early adult Body Composition (DEXA lean/fat) Fat/Body weight BCM IMPC 1.5E-9 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=BCM abnormal eye posterior chamber depth Nr1d1 homozygote female Early adult Eye Morphology Left posterior chamber depth BCM IMPC 3.02E-9 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_071_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_071_001&phenotyping_center=BCM decreased total retina thickness Nr1d1 homozygote female Early adult Eye Morphology Right total retinal thickness BCM IMPC 1.61E-7 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_062_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_062_001&phenotyping_center=BCM increased bone mineral content Nr1d1 homozygote female Early adult Body Composition (DEXA lean/fat) BMC/Body weight BCM IMPC 5.87E-7 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_DXA_007_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_007_001&phenotyping_center=BCM decreased thigmotaxis Nr1d1 homozygote male Early adult Open Field - centre start Periphery permanence time BCM IMPC 1.18E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_OFD_012_001&pipeline_stable_id=BCM_001&procedure_stable_id=BCM_OFD_001¶meter_stable_id=IMPC_OFD_012_001&phenotyping_center=BCM increased circulating iron level Nr1d1 homozygote male Early adult Clinical Chemistry Iron ICS EuroPhenome 1.25E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=NOT-RELEASED-ad89a0b701&zygosity=homozygote¶meter_stable_id=ESLIM_015_001_011&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_015_001¶meter_stable_id=ESLIM_015_001_011&phenotyping_center=ICS decreased circulating alkaline phosphatase level Nr1d1 heterozygote female Early adult Clinical Chemistry Alkaline phosphatase ICS EuroPhenome 1.43E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=NOT-RELEASED-ad89a0b701&zygosity=heterozygote¶meter_stable_id=ESLIM_015_001_015&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_015_001¶meter_stable_id=ESLIM_015_001_015&phenotyping_center=ICS decreased NK cell number Nr1d1 homozygote male Early adult Immunophenotyping NK cells (panel A) BCM IMPC 1.6E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_IMM_005_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_IMM_001¶meter_stable_id=IMPC_IMM_005_001&phenotyping_center=BCM decreased total body fat amount Nr1d1 homozygote male Early adult Body Composition (DEXA lean/fat) Fat/Body weight BCM IMPC 2.18E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=BCM increased mean corpuscular volume Nr1d1 heterozygote female Early adult Haematology Mean cell volume ICS EuroPhenome 4.18E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=NOT-RELEASED-ad89a0b701&zygosity=heterozygote¶meter_stable_id=ESLIM_016_001_005&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_016_001¶meter_stable_id=ESLIM_016_001_005&phenotyping_center=ICS increased bone mineral content Nr1d1 homozygote female Early adult Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) BCM IMPC 5.48E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_DXA_005_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_005_001&phenotyping_center=BCM abnormal retina inner nuclear layer morphology Nr1d1 homozygote female Early adult Eye Morphology Right inner nuclear layer BCM IMPC 5.93E-6 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_063_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_063_001&phenotyping_center=BCM decreased total body fat amount Nr1d1 homozygote male Early adult Body Composition (DEXA lean/fat) Fat mass BCM IMPC 1.32E-5 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_DXA_002_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_002_001&phenotyping_center=BCM decreased hemoglobin content Nr1d1 heterozygote female Early adult Haematology Mean cell haemoglobin concentration ICS EuroPhenome 1.84E-5 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=NOT-RELEASED-ad89a0b701&zygosity=heterozygote¶meter_stable_id=ESLIM_016_001_007&pipeline_stable_id=ESLIM_002&procedure_stable_id=ESLIM_016_001¶meter_stable_id=ESLIM_016_001_007&phenotyping_center=ICS decreased total retina thickness Nr1d1 homozygote male Early adult Eye Morphology Right total retinal thickness BCM IMPC 2.7E-5 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_062_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_062_001&phenotyping_center=BCM abnormal eye anterior chamber depth Nr1d1 homozygote female Early adult Eye Morphology Right anterior chamber depth BCM IMPC 4.48E-5 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_EYE_061_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_061_001&phenotyping_center=BCM hyperactivity Nr1d1 homozygote not_considered Early adult Open Field - centre start Whole arena resting time BCM IMPC 5.05E-5 //www.mousephenotype.org/data/charts?accession=MGI:2444210&allele_accession_id=MGI:3847528&zygosity=homozygote¶meter_stable_id=IMPC_OFD_007_001&pipeline_stable_id=BCM_001&procedure_stable_id=BCM_OFD_001¶meter_stable_id=IMPC_OFD_007_001&phenotyping_center=BCM