Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, incomplete penetrance Nedd4l homozygote not_considered Early adult Viability Primary Screen Viability Outcome MRC Harwell IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_VIA_001_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_VIA_001¶meter_stable_id=IMPC_VIA_001_001&phenotyping_center=MRC Harwell abnormal startle reflex Nedd4l homozygote male Early adult Combined SHIRPA and Dysmorphology Startle response MRC Harwell IMPC 5.84E-13 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_CSD_036_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_036_001&phenotyping_center=MRC Harwell abnormal retina morphology Nedd4l homozygote male Early adult Eye Morphology Retina (combined) MRC Harwell IMPC 6.12E-11 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_EYE_092_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_092_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Nedd4l homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 MRC Harwell IMPC 3.82E-10 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_034_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_034_001&phenotyping_center=MRC Harwell abnormal auditory brainstem response Nedd4l homozygote not_considered Early adult Auditory Brain Stem Response 6kHz-evoked ABR Threshold MRC Harwell IMPC 3.53E-8 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ABR_004_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_004_001&phenotyping_center=MRC Harwell abnormal auditory brainstem response Nedd4l homozygote not_considered Early adult Auditory Brain Stem Response 18kHz-evoked ABR Threshold MRC Harwell IMPC 4.94E-8 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ABR_008_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_008_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Nedd4l homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI4 MRC Harwell IMPC 6.32E-8 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_036_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_036_001&phenotyping_center=MRC Harwell abnormal auditory brainstem response Nedd4l homozygote not_considered Early adult Auditory Brain Stem Response 12kHz-evoked ABR Threshold MRC Harwell IMPC 6.63E-8 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ABR_006_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_006_001&phenotyping_center=MRC Harwell abnormal auditory brainstem response Nedd4l homozygote not_considered Early adult Auditory Brain Stem Response 24kHz-evoked ABR Threshold MRC Harwell IMPC 6.7E-8 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ABR_010_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_010_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Nedd4l homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI4 MRC Harwell IMPC 9.46E-8 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_036_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_036_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Nedd4l homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global MRC Harwell IMPC 2.63E-7 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_037_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_037_001&phenotyping_center=MRC Harwell abnormal auditory brainstem response Nedd4l homozygote not_considered Early adult Auditory Brain Stem Response 30kHz-evoked ABR Threshold MRC Harwell IMPC 5.66E-7 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ABR_012_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_012_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Nedd4l homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 MRC Harwell IMPC 3.79E-6 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=MRC Harwell decreased locomotor activity Nedd4l homozygote not_considered Early adult Open Field Whole arena resting time MRC Harwell IMPC 9.68E-6 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_OFD_007_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_007_001&phenotyping_center=MRC Harwell abnormal auditory brainstem response Nedd4l homozygote not_considered Early adult Auditory Brain Stem Response Click-evoked ABR threshold MRC Harwell IMPC 2.85E-5 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ABR_002_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_002_001&phenotyping_center=MRC Harwell decreased startle reflex Nedd4l homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S MRC Harwell IMPC 3.63E-5 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_006_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_006_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Nedd4l homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 MRC Harwell IMPC 6.39E-5 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_034_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_034_001&phenotyping_center=MRC Harwell decreased prepulse inhibition Nedd4l homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global MRC Harwell IMPC 7.08E-5 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_ACS_037_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_037_001&phenotyping_center=MRC Harwell decreased exploration in new environment Nedd4l homozygote female Early adult Open Field Latency to center entry MRC Harwell IMPC 7.84E-5 //www.mousephenotype.org/data/charts?accession=MGI:1933754&allele_accession_id=MGI:5637104&zygosity=homozygote¶meter_stable_id=IMPC_OFD_018_001&pipeline_stable_id=HRWL_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_018_001&phenotyping_center=MRC Harwell