Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data abnormal spleen morphology Cul5 heterozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1922967/IMPC_PAT_016_002 preweaning lethality, complete penetrance Cul5 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=UC Davis preweaning lethality, complete penetrance Cul5 homozygote male Early adult Viability Primary Screen Homozygous males viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=UC Davis preweaning lethality, complete penetrance Cul5 homozygote female Early adult Viability Primary Screen Homozygous females viability UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=UC Davis pallor Cul5 homozygote female E9.5 Gross Morphology Embryo E9.5 Pallor UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_GEL_036_002&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_036_002&phenotyping_center=UC Davis embryonic lethality prior to tooth bud stage Cul5 homozygote not_considered E12.5 Viability E12.5 Secondary Screen Outcome UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_EVM_001_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EVM_001¶meter_stable_id=IMPC_EVM_001_001&phenotyping_center=UC Davis abnormal heart morphology Cul5 heterozygote male Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1922967/IMPC_PAT_006_002 enlarged spleen Cul5 heterozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1922967/IMPC_PAT_016_002 abnormal pericardium morphology Cul5 homozygote female E9.5 Gross Morphology Embryo E9.5 Pericardium Morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_GEL_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_006_001&phenotyping_center=UC Davis abnormal neural tube morphology Cul5 homozygote female E9.5 Gross Morphology Embryo E9.5 Neural tube morphology UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_GEL_060_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_060_001&phenotyping_center=UC Davis embryonic growth retardation Cul5 homozygote female E9.5 Gross Morphology Embryo E9.5 Delayed embryonic development UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_GEL_063_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_063_001&phenotyping_center=UC Davis abnormal embryo size Cul5 homozygote female E9.5 Gross Morphology Embryo E9.5 Embryo Size UC Davis IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=homozygote¶meter_stable_id=IMPC_GEL_032_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GEL_003¶meter_stable_id=IMPC_GEL_032_001&phenotyping_center=UC Davis enlarged heart Cul5 heterozygote male Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1922967/IMPC_PAT_006_002 increased spleen weight Cul5 heterozygote male Early adult Organ Weight Spleen weight UC Davis IMPC 3.34E-6 //www.mousephenotype.org/data/charts?accession=MGI:1922967&allele_accession_id=MGI:5569059&zygosity=heterozygote¶meter_stable_id=UCD_OWT_003_001&pipeline_stable_id=UCD_001&procedure_stable_id=UCD_OWT_001¶meter_stable_id=UCD_OWT_003_001&phenotyping_center=UC Davis