Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, complete penetrance Ascc2 homozygote male Early adult Viability Primary Screen Homozygous males viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922702&allele_accession_id=MGI:5548657&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=BCM embryonic lethality prior to organogenesis Ascc2 homozygote not_considered E9.5 Viability E9.5 Secondary Screen Outcome BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922702&allele_accession_id=MGI:5548657&zygosity=homozygote¶meter_stable_id=IMPC_EVL_001_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_EVL_001¶meter_stable_id=IMPC_EVL_001_001&phenotyping_center=BCM Heart - MPATH pathological process term hypertrophy Ascc2 heterozygote male Early adult Histopathology Heart - MPATH pathological process term BCM IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:1922702?anatomy="Heart" enlarged spleen Ascc2 heterozygote female Early adult Gross Pathology and Tissue Collection Spleen BCM IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1922702/IMPC_PAT_016_002 preweaning lethality, complete penetrance Ascc2 homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922702&allele_accession_id=MGI:5548657&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=BCM preweaning lethality, complete penetrance Ascc2 homozygote female Early adult Viability Primary Screen Homozygous females viability BCM IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:1922702&allele_accession_id=MGI:5548657&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=BCM enlarged spleen Ascc2 heterozygote female Early adult Gross Pathology and Tissue Collection Spleen BCM IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:1922702/IMPC_PAT_016_002 decreased heart left ventricle size Ascc2 heterozygote male Early adult Echo LVAWd BCM IMPC 1.05E-6 //www.mousephenotype.org/data/charts?accession=MGI:1922702&allele_accession_id=MGI:5548657&zygosity=heterozygote¶meter_stable_id=IMPC_ECH_007_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_ECH_001¶meter_stable_id=IMPC_ECH_007_001&phenotyping_center=BCM trunk curl Ascc2 heterozygote female Early adult Combined SHIRPA and Dysmorphology Trunk curl BCM IMPC 9.79E-5 //www.mousephenotype.org/data/charts?accession=MGI:1922702&allele_accession_id=MGI:5008937&zygosity=heterozygote¶meter_stable_id=IMPC_CSD_038_001&pipeline_stable_id=BCM_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_038_001&phenotyping_center=BCM